Ptprn (protein tyrosine phosphatase, receptor type, N)

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Gene: Ptprn (protein tyrosine phosphatase, receptor type, N) Rattus norvegicus

Analyze

Symbol:

Ptprn

Name:

protein tyrosine phosphatase, receptor type, N

RGD ID:

620777

Description:

Enables GTPase binding activity. Involved in several processes, including positive regulation of type B pancreatic cell proliferation; response to estrogen; and response to insulin. Located in axon terminus; neuronal cell body; and secretory granule. Colocalizes with Golgi apparatus; endosome; and plasma membrane. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human PTPRN (protein tyrosine phosphatase receptor type N); PARTICIPATES IN type 1 diabetes mellitus pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

105 kDa islet cell antigen; BEM-3; brain-enriched membrane-associated protein tyrosine phosphatase; Ia-2; ICA105; ICA512; PTP IA-2; PTPLP; R-PTP-N; receptor-type tyrosine-protein phosphatase-like N

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	76,741,010 - 76,756,704 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	76,741,016 - 76,756,190 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	85,186,238 - 85,200,876 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	90,315,132 - 90,329,764 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	88,701,350 - 88,715,978 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	82,446,626 - 82,462,314 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	82,446,633 - 82,461,903 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	82,215,889 - 82,231,560 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	74,528,095 - 74,542,756 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	74,675,076 - 74,689,738 (-)	NCBI
Celera	9	74,311,913 - 74,326,515 (-)	NCBI		Celera
Cytogenetic Map	9	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alacrima, achalasia, and impaired intellectual development syndrome (ISO)

cerebrotendinous xanthomatosis (ISO)

distal spinal muscular atrophy type 5 (ISO)

Experimental Diabetes Mellitus (ISO)

genetic disease (ISO)

myofibrillar myopathy 1 (ISO)

Neurodevelopmental Disorders (ISO)

paroxysmal nonkinesigenic dyskinesia 1 (ISO)

polydactyly (ISO)

type 1 diabetes mellitus (IDA,ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

amiodarone (ISO)

amitrole (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

arsenite(3-) (ISO)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP)

bisphenol F (EXP)

Butylbenzyl phthalate (EXP)

cadmium dichloride (EXP)

calcitriol (ISO)

chlorpyrifos (ISO)

choline (ISO)

dibutyl phthalate (EXP)

diethyl phthalate (EXP)

diisobutyl phthalate (EXP)

diisononyl phthalate (EXP)

dioxygen (EXP)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

finasteride (EXP)

fipronil (EXP)

folic acid (ISO)

furan (EXP)

genistein (EXP)

gentamycin (EXP)

irinotecan (ISO)

ketamine (EXP)

L-methionine (ISO)

lead diacetate (EXP)

lead(0) (ISO)

leflunomide (EXP)

methimazole (EXP)

methoxychlor (EXP)

miconazole (EXP)

microcystin-LR (ISO)

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (ISO)

N-methyl-4-phenylpyridinium (EXP,ISO)

orphenadrine (EXP)

paracetamol (EXP)

paraquat (EXP)

perfluorooctane-1-sulfonic acid (ISO)

pravastatin (EXP,ISO)

propanal (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (EXP)

serpentine asbestos (ISO)

sodium arsenite (ISO)

Soman (EXP)

sulindac (EXP)

sunitinib (ISO)

tamibarotene (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

tributylstannane (EXP)

trichloroethene (EXP)

triptonide (ISO)

valdecoxib (EXP)

valproic acid (EXP,ISO)

WIN 55212-2 (ISO)

zaragozic acid A (EXP,ISO)

zinc atom (ISO)

zinc sulfate (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytokine-mediated signaling pathway (IDA)

dense core granule maturation (IEA,ISO)

dephosphorylation (IEA)

insulin secretion (IEA,ISO)

insulin secretion involved in cellular response to glucose stimulus (IBA,ISO,ISS)

luteinization (ISO,ISS)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of type B pancreatic cell proliferation (IEA,IMP,ISO)

regulation of secretion (IBA)

response to cAMP (IEP)

response to estrogen (IEP)

response to glucose (IEP)

response to insulin (IEP)

response to reactive oxygen species (IEA,ISO,ISS)

second-messenger-mediated signaling (TAS)

Cellular Component

axon terminus (IDA)

endosome (IDA)

Golgi apparatus (IDA)

neuronal cell body (IDA)

nucleus (IEA,ISO)

perikaryon (IEA)

plasma membrane (IDA)

secretory granule (IBA,IDA,IEA)

synapse (IBA,IDA,IEA)

synaptic vesicle (IDA)

transport vesicle membrane (IEA)

Molecular Function

GTPase binding (IPI)

protein binding (ISO)

protein tyrosine phosphatase activity (IEA,ISO,ISS)

spectrin binding (IEA,ISO)

ubiquitin-like protein ligase binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

type 1 diabetes mellitus pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Receptor-type PTP-NP inhibition of Dynamin-1 GTPase activity is associated with neuronal depolarization.	Jiang S, etal., Cell Signal. 2006 Sep;18(9):1439-46. Epub 2006 Jan 18.
4.	Stabilization of the receptor protein tyrosine phosphatase-like protein ICA512 in GH4C1 cells upon treatment with estradiol, insulin, and epidermal growth factor.	Lee MS, etal., Endocrinology. 1998 Jun;139(6):2727-33.
5.	Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life.	Lobner K, etal., Diabetes. 2002 Oct;51(10):2982-8.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs.	Mziaut H, etal., Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):674-9. doi: 10.1073/pnas.0710931105. Epub 2008 Jan 4.
8.	Insulinoma-associated protein 2-deficient mice develop severe forms of diabetes induced by multiple low doses of streptozotocin.	Nakajima K, etal., Int J Mol Med. 2009 Jul;24(1):23-7.
9.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
10.	Pancreatic Islet Autoantibodies as Predictors of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1).	Orban T, etal., Diabetes Care. 2009 Sep 9.
11.	The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells.	Ort T, etal., Eur J Cell Biol. 2000 Sep;79(9):621-30.
12.	The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.	Passini N, etal., Proc Natl Acad Sci U S A 1995 Sep 26;92(20):9412-6.
13.	Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).	Payton MA, etal., J Clin Invest 1995 Sep;96(3):1506-11.
14.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
15.	GOA pipeline	RGD automated data pipeline
16.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
18.	Comprehensive gene review and curation	RGD comprehensive gene curation
19.	ICA 512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granules.	Solimena M, etal., EMBO J. 1996 May 1;15(9):2102-14.
20.	Effect of proinflammatory cytokines on gene expression of the diabetes-associated autoantigen IA-2 in INS-1 cells.	Steinbrenner H, etal., Endocrinology 2002 Oct;143(10):3839-45.

