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Gene: Tmem198 (transmembrane protein 198) Rattus norvegicus

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Symbol:

Tmem198

Name:

transmembrane protein 198

RGD ID:

2319152

Description:

Predicted to be involved in positive regulation of canonical Wnt signaling pathway. Predicted to be active in cytoplasmic vesicle and plasma membrane. Orthologous to human TMEM198 (transmembrane protein 198); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; gentamycin; paracetamol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC100361928

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM198 (transmembrane protein 198)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tmem198 (transmembrane protein 198)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem198 (transmembrane protein 198)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM198 (transmembrane protein 198)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM198 (transmembrane protein 198)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem198 (transmembrane protein 198)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM198 (transmembrane protein 198)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM198 (transmembrane protein 198)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem198 (transmembrane protein 198)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	OBSL1 (obscurin like cytoskeletal adaptor 1)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	TMEM198 (transmembrane protein 198)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tmem198 (transmembrane protein 198)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tmem198b (transmembrane protein 198b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	tmem198a (transmembrane protein 198a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG14234	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tmem198	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	84,416,741 - 84,422,759 (+)	NCBI		GRCr8
mRatBN7.2	9	76,968,079 - 76,974,131 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	76,968,107 - 77,033,011 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	82,673,959 - 82,680,151 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	82,674,202 - 82,679,626 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	82,443,736 - 82,449,412 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	74,755,562 - 74,760,171 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	74,537,837 - 74,544,029 (+)	NCBI		Celera
Cytogenetic Map	9	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alacrima, achalasia, and impaired intellectual development syndrome (ISO)

cerebrotendinous xanthomatosis (ISO)

Neurodevelopmental Disorders (ISO)

paroxysmal nonkinesigenic dyskinesia 1 (ISO)

polydactyly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

bisphenol F (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

gentamycin (EXP)

paracetamol (EXP)

paraquat (ISO)

perfluorooctanoic acid (ISO)

resveratrol (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of canonical Wnt signaling pathway (IBA,ISO)

Cellular Component

cytoplasmic vesicle (IBA,ISO)

plasma membrane (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:21536646

Genomics

Comparative Map Data

Tmem198
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	84,416,741 - 84,422,759 (+)	NCBI		GRCr8
mRatBN7.2	9	76,968,079 - 76,974,131 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	76,968,107 - 77,033,011 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	82,673,959 - 82,680,151 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	82,674,202 - 82,679,626 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	82,443,736 - 82,449,412 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	74,755,562 - 74,760,171 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	74,537,837 - 74,544,029 (+)	NCBI		Celera
Cytogenetic Map	9	q33	NCBI

TMEM198
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	219,543,663 - 219,550,595 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	219,543,663 - 219,550,595 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	220,408,385 - 220,415,317 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	220,116,989 - 220,123,561 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	214,178,708 - 214,185,280 (+)	NCBI		Celera
Cytogenetic Map	2	q35	NCBI
HuRef	2	212,261,774 - 212,268,347 (+)	NCBI		HuRef
CHM1_1	2	220,414,567 - 220,421,138 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	220,028,362 - 220,035,294 (+)	NCBI		T2T-CHM13v2.0

Tmem198
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	75,456,115 - 75,462,337 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	75,456,176 - 75,462,349 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	75,479,532 - 75,485,693 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	75,479,532 - 75,485,705 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	75,476,107 - 75,482,268 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	75,362,728 - 75,368,853 (+)	NCBI		MGSCv36	mm8
Celera	1	75,968,943 - 75,975,052 (+)	NCBI		Celera
Cytogenetic Map	1	C4	NCBI
cM Map	1	39.15	NCBI

Tmem198
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	13,924,608 - 13,932,557 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	13,925,939 - 13,932,557 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM198
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	122,173,981 - 122,180,770 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	122,189,158 - 122,195,737 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	106,801,303 - 106,807,872 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	225,391,334 - 225,397,937 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	225,391,343 - 225,397,937 (+)	Ensembl	panpan1.1		panPan2

TMEM198
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	26,053,469 - 26,059,579 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	26,052,168 - 26,058,810 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	26,878,981 - 26,885,022 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	26,068,614 - 26,074,655 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	26,067,263 - 26,073,887 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	25,972,477 - 25,978,538 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	25,908,597 - 25,914,654 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	25,929,159 - 25,935,245 (+)	NCBI		UU_Cfam_GSD_1.0

Tmem198
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	175,581,143 - 175,587,272 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936569	1,924,002 - 1,930,058 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936569	1,923,924 - 1,930,058 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM198
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	121,553,694 - 121,559,869 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	121,553,686 - 121,559,860 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	134,533,570 - 134,588,040 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM198
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	105,439,006 - 105,445,667 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	105,439,176 - 105,444,927 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	93,955,575 - 93,962,130 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem198
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624823	5,511,475 - 5,517,681 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624823	5,511,326 - 5,518,032 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tmem198
11 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	119
Count of miRNA genes:	92
Interacting mature miRNAs:	102
Transcripts:	ENSRNOT00000027208
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	32535505	77535505	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	25268044	79271759	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	62072275	96470995	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
10058949	Gmadr5	Adrenal mass QTL 5	2	0.014	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	9	42791513	87976209	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	62072275	96470995	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	55847841	77026453	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	42495343	79271511	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	36962359	77814038	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	22071169	86369743	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	23754144	83851531	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	40194188	85194188	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56627713	78595166	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
11353949	Bp393	Blood pressure QTL 393			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	40194188	85194188	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	32535505	77535505	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	87	86	55	25	55	6	214	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001433363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001433364	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001433365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001433366	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_002730042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003754539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063268162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027208 ⟹ ENSRNOP00000027208

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	76,968,107 - 77,033,011 (+)	Ensembl
Rnor_6.0 Ensembl	9	82,674,202 - 82,679,626 (+)	Ensembl

RefSeq Acc Id:

XM_002730042 ⟹ XP_002730088

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,416,741 - 84,422,759 (+)	NCBI
mRatBN7.2	9	76,968,094 - 76,974,131 (+)	NCBI
Rnor_6.0	9	82,673,959 - 82,680,151 (+)	NCBI
Rnor_5.0	9	82,443,736 - 82,449,412 (+)	NCBI
RGSC_v3.4	9	74,755,562 - 74,760,171 (+)	RGD

Sequence:

show sequence

GCTACCAGAAAGGGAAGAGGGGAGGAGGTTAAAGGGGAAGGACCCCCGGAAGTGCCCCCTCCTC
AGCGCCGGAGAGGCAGACGCGGGGGGCGGAGTCTCCTGTCTCCCCCTGCGTGGTTGGTGCGTCC
CGGATGACGTCAAAGCAGCCCGCCCCTGCCAGGATGGTGCACCCTGAGTGACGTCAGGAGCAGA
GGCCGGAGCTGTCCATCAGCACCAAAGGCCGCCGGCGGGCTCAGGGCATGGGGCCGCGCTCCGG
GACAGCCCGAGCTCCTGCTCCTTTCTCTTCCCCGGGCCGGGCCCGAGTCACCGGACTGTGGGGC
TGCAGTGCCAGCGGGTGTTGGAGGTGGGGCGACGACGCCGTCGCACAGAGACCCGTCTCTCCGG
CCCAGCAACCCCCTTCGCACGGAGGACTTTGCCCGGACCCCAGTTAGTCGGAGCCTCTGGCGTC
CAACAACCTCCGATCCTCCGGCCCTGCACACCCTCCTTTGCTCGGAAGCTCGGGTCACCTCCAG
CCCAGGTTGTCCTGGGAGGGTGACCCTCCTTCATTCCCAGCACTATGCCGGGTACTATGGAAAC
TCTGCGGTTTCAGCTGCTGCCCCCGGAGCCGGATGATACCTTCTGGGGTGCACCTTGTCAACAG
CCTCTGGAGCGCAGGTATCAGGCACTGCCTGCCCTCGTCTGCATCATGTGCTGCTTGTTTGGAG
TCGTCTACTGCTTCTTTGGTTACCGCTGCTTCAAGGCTGTACTCTTCCTCACTGGGTTGCTGTT
TGGCTCAGTGGTTATCTTCCTGTTGTGCTACCGAGAGCGGGTTCTGGAGACGCAGCTGAGTGCT
GGGGCAAGCGCGGGCATCGCACTGGGCATTGGACTGCTCTGCGGACTGGTAGCCATGCTGGTAC
GCAGCGTGGGCCTCTTCCTGGTGGGGCTACTGCTCGGTCTGCTGCTCGCTGCTGCTGCCCTACT
AGGCTCCGCACCCTATTACCAGCCTGGCTCCGTATGGGGCCCACTGGGGCTGCTGCTGGGAGGC
GGCCTGCTCTGTGCCCTGCTCACGCTGCGCTGGCCCCGGCCACTCACCACCCTTGCCACTGCCG
TGACGGGTGCTGCACTCATTGCCACCGCCGCAGACTATTTTGCCGAACTGCTACTGCTGGGGCG
CTACGTGGTGGAGCGATTGCGGGCTGCCCCTGTGCCTCCCCTCTGCTGGCGGAGCTGGGCCCTG
CTGGCACTCTGGCCTCTCCTTAGCCTGATGGGCGTTCTGGTGCAGTGGAGGGTGACAACCGAGA
GGGACTCCCACACGGAAGTGGTCATCAGCCGGCAGCGAAGGCGAGTGCAGCTGATGAGGATCCG
GCAGCAGGAAGAACGCAAGGAGAAGCGGCGGAAGAAGAGACCCCCTCGGGCTCCTCCCAGAGGT
CCTCGGGCACCTCCAAGGCCTGGTCCCCCTGACCCTGCTTATAGACGCAGGCCAGTGCCCATTA
AACGCTTCAATGGAGATGTTCTCTCCCCGAGTTACATCCAGAGCTTCCGGGACCGGCAAACTGG
GAGCTCTCTGAGCTCCTTCATGGCCTCACCTACAGACACGGACTATGAGTATGGGTCCCGGGGA
CCACTGACAGCCTGCTCGGGACCCCCTGTACGGGTGTAGTCATGTTCCCGCTGTCTGGGCTCTC
CAGTCACCAGCTCTGACATCTTCGAGACGCCTGCCAGGCCACTACTGAGGCTGCAAGGCCCTGT
GGCCTTTGGCTGTCTCGCCTCCTTGGAGAGGGTTGGCCAGCCACCAAAAGGGAGGCTGCGTCTC
AGGCTAGGTAGGCCTGGCCTGAGGGAGAAGTTCCCGTCCAAGCTCCCGAGGGACTCGGGGTGTG
AGCCCCATTGGGATGTGCTCAGGGTTGTGTGTTGCCCATACATGTGTGTGAAGGGGTAGGCTTG
GCGGGGATACTGGGACCCTTGCCTTAGATTTGACTGGCAGGGCTTCTTCAGGGCCAGCTCCGCC
TCCTGTCCCCGCTGCTGGGGTCCCATGGGCCACTCTCCTGCATGTCTGTGTGGAGGAGGCCCAC
CCGCCTCCCCTACTGCTCTACCTTCCAACCATTCATCTAAGGGTTCTTGTTATTGTCCACGGGA
CTGATAGCAGCACTCCTCACCCTGGTCCCCTGACCTCTGCAAAGCCACCAGCCTGAGGGCAGTG
GCAGAGGATGAGGGTGAGGGGTGCTGTTCTGGGTTGGGTTTGGGAGGGTGGAGGGGAAAGGGCT
TAAATGCACGGTGCATGTCTGGTGTCTGCTATGCCACCTTAGACACCTCATGCTTCTGTCTCCT
CCCGCCCTGTTTTACATCTTTTATAAATGTGCCAAACTATGCGGCCTCTGCCAGAA

hide sequence

RefSeq Acc Id:

XM_039084658 ⟹ XP_038940586

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,416,752 - 84,422,759 (+)	NCBI
mRatBN7.2	9	76,968,079 - 76,974,114 (+)	NCBI

RefSeq Acc Id:

XM_063268162 ⟹ XP_063124232

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,416,752 - 84,422,759 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001420292	(Get FASTA)	NCBI Sequence Viewer
	NP_001420293	(Get FASTA)	NCBI Sequence Viewer
	NP_001420294	(Get FASTA)	NCBI Sequence Viewer
	NP_001420295	(Get FASTA)	NCBI Sequence Viewer
	XP_002730088	(Get FASTA)	NCBI Sequence Viewer
	XP_038940586	(Get FASTA)	NCBI Sequence Viewer
	XP_063124232	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027208.3

RefSeq Acc Id:

XP_002730088 ⟸ XM_002730042

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPGTMETLRFQLLPPEPDDTFWGAPCQQPLERRYQALPALVCIMCCLFGVVYCFFGYRCFKAVL
FLTGLLFGSVVIFLLCYRERVLETQLSAGASAGIALGIGLLCGLVAMLVRSVGLFLVGLLLGLL
LAAAALLGSAPYYQPGSVWGPLGLLLGGGLLCALLTLRWPRPLTTLATAVTGAALIATAADYFA
ELLLLGRYVVERLRAAPVPPLCWRSWALLALWPLLSLMGVLVQWRVTTERDSHTEVVISRQRRR
VQLMRIRQQEERKEKRRKKRPPRAPPRGPRAPPRPGPPDPAYRRRPVPIKRFNGDVLSPSYIQS
FRDRQTGSSLSSFMASPTDTDYEYGSRGPLTACSGPPVRV

hide sequence

Ensembl Acc Id:

ENSRNOP00000027208 ⟸ ENSRNOT00000027208

RefSeq Acc Id:	XP_038940586 ⟸ XM_039084658
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063124232 ⟸ XM_063268162
- Peptide Label:	isoform X3

Protein Domains

DUF4203

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZHB8-F1-model_v2	AlphaFold	D3ZHB8	1-360	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2319152	AgrOrtholog
BioCyc Gene	G2FUF-27060	BioCyc
Ensembl Genes	ENSRNOG00000020061	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000027208.6	UniProtKB/TrEMBL
InterPro	DUF4203	UniProtKB/TrEMBL
	TMEM198	UniProtKB/TrEMBL
KEGG Report	rno:100361928	UniProtKB/TrEMBL
NCBI Gene	100361928	ENTREZGENE
PANTHER	PTHR31247	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 198	UniProtKB/TrEMBL
Pfam	DUF4203	UniProtKB/TrEMBL
PhenoGen	Tmem198	PhenoGen
RatGTEx	ENSRNOG00000020061	RatGTEx
UniProt	A6JW38	ENTREZGENE, UniProtKB/TrEMBL
	D3ZHB8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-08-24	Tmem198	transmembrane protein 198	LOC100361928	transmembrane protein 198	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-05	LOC100361928	transmembrane protein 198			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar