Orc2 (origin recognition complex, subunit 2)

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Gene: Orc2 (origin recognition complex, subunit 2) Rattus norvegicus

Analyze

Symbol:

Orc2

Name:

origin recognition complex, subunit 2

RGD ID:

1311844

Description:

Predicted to enable DNA replication origin binding activity. Predicted to be involved in DNA replication. Predicted to be located in centrosome and nucleoplasm. Predicted to be part of heterochromatin; inner kinetochore; and nuclear origin of replication recognition complex. Predicted to colocalize with chromosome, telomeric region. Orthologous to human ORC2 (origin recognition complex subunit 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC301430; Orc2l; origin recognition complex subunit 2; origin recognition complex, subunit 2-like; origin recognition complex, subunit 2-like (S. cerevisiae); origin recognition complex, subunit 2-like (yeast)

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ORC2 (origin recognition complex subunit 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Orc2 (origin recognition complex, subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Orc2 (origin recognition complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ORC2 (origin recognition complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ORC2 (origin recognition complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Orc2 (origin recognition complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ORC2 (origin recognition complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ORC2 (origin recognition complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Orc2 (origin recognition complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NRIP3 (nuclear receptor interacting protein 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ORC2 (origin recognition complex subunit 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Orc2 (origin recognition complex, subunit 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	orc2 (origin recognition complex, subunit 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ORC2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Orc2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	orc-2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	orc2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	60,001,631 - 60,038,301 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	60,001,910 - 60,038,195 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	68,497,057 - 68,526,891 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	9	73,612,987 - 73,642,822 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	9	71,931,062 - 71,960,894 (-)	NCBI	Rnor_WKY
Rnor_6.0	9	65,350,630 - 65,387,293 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	65,350,627 - 65,387,169 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	65,157,924 - 65,194,576 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	57,125,684 - 57,155,508 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	57,272,665 - 57,302,490 (-)	NCBI
Celera	9	57,445,799 - 57,475,616 (-)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Pulmonary Arterial Hypertension (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

(S)-nicotine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

2-amino-2-deoxy-D-glucopyranose (ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

4-nitrophenol (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucosamine (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

atrazine (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-D-glucosamine (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

coumarin (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

formaldehyde (ISO)

glafenine (EXP)

Heptachlor epoxide (ISO)

indometacin (ISO)

methyl methanesulfonate (ISO)

nicotine (ISO)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (ISO)

progesterone (ISO)

quercetin (ISO)

resveratrol (ISO)

sunitinib (ISO)

tamibarotene (ISO)

thapsigargin (ISO)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA replication (IEA)

Cellular Component

centrosome (ISO)

chromatin (ISO)

chromosome, telomeric region (ISO)

heterochromatin (ISO)

inner kinetochore (ISO)

nuclear origin of replication recognition complex (IBA,IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (ISO)

origin recognition complex (ISO)

Molecular Function

DNA replication origin binding (IBA,IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:12941272	PMID:14519686	PMID:15215892	PMID:15983387	PMID:15998811	PMID:17716973	PMID:19135898	PMID:19946888	PMID:20932478	PMID:21029866	PMID:21383955
PMID:24270157

Genomics

Comparative Map Data

Orc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	60,001,631 - 60,038,301 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	60,001,910 - 60,038,195 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	68,497,057 - 68,526,891 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	9	73,612,987 - 73,642,822 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	9	71,931,062 - 71,960,894 (-)	NCBI	Rnor_WKY
Rnor_6.0	9	65,350,630 - 65,387,293 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	65,350,627 - 65,387,169 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	65,157,924 - 65,194,576 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	57,125,684 - 57,155,508 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	57,272,665 - 57,302,490 (-)	NCBI
Celera	9	57,445,799 - 57,475,616 (-)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

ORC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	200,908,977 - 200,963,660 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	2	200,908,977 - 200,963,680 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	201,773,700 - 201,828,383 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	201,483,139 - 201,536,655 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	201,600,400 - 201,653,916	NCBI
Celera	2	195,529,524 - 195,583,050 (-)	NCBI		Celera
Cytogenetic Map	2	q33.1	NCBI
HuRef	2	193,626,266 - 193,679,712 (-)	NCBI		HuRef
CHM1_1	2	201,780,893 - 201,834,423 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	201,392,427 - 201,447,106 (-)	NCBI		T2T-CHM13v2.0