Additional References at PubMed

PMID:7887886	PMID:8878556	PMID:11086001	PMID:12031972	PMID:15596545	PMID:16269463	PMID:16622421	PMID:18048354	PMID:21732083	PMID:23087044	PMID:24843546	PMID:25561468
PMID:30053369	PMID:30979722

Genomics

Comparative Map Data

Ptprn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	76,741,010 - 76,756,704 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	76,741,016 - 76,756,190 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	85,186,238 - 85,200,876 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	90,315,132 - 90,329,764 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	88,701,350 - 88,715,978 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	82,446,626 - 82,462,314 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	82,446,633 - 82,461,903 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	82,215,889 - 82,231,560 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	74,528,095 - 74,542,756 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	74,675,076 - 74,689,738 (-)	NCBI
Celera	9	74,311,913 - 74,326,515 (-)	NCBI		Celera
Cytogenetic Map	9	q33	NCBI

PTPRN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	219,289,623 - 219,309,401 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	219,289,623 - 219,309,648 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	220,154,345 - 220,174,123 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	219,862,589 - 219,882,387 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	219,979,851 - 219,999,648	NCBI
Celera	2	213,924,192 - 213,944,148 (-)	NCBI		Celera
Cytogenetic Map	2	q35	NCBI
HuRef	2	212,007,432 - 212,027,331 (-)	NCBI		HuRef
CHM1_1	2	220,160,193 - 220,180,139 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	219,774,379 - 219,794,153 (-)	NCBI		T2T-CHM13v2.0

Ptprn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	75,223,679 - 75,241,437 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	75,223,671 - 75,241,146 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	75,247,035 - 75,264,497 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	75,247,027 - 75,264,502 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	75,243,616 - 75,260,783 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	75,130,189 - 75,147,297 (-)	NCBI		MGSCv36	mm8
Celera	1	75,737,937 - 75,755,020 (-)	NCBI		Celera
Cytogenetic Map	1	C4	NCBI
cM Map	1	38.64	NCBI

Ptprn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	14,126,416 - 14,145,347 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	14,126,416 - 14,145,347 (+)	NCBI	ChiLan1.0	ChiLan1.0

PTPRN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	2B	121,934,995 - 121,954,893 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	106,547,156 - 106,567,056 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	225,138,283 - 225,158,118 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	225,138,887 - 225,206,700 (-)	Ensembl	panpan1.1		panPan2

PTPRN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	25,835,590 - 25,854,050 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	25,836,118 - 25,869,931 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	26,661,448 - 26,679,881 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	25,850,814 - 25,869,258 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	25,849,713 - 25,869,231 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	25,755,175 - 25,773,586 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	25,690,528 - 25,708,945 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	25,711,218 - 25,729,647 (-)	NCBI		UU_Cfam_GSD_1.0

Ptprn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	175,355,937 - 175,374,833 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936569	1,696,059 - 1,717,744 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936569	1,698,718 - 1,717,639 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PTPRN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	121,329,287 - 121,349,168 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	121,329,284 - 121,349,228 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	134,364,686 - 134,384,609 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PTPRN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	105,196,508 - 105,216,665 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	105,196,505 - 105,216,525 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	94,181,166 - 94,200,998 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ptprn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624823	5,710,622 - 5,729,093 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624823	5,710,669 - 5,734,739 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ptprn
104 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	88
Count of miRNA genes:	71
Interacting mature miRNAs:	80
Transcripts:	ENSRNOT00000026654
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	22071169	86369743	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	23754144	83851531	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	25268044	79271759	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	32535505	77535505	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	32535505	77535505	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	36962359	77814038	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	40194188	85194188	Rat
11353949	Bp393	Blood pressure QTL 393			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	40194188	85194188	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	42495343	79271511	Rat
10058949	Gmadr5	Adrenal mass QTL 5	2	0.014	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	9	42791513	87976209	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	55847841	77026453	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	56627713	78595166	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	9	56627713	78595166	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56627713	78595166	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	62072275	96470995	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	62072275	96470995	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
1581517	Bp284	Blood pressure QTL 284			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	76650629	76771824	Rat

Markers in Region

D9Mco68

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,742,351 - 76,742,539 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,447,968 - 82,448,155	NCBI	Rnor6.0
Rnor_5.0	9	82,217,229 - 82,217,416	UniSTS	Rnor5.0
RGSC_v3.4	9	74,528,930 - 74,529,117	UniSTS	RGSC3.4
Celera	9	74,312,748 - 74,312,935	UniSTS
Cytogenetic Map	9	q33	UniSTS

D9Mco44

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,757,822 - 76,758,010 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,463,433 - 82,463,620	NCBI	Rnor6.0
Rnor_5.0	9	82,232,694 - 82,232,881	UniSTS	Rnor5.0
RGSC_v3.4	9	74,544,448 - 74,544,635	UniSTS	RGSC3.4
Celera	9	74,328,207 - 74,328,394	UniSTS
Cytogenetic Map	9	q33	UniSTS

RH131806

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,741,156 - 76,741,349 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,446,773 - 82,446,965	NCBI	Rnor6.0
Rnor_5.0	9	82,216,034 - 82,216,226	UniSTS	Rnor5.0
RGSC_v3.4	9	74,527,735 - 74,527,927	UniSTS	RGSC3.4
Celera	9	74,311,553 - 74,311,745	UniSTS
Cytogenetic Map	9	q33	UniSTS

X74438

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,741,016 - 76,741,112 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,446,633 - 82,446,728	NCBI	Rnor6.0
Rnor_5.0	9	82,215,894 - 82,215,989	UniSTS	Rnor5.0
RGSC_v3.4	9	74,527,595 - 74,527,690	UniSTS	RGSC3.4
Celera	9	74,311,413 - 74,311,508	UniSTS
Cytogenetic Map	9	q33	UniSTS

MARC_8095-8096:996688286:1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,745,650 - 76,746,337 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,451,265 - 82,451,951	NCBI	Rnor6.0
Rnor_5.0	9	82,220,526 - 82,221,212	UniSTS	Rnor5.0
RGSC_v3.4	9	74,532,227 - 74,532,913	UniSTS	RGSC3.4
Celera	9	74,316,045 - 74,316,731	UniSTS
Cytogenetic Map	9	q33	UniSTS

PTPRN_1350

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,741,022 - 76,741,590 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,446,639 - 82,447,206	NCBI	Rnor6.0
Rnor_5.0	9	82,215,900 - 82,216,467	UniSTS	Rnor5.0
RGSC_v3.4	9	74,527,601 - 74,528,168	UniSTS	RGSC3.4
Celera	9	74,311,419 - 74,311,986	UniSTS
Cytogenetic Map	9	q33	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			4	2		2			72	13	4
Low	3	32	45	31	11	31	3	3	2	22	37	9	3
Below cutoff		11	8	8	8	8	5	7				2	5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D45414	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U40652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000026654 ⟹ ENSRNOP00000026654

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	76,741,016 - 76,756,190 (-)	Ensembl
Rnor_6.0 Ensembl	9	82,446,633 - 82,461,903 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094318 ⟹ ENSRNOP00000081951

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	76,741,016 - 76,755,174 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000111188 ⟹ ENSRNOP00000088497

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	76,741,019 - 76,756,177 (-)	Ensembl

RefSeq Acc Id:

NM_053881 ⟹ NP_446333

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	76,741,014 - 76,756,163 (-)	NCBI
Rnor_6.0	9	82,447,133 - 82,461,741 (-)	NCBI
Rnor_5.0	9	82,215,889 - 82,231,560 (-)	NCBI
RGSC_v3.4	9	74,528,095 - 74,542,756 (-)	RGD
Celera	9	74,311,913 - 74,326,515 (-)	RGD

