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Gene: Ihh (Indian hedgehog signaling molecule) Rattus norvegicus
Symbol: Ihh
Name: Indian hedgehog signaling molecule
RGD ID: 620021
Description: Predicted to have calcium ion binding activity and patched binding activity. Involved in several processes, including liver regeneration; maternal process involved in female pregnancy; and response to estradiol. Predicted to localize to extracellular matrix; extracellular space; and plasma membrane. Biomarker of osteoarthritis. Human ortholog(s) of this gene implicated in acrocapitofemoral dysplasia; brachydactyly type A1; retinopathy of prematurity; and syndactyly type 1. Orthologous to human IHH (Indian hedgehog signaling molecule); PARTICIPATES IN Hedgehog signaling pathway; INTERACTS WITH (+)-schisandrin B; (S)-nicotine; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Indian hedgehog; indian hedgehog homolog; Indian hedgehog homolog, (Drosophila)
Homo sapiens (human) : IHH (Indian hedgehog signaling molecule)  HGNC  Alliance
Mus musculus (house mouse) : Ihh (Indian hedgehog)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ihh (Indian hedgehog signaling molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : IHH (Indian hedgehog signaling molecule)
Canis lupus familiaris (dog) : IHH (Indian hedgehog signaling molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ihh (Indian hedgehog signaling molecule)
Sus scrofa (pig) : IHH (Indian hedgehog signaling molecule)
Chlorocebus sabaeus (African green monkey) : IHH (Indian hedgehog signaling molecule)
Heterocephalus glaber (naked mole-rat) : Ihh (Indian hedgehog signaling molecule)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0982,208,223 - 82,214,440 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,208,223 - 82,214,440 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,977,484 - 81,983,701 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,287,115 - 74,293,332 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1974,435,304 - 74,439,783 (-)NCBI
Celera974,074,990 - 74,081,207 (-)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ihh
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620021
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.