Orc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	58,501,930 - 58,544,268 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	58,501,930 - 58,544,268 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	58,462,771 - 58,505,113 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	58,462,771 - 58,505,109 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	58,519,615 - 58,561,763 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	58,407,317 - 58,449,465 (-)	NCBI		MGSCv36	mm8
Celera	1	58,981,002 - 59,022,881 (-)	NCBI		Celera
Cytogenetic Map	1	C1.3	NCBI

Orc2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	577,955 - 628,068 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	576,268 - 628,068 (+)	NCBI	ChiLan1.0	ChiLan1.0

ORC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	2B	103,550,709 - 103,615,470 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	88,166,351 - 88,221,618 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	206,325,661 - 206,380,874 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	206,325,661 - 206,380,647 (-)	Ensembl	panpan1.1		panPan2

ORC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	10,109,825 - 10,155,588 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	10,111,496 - 10,151,876 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	10,995,051 - 11,040,792 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	10,015,322 - 10,061,228 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	10,015,322 - 10,061,310 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	9,996,794 - 10,042,534 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	9,974,603 - 10,020,315 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	9,968,534 - 10,014,278 (-)	NCBI		UU_Cfam_GSD_1.0

Orc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	158,244,624 - 158,288,326 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936726	211,859 - 255,754 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936726	215,483 - 259,867 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ORC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	104,613,610 - 104,656,492 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	104,612,727 - 104,656,558 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	115,941,048 - 115,954,008 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ORC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	86,567,350 - 86,629,693 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	86,564,332 - 86,629,855 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	112,790,444 - 112,851,284 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Orc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624889	227,510 - 268,784 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624889	224,658 - 269,815 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Orc2
71 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	109
Count of miRNA genes:	92
Interacting mature miRNAs:	101
Transcripts:	ENSRNOT00000051843
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
631680	Cm11	Cardiac mass QTL 11	3.1	0.00089	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	9	20430519	65430519	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	22071169	86369743	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	22071200	67071200	Rat
1300180	Bw14	Body weight QTL 14	3.776		body mass (VT:0001259)	body weight (CMO:0000012)	9	23754024	61381613	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	23754144	83851531	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	25268044	79271759	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	27468639	72468639	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	32535505	77535505	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	32535505	77535505	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	36962359	77814038	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	40194188	85194188	Rat
11353949	Bp393	Blood pressure QTL 393			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	40194188	85194188	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	42495343	79271511	Rat
10058949	Gmadr5	Adrenal mass QTL 5	2	0.014	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	9	42791513	87976209	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
1598849	Memor17	Memory QTL 17	2.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	49968546	71098346	Rat
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	55847841	77026453	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	56627713	78595166	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	9	56627713	78595166	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56627713	78595166	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	28	40	24	19	24	1	1	74	35	41	11	1
Low		15	17	17		17	7	10					7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006244956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596359	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083305	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB164704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC123462	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC129076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000051843 ⟹ ENSRNOP00000042867

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	60,001,910 - 60,038,195 (-)	Ensembl
Rnor_6.0 Ensembl	9	65,350,627 - 65,387,169 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099033 ⟹ ENSRNOP00000079927

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	60,001,910 - 60,031,971 (-)	Ensembl

RefSeq Acc Id:

NM_001012003 ⟹ NP_001012003

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	60,002,638 - 60,032,467 (-)	NCBI
Rnor_6.0	9	65,351,635 - 65,381,459 (-)	NCBI
Rnor_5.0	9	65,157,924 - 65,194,576 (-)	NCBI
RGSC_v3.4	9	57,125,684 - 57,155,508 (-)	RGD
Celera	9	57,445,799 - 57,475,616 (-)	RGD

Sequence:

