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Gene: Fn1 (fibronectin 1) Rattus norvegicus
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Symbol: Fn1
Name: fibronectin 1
Description: Exhibits mercury ion binding activity and protease binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to lipid; and cellular response to peptide. Localizes to the basement membrane and extracellular space. Used to study diabetic angiopathy and renovascular hypertension. Biomarker of several diseases, including VACTERL association; iron deficiency anemia; membranoproliferative glomerulonephritis; submandibular gland disease; and ureteral obstruction. Human ortholog(s) of this gene implicated in membranoproliferative glomerulonephritis. Orthologous to human FN1 (fibronectin 1); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-(5-isoquinolinesulfonyl)-2-methylpiperazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FIBNEC; fibronectin; fibronectin 2; fibronectin 3; FN; fn-1
Orthologs:
Homo sapiens (human) : FN1 (fibronectin 1)  HGNC  Alliance
Mus musculus (house mouse) : Fn1 (fibronectin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fn1 (fibronectin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FN1 (fibronectin 1)
Canis lupus familiaris (dog) : FN1 (fibronectin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fn1 (fibronectin 1)
Sus scrofa (pig) : FN1 (fibronectin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0978,900,111 - 78,969,018 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0978,674,437 - 78,743,423 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4970,702,181 - 70,771,155 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1970,849,162 - 70,918,137 (-)NCBI
Celera970,607,233 - 70,675,716 (-)NCBICelera
Cytogenetic Map9q33NCBI
RH 3.4 Map9673.9RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)