Sequence:

show sequence

ATGAGGCGCCCGCGGCGGCCCGGAGGTCCCGCGGGCTGCGGGGGCTCCGAGGGTTCCGGGGGCC
TTCGGCTGCTGGTCTGCCTGCTGTTGTTGAGCGGCCGCCCCGGGGGCTGCAGCGCCATCAGTGC
CCACGGCTGTCTCTTTGACCGCAGACTTTGTTCGCATCTGGAAGTCTGTATTCAGGATGGCTTG
TTTGGACAGTGCCAGGCAGGAGTGGGGCAGGCACGGCCCCTCTTACAAGTCACTTCCCCAGTTC
TCCAGCGCTTACAAGGTGTGCTCCGGCAACTCATGTCCCAAGGCTTGTCCTGGCATGATGACCT
CACCCAGTATGTGATCTCCCAGGAGATGGAACGAATCCCCAGGCTTCGTCCCCCAGAACCTCAT
CCAAGGGACAGATCTGGATCGGTGCCCAGGAGAGCAGGCCCAGCAGGGGAATTGCTTTCTCAGG
GCAATCCCACTGGCTCCTCTCCTGCTGTCCAGGGGCTCTCTCGGCCTCCAGGGGATGGGAATGG
AGCTGGGGTGGGCTCCCCACTGTCCTCTCTGCAGGCTGAGCTGTTACCCCCTCTCTTGGAGCAT
CTGCTAATGCCCCCGCAGCCTCCACACCCGTCTCTGACCTATGAACCTGCATTGCTACAACCTT
ACTTGTTCCAGCAGTTTGGTTCCCGAGATGGCTCCCGGGGCTCAGAGAGCGCCTCTGGGGTAGT
TGGCCATCTGGCCAAGGCTGAAGATCCTGTACTCTTCAGCAGAAGCCTCTCCAAGGCCATTTTG
GGGACTCACTCTGGACACTCCTTTGGTGACCTTACAGGTCCCTCACCTGCTCAGCTTTTCCAGG
ATTCAGGGCTGCTCTACATGGCCCAAGAGTTGCCAGTGCCTGGCAGAGCCCGGGCGCCAAGGTT
GCCAGAGGAAGGGGGCAGCAGCCGGGCAGAGGACTCTTCAGAGGGCCATGAGGAGGAAGTACTA
GGGGGTCATGGGGAGAAGTCCCCTCCCCAAGCAGTACAAGCAGATGTAAGTCTGCAGAGATTGG
CTGCTGTGCTGGCAGGCTACGGAGTAGAGCTGCGTCAGCTGACCCCGGAACAGCTTTCTACCCT
CTTAACCCTGCTGCAGTTACTGCCCAAGGGCACAGGAAGACATCTTGGAGGGGCTGTGAACGGA
GGAGCCGATGTCAAGAAAACAATAGAAGAACAAATGCAGAGAGGGGACACAGCAGACGCTCGGC
CCCCCACACCCTTGCTTCCTGGACACCCCACTGCCAGCTCCACCTCCATCAAAGTTCGGCAGGT
GCTGAGCCCTGGTTTCCCTGAACCTCCCAAGACATCCAGTCCTCTGGGCATCTCGGCTGTCCTG
CTGGAGAAGAAAAGTCCCTTGGGCCAGAGCCAGCCCACAGTGGTGGGACAGCCTTCAGCTCGAC
CGTCCGCTGAGGAGTATGGCTATATAGTCACTGATCAGAAACCCCTGAGTCTGGTGGCTGGAGT
GAAGTTGCTGGAGATCCTGGCTGAACATGTGCACATGACTTCAGGCAGCTTCATCAACATCAGT
GTGGTAGGACCAGCTGTCACCTTCCGAATCCGGCACAATGAGCAGAACTTGTCTTTGGCAGATG
TGACCCAGCAAGCTGGGCTGGTGAAGTCTGAACTGGAAGCGCAGACAGGGCTCCAGATTTTGCA
GACAGGGGTGGGACAGAGGGAGGAATCCGCCGCAGTCCTTCCCCGACAAGCCCATGGCATATCT
CCCATGCGCTCATTGCTGCTTACTCTGGTGGCCCTGGCAGGTGTCGCTGGGCTACTAGTAGCTT
TGGCGGTGGCCCTGTGTATGCGCCATCATTCGAAACAACGGGATAAGGAGCGCCTGGCCGCGCT
GGGGCCGGAGGGGGCCCACGGTGACACTACTTTTGAATACCAGGACCTGTGTCGCCAGCACATG
GCCACAAAGTCGCTGTTTAACCGGGCAGAGGGTCAGCCAGAGCCTTCTCGGGTGAGCAGTGTGT
CCTCCCAGTTCAGTGACGCGGCCCAGGCCAGCCCCAGTTCCCACAGCAGCACACCGTCCTGGTG
CGAGGAGCCTGCCCAGGCCAACATGGACATCTCCACAGGACACATGATTCTGGCATACATGGAG
GATCACCTCCGGAACCGGGACCGGTTGGCCAAGAAGTGGCAGGCCCTGTGCGCCTACCAAGCGG
AGCCAAACACCTGTGCCACCGCACAAGGTGAAGGCAACATCAAGAAGAACCGCCATCCTGACTT
CTTACCCTATGACCATGCCCGAATCAAGCTGAAAGTGGAGAGCAGCCCCTCTCGGAGTGATTAC
ATCAACGCCAGTCCCATCATCGAGCATGACCCTCGGATGCCGGCCTACATAGCCACACAGGGAC
CCCTGTCCCACACCATCGCAGACTTCTGGCAGATGGTGTGGGAGAGTGGCTGCACTGTCATCGT
TATGCTGACCCCTTTGGTGGAGGATGGTGTCAAACAGTGTGACCGCTACTGGCCGGATGAAGGG
TCCTCCCTCTACCACGTCTATGAGGTGAACCTGGTGTCTGAGCACATCTGGTGCGAGGACTTCC
TGGTGCGGAGCTTCTACCTGAAGAACGTGCAGACCCAGGAGACGCGCACGCTCACTCAGTTCCA
CTTCCTCAGCTGGCCGGCAGAGGGCACTCCGGCCTCCACCCGGCCGCTGCTGGACTTCCGCAGG
AAAGTGAACAAGTGCTACAGAGGCCGCTCCTGTCCCATCATAGTGCACTGCAGTGATGGTGCAG
GGAGGACAGGCACCTACATCCTTATTGACATGGTACTGAATCGCATGGCGAAAGGAGTGAAGGA
GATTGATATCGCTGCCACCCTGGAGCATGTCCGTGACCAGCGACCTGGCCTTGTCCGTTCTAAG
GACCAGTTTGAGTTTGCGCTGACAGCCGTGGCGGAGGAGGTGAATGCCATCCTCAAGGCCCTGC
CCCAGTGA

hide sequence

RefSeq Acc Id:

XM_006245134 ⟹ XP_006245196

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	76,741,023 - 76,756,215 (-)	NCBI
Rnor_6.0	9	82,446,626 - 82,461,822 (-)	NCBI
Rnor_5.0	9	82,215,889 - 82,231,560 (-)	NCBI

