Obsl1 (obscurin like cytoskeletal adaptor 1) - Rat Genome Database

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Gene: Obsl1 (obscurin like cytoskeletal adaptor 1) Rattus norvegicus
Analyze
Symbol: Obsl1
Name: obscurin like cytoskeletal adaptor 1
RGD ID: 1306073
Description: Involved in Golgi organization and positive regulation of dendrite morphogenesis. Predicted to be located in Golgi apparatus; centrosome; and perinuclear region of cytoplasm. Predicted to be part of 3M complex. Human ortholog(s) of this gene implicated in 3-M syndrome. Orthologous to human OBSL1 (obscurin like cytoskeletal adaptor 1); INTERACTS WITH 1,3-dinitrobenzene; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363259; obscurin-like 1; Obscurin-like protein 1; RGD1306073; similar to sallimus CG1915-PC
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8984,416,447 - 84,442,415 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl984,416,240 - 84,442,415 (-)EnsemblGRCr8
mRatBN7.2976,967,802 - 76,993,771 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,974,253 - 76,993,560 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx985,428,497 - 85,437,799 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,557,376 - 90,566,678 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,943,555 - 88,952,857 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,673,871 - 82,699,577 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,680,384 - 82,699,551 (-)Ensemblrn6Rnor6.0
Rnor_5.0982,449,529 - 82,468,832 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4974,761,815 - 74,780,292 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera974,544,146 - 74,563,437 (-)NCBICelera
RGSC_v3.1974,918,133 - 74,928,210 (-)NCBI
Cytogenetic Map9q33NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
alpha-Zearalanol  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glycidyl methacrylate  (ISO)
indometacin  (ISO)
inulin  (ISO)
L-methionine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (EXP,ISO)
methamphetamine  (EXP)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
propanal  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
thimerosal  (ISO)
titanium dioxide  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
3M complex  (IEA,ISO,ISS)
centrosome  (IEA,ISO,ISS)
cytoplasm  (IEA,ISO,ISS)
Golgi apparatus  (IEA,ISO,ISS)
perinuclear region of cytoplasm  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning. Litterman N, etal., PLoS Biol. 2011 May;9(5):e1001060. doi: 10.1371/journal.pbio.1001060. Epub 2011 May 10.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15057822   PMID:17289344   PMID:18477606   PMID:24793695  


Genomics

Comparative Map Data
Obsl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8984,416,447 - 84,442,415 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl984,416,240 - 84,442,415 (-)EnsemblGRCr8
mRatBN7.2976,967,802 - 76,993,771 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,974,253 - 76,993,560 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx985,428,497 - 85,437,799 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,557,376 - 90,566,678 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,943,555 - 88,952,857 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,673,871 - 82,699,577 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,680,384 - 82,699,551 (-)Ensemblrn6Rnor6.0
Rnor_5.0982,449,529 - 82,468,832 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4974,761,815 - 74,780,292 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera974,544,146 - 74,563,437 (-)NCBICelera
RGSC_v3.1974,918,133 - 74,928,210 (-)NCBI
Cytogenetic Map9q33NCBI
OBSL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,547,206 - 219,571,539 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,550,728 - 219,571,859 (-)Ensemblhg38GRCh38
GRCh372220,415,450 - 220,436,261 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,123,708 - 220,144,255 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2214,185,413 - 214,206,231 (-)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2212,268,480 - 212,289,298 (-)NCBIHuRef
CHM1_12220,421,271 - 220,442,089 (-)NCBICHM1_1
T2T-CHM13v2.02220,034,047 - 220,056,240 (-)NCBIT2T-CHM13v2.0
Obsl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39175,462,469 - 75,483,134 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl175,455,954 - 75,483,096 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38175,485,825 - 75,506,486 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl175,479,310 - 75,506,452 (-)Ensemblmm10GRCm38
MGSCv37175,482,400 - 75,503,027 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36175,373,687 - 75,388,789 (-)NCBIMGSCv36mm8
Celera175,975,184 - 75,995,750 (-)NCBICelera
Cytogenetic Map1C4NCBI
cM Map139.15NCBI
Obsl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545313,906,013 - 13,925,681 (+)Ensembl
ChiLan1.0NW_00495545313,905,992 - 13,932,652 (+)NCBIChiLan1.0ChiLan1.0