show sequence

AGTTACAGGTGACTGGATGGTCAAGCCGCAGAATGCCTAGCACCTTACAAGGTTGGCCACAATG
AGCACACTGCGGTTAAAGGAAGCCAAGGTGCCAAGCGTTCAGTTTGTGGGAGATGACGATGTTC
TTAGTCACATTCTGGATAGAGAAGGAGGAACTAAATTAAAGAAGGAGAAAGTTCAGCTTTTGGT
CAATCCCCAGAAAGTAATAAAGAAGGCAGAATGTGAATTAGAGAAAAGTGACCTGGAAGTCTTA
GAGGATCAGAACTACGTGGAAGTCTTGGGAAGAAATATTCAAGAATCCTTGGGAAATGGCTCTG
CTGTAGATGGTAGGAATAAAGTTTATTCTTTTCAACACAGAAAACACCCTGAAGAGATGACTAA
ATTGGCTTTAGAACTGGCAAAAACATCAGGAAAAATTGATCCACTTGCCTCAAACGATCCTAAA
ATCACGAAAAACATTGCTCGAAAAAGCAAAGGGCATTCTTCAGAGAAAGCTCCGCTGGAGAACA
ATAACAAAAATGAATTTCCGTCAATACAACCTCATAATGTAAGAAAAAGATTAATAGCATCAAG
GTCTCATTGTGACAGTGAAAGTGAATATTCTGCTTCCAGCTCAGAAGATGATGAAGAGGTTGCA
AAAGACGATGAAGAAGACACTAATGTGGTCAGGTGCTCGAAAAAGAGTCAAGGTCAGAATAGAC
TACTTCCAGCTCCTGTTTCCAAAGAGATACTGCCCAAGAAAAGGAAGAGAGACAAAGCAGGTGA
CTTGGTAGAAGAATATTTTGAAGCCCACAGTAGTTCAAAAGTCTTAACGTCTGATAGAACGCTG
CAGAAGCTGAGGAGAGCGAGAGTGGACCAGAAAACTCTGCGTAACTTACTGAGCAAATTTGTGC
CTTCCTTTTCTACTGAAATTGGACAGTTGAATCAACAGCATGAGAGATTGTTTGATAAGTGGAT
ACTACAGTTACGCCTTGGGTTCAACATTGTGCTTTATGGTTTGGGGTCTAAGAGAGATTTACTA
GAAAAGTTTCGAACTACCATGCTTCAAGATTCCATTCATGTTGTCATCAACGGCTTCTTTCCTG
GCATCAGTGTAAAATCAATCCTGAACTCTATAACTGAAGATGTCCTCAGTCACATGGGTACTTT
CCAAAGTGTTCTGGATCAGCGAGACTGGATAATGAACAGATTTAAAGAAGATTCTTCTTTAGAA
CTCTTTCTTCTTATCCACAATTTGGATAGCCAGATGTTAAGAGGAGACAATAGCCAGCAAATTC
TTGGACAGTTGTCATCCTTACGTAATGTGTATCTCATAGCATCTATCGACCACCTCAATGCTCC
TCTCATGTGGGATCATGCAAAGCAGAGTCTGTACAATTGGCTGTGGTATGAAACCACTACATAC
AGTCCTTACACCGAAGAAACCTCCTATGAGAACTCCCTTTTGGTTAAACAGTCTGGATCTCTAC
CACTGAGTTCTCTGATTCATGTCTTACGAAGCCTTACACCCAATGCAAGGGGGATTTTCAGGCT
ACTTATGAAGTACCAACTGGATAACCAGGACTGCCCTTCCTACATTGGACTTTCTTTTCAAGAT
TTTTACCAGCAGTGTCGGGAAGCATTCCTTGTTAACAGTGATCTCACACTCCGAGCCCAGTTAA
CTGAATTTAGGGACCACAAACTTATAAGAACGAAGAAGGGAACTGATGGTGTGGAGTATTTATT
AATTCCTGTTGACAGCGGAACATTGGCCGATTTCTTGGAGAAGGAGGAGGAGGAGGAGTCGTAG
ACTGTCTCTTACCCTTGAACCTTATGTGG

hide sequence

RefSeq Acc Id:

XM_006244956 ⟹ XP_006245018

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	60,001,631 - 60,038,300 (-)	NCBI
Rnor_6.0	9	65,350,630 - 65,387,293 (-)	NCBI
Rnor_5.0	9	65,157,924 - 65,194,576 (-)	NCBI