Sequence:

show sequence

ACTCCGCCTAGGCTCCTGGGTTGACTCCCACCAACGTCGCTGAGACTCTGGCCGGAGAGCGAGA
GCTCAGAGCCGGGAAGGATGAGGCGCCCGCGGCGGCCCGGAGGTCCCGCGGGCTGCGGGGGCTC
CGAGGGTTCCGGGGGCCTTCGGCTGCTGGTCTGCCTGCTGTTGTTGAGCGGCCGCCCCGGGGGC
TGCAGCGCCATCAGTGCCCACGGCTGTCTCTTTGACCGCAGACTTTGTTCGCATCTGGAAGTCT
GTATTCAGGATGGCTTGTTTGGACAGTGCCAGGCAGGAGTGGGGCAGGCACGGCCCCTCTTACA
AGTCACTTCCCCAGTTCTCCAGCGCTTACAAGGTGTGCTCCGGCAACTCATGTCCCAAGGCTTG
TCCTGGCATGATGACCTCACCCAGTATGTGATCTCCCAGGAGATGGAACGAATCCCCAGGCTTC
GTCCCCCAGAACCTCATCCAAGGGACAGATCTGGATCGGTGCCCAGGAGAGCAGGCCCAGCAGG
GGAATTGCTTTCTCAGGGCAATCCCACTGGCTCCTCTCCTGCTGTCCAGGGGCTCTCTCGGCCT
CCAGGGGATGGGAATGGAGCTGGGGTGGGCTCCCCACTGTCCTCTCTGCAGGCTGAGCTGTTAC
CCCCTCTCTTGGAGCATCTGCTAATGCCCCCGCAGCCTCCACACCCGTCTCTGACCTATGAACC
TGCATTGCTACAACCTTACTTGTTCCAGCAGTTTGGTTCCCGAGATGGCTCCCGGGGCTCAGAG
AGCGCCTCTGGGGTAGTTGGCCATCTGGCCAAGGCTGAAGATCCTGTACTCTTCAGCAGAAGCC
TCTCCAAGGCCATTTTGGGGACTCACTCTGGACACTCCTTTGGTGACCTTACAGGTCCCTCACC
TGCTCAGCTTTTCCAGGATTCAGGGCTGCTCTACATGGCCCAAGAGTTGCCAGTGCCTGGCAGA
GCCCGGGCGCCAAGGTTGCCAGAGGAAGGGGGCAGCAGCCGGGCAGAGGACTCTTCAGAGGGCC
ATGAGGAGGAAGTACTAGGGGGTCATGGGGAGAAGTCCCCTCCCCAAGCAGTACAAGCAGCAGA
TGTAAGTCTGCAGAGATTGGCTGCTGTGCTGGCAGGCTACGGAGTAGAGCTGCGTCAGCTGACC
CCGGAACAGCTTTCTACCCTCTTAACCCTGCTGCAGTTACTGCCCAAGGGCACAGGAAGACATC
TTGGAGGGGCTGTGAACGGAGGAGCCGATGTCAAGAAAACAATAGAAGAACAAATGCAGAGAGG
GGACACAGCAGACGCTCGGCCCCCCACACCCTTGCTTCCTGGACACCCCACTGCCAGCTCCACC
TCCATCAAAGTTCGGCAGGTGCTGAGCCCTGGTTTCCCTGAACCTCCCAAGACATCCAGTCCTC
TGGGCATCTCGGCTGTCCTGCTGGAGAAGAAAAGTCCCTTGGGCCAGAGCCAGCCCACAGTGGT
GGGACAGCCTTCAGCTCGACCGTCCGCTGAGGAGTATGGCTATATAGTCACTGATCAGAAACCC
CTGAGTCTGGTGGCTGGAGTGAAGTTGCTGGAGATCCTGGCTGAACATGTGCACATGACTTCAG
GCAGCTTCATCAACATCAGTGTGGTAGGACCAGCTGTCACCTTCCGAATCCGGCACAATGAGCA
GAACTTGTCTTTGGCAGATGTGACCCAGCAAGCTGGGCTGGTGAAGTCTGAACTGGAAGCGCAG
ACAGGGCTCCAGATTTTGCAGACAGGGGTGGGACAGAGGGAGGAATCCGCCGCAGTCCTTCCCC
GACAAGCCCATGGCATATCTCCCATGCGCTCATTGCTGCTTACTCTGGTGGCCCTGGCAGGTGT
CGCTGGGCTACTAGTAGCTTTGGCGGTGGCCCTGTGTATGCGCCATCATTCGAAACAACGGGAT
AAGGAGCGCCTGGCCGCGCTGGGGCCGGAGGGGGCCCACGGTGACACTACTTTTGAATACCAGG
ACCTGTGTCGCCAGCACATGGCCACAAAGTCGCTGTTTAACCGGGCAGAGGGTCAGCCAGAGCC
TTCTCGGGTGAGCAGTGTGTCCTCCCAGTTCAGTGACGCGGCCCAGGCCAGCCCCAGTTCCCAC
AGCAGCACACCGTCCTGGTGCGAGGAGCCTGCCCAGGCCAACATGGACATCTCCACAGGACACA
TGATTCTGGCATACATGGAGGATCACCTCCGGAACCGGGACCGGTTGGCCAAGGAGTGGCAGGC
CCTGTGCGCCTACCAAGCGGAGCCAAACACCTGTGCCACCGCACAAGGTGAAGGCAACATCAAG
AAGAACCGCCATCCTGACTTCTTACCCTATGACCATGCCCGAATCAAGCTGAAAGTGGAGAGCA
GCCCCTCTCGGAGTGATTACATCAACGCCAGTCCCATCATCGAGCATGACCCTCGGATGCCGGC
CTACATAGCCACACAGGGACCCCTGTCCCACACCATCGCAGACTTCTGGCAGATGGTGTGGGAG
AGTGGCTGCACTGTCATCGTTATGCTGACCCCTTTGGTGGAGGATGGTGTCAAACAGTGTGACC
GCTACTGGCCGGATGAAGGGTCCTCCCTCTACCACGTCTATGAGGTGAACCTGGTGTCTGAGCA
CATCTGGTGCGAGGACTTCCTGGTGCGGAGCTTCTACCTGAAGAACGTGCAGACCCAGGAGACG
CGCACGCTCACTCAGTTCCACTTCCTCAGCTGGCCGGCAGAGGGCACTCCGGCCTCCACCCGGC
CGCTGCTGGACTTCCGCAGGAAAGTGAACAAGTGCTACAGAGGCCGCTCCTGTCCCATCATAGT
GCACTGCAGTGATGGTGCAGGGAGGACAGGCACCTACATCCTTATTGACATGGTACTGAATCGC
ATGGCGAAAGGAGTGAAGGAGATTGATATCGCTGCCACCCTGGAGCATGTCCGTGACCAGCGAC
CTGGCCTTGTCCGTTCTAAGGACCAGTTTGAGTTTGCGCTGACAGCCGTGGCGGAGGAGGTGAA
TGCCATCCTCAAGGCCCTGCCCCAGTGAGCCCCCTGGGTACCTCAGTGGGCATCCTGGCCTCTG
CTCCTTCTGCCTGTGTGTGAGCATTTGTGCACCCACTCTTCAGCCCCTACCCATCTGCCACCTT
GGTCCGTCCGACTTGGGCATGATAGCCCTTTCCAACCCAGTGTGGAAGGAAGTCGGGAGGGAAG
GGGCAGGTCCACCCTGCTTTATTCACGCTAGAACCAAGATCTCCTGTGGGAAACAGACAGCAGG
CAAGGGGAGGAGTGGACACCAGCAGCAAGTGTGCCCGAGCCCCATCCTTCCTGAGTCTCTGTCT
CCCTCTGTGTGTGTACCTCCCCACTCCCACCAGCCTATCGTGTATAGACAAAGCAGAATGAGAA
GGCCCCAGCTCCCCCCAGTCCTGCTACCACTGGCCTGCCACCTTGACCCTGCTCAACCTTCTCC
CTCTAGCACAAGCAAACATTTCTAGAAAAATCTACTTTTGTATCAATGTGAATAAAGTTAGTGT
GTTGTCTGTGCAGCTGCAACATG

hide sequence

RefSeq Acc Id:

