Advanced Search (OLGA)

Gene: Mob4 (MOB family member 4, phocein) Rattus norvegicus

Analyze

Symbol:

Mob4

Name:

MOB family member 4, phocein

RGD ID:

620183

Description:

Enables kinase binding activity. Predicted to be involved in negative regulation of hippo signaling. Located in several cellular components, including dendritic spine; neuronal cell body; and perinuclear region of cytoplasm. Orthologous to human MOB4 (MOB family member 4, phocein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; ammonium chloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

class II mMOB1; MOB-like protein phocein; mob1 homolog 3; MOB1, Mps One Binder kinase activator-like 3; MOB1, Mps One Binder kinase activator-like 3 (yeast); mob3; Mobkl1; Mobkl3; mps one binder kinase activator-like 3; phocein; phocein, Mob-like protein; Phocn; Prei3; preimplantation protein 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MOB4 (MOB family member 4, phocein)	HGNC	Ensembl, HomoloGene, Inparanoid, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Mob4 (MOB family member 4, phocein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HSPE1 (heat shock 10kDa protein 1 (chaperonin 10))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MOBKL3 (MOB family member 4, phocein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HSPE1 (heat shock protein family E (Hsp10) member 1)	HGNC	OrthoDB
Homo sapiens (human):	HSPE1-MOB4 (HSPE1-MOB4 readthrough)	HGNC	EggNOG
Alliance orthologs ³
Mus musculus (house mouse):	Mob4 (MOB family member 4, phocein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MOB4 (MOB family member 4, phocein)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mob4 (MOB family member 4, phocein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mob-4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Mob4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mob4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	64,111,170 - 64,135,740 (+)	NCBI		GRCr8
mRatBN7.2	9	56,617,374 - 56,641,336 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	56,617,368 - 56,641,329 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	65,126,329 - 65,150,264 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	70,242,230 - 70,266,164 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	68,541,958 - 68,565,908 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	61,720,583 - 61,744,532 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	61,720,583 - 61,744,531 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	61,403,860 - 61,427,809 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	53,922,795 - 53,946,745 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	53,924,208 - 53,948,158 (+)	NCBI
Celera	9	54,098,848 - 54,122,811 (+)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-nitropyrene (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

8-Br-cAMP (ISO)

aconitine (EXP)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

C60 fullerene (EXP)

cadmium dichloride (EXP,ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

choline (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

DDE (ISO)

dextran sulfate (ISO)

dioxygen (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

Evodiamine (ISO)

flavonoids (EXP)

folic acid (ISO)

FR900359 (ISO)

gold atom (ISO)

gold(0) (ISO)

indole-3-methanol (EXP)

inulin (ISO)

L-methionine (ISO)

lead(0) (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylisothiazolinone (ISO)

N(4)-hydroxycytidine (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

rotenone (EXP)

sulforaphane (ISO)

tacrolimus hydrate (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of hippo signaling (ISO,ISS)

vesicle budding from membrane (TAS)

Cellular Component

cytoplasm (IBA,IDA)

dendritic spine (IDA)

FAR/SIN/STRIPAK complex (ISO,ISS)

glutamatergic synapse (ISO)

Golgi apparatus (IDA,ISO)

Golgi cisterna membrane (IEA)

neuronal cell body (IDA)

perinuclear region of cytoplasm (IDA)

postsynapse (ISO)

Molecular Function

kinase binding (IPI)

metal ion binding (IEA)

protein binding (IPI,ISO)

protein-macromolecule adaptor activity (ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Interactions of phocein with nucleoside-diphosphate kinase, Eps15, and Dynamin I.	Baillat G, etal., J Biol Chem 2002 May 24;277(21):18961-6.
2.	Molecular cloning and characterization of phocein, a protein found from the Golgi complex to dendritic spines.	Baillat G, etal., Mol Biol Cell 2001 Mar;12(3):663-73.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:18466332	PMID:30053369