Sequence:

show sequence

TTTTCCGACTGAGCTAAGTCCTTTTGGCCCGAGTCAACGGGCTTGGGGCGCCGTCGCTCTTGGC
GACTCGGCTCCCCATTGGTCTCTTAGGGCACCGCCCACGGGCGGGCGAGGGATTCGGTGTGCTG
CGCGCAGTTCCATTACCCTGCTGGGGCTCCGAGGTTCGGCTTGTGCCAGTCGATATTTTCCTGG
ACGCCGGCCTCCCCAGGCCGTTCTGGGGTTTCCCGCGCCGGCTGGAGTCCTGGCTGGCCGCGCG
TGTGAGCCTCGCGGCCGTTCTTCCTTCCGCCGGCTCTGACTCAAGAGTTACAGGTGACTGGATG
GTCAAGCCGCAGAATGCCTAGCACCTTACAAGGTTGGCCACAATGAGCACACTGCGGTTAAAGG
AAGCCAAGGTGCCAAGCGTTCAGTTTGTGGGAGATGACGATGTTCTTAGTCACATTCTGGATAG
AGAAGGAGGAACTAAATTAAAGAAGGAGAAAGTTCAGCTTTTGGTCAATCCCCAGAAAGTAATA
AAGAAGGCAGAATGTGAATTAGAGAAAAGTGACCTGGAAGTCTTAGAGGATCAGAACTACGTGG
AAGTCTTGGGAAGAAATATTCAAGAATCCTTGGGAAATGGCTCTGCTGTAGATGGTAGGAATAA
AGTTTATTCTTTTCAACACAGAAAACACCCTGAAGAGATGACTAAATTGGCTTTAGAACTGGCA
AAAACATCAGGAAAAATTGATCCACTTGCCTCAAACGATCCTAAAATCACGAAAAACATTGCTC
GAAAAAGCAAAGGGCATTCTTCAGAGAAAGCTCCGCTGGAGAACAATAACAAAAATGAATTTCC
GTCAATACAACCTCATAATGTAAGAAAAAGATTAATAGCATCAAGGTCTCATTGTGACAGTGAA
AGTGAATATTCTGCTTCCAGCTCAGAAGATGATGAAGAGGTTGCAAAAGACGATGAAGAAGACA
CTAATGTGGTCAGGTGCTCGAAAAAGAGTCAAGGTCAGAATAGACTACTTCCAGCTCCTGTTTC
CAAAGAGATACTGCCCAAGAAAAGGAAGAGAGACAAAGCAGGTGACTTGGTAGAAGAATATTTT
GAAGCCCACAGTAGTTCAAAAGTCTTAACGTCTGATAGAACGCTGCAGAAGCTGAGGAGAGCGA
GAGTGGACCAGAAAACTCTGCGTAACTTACTGAGCAAATTTGTGCCTTCCTTTTCTACTGAAAT
TGGACAGTTGAATCAACAGCATGAGAGATTGTTTGATAAGTGGATACTACAGTTACGCCTTGGG
TTCAACATTGTGCTTTATGGTTTGGGGTCTAAGAGAGATTTACTAGAAAAGTTTCGAACTACCA
TGCTTCAAGATTCCATTCATGTTGTCATCAACGGCTTCTTTCCTGGCATCAGTGTAAAATCAAT
CCTGAACTCTATAACTGAAGATGTCCTCAGTCACATGGGTACTTTCCAAAGTGTTCTGGATCAG
CGAGACTGGATAATGAACAGATTTAAAGAAGATTCTTCTTTAGAACTCTTTCTTCTTATCCACA
ATTTGGATAGCCAGATGTTAAGAGGAGACAATAGCCAGCAAATTCTTGGACAGTTGTCATCCTT
ACGTAATGTGTATCTCATAGCATCTATCGACCACCTCAATGCTCCTCTCATGTGGGATCATGCA
AAGCAGAGTCTGTACAATTGGCTGTGGTATGAAACCACTACATACAGTCCTTACACCGAAGAAA
CCTCCTATGAGAACTCCCTTTTGGTTAAACAGTCTGGATCTCTACCACTGAGTTCTCTGATTCA
TGTCTTACGAAGCCTTACACCCAATGCAAGGGGGATTTTCAGGCTACTTATGAAGTACCAACTG
GATAACCAGGACTGCCCTTCCTACATTGGACTTTCTTTTCAAGATTTTTACCAGCAGTGTCGGG
AAGCATTCCTTGTTAACAGTGATCTCACACTCCGAGCCCAGTTAACTGAATTTAGGGACCACAA
ACTTATAAGAACGAAGAAGGGAACTGATGGTGTGGAGTATTTATTAATTCCTGTTGACAGCGGA
ACATTGGCCGATTTCTTGGAGAAGGAGGAGGAGGAGGAGTCGTAGACTGTCTCTTACCCTTGAA
CCTTATGTGGAAGCCTCGGTGTGCCCCAGCTGCTGCTCCTCTAGTAAGAATGCTGGTTTACATC
CAACATTAGGTCATTCTCTCCAGCATACAAGATGTCCTGTGGAAGAGGCATATCATCAATTTGA
ACTTTGATTAGCCTGGCTGGTGTACAGTCTCGAATACTATGCAGTGGTTGTTGAGTTGGGAAAA
AAAAATGTGCCTTTAATTTATTACCTCTCGGGAGACGTCTTGCTGGTTGAACAGTGCTCAGGGA
TCATTTGGAACTGGTTGTTTTGGATTATTTTATACTGGATGCTATCCCTGTTTTTGAGGGCAAC
ACTCCAGAGCTGAATTGCTACAAGTGCACTTGCTTCAGATCGTCAGAGCACAGAGGTCAGAGTG
CAGGGATCTCGCAGAACTGATAAGGAAGGAGGTGTTCCTTCTGTTCTTGCTGAAGCGATGATGA
AAAGCATCGGTGGACTAGGATGACCCAGCTTTCTCCTGTGGACTTGGGCTACACCTCCTGAAGA
CCGTTGACACTATTCAGCTGAGTTTATGGGAGAAGTGTAAGGGATATATGTGTGTGTAGAGCAT
GTGTCCGATCTAGAAAGCATATTTAAAATAGTTGGTGTCTGTACCAGGACCTTGATTTTTATGA
AACAAATGAGAAGCCAGGCTAAGAAATAAAATCCTAGCTTACATTTTCTCAATTGTTTTCAGGA
CAATAAAGAATAAAAACATTTCATCATCCTTGTACATTGACACTTTTGATTTTCTTAAATAGCT
TGCAGGAATAGGTAGGTAGCACACACCTTTAATCCTAGCGCTCCGGAGTCAGAGGCAGGCAGAT
TGCTTCTCTCCTTTTAAAACAAAACATGAGCTCACATTTGTAATCTCAACATCAAGAGGTAGAG
GCAGGAGGAAAACATGAGTTCAAGACCTGGACTAGTTAGTGAGTTCTAGACCAGCCTAAGCTGC
GGTGACGTCCTGTTTCAATAAAGTAATTTAATAAATAATCACATTGGTAGCACGA

hide sequence

RefSeq Acc Id:

XM_017596360 ⟹ XP_017451849

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	60,001,631 - 60,038,301 (-)	NCBI
Rnor_6.0	9	65,350,630 - 65,387,293 (-)	NCBI

Sequence:

show sequence

TTTTCCGACTGAGCTAAGTCCTTTTGGCCCGAGTCAACGGGCTTGGGGCGCCGTCGCTCTTGGC
GACTCGGCTCCCCATTGGTCTCTTAGGGCACCGCCCACGGGCGGGCGAGGGATTCGGTGTGCTG
CGCGCAGTTCCATTACCCTGCTGGGGCTCCGAGGTTCGGCTTGTGCCAGTCGATATTTTCCTGG
ACGCCGGCCTCCCCAGGCCGTTCTGGGGTTTCCCGCGCCGGCTGGAGTCCTGGCTGGCCGCGCG
TGTGAGCCTCGCGGCCGTTCTTCCTTCCGCCGGCTCTGACTCAAGAGTTACAGGTGACTGGATG
GTCAAGCCGCAGAATGCCTAGCACCTTACAAGGTTGGCCACAATGAGCACACTGCGGTTAAAGG
AAGCCAAGGTGCCAAGCGTTCAGTTTGTGGGAGATGACGATGTTCTTAGTCACATTCTGGATAG
AGAAGGAGGAACTAAATTAAAGAAGGAGAAAGTTCAGCTTTTGGTCAATCCCCAGAAAGTAATA
AAGAAGGCAGAATGTGAATTAGAGAAAAGTGACCTGGAAGTCTTAGAGGATCAGAACTACGTGG
AAGTCTTGGGAAGAAATATTCAAGAATCCTTGGGAAATGGCTCTGCTGTAGATGGTAGGAATAA
AGTTTATTCTTTTCAACACAGAAAACACCCTGAAGAGATGACTAAATTGGCTTTAGAACTGGCA
AAAACATCAGGAAAAATTGATCCACTTGCCTCAAACGATCCTAAAATCACGAAAAACATTGCTC
GAAAAAGCAAAGCATCAAGGTCTCATTGTGACAGTGAAAGTGAATATTCTGCTTCCAGCTCAGA
AGATGATGAAGAGGTTGCAAAAGACGATGAAGAAGACACTAATGTGGTCAGGTGCTCGAAAAAG
AGTCAAGGTCAGAATAGACTACTTCCAGCTCCTGTTTCCAAAGAGATACTGCCCAAGAAAAGGA
AGAGAGACAAAGCAGGTGACTTGGTAGAAGAATATTTTGAAGCCCACAGTAGTTCAAAAGTCTT
AACGTCTGATAGAACGCTGCAGAAGCTGAGGAGAGCGAGAGTGGACCAGAAAACTCTGCGTAAC
TTACTGAGCAAATTTGTGCCTTCCTTTTCTACTGAAATTGGACAGTTGAATCAACAGCATGAGA
GATTGTTTGATAAGTGGATACTACAGTTACGCCTTGGGTTCAACATTGTGCTTTATGGTTTGGG
GTCTAAGAGAGATTTACTAGAAAAGTTTCGAACTACCATGCTTCAAGATTCCATTCATGTTGTC
ATCAACGGCTTCTTTCCTGGCATCAGTGTAAAATCAATCCTGAACTCTATAACTGAAGATGTCC
TCAGTCACATGGGTACTTTCCAAAGTGTTCTGGATCAGCGAGACTGGATAATGAACAGATTTAA
AGAAGATTCTTCTTTAGAACTCTTTCTTCTTATCCACAATTTGGATAGCCAGATGTTAAGAGGA
GACAATAGCCAGCAAATTCTTGGACAGTTGTCATCCTTACGTAATGTGTATCTCATAGCATCTA
TCGACCACCTCAATGCTCCTCTCATGTGGGATCATGCAAAGCAGAGTCTGTACAATTGGCTGTG
GTATGAAACCACTACATACAGTCCTTACACCGAAGAAACCTCCTATGAGAACTCCCTTTTGGTT
AAACAGTCTGGATCTCTACCACTGAGTTCTCTGATTCATGTCTTACGAAGCCTTACACCCAATG
CAAGGGGGATTTTCAGGCTACTTATGAAGTACCAACTGGATAACCAGGACTGCCCTTCCTACAT
TGGACTTTCTTTTCAAGATTTTTACCAGCAGTGTCGGGAAGCATTCCTTGTTAACAGTGATCTC
ACACTCCGAGCCCAGTTAACTGAATTTAGGGACCACAAACTTATAAGAACGAAGAAGGGAACTG
ATGGTGTGGAGTATTTATTAATTCCTGTTGACAGCGGAACATTGGCCGATTTCTTGGAGAAGGA
GGAGGAGGAGGAGTCGTAGACTGTCTCTTACCCTTGAACCTTATGTGGAAGCCTCGGTGTGCCC
CAGCTGCTGCTCCTCTAGTAAGAATGCTGGTTTACATCCAACATTAGGTCATTCTCTCCAGCAT
ACAAGATGTCCTGTGGAAGAGGCATATCATCAATTTGAACTTTGATTAGCCTGGCTGGTGTACA
GTCTCGAATACTATGCAGTGGTTGTTGAGTTGGGAAAAAAAAATGTGCCTTTAATTTATTACCT
CTCGGGAGACGTCTTGCTGGTTGAACAGTGCTCAGGGATCATTTGGAACTGGTTGTTTTGGATT
ATTTTATACTGGATGCTATCCCTGTTTTTGAGGGCAACACTCCAGAGCTGAATTGCTACAAGTG
CACTTGCTTCAGATCGTCAGAGCACAGAGGTCAGAGTGCAGGGATCTCGCAGAACTGATAAGGA
AGGAGGTGTTCCTTCTGTTCTTGCTGAAGCGATGATGAAAAGCATCGGTGGACTAGGATGACCC
AGCTTTCTCCTGTGGACTTGGGCTACACCTCCTGAAGACCGTTGACACTATTCAGCTGAGTTTA
TGGGAGAAGTGTAAGGGATATATGTGTGTGTAGAGCATGTGTCCGATCTAGAAAGCATATTTAA
AATAGTTGGTGTCTGTACCAGGACCTTGATTTTTATGAAACAAATGAGAAGCCAGGCTAAGAAA
TAAAATCCTAGCTTACATTTTCTCAATTGTTTTCAGGACAATAAAGAATAAAAACATTTCATCA
TCCTTGTACATTGACACTTTTGATTTTCTTAAATAGCTTGCAGGAATAGGTAGGTAGCACACAC
CTTTAATCCTAGCGCTCCGGAGTCAGAGGCAGGCAGATTGCTTCTCTCCTTTTAAAACAAAACA
TGAGCTCACATTTGTAATCTCAACATCAAGAGGTAGAGGCAGGAGGAAAACATGAGTTCAAGAC
CTGGACTAGTTAGTGAGTTCTAGACCAGCCTAAGCTGCGGTGACGTCCTGTTTCAATAAAGTAA
TTTAATAAATAATCACATTGGTAGCACGA

hide sequence

RefSeq Acc Id:

XM_039083302 ⟹ XP_038939230

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	60,001,631 - 60,037,965 (-)	NCBI

RefSeq Acc Id:

XM_039083303 ⟹ XP_038939231

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	60,001,631 - 60,038,300 (-)	NCBI

RefSeq Acc Id:

XM_039083305 ⟹ XP_038939233

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	60,001,631 - 60,038,301 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001012003	(Get FASTA)	NCBI Sequence Viewer
	XP_006245018	(Get FASTA)	NCBI Sequence Viewer
	XP_017451849	(Get FASTA)	NCBI Sequence Viewer
	XP_038939230	(Get FASTA)	NCBI Sequence Viewer
	XP_038939231	(Get FASTA)	NCBI Sequence Viewer
	XP_038939233	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAD12235	(Get FASTA)	NCBI Sequence Viewer
	EDL98988	(Get FASTA)	NCBI Sequence Viewer
	Q75PQ8	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001012003 ⟸ NM_001012003

- UniProtKB:

Q75PQ8 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MSTLRLKEAKVPSVQFVGDDDVLSHILDREGGTKLKKEKVQLLVNPQKVIKKAECELEKSDLEV
LEDQNYVEVLGRNIQESLGNGSAVDGRNKVYSFQHRKHPEEMTKLALELAKTSGKIDPLASNDP
KITKNIARKSKGHSSEKAPLENNNKNEFPSIQPHNVRKRLIASRSHCDSESEYSASSSEDDEEV
AKDDEEDTNVVRCSKKSQGQNRLLPAPVSKEILPKKRKRDKAGDLVEEYFEAHSSSKVLTSDRT
LQKLRRARVDQKTLRNLLSKFVPSFSTEIGQLNQQHERLFDKWILQLRLGFNIVLYGLGSKRDL
LEKFRTTMLQDSIHVVINGFFPGISVKSILNSITEDVLSHMGTFQSVLDQRDWIMNRFKEDSSL
ELFLLIHNLDSQMLRGDNSQQILGQLSSLRNVYLIASIDHLNAPLMWDHAKQSLYNWLWYETTT
YSPYTEETSYENSLLVKQSGSLPLSSLIHVLRSLTPNARGIFRLLMKYQLDNQDCPSYIGLSFQ
DFYQQCREAFLVNSDLTLRAQLTEFRDHKLIRTKKGTDGVEYLLIPVDSGTLADFLEKEEEEES

hide sequence

RefSeq Acc Id:	XP_006245018 ⟸ XM_006244956
- Peptide Label:	isoform X1
- UniProtKB:	Q75PQ8 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MSTLRLKEAKVPSVQFVGDDDVLSHILDREGGTKLKKEKVQLLVNPQKVIKKAECELEKSDLEV LEDQNYVEVLGRNIQESLGNGSAVDGRNKVYSFQHRKHPEEMTKLALELAKTSGKIDPLASNDP KITKNIARKSKGHSSEKAPLENNNKNEFPSIQPHNVRKRLIASRSHCDSESEYSASSSEDDEEV AKDDEEDTNVVRCSKKSQGQNRLLPAPVSKEILPKKRKRDKAGDLVEEYFEAHSSSKVLTSDRT LQKLRRARVDQKTLRNLLSKFVPSFSTEIGQLNQQHERLFDKWILQLRLGFNIVLYGLGSKRDL LEKFRTTMLQDSIHVVINGFFPGISVKSILNSITEDVLSHMGTFQSVLDQRDWIMNRFKEDSSL ELFLLIHNLDSQMLRGDNSQQILGQLSSLRNVYLIASIDHLNAPLMWDHAKQSLYNWLWYETTT YSPYTEETSYENSLLVKQSGSLPLSSLIHVLRSLTPNARGIFRLLMKYQLDNQDCPSYIGLSFQ DFYQQCREAFLVNSDLTLRAQLTEFRDHKLIRTKKGTDGVEYLLIPVDSGTLADFLEKEEEEES hide sequence

RefSeq Acc Id:

XP_017451849 ⟸ XM_017596360

- Peptide Label:

isoform X2

- Sequence:

show sequence

MSTLRLKEAKVPSVQFVGDDDVLSHILDREGGTKLKKEKVQLLVNPQKVIKKAECELEKSDLEV
LEDQNYVEVLGRNIQESLGNGSAVDGRNKVYSFQHRKHPEEMTKLALELAKTSGKIDPLASNDP
KITKNIARKSKASRSHCDSESEYSASSSEDDEEVAKDDEEDTNVVRCSKKSQGQNRLLPAPVSK
EILPKKRKRDKAGDLVEEYFEAHSSSKVLTSDRTLQKLRRARVDQKTLRNLLSKFVPSFSTEIG
QLNQQHERLFDKWILQLRLGFNIVLYGLGSKRDLLEKFRTTMLQDSIHVVINGFFPGISVKSIL
NSITEDVLSHMGTFQSVLDQRDWIMNRFKEDSSLELFLLIHNLDSQMLRGDNSQQILGQLSSLR
NVYLIASIDHLNAPLMWDHAKQSLYNWLWYETTTYSPYTEETSYENSLLVKQSGSLPLSSLIHV
LRSLTPNARGIFRLLMKYQLDNQDCPSYIGLSFQDFYQQCREAFLVNSDLTLRAQLTEFRDHKL
IRTKKGTDGVEYLLIPVDSGTLADFLEKEEEEES

hide sequence

RefSeq Acc Id:

ENSRNOP00000042867 ⟸ ENSRNOT00000051843

RefSeq Acc Id:	XP_038939233 ⟸ XM_039083305
- Peptide Label:	isoform X1
- UniProtKB:	Q75PQ8 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038939231 ⟸ XM_039083303
- Peptide Label:	isoform X1
- UniProtKB:	Q75PQ8 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038939230 ⟸ XM_039083302
- Peptide Label:	isoform X1
- UniProtKB:	Q75PQ8 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:

ENSRNOP00000079927 ⟸ ENSRNOT00000099033

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q75PQ8-F1-model_v2	AlphaFold	Q75PQ8	1-576	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696689

Promoter ID:

EPDNEW_R7214

Type:

initiation region

Name:

Orc2_1

Description:

origin recognition complex, subunit 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	65,387,151 - 65,387,211	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311844	AgrOrtholog
BioCyc Gene	G2FUF-27446	BioCyc
Ensembl Genes	ENSRNOG00000012558	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000042867	ENTREZGENE
	ENSRNOP00000042867.3	UniProtKB/Swiss-Prot
	ENSRNOP00000079927	ENTREZGENE
	ENSRNOP00000079927.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000051843	ENTREZGENE
	ENSRNOT00000051843.5	UniProtKB/Swiss-Prot
	ENSRNOT00000099033	ENTREZGENE
	ENSRNOT00000099033.1	UniProtKB/TrEMBL
InterPro	ORC2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:301430	UniProtKB/Swiss-Prot
NCBI Gene	301430	ENTREZGENE
PANTHER	ORIGIN RECOGNITION COMPLEX SUBUNIT 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR14052	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	ORC2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Orc2	PhenoGen
UniProt	A0A8I5ZNQ6_RAT	UniProtKB/TrEMBL
	ORC2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-02	Orc2	origin recognition complex, subunit 2	Orc2l	origin recognition complex, subunit 2-like (yeast)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-24	Orc2l	origin recognition complex, subunit 2-like (yeast)	Orc2l	origin recognition complex, subunit 2-like (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Orc2l	origin recognition complex, subunit 2-like (S. cerevisiae)	Orc2l_predicted	origin recognition complex, subunit 2-like (S. cerevisiae) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Orc2l_predicted	origin recognition complex, subunit 2-like (S. cerevisiae) (predicted)			Symbol and Name status set to approved	70820	APPROVED

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Imported Disease Annotations - ClinVar