XM_017596229 ⟹ XP_017451718

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	76,741,010 - 76,756,704 (-)	NCBI
Rnor_6.0	9	82,446,626 - 82,462,314 (-)	NCBI

Sequence:

show sequence

CACCTTGTAGGGCAGATGCTTTCTTGCCCCTTCAGACAAGAGTACGCAACTAACTCAAGGCTAT
CCCAGCGAGAGTGCCTAGCCATCTCTGATTTTCGGGATGACGCCAGTAGTGAACTTGAGTCCTT
CTTACCAAACCTGAGCCAGGGTGGCAGAGGCAGTGGACCTGAAGAATACAGGTCAGGAGTGGGT
GGACCCAGTGGGAATTCTAGGGAGGAACCTACTATTTGGTGGAGGAGGCTTAGGTTGAGTAGCT
CCCCGGCTGAGAGGGGGCTCTTACGCCAGTATGACGCAAATAGGCCTAAGAGCCGGGGGTGGAG
ATGTCGTCATTGCACGCCTGCAGTTGGCCGGGTCGCCTCAAGAGGGGCAAGTAGACCCCGCCTT
GGAGGCTGTCTCTTTGACCGCAGACTTTGTTCGCATCTGGAAGTCTGTATTCAGGATGGCTTGT
TTGGACAGTGCCAGGCAGGAGTGGGGCAGGCACGGCCCCTCTTACAAGTCACTTCCCCAGTTCT
CCAGCGCTTACAAGGTGTGCTCCGGCAACTCATGTCCCAAGGCTTGTCCTGGCATGATGACCTC
ACCCAGTATGTGATCTCCCAGGAGATGGAACGAATCCCCAGGCTTCGTCCCCCAGAACCTCATC
CAAGGGACAGATCTGGATCGGTGCCCAGGAGAGCAGGCCCAGCAGGGGAATTGCTTTCTCAGGG
CAATCCCACTGGCTCCTCTCCTGCTGTCCAGGGGCTCTCTCGGCCTCCAGGGGATGGGAATGGA
GCTGGGGTGGGCTCCCCACTGTCCTCTCTGCAGGCTGAGCTGTTACCCCCTCTCTTGGAGCATC
TGCTAATGCCCCCGCAGCCTCCACACCCGTCTCTGACCTATGAACCTGCATTGCTACAACCTTA
CTTGTTCCAGCAGTTTGGTTCCCGAGATGGCTCCCGGGGCTCAGAGAGCGCCTCTGGGGTAGTT
GGCCATCTGGCCAAGGCTGAAGATCCTGTACTCTTCAGCAGAAGCCTCTCCAAGGCCATTTTGG
GGACTCACTCTGGACACTCCTTTGGTGACCTTACAGGTCCCTCACCTGCTCAGCTTTTCCAGGA
TTCAGGGCTGCTCTACATGGCCCAAGAGTTGCCAGTGCCTGGCAGAGCCCGGGCGCCAAGGTTG
CCAGAGGAAGGGGGCAGCAGCCGGGCAGAGGACTCTTCAGAGGGCCATGAGGAGGAAGTACTAG
GGGGTCATGGGGAGAAGTCCCCTCCCCAAGCAGTACAAGCAGCAGATGTAAGTCTGCAGAGATT
GGCTGCTGTGCTGGCAGGCTACGGAGTAGAGCTGCGTCAGCTGACCCCGGAACAGCTTTCTACC
CTCTTAACCCTGCTGCAGTTACTGCCCAAGGGCACAGGAAGACATCTTGGAGGGGCTGTGAACG
GAGGAGCCGATGTCAAGAAAACAATAGAAGAACAAATGCAGAGAGGGGACACAGCAGACGCTCG
GCCCCCCACACCCTTGCTTCCTGGACACCCCACTGCCAGCTCCACCTCCATCAAAGTTCGGCAG
GTGCTGAGCCCTGGTTTCCCTGAACCTCCCAAGACATCCAGTCCTCTGGGCATCTCGGCTGTCC
TGCTGGAGAAGAAAAGTCCCTTGGGCCAGAGCCAGCCCACAGTGGTGGGACAGCCTTCAGCTCG
ACCGTCCGCTGAGGAGTATGGCTATATAGTCACTGATCAGAAACCCCTGAGTCTGGTGGCTGGA
GTGAAGTTGCTGGAGATCCTGGCTGAACATGTGCACATGACTTCAGGCAGCTTCATCAACATCA
GTGTGGTAGGACCAGCTGTCACCTTCCGAATCCGGCACAATGAGCAGAACTTGTCTTTGGCAGA
TGTGACCCAGCAAGCTGGGCTGGTGAAGTCTGAACTGGAAGCGCAGACAGGGCTCCAGATTTTG
CAGACAGGGGTGGGACAGAGGGAGGAATCCGCCGCAGTCCTTCCCCGACAAGCCCATGGCATAT
CTCCCATGCGCTCATTGCTGCTTACTCTGGTGGCCCTGGCAGGTGTCGCTGGGCTACTAGTAGC
TTTGGCGGTGGCCCTGTGTATGCGCCATCATTCGAAACAACGGGATAAGGAGCGCCTGGCCGCG
CTGGGGCCGGAGGGGGCCCACGGTGACACTACTTTTGAATACCAGGACCTGTGTCGCCAGCACA
TGGCCACAAAGTCGCTGTTTAACCGGGCAGAGGGTCAGCCAGAGCCTTCTCGGGTGAGCAGTGT
GTCCTCCCAGTTCAGTGACGCGGCCCAGGCCAGCCCCAGTTCCCACAGCAGCACACCGTCCTGG
TGCGAGGAGCCTGCCCAGGCCAACATGGACATCTCCACAGGACACATGATTCTGGCATACATGG
AGGATCACCTCCGGAACCGGGACCGGTTGGCCAAGGAGTGGCAGGCCCTGTGCGCCTACCAAGC
GGAGCCAAACACCTGTGCCACCGCACAAGGTGAAGGCAACATCAAGAAGAACCGCCATCCTGAC
TTCTTACCCTATGACCATGCCCGAATCAAGCTGAAAGTGGAGAGCAGCCCCTCTCGGAGTGATT
ACATCAACGCCAGTCCCATCATCGAGCATGACCCTCGGATGCCGGCCTACATAGCCACACAGGG
ACCCCTGTCCCACACCATCGCAGACTTCTGGCAGATGGTGTGGGAGAGTGGCTGCACTGTCATC
GTTATGCTGACCCCTTTGGTGGAGGATGGTGTCAAACAGTGTGACCGCTACTGGCCGGATGAAG
GGTCCTCCCTCTACCACGTCTATGAGGTGAACCTGGTGTCTGAGCACATCTGGTGCGAGGACTT
CCTGGTGCGGAGCTTCTACCTGAAGAACGTGCAGACCCAGGAGACGCGCACGCTCACTCAGTTC
CACTTCCTCAGCTGGCCGGCAGAGGGCACTCCGGCCTCCACCCGGCCGCTGCTGGACTTCCGCA
GGAAAGTGAACAAGTGCTACAGAGGCCGCTCCTGTCCCATCATAGTGCACTGCAGTGATGGTGC
AGGGAGGACAGGCACCTACATCCTTATTGACATGGTACTGAATCGCATGGCGAAAGGAGTGAAG
GAGATTGATATCGCTGCCACCCTGGAGCATGTCCGTGACCAGCGACCTGGCCTTGTCCGTTCTA
AGGACCAGTTTGAGTTTGCGCTGACAGCCGTGGCGGAGGAGGTGAATGCCATCCTCAAGGCCCT
GCCCCAGTGAGCCCCCTGGGTACCTCAGTGGGCATCCTGGCCTCTGCTCCTTCTGCCTGTGTGT
GAGCATTTGTGCACCCACTCTTCAGCCCCTACCCATCTGCCACCTTGGTCCGTCCGACTTGGGC
ATGATAGCCCTTTCCAACCCAGTGTGGAAGGAAGTCGGGAGGGAAGGGGCAGGTCCACCCTGCT
TTATTCACGCTAGAACCAAGATCTCCTGTGGGAAACAGACAGCAGGCAAGGGGAGGAGTGGACA
CCAGCAGCAAGTGTGCCCGAGCCCCATCCTTCCTGAGTCTCTGTCTCCCTCTGTGTGTGTACCT
CCCCACTCCCACCAGCCTATCGTGTATAGACAAAGCAGAATGAGAAGGCCCCAGCTCCCCCCAG
TCCTGCTACCACTGGCCTGCCACCTTGACCCTGCTCAACCTTCTCCCTCTAGCACAAGCAAACA
TTTCTAGAAAAATCTACTTTTGTATCAATGTGAATAAAGTTAGTGTGTTGTCTGTGCAGCTGCA
ACATG

hide sequence

RefSeq Acc Id:

XM_017596230 ⟹ XP_017451719

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	76,741,023 - 76,756,704 (-)	NCBI
Rnor_6.0	9	82,446,626 - 82,462,314 (-)	NCBI

Sequence:

show sequence

CACCTTGTAGGGCAGATGCTTTCTTGCCCCTTCAGACAAGAGTACGCAACTAACTCAAGGCTAT
CCCAGCGAGAGTGCCTAGCCATCTCTGATTTTCGGGATGACGCCAGTAGTGAACTTGAGTCCTT
CTTACCAAACCTGAGCCAGGGTGGCAGAGGCAGTGGACCTGAAGAATACAGGTCAGGAGTGGGT
GGACCCAGTGGGAATTCTAGGGAGGAACCTACTATTTGGTGGAGGAGGCTTAGGTTGAGTAGCT
CCCCGGCTGAGAGGGGGCTCTTACGCCAGTATGACGCAAATAGGCCTAAGAGCCGGGGGTGGAG
ATGTCGTCATTGCACGCCTGCAGTTGGCCGGGTCGCCTCAAGAGGGGCAAGTAGACCCCGCCTT
GGAGGCTGTCTCTTTGACCGCAGACTTTGTTCGCATCTGGAAGTCTGTATTCAGGATGGCTTGT
TTGGACAGTGCCAGGCAGGAGTGGGGCAGGCACGGCCCCTCTTACAAGTCACTTCCCCAGTTCT
CCAGCGCTTACAAGGTGTGCTCCGGCAACTCATGTCCCAAGGCTTGTCCTGGCATGATGACCTC
ACCCAGTATGTGATCTCCCAGGAGATGGAACGAATCCCCAGGCTTCGTCCCCCAGAACCTCATC
CAAGGGACAGATCTGGATCGGTGCCCAGGAGAGCAGGCCCAGCAGGGGAATTGCTTTCTCAGGG
CAATCCCACTGGCTCCTCTCCTGCTGTCCAGGGGCTCTCTCGGCCTCCAGGGGATGGGAATGGA
GCTGGGGTGGGCTCCCCACTGTCCTCTCTGCAGGCTGAGCTGTTACCCCCTCTCTTGGAGCATC
TGCTAATGCCCCCGCAGCCTCCACACCCGTCTCTGACCTATGAACCTGCATTGCTACAACCTTA
CTTGTTCCAGCAGTTTGGTTCCCGAGATGGCTCCCGGGGCTCAGAGAGCGCCTCTGGGGTAGTT
GGCCATCTGGCCAAGGCTGAAGATCCTGTACTCTTCAGCAGAAGCCTCTCCAAGGCCATTTTGG
GGACTCACTCTGGACACTCCTTTGGTGACCTTACAGGTCCCTCACCTGCTCAGCTTTTCCAGGA
TTCAGGGCTGCTCTACATGGCCCAAGAGTTGCCAGTGCCTGGCAGAGCCCGGGCGCCAAGGTTG
CCAGAGGAAGGGGGCAGCAGCCGGGCAGAGGACTCTTCAGAGGGCCATGAGGAGGAAGTACTAG
GGGGTCATGGGGAGAAGTCCCCTCCCCAAGCAGTACAAGCAGATGTAAGTCTGCAGAGATTGGC
TGCTGTGCTGGCAGGCTACGGAGTAGAGCTGCGTCAGCTGACCCCGGAACAGCTTTCTACCCTC
TTAACCCTGCTGCAGTTACTGCCCAAGGGCACAGGAAGACATCTTGGAGGGGCTGTGAACGGAG
GAGCCGATGTCAAGAAAACAATAGAAGAACAAATGCAGAGAGGGGACACAGCAGACGCTCGGCC
CCCCACACCCTTGCTTCCTGGACACCCCACTGCCAGCTCCACCTCCATCAAAGTTCGGCAGGTG
CTGAGCCCTGGTTTCCCTGAACCTCCCAAGACATCCAGTCCTCTGGGCATCTCGGCTGTCCTGC
TGGAGAAGAAAAGTCCCTTGGGCCAGAGCCAGCCCACAGTGGTGGGACAGCCTTCAGCTCGACC
GTCCGCTGAGGAGTATGGCTATATAGTCACTGATCAGAAACCCCTGAGTCTGGTGGCTGGAGTG
AAGTTGCTGGAGATCCTGGCTGAACATGTGCACATGACTTCAGGCAGCTTCATCAACATCAGTG
TGGTAGGACCAGCTGTCACCTTCCGAATCCGGCACAATGAGCAGAACTTGTCTTTGGCAGATGT
GACCCAGCAAGCTGGGCTGGTGAAGTCTGAACTGGAAGCGCAGACAGGGCTCCAGATTTTGCAG
ACAGGGGTGGGACAGAGGGAGGAATCCGCCGCAGTCCTTCCCCGACAAGCCCATGGCATATCTC
CCATGCGCTCATTGCTGCTTACTCTGGTGGCCCTGGCAGGTGTCGCTGGGCTACTAGTAGCTTT
GGCGGTGGCCCTGTGTATGCGCCATCATTCGAAACAACGGGATAAGGAGCGCCTGGCCGCGCTG
GGGCCGGAGGGGGCCCACGGTGACACTACTTTTGAATACCAGGACCTGTGTCGCCAGCACATGG
CCACAAAGTCGCTGTTTAACCGGGCAGAGGGTCAGCCAGAGCCTTCTCGGGTGAGCAGTGTGTC
CTCCCAGTTCAGTGACGCGGCCCAGGCCAGCCCCAGTTCCCACAGCAGCACACCGTCCTGGTGC
GAGGAGCCTGCCCAGGCCAACATGGACATCTCCACAGGACACATGATTCTGGCATACATGGAGG
ATCACCTCCGGAACCGGGACCGGTTGGCCAAGGAGTGGCAGGCCCTGTGCGCCTACCAAGCGGA
GCCAAACACCTGTGCCACCGCACAAGGTGAAGGCAACATCAAGAAGAACCGCCATCCTGACTTC
TTACCCTATGACCATGCCCGAATCAAGCTGAAAGTGGAGAGCAGCCCCTCTCGGAGTGATTACA
TCAACGCCAGTCCCATCATCGAGCATGACCCTCGGATGCCGGCCTACATAGCCACACAGGGACC
CCTGTCCCACACCATCGCAGACTTCTGGCAGATGGTGTGGGAGAGTGGCTGCACTGTCATCGTT
ATGCTGACCCCTTTGGTGGAGGATGGTGTCAAACAGTGTGACCGCTACTGGCCGGATGAAGGGT
CCTCCCTCTACCACGTCTATGAGGTGAACCTGGTGTCTGAGCACATCTGGTGCGAGGACTTCCT
GGTGCGGAGCTTCTACCTGAAGAACGTGCAGACCCAGGAGACGCGCACGCTCACTCAGTTCCAC
TTCCTCAGCTGGCCGGCAGAGGGCACTCCGGCCTCCACCCGGCCGCTGCTGGACTTCCGCAGGA
AAGTGAACAAGTGCTACAGAGGCCGCTCCTGTCCCATCATAGTGCACTGCAGTGATGGTGCAGG
GAGGACAGGCACCTACATCCTTATTGACATGGTACTGAATCGCATGGCGAAAGGAGTGAAGGAG
ATTGATATCGCTGCCACCCTGGAGCATGTCCGTGACCAGCGACCTGGCCTTGTCCGTTCTAAGG
ACCAGTTTGAGTTTGCGCTGACAGCCGTGGCGGAGGAGGTGAATGCCATCCTCAAGGCCCTGCC
CCAGTGAGCCCCCTGGGTACCTCAGTGGGCATCCTGGCCTCTGCTCCTTCTGCCTGTGTGTGAG
CATTTGTGCACCCACTCTTCAGCCCCTACCCATCTGCCACCTTGGTCCGTCCGACTTGGGCATG
ATAGCCCTTTCCAACCCAGTGTGGAAGGAAGTCGGGAGGGAAGGGGCAGGTCCACCCTGCTTTA
TTCACGCTAGAACCAAGATCTCCTGTGGGAAACAGACAGCAGGCAAGGGGAGGAGTGGACACCA
GCAGCAAGTGTGCCCGAGCCCCATCCTTCCTGAGTCTCTGTCTCCCTCTGTGTGTGTACCTCCC
CACTCCCACCAGCCTATCGTGTATAGACAAAGCAGAATGAGAAGGCCCCAGCTCCCCCCAGTCC
TGCTACCACTGGCCTGCCACCTTGACCCTGCTCAACCTTCTCCCTCTAGCACAAGCAAACATTT
CTAGAAAAATCTACTTTTGTATCAATGTGAATAAAGTTAGTGTGTTGTCTGTGCAGCTGCAACA
TG

hide sequence

RefSeq Acc Id:

XM_039082907 ⟹ XP_038938835

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	76,741,023 - 76,755,830 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_446333	(Get FASTA)	NCBI Sequence Viewer
	XP_006245196	(Get FASTA)	NCBI Sequence Viewer
	XP_017451718	(Get FASTA)	NCBI Sequence Viewer
	XP_017451719	(Get FASTA)	NCBI Sequence Viewer
	XP_038938835	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA83235	(Get FASTA)	NCBI Sequence Viewer
	BAA08254	(Get FASTA)	NCBI Sequence Viewer
	CAA63313	(Get FASTA)	NCBI Sequence Viewer
	EDL75420	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000026654
	ENSRNOP00000026654.5
	ENSRNOP00000081951.1
	ENSRNOP00000088497
	ENSRNOP00000088497.1
GenBank Protein	Q63259	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_446333 ⟸ NM_053881
- Peptide Label:	precursor
- UniProtKB:	Q63795 (UniProtKB/Swiss-Prot), Q63259 (UniProtKB/Swiss-Prot), Q62883 (UniProtKB/Swiss-Prot), Q64643 (UniProtKB/Swiss-Prot), A6JW12 (UniProtKB/TrEMBL), A0A8I6A9W6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRRPRRPGGPAGCGGSEGSGGLRLLVCLLLLSGRPGGCSAISAHGCLFDRRLCSHLEVCIQDGL FGQCQAGVGQARPLLQVTSPVLQRLQGVLRQLMSQGLSWHDDLTQYVISQEMERIPRLRPPEPH PRDRSGSVPRRAGPAGELLSQGNPTGSSPAVQGLSRPPGDGNGAGVGSPLSSLQAELLPPLLEH LLMPPQPPHPSLTYEPALLQPYLFQQFGSRDGSRGSESASGVVGHLAKAEDPVLFSRSLSKAIL GTHSGHSFGDLTGPSPAQLFQDSGLLYMAQELPVPGRARAPRLPEEGGSSRAEDSSEGHEEEVL GGHGEKSPPQAVQADVSLQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLLPKGTGRHLGGAVNG GADVKKTIEEQMQRGDTADARPPTPLLPGHPTASSTSIKVRQVLSPGFPEPPKTSSPLGISAVL LEKKSPLGQSQPTVVGQPSARPSAEEYGYIVTDQKPLSLVAGVKLLEILAEHVHMTSGSFINIS VVGPAVTFRIRHNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVGQREESAAVLPRQAHGIS PMRSLLLTLVALAGVAGLLVALAVALCMRHHSKQRDKERLAALGPEGAHGDTTFEYQDLCRQHM ATKSLFNRAEGQPEPSRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYME DHLRNRDRLAKKWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDY INASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEG SSLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRR KVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSK DQFEFALTAVAEEVNAILKALPQ hide sequence

RefSeq Acc Id:	XP_006245196 ⟸ XM_006245134
- Peptide Label:	isoform X3
- UniProtKB:	A0A8L2QEF0 (UniProtKB/TrEMBL), A0A8I6A9W6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRRPRRPGGPAGCGGSEGSGGLRLLVCLLLLSGRPGGCSAISAHGCLFDRRLCSHLEVCIQDGL FGQCQAGVGQARPLLQVTSPVLQRLQGVLRQLMSQGLSWHDDLTQYVISQEMERIPRLRPPEPH PRDRSGSVPRRAGPAGELLSQGNPTGSSPAVQGLSRPPGDGNGAGVGSPLSSLQAELLPPLLEH LLMPPQPPHPSLTYEPALLQPYLFQQFGSRDGSRGSESASGVVGHLAKAEDPVLFSRSLSKAIL GTHSGHSFGDLTGPSPAQLFQDSGLLYMAQELPVPGRARAPRLPEEGGSSRAEDSSEGHEEEVL GGHGEKSPPQAVQAADVSLQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLLPKGTGRHLGGAVN GGADVKKTIEEQMQRGDTADARPPTPLLPGHPTASSTSIKVRQVLSPGFPEPPKTSSPLGISAV LLEKKSPLGQSQPTVVGQPSARPSAEEYGYIVTDQKPLSLVAGVKLLEILAEHVHMTSGSFINI SVVGPAVTFRIRHNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVGQREESAAVLPRQAHGI SPMRSLLLTLVALAGVAGLLVALAVALCMRHHSKQRDKERLAALGPEGAHGDTTFEYQDLCRQH MATKSLFNRAEGQPEPSRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYM EDHLRNRDRLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSD YINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDE GSSLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFR RKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRS KDQFEFALTAVAEEVNAILKALPQ hide sequence

RefSeq Acc Id:	XP_017451719 ⟸ XM_017596230
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZW92 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSCPFRQEYATNSRLSQRECLAISDFRDDASSELESFLPNLSQGGRGSGPEEYRSGVGGPSGN SREEPTIWWRRLRLSSSPAERGLLRQYDANRPKSRGWRCRHCTPAVGRVASRGASRPRLGGCLF DRRLCSHLEVCIQDGLFGQCQAGVGQARPLLQVTSPVLQRLQGVLRQLMSQGLSWHDDLTQYVI SQEMERIPRLRPPEPHPRDRSGSVPRRAGPAGELLSQGNPTGSSPAVQGLSRPPGDGNGAGVGS PLSSLQAELLPPLLEHLLMPPQPPHPSLTYEPALLQPYLFQQFGSRDGSRGSESASGVVGHLAK AEDPVLFSRSLSKAILGTHSGHSFGDLTGPSPAQLFQDSGLLYMAQELPVPGRARAPRLPEEGG SSRAEDSSEGHEEEVLGGHGEKSPPQAVQADVSLQRLAAVLAGYGVELRQLTPEQLSTLLTLLQ LLPKGTGRHLGGAVNGGADVKKTIEEQMQRGDTADARPPTPLLPGHPTASSTSIKVRQVLSPGF PEPPKTSSPLGISAVLLEKKSPLGQSQPTVVGQPSARPSAEEYGYIVTDQKPLSLVAGVKLLEI LAEHVHMTSGSFINISVVGPAVTFRIRHNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVGQ REESAAVLPRQAHGISPMRSLLLTLVALAGVAGLLVALAVALCMRHHSKQRDKERLAALGPEGA HGDTTFEYQDLCRQHMATKSLFNRAEGQPEPSRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQ ANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDH ARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPL VEDGVKQCDRYWPDEGSSLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWP AEGTPASTRPLLDFRRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAA TLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ hide sequence

RefSeq Acc Id:	XP_017451718 ⟸ XM_017596229
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZW92 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSCPFRQEYATNSRLSQRECLAISDFRDDASSELESFLPNLSQGGRGSGPEEYRSGVGGPSGN SREEPTIWWRRLRLSSSPAERGLLRQYDANRPKSRGWRCRHCTPAVGRVASRGASRPRLGGCLF DRRLCSHLEVCIQDGLFGQCQAGVGQARPLLQVTSPVLQRLQGVLRQLMSQGLSWHDDLTQYVI SQEMERIPRLRPPEPHPRDRSGSVPRRAGPAGELLSQGNPTGSSPAVQGLSRPPGDGNGAGVGS PLSSLQAELLPPLLEHLLMPPQPPHPSLTYEPALLQPYLFQQFGSRDGSRGSESASGVVGHLAK AEDPVLFSRSLSKAILGTHSGHSFGDLTGPSPAQLFQDSGLLYMAQELPVPGRARAPRLPEEGG SSRAEDSSEGHEEEVLGGHGEKSPPQAVQAADVSLQRLAAVLAGYGVELRQLTPEQLSTLLTLL QLLPKGTGRHLGGAVNGGADVKKTIEEQMQRGDTADARPPTPLLPGHPTASSTSIKVRQVLSPG FPEPPKTSSPLGISAVLLEKKSPLGQSQPTVVGQPSARPSAEEYGYIVTDQKPLSLVAGVKLLE ILAEHVHMTSGSFINISVVGPAVTFRIRHNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVG QREESAAVLPRQAHGISPMRSLLLTLVALAGVAGLLVALAVALCMRHHSKQRDKERLAALGPEG AHGDTTFEYQDLCRQHMATKSLFNRAEGQPEPSRVSSVSSQFSDAAQASPSSHSSTPSWCEEPA QANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYD HARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTP LVEDGVKQCDRYWPDEGSSLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSW PAEGTPASTRPLLDFRRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIA ATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ hide sequence

RefSeq Acc Id:

ENSRNOP00000026654 ⟸ ENSRNOT00000026654

RefSeq Acc Id:	XP_038938835 ⟸ XM_039082907
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I5ZW92 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000088497 ⟸ ENSRNOT00000111188

RefSeq Acc Id:

ENSRNOP00000081951 ⟸ ENSRNOT00000094318

Protein Domains

Tyrosine specific protein phosphatases Tyrosine-protein phosphatase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q63259-F1-model_v2	AlphaFold	Q63259	1-983	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696777

Promoter ID:

EPDNEW_R7301

Type:

initiation region

Name:

Ptprn_1

Description:

protein tyrosine phosphatase, receptor type, N

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	82,461,769 - 82,461,829	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620777	AgrOrtholog
BioCyc Gene	G2FUF-27085	BioCyc
Ensembl Genes	ENSRNOG00000019587	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000026654	ENTREZGENE
	ENSRNOT00000026654.7	UniProtKB/TrEMBL
	ENSRNOT00000094318.1	UniProtKB/TrEMBL
	ENSRNOT00000111188	ENTREZGENE
	ENSRNOT00000111188.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.2470	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.90.190.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	IA-2/IA-2_beta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot-tyrosine_phosphatase-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTP_cat	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
	Receptor_IA-2_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Receptor_IA-2_ectodomain_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RESP18_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_Pase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_Pase_cat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_Pase_dom	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
KEGG Report	rno:116660	UniProtKB/Swiss-Prot
NCBI Gene	116660	ENTREZGENE
PANTHER	PTHR46106	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE-LIKE N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Receptor_IA-2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RESP18	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Y_phosphatase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ptprn	PhenoGen
PRINTS	PRTYPHPHTASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	TYR_PHOSPHATASE_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TYR_PHOSPHATASE_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TYR_PHOSPHATASE_PTP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000019587	RatGTEx
SMART	PTPc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTPc_motif	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RESP18	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF52799	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5ZW92	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A9W6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2QEF0	ENTREZGENE, UniProtKB/TrEMBL
	A6JW12	ENTREZGENE, UniProtKB/TrEMBL
	PTPRN_RAT	UniProtKB/Swiss-Prot
	Q62883	ENTREZGENE
	Q63259	ENTREZGENE
	Q63795	ENTREZGENE
	Q64643	ENTREZGENE
UniProt Secondary	Q62883	UniProtKB/Swiss-Prot
	Q63795	UniProtKB/Swiss-Prot
	Q64643	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Ptprn	protein tyrosine phosphatase, receptor type, N			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Ptprn	protein tyrosine phosphatase, receptor type, N			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_disease	autoantibodies to the cytoplasmic domain occur in 55{75% of newly diagnosed patients with type 1 diabetes	628454
gene_expression	expressed in neurons and in pancreatic islets	628454
gene_physical_interaction	binds to beta2-syntrophin and neuronal nitric oxide synthase	628454
gene_process	connects the secretory granules with the actin cytoskeleton and the nitric oxide signaling pathways in beta-cells	628454
gene_process	may regulate the beta- cell function	628454
gene_product	member of the protein tyrosine phosphatase family	628454
gene_product	membrane protein of the secretory vesicles	628454
gene_regulation	expression is inhibited by IL-1b, TNF-alpha, and IFN-gamma	628454

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)