Gene: Cxcr1 (C-X-C motif chemokine receptor 1) Rattus norvegicus
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Symbol: Cxcr1
Name: C-X-C motif chemokine receptor 1
Description: ENCODES a protein that exhibits interleukin-8 binding (ortholog); interleukin-8 receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); receptor internalization (ortholog); ASSOCIATED WITH membranoproliferative glomerulonephritis; acquired immunodeficiency syndrome (ortholog); end stage renal failure (ortholog); FOUND IN integral component of membrane (inferred); INTERACTS WITH ammonium chloride; benzamide; bisphenol A
AGR Description: Predicted to have several functions, including chemokine binding activity and transmembrane signaling receptor activity; predicted to be involved in several processes, including calcium-mediated signaling, cell surface receptor signaling pathway, and immune response; predicted to localize to the external side of plasma membrane; biomarker of membranoproliferative glomerulonephritis; orthologous to human CXCR1 (C-X-C motif chemokine receptor 1).
Merged Description: Predicted to have several functions, including chemokine binding activity and transmembrane signaling receptor activity; predicted to be involved in several processes, including calcium-mediated signaling, cell surface receptor signaling pathway, and immune response; predicted to localize to the external side of plasma membrane; biomarker of membranoproliferative glomerulonephritis; orthologous to human CXCR1 (C-X-C motif chemokine receptor 1); INTERACTS WITH ammonium chloride; benzamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-X-C chemokine receptor type 1; chemokine (C-X-C motif) receptor 1; CXC-R1; CXCR-1; high affinity interleukin-8 receptor A; IL-8R A; Il8ra; interleukin 8 receptor, alpha
Orthologs:
Homo sapiens (human) : CXCR1 (C-X-C motif chemokine receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Cxcr1 (chemokine (C-X-C motif) receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cxcr1 (C-X-C motif chemokine receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CXCR1 (C-X-C motif chemokine receptor 1)
Canis lupus familiaris (dog) : CXCR1 (chemokine (C-X-C motif) receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cxcr1 (C-X-C motif chemokine receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0981,466,430 - 81,469,299 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0981,232,019 - 81,235,417 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,510,488 - 73,511,537 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1973,657,469 - 73,658,519 (-)NCBI
Celera973,345,732 - 73,346,781 (-)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cxcr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2905
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.