OBSL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213122,180,903 - 122,201,538 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B122,193,304 - 122,216,801 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B106,805,441 - 106,828,937 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B225,402,614 - 225,419,008 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B225,398,863 - 225,418,567 (-)EnsemblpanPan2panpan1.1
OBSL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13726,059,713 - 26,079,503 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3726,059,713 - 26,079,488 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3726,885,157 - 26,904,946 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03726,074,790 - 26,094,606 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3726,074,849 - 26,094,702 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,978,673 - 25,998,589 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,914,789 - 25,934,580 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,935,380 - 25,955,192 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Obsl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303175,588,260 - 175,606,915 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365691,929,069 - 1,949,708 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365691,930,189 - 1,949,735 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OBSL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15121,560,008 - 121,581,188 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115121,560,009 - 121,581,314 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215134,512,265 - 134,533,024 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OBSL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110105,445,800 - 105,467,187 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10105,442,071 - 105,466,875 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604093,934,250 - 93,955,442 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Obsl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248235,491,779 - 5,511,202 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248235,491,644 - 5,518,222 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Obsl1
392 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:65
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000020673
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)98216882386720295Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat

Markers in Region
D9Wox10  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,994,123 - 76,994,246 (+)MAPPERmRatBN7.2
Rnor_6.0982,700,141 - 82,700,263NCBIRnor6.0
Rnor_5.0982,469,402 - 82,469,524UniSTSRnor5.0
RGSC_v3.4974,780,881 - 74,781,004RGDRGSC3.4
RGSC_v3.4974,780,882 - 74,781,004UniSTSRGSC3.4
Celera974,564,001 - 74,564,123UniSTS
RGSC_v3.1974,927,989 - 74,928,112RGD
RH 3.4 Map9757.3UniSTS
RH 3.4 Map9757.3RGD
Cytogenetic Map9q33UniSTS
D9Mco56  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,989,207 - 76,989,394 (+)MAPPERmRatBN7.2
Rnor_6.0982,695,225 - 82,695,411NCBIRnor6.0
Rnor_5.0982,464,486 - 82,464,672UniSTSRnor5.0
RGSC_v3.4974,775,966 - 74,776,152UniSTSRGSC3.4
Celera974,559,085 - 74,559,271UniSTS
Cytogenetic Map9q33UniSTS
AA859818  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,984,320 - 76,984,527 (+)MAPPERmRatBN7.2
Rnor_6.0982,690,338 - 82,690,544NCBIRnor6.0
Rnor_5.0982,459,599 - 82,459,805UniSTSRnor5.0
RGSC_v3.4974,771,079 - 74,771,285UniSTSRGSC3.4
Celera974,554,198 - 74,554,404UniSTS
RH 3.4 Map9760.3UniSTS
Cytogenetic Map9q33UniSTS
ECD17211  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8984,441,682 - 84,442,090 (+)Marker Load Pipeline
mRatBN7.2976,993,037 - 76,993,446 (+)MAPPERmRatBN7.2
Rnor_6.0982,699,055 - 82,699,463NCBIRnor6.0
Rnor_5.0982,468,316 - 82,468,724UniSTSRnor5.0
RGSC_v3.4974,779,796 - 74,780,204UniSTSRGSC3.4
Celera974,562,915 - 74,563,323UniSTS
Cytogenetic Map9q33UniSTS
REN53413  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2976,992,757 - 76,993,030 (+)MAPPERmRatBN7.2
Rnor_6.0982,698,775 - 82,699,047NCBIRnor6.0
Rnor_5.0982,468,036 - 82,468,308UniSTSRnor5.0
RGSC_v3.4974,779,516 - 74,779,788UniSTSRGSC3.4
Celera974,562,635 - 74,562,907UniSTS
Cytogenetic Map9q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 159 91 90 59 90 59 6 354 190 11 138 81 92 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000020673   ⟹   ENSRNOP00000020673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl984,422,895 - 84,442,415 (-)Ensembl
mRatBN7.2 Ensembl976,974,253 - 76,993,560 (-)Ensembl
Rnor_6.0 Ensembl982,680,384 - 82,699,551 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103263   ⟹   ENSRNOP00000084083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl984,432,904 - 84,442,204 (-)Ensembl
mRatBN7.2 Ensembl976,984,260 - 76,993,560 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120120   ⟹   ENSRNOP00000093392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl984,416,240 - 84,442,415 (-)Ensembl
mRatBN7.2 Ensembl976,974,916 - 76,993,560 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000144816   ⟹   ENSRNOP00000103633
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl984,423,419 - 84,442,415 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000171612   ⟹   ENSRNOP00000101306
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl984,422,784 - 84,442,415 (-)Ensembl
RefSeq Acc Id: NM_001377020   ⟹   NP_001363949
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,432,904 - 84,442,204 (-)NCBI
mRatBN7.2976,984,260 - 76,993,560 (-)NCBI
RefSeq Acc Id: NM_001409045   ⟹   NP_001395974
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,422,895 - 84,442,415 (-)NCBI
mRatBN7.2976,974,250 - 76,993,771 (-)NCBI
RefSeq Acc Id: XM_006245304   ⟹   XP_006245366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,422,895 - 84,442,178 (-)NCBI
mRatBN7.2976,974,250 - 76,993,565 (-)NCBI
Rnor_6.0982,680,268 - 82,699,577 (-)NCBI
Rnor_5.0982,449,529 - 82,468,832 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596828   ⟹   XP_017452317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,416,447 - 84,442,178 (-)NCBI
mRatBN7.2976,967,802 - 76,993,565 (-)NCBI
Rnor_6.0982,673,871 - 82,699,577 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083894   ⟹   XP_038939822
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,429,261 - 84,442,178 (-)NCBI
mRatBN7.2976,980,603 - 76,993,565 (-)NCBI
RefSeq Acc Id: XM_039083895   ⟹   XP_038939823
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,429,261 - 84,442,178 (-)NCBI
mRatBN7.2976,980,603 - 76,993,565 (-)NCBI
RefSeq Acc Id: XM_063267420   ⟹   XP_063123490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,422,895 - 84,442,178 (-)NCBI
RefSeq Acc Id: XM_343599   ⟹   XP_343600
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,422,895 - 84,442,178 (-)NCBI
mRatBN7.2976,974,250 - 76,993,565 (-)NCBI
Rnor_6.0982,680,268 - 82,699,577 (-)NCBI
Rnor_5.0982,449,529 - 82,468,832 (-)NCBI
RGSC_v3.4974,761,815 - 74,780,292 (-)RGD
Sequence:
RefSeq Acc Id: XP_343600   ⟸   XM_343599
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AIN9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245366   ⟸   XM_006245304
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AIN9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452317   ⟸   XM_017596828
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AIN9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020673   ⟸   ENSRNOT00000020673
RefSeq Acc Id: XP_038939823   ⟸   XM_039083895
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038939822   ⟸   XM_039083894
- Peptide Label: isoform X5
- UniProtKB: A6JW41 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001363949   ⟸   NM_001377020
- Peptide Label: isoform 1
- UniProtKB: A0A8I6GBF5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000093392   ⟸   ENSRNOT00000120120
Ensembl Acc Id: ENSRNOP00000084083   ⟸   ENSRNOT00000103263
RefSeq Acc Id: NP_001395974   ⟸   NM_001409045
- Peptide Label: isoform 2
- UniProtKB: D3ZZ80 (UniProtKB/Swiss-Prot),   A0A8I6AIN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123490   ⟸   XM_063267420
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AIN9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000103633   ⟸   ENSRNOT00000144816
Ensembl Acc Id: ENSRNOP00000101306   ⟸   ENSRNOT00000171612
Protein Domains
Fibronectin type-III   Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZ80-F1-model_v2 AlphaFold D3ZZ80 1-1805 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306073 AgrOrtholog
BioCyc Gene G2FUF-27061 BioCyc
Ensembl Genes ENSRNOG00000015346 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020673 ENTREZGENE
  ENSRNOT00000020673.8 UniProtKB/Swiss-Prot
  ENSRNOT00000103263 ENTREZGENE
  ENSRNOT00000120120 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Obscurin/Obscurin-like_Reg UniProtKB/Swiss-Prot
NCBI Gene 363259 ENTREZGENE
PANTHER OBSCURIN-LIKE PROTEIN 1 UniProtKB/Swiss-Prot
  SI:DKEY-31G6.6 UniProtKB/Swiss-Prot
Pfam I-set UniProtKB/Swiss-Prot
  Ig_3 UniProtKB/Swiss-Prot
PhenoGen Obsl1 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot
  IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015346 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
UniProt A0A8I6AIN9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GBF5 ENTREZGENE, UniProtKB/TrEMBL
  A6JW40_RAT UniProtKB/TrEMBL
  A6JW41 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZ80 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-03 Obsl1  obscurin like cytoskeletal adaptor 1  Obsl1  obscurin-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Obsl1  obscurin-like 1  RGD1306073_predicted  similar to sallimus CG1915-PC (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1306073_predicted  similar to sallimus CG1915-PC (predicted)  LOC363259_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC363259_predicted  similar to sallimus CG1915-PC (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL