Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cxcr1 (C-X-C motif chemokine receptor 1) Rattus norvegicus
Symbol: Cxcr1
Name: C-X-C motif chemokine receptor 1
Description: Predicted to have chemokine binding activity and chemokine receptor activity. Predicted to be involved in several processes, including neutrophil chemotaxis; positive regulation of cytosolic calcium ion concentration; and receptor internalization. Predicted to localize to the external side of plasma membrane. Biomarker of membranoproliferative glomerulonephritis. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease and pyelonephritis. Orthologous to human CXCR1 (C-X-C motif chemokine receptor 1); INTERACTS WITH ammonium chloride; benzamide; bisphenol A.
Type: protein-coding
Also known as: C-X-C chemokine receptor type 1; chemokine (C-X-C motif) receptor 1; CXC-R1; CXCR-1; high affinity interleukin-8 receptor A; IL-8R A; Il8ra; interleukin 8 receptor, alpha
Homo sapiens (human) : CXCR1 (C-X-C motif chemokine receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Cxcr1 (chemokine (C-X-C motif) receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cxcr1 (C-X-C motif chemokine receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CXCR1 (C-X-C motif chemokine receptor 1)
Canis lupus familiaris (dog) : CXCR1 (chemokine (C-X-C motif) receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cxcr1 (C-X-C motif chemokine receptor 1)
Chlorocebus sabaeus (African green monkey) : CXCR1 (C-X-C motif chemokine receptor 1)
Heterocephalus glaber (naked mole-rat) : Cxcr1 (C-X-C motif chemokine receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0981,466,430 - 81,469,299 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,466,332 - 81,469,274 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,232,019 - 81,235,417 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,510,488 - 73,511,537 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1973,657,469 - 73,658,519 (-)NCBI
Celera973,345,732 - 73,346,781 (-)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cxcr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2905
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.