Genomics

Comparative Map Data

Mob4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	64,111,170 - 64,135,740 (+)	NCBI		GRCr8
mRatBN7.2	9	56,617,374 - 56,641,336 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	56,617,368 - 56,641,329 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	65,126,329 - 65,150,264 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	70,242,230 - 70,266,164 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	68,541,958 - 68,565,908 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	61,720,583 - 61,744,532 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	61,720,583 - 61,744,531 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	61,403,860 - 61,427,809 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	53,922,795 - 53,946,745 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	53,924,208 - 53,948,158 (+)	NCBI
Celera	9	54,098,848 - 54,122,811 (+)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

MOB4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	197,515,554 - 197,553,699 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	197,515,571 - 197,553,699 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	198,380,278 - 198,418,423 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	198,088,565 - 198,125,760 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	192,136,193 - 192,173,386 (+)	NCBI		Celera
Cytogenetic Map	2	q33.1	NCBI
HuRef	2	190,232,691 - 190,270,816 (+)	NCBI		HuRef
CHM1_1	2	198,386,134 - 198,424,264 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	197,999,154 - 198,037,300 (+)	NCBI		T2T-CHM13v2.0

Mob4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	55,170,404 - 55,194,058 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	55,170,390 - 55,194,058 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	55,131,245 - 55,154,899 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	55,131,231 - 55,154,899 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	55,188,089 - 55,211,743 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	55,075,838 - 55,098,646 (+)	NCBI		MGSCv36	mm8
Celera	1	55,651,452 - 55,675,027 (+)	NCBI		Celera
Cytogenetic Map	1	C1.2	NCBI
cM Map	1	28.03	NCBI

HSPE1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	7,020,507 - 7,063,678 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	7,035,829 - 7,062,213 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	7,966,857 - 8,009,888 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	6,910,995 - 6,954,039 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	6,926,127 - 6,954,089 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	6,909,827 - 6,952,869 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	6,876,745 - 6,917,729 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	6,899,891 - 6,942,950 (+)	NCBI		UU_Cfam_GSD_1.0

MOBKL3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	101,390,917 - 101,420,447 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	101,390,913 - 101,420,282 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	112,565,015 - 112,591,016 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	484
Count of miRNA genes:	258
Interacting mature miRNAs:	328
Transcripts:	ENSRNOT00000020536
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	6714888	84474983	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56047863	101047863	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	40029925	85029925	Rat
1582203	Gluco19	Glucose level QTL 19	3.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	63376862	108376862	Rat
1300180	Bw14	Body weight QTL 14	3.776		body mass (VT:0001259)	body weight (CMO:0000012)	9	31250432	68875676	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	44458256	99506504	Rat
61450	Ciaa3	CIA Autoantibody QTL 3	6.5		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	9	29567664	74567664	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	44458256	85262605	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	29567664	83835942	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	41720295	86720295	Rat
7207805	Bmd88	Bone mineral density QTL 88	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	9	31250432	65651574	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	44458256	121768150	Rat
1581517	Bp284	Blood pressure QTL 284			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	39220186	84220186	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	48718864	108376862	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	40029925	85029925	Rat
1598849	Memor17	Memory QTL 17	2.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	57460497	78547958	Rat
4889943	Bss90	Bone structure and strength QTL 90	4.1		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	9	54506504	99506504	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	34960590	79960590	Rat

Markers in Region

D9Mco76

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	56,627,713 - 56,627,933 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	61,730,923 - 61,731,138	NCBI	Rnor6.0
Rnor_5.0	9	61,414,200 - 61,414,415	UniSTS	Rnor5.0
RGSC_v3.4	9	53,933,135 - 53,933,350	UniSTS	RGSC3.4
Celera	9	54,109,188 - 54,109,403	UniSTS
Cytogenetic Map	9	q31	UniSTS

RH129911

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	56,640,909 - 56,641,092 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	61,744,106 - 61,744,288	NCBI	Rnor6.0
Rnor_5.0	9	61,427,383 - 61,427,565	UniSTS	Rnor5.0
RGSC_v3.4	9	53,946,319 - 53,946,501	UniSTS	RGSC3.4
Celera	9	54,122,385 - 54,122,567	UniSTS
RH 3.4 Map	9	476.98	UniSTS
Cytogenetic Map	9	q31	UniSTS

RH143767

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	56,617,875 - 56,618,032 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	61,721,085 - 61,721,241	NCBI	Rnor6.0
Rnor_5.0	9	61,404,362 - 61,404,518	UniSTS	Rnor5.0
RGSC_v3.4	9	53,923,297 - 53,923,453	UniSTS	RGSC3.4
Celera	9	54,099,350 - 54,099,506	UniSTS
RH 3.4 Map	9	477.98	UniSTS
Cytogenetic Map	9	q31	UniSTS

RH138957

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	56,640,720 - 56,640,929 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	61,743,917 - 61,744,125	NCBI	Rnor6.0
Rnor_5.0	9	61,427,194 - 61,427,402	UniSTS	Rnor5.0
RGSC_v3.4	9	53,946,130 - 53,946,338	UniSTS	RGSC3.4
Celera	9	54,122,196 - 54,122,404	UniSTS
RH 3.4 Map	9	479.57	UniSTS
Cytogenetic Map	9	q31	UniSTS

RH140245

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	56,640,982 - 56,641,195 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	61,744,179 - 61,744,391	NCBI	Rnor6.0
Rnor_5.0	9	61,427,456 - 61,427,668	UniSTS	Rnor5.0
RGSC_v3.4	9	53,946,392 - 53,946,604	UniSTS	RGSC3.4
Celera	9	54,122,458 - 54,122,670	UniSTS
RH 3.4 Map	9	477.67	UniSTS
Cytogenetic Map	9	q31	UniSTS

AA818419

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	56,639,413 - 56,639,531 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	61,742,610 - 61,742,727	NCBI	Rnor6.0
Rnor_5.0	9	61,425,887 - 61,426,004	UniSTS	Rnor5.0
RGSC_v3.4	9	53,944,823 - 53,944,940	UniSTS	RGSC3.4
Celera	9	54,120,900 - 54,121,017	UniSTS
RH 3.4 Map	9	477.87	UniSTS
Cytogenetic Map	9	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133528	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC103419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ132008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000020536 ⟹ ENSRNOP00000020536

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	56,617,368 - 56,641,329 (+)	Ensembl
Rnor_6.0 Ensembl	9	61,720,583 - 61,744,531 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096080 ⟹ ENSRNOP00000084702

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	56,617,381 - 56,641,328 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103898 ⟹ ENSRNOP00000092795

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	56,617,375 - 56,641,328 (+)	Ensembl

RefSeq Acc Id:

NM_133528 ⟹ NP_598212

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	64,111,789 - 64,135,740 (+)	NCBI
mRatBN7.2	9	56,617,374 - 56,641,336 (+)	NCBI
Rnor_6.0	9	61,720,583 - 61,744,532 (+)	NCBI
Rnor_5.0	9	61,403,860 - 61,427,809 (+)	NCBI
RGSC_v3.4	9	53,922,795 - 53,946,745 (+)	RGD
Celera	9	54,098,848 - 54,122,811 (+)	RGD

Sequence:

show sequence

TGGCACTATGGTCATGGCGGAGGGGACGGCAGTGCTGAGGCGGAACAGGCCAGGCACCAAGGCG
CAGGATTTCTATAATTGGCCTGATGAATCATTTGATGAAATGGACAGTACACTTGCTGTTCAGC
AGTATATTCAACAGAACATAAGGGCAGACTGCTCCAATATTGACAAAATTCTTGAACCACCTGA
AGGTCAAGATGAAGGTGTATGGAAGTATGAACATTTAAGGCAATTCTGCCTTGAACTAAATGGA
CTTGCTGTCAAACTTCAGAGTGAGTGCCATCCTGATACTTGTACTCAGATGACAGCAACTGAAC
AATGGATTTTTCTTTGTGCAGCTCATAAAACTCCAAAAGAGTGTCCTGCCATAGATTATACAAG
ACACACACTGGATGGTGCTGCATGTCTTCTGAATAGCAATAAATATTTTCCCAGCAGGGTTAGC
ATAAAAGAATCATCTGTAGCAAAACTAGGATCAGTGTGCCGTAGGATTTACAGAATATTCTCAC
ATGCCTATTTTCATCACCGGCAGATATTTGATGAATATGAAAATGAAACATTTTTATGTCACCG
GTTTACCAAATTTGTGATGAAATATAATTTGATGTCGAAGGATAACCTGATTGTACCAATTTTA
GAAGAGGAAGTTCAGAATTCAGTTTCTGGGGAAAGTGAAGCATGAAGGAATCATGTAGAACAAT
GTACTGATCACATAATTAACAATTATGTACTGTATATATATCATTTTAGACACATCAATCATGT
ATCCATATTATAGCTTATTTGTTTAGTATAGGTTTTTGTATGCTATGTGTTGCCTTTTTAAATG
GGAAATACATTTTAAGTTATTCATGAGCTGTATATTCACTGGTGTGGCACTCATGGTTTTTAAA
TAAGTTTAGTATTATCTGTTTATAATGCCTGTTAATAAAAGAATTTACAGTTTGGTATAATTGC
TGCTAAACAATCATTGGATCACAATCCTCTCAAATCTATAAAGGAATGAACTTGTGTCTCACAC
AAGTATTTACAATTACTAAAGAGAATATTTTGTTTTCACCCCTAAGATTTAATATTTTAGGAAA
TTCAGTAGTATTCCATCTGTACTGTTAATTTTTCCAAAATGAGATAAAAGTGTTTAAGAGTTCT
GTTTATAGCTTTTGATATGCATAACTGATTATGTGTGTGTTCAGAGAAATTCGAGGAGGTGTTA
GTAATAAATTATCTCTCTCTTCTACATAAAGTATCCTTTAGGTCAGTGTACATGGAAGCATTAC
CTTTGCTATGGCAGTGCATTATTAAATACATGGTGAGGAGGAGGAGGCACATACATGATGTTCC
CATGGACACCCACCCGCCCCTTGTTTCCCTTAGTCCTCTGGGAAGTATACTAGTCATGAAATTT
ACTTACCAAGCTATGGTTAGTGGTGGCTTTTCCCTATTTATACTGTATTAATTGCTTACAGAGC
ATACCTCATACTAGCAGTGACGTTACACTACAGGGAAACTGGACTGCCTACCTTTGTTTTTTAA
AATGGTTGTAACTACTTAGAAAATAGTCCTTAATATAGTTTGACTTTTCCTGTTAGTAATATTA
ATCTTTTCACCTAGCCCTAGGCAGCATTAAATAGATATGAAAAAAAAGATAGTGTATTTATTTT
ATTCTCCCTCCTTAAAAGCTTATTGTTCTAATTATATGCACATGTAAGACTATTTACAATAATT
CACAGGTTAAGTGCTGTTGATAAGTGGTCATACTTTGATTTCTTATTTCAGTGTCTTAAGAATT
TAAGTGCAGACTTAGATAACATGATTGGTGGAGTTTCTCTTTAAACACTGAGGTCTCTATGCCA
CACTGTAGCAAGGCACTGAGATGAAACAGAGACCTGTGCAGTTGGGACAATTGAAGCCATCTTT
TCCAATTTAATAAACACAAGAAACTTCTTTTTTATTTAAGAGCTATTTGCAAATGAAATTGAAA
AATGCATTCATCTTGTTTGTTTTTCTAATTATTTGAAGAAATGATTTGTATTGTATTATAAGAC
AAGTATACACAGAAAAATTGGGAAGTGAGAGCAAACTGAGAGTGTGTGTATAGTTGACGCCTGT
CTGAACCTGTGCTGTGCCAGCGGTCACAGTCATCACTGTACCTGAGCCCACAGTTATCTTCTGA
GAAGTTCATGTATGCAGTGAATAGAACATTGACTGAAATTGGGTGTTTATATTACTGTCACCAT
AAATCATTGGGGTTAGTAATTTTAATAAACTTGGTAGATATGAGAGACTAACCTATACTAAGTT
CATAAATTATACATAGCCTAGTAATGTTGCTGTTCTCTAGTTGGAGTCCCCGGTGGAGTCCTGT
TGTTTGACTTGCTCAGTGAGCAGTTAAGGCAGGTGGAGACCTGACTGAGTACTTGGAACACTTT
GTGAATATATGGCTTAGTGTTAACAGGAAAATAAAGTGTGGTTTTCTTTTTATACTTACTCCAA
AAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_063266616 ⟹ XP_063122686

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	64,111,170 - 64,135,735 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_598212	(Get FASTA)	NCBI Sequence Viewer
	XP_063122686	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH85708	(Get FASTA)	NCBI Sequence Viewer
	CAB57295	(Get FASTA)	NCBI Sequence Viewer
	EDL99048	(Get FASTA)	NCBI Sequence Viewer
	EDL99049	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000020536.3
	ENSRNOP00000084702.1
	ENSRNOP00000092795.1
	ENSRNOP00055005532
	ENSRNOP00060035631
	ENSRNOP00065003109
GenBank Protein	Q9QYW3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_598212 ⟸ NM_133528

- UniProtKB:

Q9QYW3 (UniProtKB/Swiss-Prot), A6IP11 (UniProtKB/TrEMBL), A0A8L2QA94 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEPPEGQ
DEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECPAIDYTRHT
LDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYENETFLCHRFT
KFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA

hide sequence

Ensembl Acc Id:

ENSRNOP00000020536 ⟸ ENSRNOT00000020536

Ensembl Acc Id:

ENSRNOP00000092795 ⟸ ENSRNOT00000103898

Ensembl Acc Id:

ENSRNOP00000084702 ⟸ ENSRNOT00000096080

RefSeq Acc Id:	XP_063122686 ⟸ XM_063266616
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9QYW3-F1-model_v2	AlphaFold	Q9QYW3	1-225	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696672

Promoter ID:

EPDNEW_R7196

Type:

initiation region

Name:

Mob4_1

Description:

MOB family member 4, phocein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	61,720,577 - 61,720,637	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620183	AgrOrtholog
BIND	129608
	130460
	134478
BioCyc Gene	G2FUF-27532	BioCyc
Ensembl Genes	ENSRNOG00000014980	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055004639	UniProtKB/Swiss-Prot
	ENSRNOG00060024835	UniProtKB/Swiss-Prot
	ENSRNOG00065003089	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000020536.5	UniProtKB/TrEMBL
	ENSRNOT00000096080.1	UniProtKB/TrEMBL
	ENSRNOT00000103898.1	UniProtKB/Swiss-Prot
	ENSRNOT00055007374	UniProtKB/Swiss-Prot
	ENSRNOT00060043054	UniProtKB/Swiss-Prot
	ENSRNOT00065004355	UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.140.30	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7193103	IMAGE-MGC_LOAD
InterPro	MOB_kinase_act_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MOB_kinase_act_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:171050	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:93220	IMAGE-MGC_LOAD
NCBI Gene	171050	ENTREZGENE
PANTHER	MOB-LIKE PROTEIN PHOCEIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR22599	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Mob1_phocein	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Mob4	PhenoGen
RatGTEx	ENSRNOG00000014980	RatGTEx
	ENSRNOG00055004639	RatGTEx
	ENSRNOG00060024835	RatGTEx
	ENSRNOG00065003089	RatGTEx
SMART	Mob1_phocein	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF101152	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6GC42_RAT	UniProtKB/TrEMBL
	A0A8L2QA94	ENTREZGENE, UniProtKB/TrEMBL
	A6IP11	ENTREZGENE, UniProtKB/TrEMBL
	PHOCN_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-10-18	Mob4	MOB family member 4, phocein	Phocn	phocein, Mob-like protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-09-02	Phocn	phocein, Mob-like protein	Mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-19	Mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	Prei3	preimplantation protein 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Prei3	preimplantation protein 3			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Prei3	preimplantation protein 3			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized to membrane fractions	633583
gene_expression	protein is detected in adult brain neurons	633583

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar