Gmppa (GDP-mannose pyrophosphorylase A) - Rat Genome Database

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Gene: Gmppa (GDP-mannose pyrophosphorylase A) Rattus norvegicus
Analyze
Symbol: Gmppa
Name: GDP-mannose pyrophosphorylase A
RGD ID: 1560644
Description: Predicted to enable mannose-1-phosphate guanylyltransferase (GTP) activity. Predicted to be involved in several processes, including negative regulation of nucleobase-containing compound metabolic process; negative regulation of phosphorus metabolic process; and negative regulation of small molecule metabolic process. Predicted to act upstream of or within several processes, including GDP-mannose biosynthetic process; motor behavior; and neuron apoptotic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in alacrima, achalasia, and impaired intellectual development syndrome. Orthologous to human GMPPA (GDP-mannose pyrophosphorylase A); PARTICIPATES IN amino sugar metabolic pathway; fructose and mannose metabolic pathway; nucleotide sugar metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GTP-mannose-1-phosphate guanylyltransferase alpha; mannose-1-phosphate guanyltransferase alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8984,375,373 - 84,382,917 (+)NCBIGRCr8
mRatBN7.2976,926,724 - 76,934,274 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,926,739 - 76,934,269 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx985,371,310 - 85,378,586 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,500,190 - 90,507,467 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,886,366 - 88,893,642 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,632,267 - 82,639,811 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,632,230 - 82,639,821 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0982,401,531 - 82,409,072 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,713,604 - 74,721,031 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera974,496,780 - 74,504,202 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:5946626   PMID:22871113   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Gmppa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8984,375,373 - 84,382,917 (+)NCBIGRCr8
mRatBN7.2976,926,724 - 76,934,274 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,926,739 - 76,934,269 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx985,371,310 - 85,378,586 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,500,190 - 90,507,467 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,886,366 - 88,893,642 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,632,267 - 82,639,811 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,632,230 - 82,639,821 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0982,401,531 - 82,409,072 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,713,604 - 74,721,031 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera974,496,780 - 74,504,202 (+)NCBICelera
Cytogenetic Map9q33NCBI
GMPPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,498,891 - 219,506,989 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,498,865 - 219,513,898 (+)EnsemblGRCh38hg38GRCh38
GRCh372220,363,613 - 220,371,711 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,071,857 - 220,079,955 (+)NCBINCBI36Build 36hg18NCBI36
Celera2214,133,579 - 214,141,710 (+)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2212,216,657 - 212,224,788 (+)NCBIHuRef
CHM1_12220,369,431 - 220,377,562 (+)NCBICHM1_1
T2T-CHM13v2.02219,983,636 - 219,991,734 (+)NCBIT2T-CHM13v2.0
Gmppa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39175,412,555 - 75,419,823 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl175,412,574 - 75,419,823 (+)EnsemblGRCm39 Ensembl
GRCm38175,435,911 - 75,443,179 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl175,435,930 - 75,443,179 (+)EnsemblGRCm38mm10GRCm38
MGSCv37175,432,518 - 75,439,751 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36175,319,132 - 75,326,321 (+)NCBIMGSCv36mm8
Celera175,926,888 - 75,934,237 (+)NCBICelera
Cytogenetic Map1C4NCBI
cM Map139.04NCBI
Gmppa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545313,965,174 - 13,974,789 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545313,967,118 - 13,974,351 (-)NCBIChiLan1.0ChiLan1.0
GMPPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213122,128,991 - 122,137,162 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B122,143,986 - 122,152,130 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B106,756,115 - 106,764,280 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B225,345,983 - 225,354,116 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B225,346,029 - 225,354,116 (+)Ensemblpanpan1.1panPan2
GMPPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13726,010,531 - 26,017,798 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3726,010,638 - 26,017,787 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3726,836,061 - 26,843,269 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03726,025,650 - 26,032,850 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3726,025,704 - 26,033,700 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,929,609 - 25,936,812 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,865,687 - 25,872,896 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,886,247 - 25,893,449 (+)NCBIUU_Cfam_GSD_1.0
Gmppa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303175,539,181 - 175,546,398 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365691,881,774 - 1,889,932 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365691,881,975 - 1,889,179 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GMPPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15121,507,564 - 121,515,300 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115121,507,560 - 121,515,299 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215134,627,448 - 134,635,194 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GMPPA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110105,393,869 - 105,401,997 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10105,393,891 - 105,402,008 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604093,998,985 - 94,007,127 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gmppa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248235,550,014 - 5,559,812 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248235,552,044 - 5,559,037 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gmppa
46 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:53
Count of miRNA genes:52
Interacting mature miRNAs:53
Transcripts:ENSRNOT00000027064
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)95662771378595166Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat

Markers in Region
D9Mco51  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,929,328 - 76,929,514 (+)MAPPERmRatBN7.2
Rnor_6.0982,634,869 - 82,635,054NCBIRnor6.0
Rnor_5.0982,404,130 - 82,404,315UniSTSRnor5.0
RGSC_v3.4974,716,089 - 74,716,274UniSTSRGSC3.4
Celera974,499,259 - 74,499,444UniSTS
Cytogenetic Map9q33UniSTS
D9Mco52  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,933,733 - 76,933,905 (+)MAPPERmRatBN7.2
Rnor_6.0982,639,275 - 82,639,446NCBIRnor6.0
Rnor_5.0982,408,536 - 82,408,707UniSTSRnor5.0
RGSC_v3.4974,720,495 - 74,720,666UniSTSRGSC3.4
Celera974,503,666 - 74,503,837UniSTS
Cytogenetic Map9q33UniSTS
RH128732  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,934,031 - 76,934,214 (+)MAPPERmRatBN7.2
Rnor_6.0982,639,573 - 82,639,755NCBIRnor6.0
Rnor_5.0982,408,834 - 82,409,016UniSTSRnor5.0
RGSC_v3.4974,720,793 - 74,720,975UniSTSRGSC3.4
Celera974,503,964 - 74,504,146UniSTS
RH 3.4 Map9713.29UniSTS
Cytogenetic Map9q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 57 41 19 41 1 4 69 35 40 11 1
Low 8 7 7 5 1 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000027064   ⟹   ENSRNOP00000027064
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,926,844 - 76,934,269 (+)Ensembl
Rnor_6.0 Ensembl982,632,384 - 82,639,810 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085165   ⟹   ENSRNOP00000074442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,926,739 - 76,934,210 (+)Ensembl
Rnor_6.0 Ensembl982,632,230 - 82,639,821 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109761   ⟹   ENSRNOP00000078288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,926,844 - 76,934,269 (+)Ensembl
RefSeq Acc Id: NM_001025056   ⟹   NP_001020227
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,375,490 - 84,382,917 (+)NCBI
mRatBN7.2976,926,844 - 76,934,270 (+)NCBI
Rnor_6.0982,632,384 - 82,639,811 (+)NCBI
Rnor_5.0982,401,531 - 82,409,072 (+)NCBI
RGSC_v3.4974,713,604 - 74,721,031 (+)RGD
Celera974,496,780 - 74,504,202 (+)RGD
Sequence:
RefSeq Acc Id: XM_006245271   ⟹   XP_006245333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,375,373 - 84,382,917 (+)NCBI
mRatBN7.2976,926,725 - 76,934,274 (+)NCBI
Rnor_6.0982,632,267 - 82,639,811 (+)NCBI
Rnor_5.0982,401,531 - 82,409,072 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063267627   ⟹   XP_063123697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,375,434 - 84,382,917 (+)NCBI
RefSeq Acc Id: XM_063267628   ⟹   XP_063123698
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,375,437 - 84,382,917 (+)NCBI
RefSeq Acc Id: XM_063267630   ⟹   XP_063123700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,375,387 - 84,382,917 (+)NCBI
RefSeq Acc Id: XM_063267631   ⟹   XP_063123701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,375,661 - 84,382,917 (+)NCBI
RefSeq Acc Id: XM_063267632   ⟹   XP_063123702
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,375,482 - 84,382,917 (+)NCBI
RefSeq Acc Id: XR_010054629
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,375,434 - 84,382,221 (+)NCBI
RefSeq Acc Id: NP_001020227   ⟸   NM_001025056
- UniProtKB: Q5XIC1 (UniProtKB/Swiss-Prot),   A6JW33 (UniProtKB/TrEMBL),   A0A8I5ZKL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245333   ⟸   XM_006245271
- Peptide Label: isoform X1
- UniProtKB: Q5XIC1 (UniProtKB/Swiss-Prot),   A6JW33 (UniProtKB/TrEMBL),   A0A8I5ZKL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074442   ⟸   ENSRNOT00000085165
RefSeq Acc Id: ENSRNOP00000027064   ⟸   ENSRNOT00000027064
RefSeq Acc Id: ENSRNOP00000078288   ⟸   ENSRNOT00000109761
RefSeq Acc Id: XP_063123700   ⟸   XM_063267630
- Peptide Label: isoform X1
- UniProtKB: Q5XIC1 (UniProtKB/Swiss-Prot),   A0A8I5ZKL2 (UniProtKB/TrEMBL),   A6JW33 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123697   ⟸   XM_063267627
- Peptide Label: isoform X1
- UniProtKB: Q5XIC1 (UniProtKB/Swiss-Prot),   A0A8I5ZKL2 (UniProtKB/TrEMBL),   A6JW33 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123698   ⟸   XM_063267628
- Peptide Label: isoform X1
- UniProtKB: Q5XIC1 (UniProtKB/Swiss-Prot),   A0A8I5ZKL2 (UniProtKB/TrEMBL),   A6JW33 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123702   ⟸   XM_063267632
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZKL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123701   ⟸   XM_063267631
- Peptide Label: isoform X1
- UniProtKB: Q5XIC1 (UniProtKB/Swiss-Prot),   A0A8I5ZKL2 (UniProtKB/TrEMBL),   A6JW33 (UniProtKB/TrEMBL)
Protein Domains
Nucleotidyl transferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIC1-F1-model_v2 AlphaFold Q5XIC1 1-420 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696796
Promoter ID:EPDNEW_R7305
Type:multiple initiation site
Name:Gmppa_1
Description:GDP-mannose pyrophosphorylase A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0982,632,329 - 82,632,389EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560644 AgrOrtholog
BioCyc Gene G2FUF-27069 BioCyc
Ensembl Genes ENSRNOG00000019946 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055010546 UniProtKB/Swiss-Prot
  ENSRNOG00060008709 UniProtKB/Swiss-Prot
  ENSRNOG00065008539 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027064 ENTREZGENE
  ENSRNOT00000027064.5 UniProtKB/Swiss-Prot
  ENSRNOT00000085165.2 UniProtKB/TrEMBL
  ENSRNOT00000109761.1 UniProtKB/TrEMBL
  ENSRNOT00055017869 UniProtKB/Swiss-Prot
  ENSRNOT00060014587 UniProtKB/Swiss-Prot
  ENSRNOT00065013554 UniProtKB/Swiss-Prot
Gene3D-CATH Hexapeptide repeat proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7193128 IMAGE-MGC_LOAD
InterPro Hexapep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hexapep_transf_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTP_transferase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:501167 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94705 IMAGE-MGC_LOAD
NCBI Gene 501167 ENTREZGENE
PANTHER MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUGAR-1-PHOSPHATE GUANYL TRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hexapep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTP_transferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gmppa PhenoGen
PROSITE HEXAPEP_TRANSFERASES UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019946 RatGTEx
  ENSRNOG00055010546 RatGTEx
  ENSRNOG00060008709 RatGTEx
  ENSRNOG00065008539 RatGTEx
Superfamily-SCOP SSF53448 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K824_RAT UniProtKB/TrEMBL
  A0A8I5ZKL2 ENTREZGENE, UniProtKB/TrEMBL
  A6JW33 ENTREZGENE, UniProtKB/TrEMBL
  A6JW34_RAT UniProtKB/TrEMBL
  GMPPA_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-02-09 Gmppa  GDP-mannose pyrophosphorylase A      Symbol and Name status set to provisional 70820 PROVISIONAL