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Gene: Pikfyve (phosphoinositide kinase, FYVE-type zinc finger containing) Rattus norvegicus
Symbol: Pikfyve
Name: phosphoinositide kinase, FYVE-type zinc finger containing
Description: Predicted to have 1-phosphatidylinositol-4-phosphate 5-kinase activity and zinc ion binding activity. Predicted to be involved in several processes, including myelin assembly; regulation of autophagosome assembly; and retrograde transport, endosome to Golgi. Predicted to localize to several cellular components, including early endosome membrane; membrane raft; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in Fleck corneal dystrophy. Orthologous to human PIKFYVE (phosphoinositide kinase, FYVE-type zinc finger containing); PARTICIPATES IN inositol metabolic pathway; phosphoinositide metabolic pathway; inositol phosphate metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: 1-phosphatidylinositol 3-phosphate 5-kinase; 1-phosphatidylinositol-3-phosphate 5-kinase; LOC316457; phosphatidylinositol-3-phosphate 5-kinase type III; phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III; phosphoinositide kinase, FYVE finger containing; Pip5k3; similar to phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III isoform 2
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0971,911,744 - 72,005,816 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl971,915,421 - 72,005,838 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0970,566,016 - 70,660,374 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4963,798,743 - 63,890,905 (+)NCBIRGSC3.4rn4RGSC3.4
Celera963,959,029 - 64,052,994 (+)NCBICelera
Cytogenetic Map9q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Pikfyve
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1592067
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.