Npas2 (neuronal PAS domain protein 2) - Rat Genome Database

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Gene: Npas2 (neuronal PAS domain protein 2) Rattus norvegicus
Analyze
Symbol: Npas2
Name: neuronal PAS domain protein 2
RGD ID: 1309681
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; Hsp90 protein binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including positive regulation of DNA repair; positive regulation of behavioral fear response; and regulation of gene expression. Predicted to act upstream of or within circadian sleep/wake cycle and locomotor rhythm. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of CLOCK-BMAL transcription complex. Orthologous to human NPAS2 (neuronal PAS domain protein 2); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC316351; neuronal PAS domain-containing protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8948,959,225 - 49,138,036 (+)NCBIGRCr8
mRatBN7.2941,463,361 - 41,642,322 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl941,463,830 - 41,642,320 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx949,959,731 - 50,138,286 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0955,082,477 - 55,261,036 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0953,364,568 - 53,543,046 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0945,901,262 - 46,081,880 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl945,901,741 - 46,081,880 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0945,590,021 - 45,769,792 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4938,255,362 - 38,434,352 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1938,256,775 - 38,434,671 (+)NCBI
Celera939,213,508 - 39,392,002 (+)NCBICelera
Cytogenetic Map9q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-methoxyethanol  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
Actein  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
alpha-Zearalanol  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
atrazine  (EXP)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bromobenzene  (EXP)
brucine  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carmustine  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
cisplatin  (EXP)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP,ISO)
cocaine hydrochloride  (ISO)
copper(II) chloride  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP)
dibutyl phthalate  (EXP)
dichloromethane  (ISO)
dicrotophos  (ISO)
digoxigenin  (ISO)
dihydroouabain  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
ellagic acid  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
fluoxetine  (ISO)
furan  (EXP)
glafenine  (EXP)
glyphosate  (EXP)
indole-3-methanol  (EXP)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
methamphetamine  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nevirapine  (EXP)
nickel sulfate  (ISO)
paraquat  (EXP)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
phenobarbital  (ISO)
phenytoin  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
streptozocin  (EXP)
strophanthidin  (ISO)
styrene  (ISO)
succimer  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP)
tributylstannane  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
WIN 55212-2  (EXP)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum. Uz T, etal., Neuroscience. 2005;134(4):1309-16. doi: 10.1016/j.neuroscience.2005.05.003.
Additional References at PubMed
PMID:9079689   PMID:9576906   PMID:11441146   PMID:12477932   PMID:12843397   PMID:14645221   PMID:18316400   PMID:18819933   PMID:23831463   PMID:23864491   PMID:24048828   PMID:25212631  
PMID:29163035   PMID:29355377  


Genomics

Comparative Map Data
Npas2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8948,959,225 - 49,138,036 (+)NCBIGRCr8
mRatBN7.2941,463,361 - 41,642,322 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl941,463,830 - 41,642,320 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx949,959,731 - 50,138,286 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0955,082,477 - 55,261,036 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0953,364,568 - 53,543,046 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0945,901,262 - 46,081,880 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl945,901,741 - 46,081,880 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0945,590,021 - 45,769,792 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4938,255,362 - 38,434,352 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1938,256,775 - 38,434,671 (+)NCBI
Celera939,213,508 - 39,392,002 (+)NCBICelera
Cytogenetic Map9q22NCBI
NPAS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382100,818,723 - 100,996,829 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2100,820,139 - 100,996,829 (+)EnsemblGRCh38hg38GRCh38
GRCh372101,436,601 - 101,613,291 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362100,803,045 - 100,979,719 (+)NCBINCBI36Build 36hg18NCBI36
Build 342100,895,130 - 101,071,805NCBI
Celera295,641,227 - 95,817,201 (+)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef295,284,890 - 95,377,330 (+)NCBIHuRef
CHM1_12101,440,965 - 101,617,609 (+)NCBICHM1_1
T2T-CHM13v2.02101,278,833 - 101,455,526 (+)NCBIT2T-CHM13v2.0
Npas2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39139,233,013 - 39,402,321 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl139,232,812 - 39,402,317 (+)EnsemblGRCm39 Ensembl
GRCm38139,193,702 - 39,363,240 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl139,193,731 - 39,363,236 (+)EnsemblGRCm38mm10GRCm38
MGSCv37139,251,117 - 39,420,085 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36139,138,745 - 39,306,732 (+)NCBIMGSCv36mm8
Celera138,989,171 - 39,157,180 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map117.98NCBI
Npas2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554706,831,992 - 6,905,679 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554706,826,541 - 6,906,814 (+)NCBIChiLan1.0ChiLan1.0
NPAS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21227,229,065 - 27,405,686 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A27,231,826 - 27,408,436 (-)NCBINHGRI_mPanPan1
PanPan1.12A101,868,932 - 101,972,923 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A101,868,933 - 101,972,866 (+)Ensemblpanpan1.1panPan2
NPAS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11041,846,766 - 42,005,058 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1041,847,625 - 42,005,469 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1041,771,932 - 41,930,470 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01042,714,471 - 42,873,104 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1042,714,474 - 42,845,094 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11042,426,223 - 42,584,492 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01042,709,720 - 42,868,321 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01042,901,258 - 43,060,042 (-)NCBIUU_Cfam_GSD_1.0
Npas2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629286,320,820 - 86,473,227 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493666195,752 - 210,097 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493666196,312 - 176,395 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPAS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl353,298,811 - 53,490,574 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1353,298,805 - 53,490,375 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2355,845,037 - 56,037,026 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NPAS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1144,529,048 - 4,705,167 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl144,612,225 - 4,705,419 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041172,148,777 - 172,325,348 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Npas2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247495,636,782 - 5,790,779 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247495,636,878 - 5,790,670 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Npas2
907 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:170
Count of miRNA genes:117
Interacting mature miRNAs:145
Transcripts:ENSRNOT00000059571
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat

Markers in Region
RH142343  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2941,642,087 - 41,642,245 (+)MAPPERmRatBN7.2
Rnor_6.0946,081,648 - 46,081,805NCBIRnor6.0
Rnor_5.0945,769,560 - 45,769,717UniSTSRnor5.0
RGSC_v3.4938,434,120 - 38,434,277UniSTSRGSC3.4
Celera939,391,770 - 39,391,927UniSTS
RH 3.4 Map9386.7UniSTS
Cytogenetic Map9q21UniSTS
BF392571  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2941,475,053 - 41,475,258 (+)MAPPERmRatBN7.2
Rnor_6.0945,912,961 - 45,913,165NCBIRnor6.0
Rnor_5.0945,601,241 - 45,601,445UniSTSRnor5.0
RGSC_v3.4938,266,582 - 38,266,786UniSTSRGSC3.4
Celera939,224,728 - 39,224,932UniSTS
RH 3.4 Map9383.3UniSTS
Cytogenetic Map9q21UniSTS
BE119267  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2941,602,281 - 41,602,433 (+)MAPPERmRatBN7.2
Rnor_6.0946,041,846 - 46,041,997NCBIRnor6.0
Rnor_5.0945,729,758 - 45,729,909UniSTSRnor5.0
RGSC_v3.4938,394,316 - 38,394,467UniSTSRGSC3.4
Celera939,351,966 - 39,352,117UniSTS
RH 3.4 Map9386.6UniSTS
Cytogenetic Map9q21UniSTS
Npas2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2941,641,544 - 41,641,814 (+)MAPPERmRatBN7.2
Rnor_6.0946,081,105 - 46,081,374NCBIRnor6.0
Rnor_5.0945,769,017 - 45,769,286UniSTSRnor5.0
RGSC_v3.4938,433,577 - 38,433,846UniSTSRGSC3.4
Celera939,391,227 - 39,391,496UniSTS
Cytogenetic Map9q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 8 6 6 55 12 18 5
Low 3 29 45 31 19 31 8 9 15 23 23 6 8
Below cutoff 6 4 4 4 2 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010054596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010054597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC168989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000059571   ⟹   ENSRNOP00000056327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl941,463,830 - 41,642,320 (+)Ensembl
Rnor_6.0 Ensembl945,901,741 - 46,081,880 (+)Ensembl
RefSeq Acc Id: NM_001108214   ⟹   NP_001101684
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8948,959,565 - 49,138,036 (+)NCBI
mRatBN7.2941,463,830 - 41,642,320 (+)NCBI
Rnor_6.0945,901,741 - 46,081,880 (+)NCBI
Rnor_5.0945,590,021 - 45,769,792 (+)NCBI
RGSC_v3.4938,255,362 - 38,434,352 (+)RGD
Celera939,213,508 - 39,392,002 (+)RGD
Sequence:
RefSeq Acc Id: XM_008767031   ⟹   XP_008765253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8948,959,230 - 49,138,036 (+)NCBI
mRatBN7.2941,463,362 - 41,642,322 (+)NCBI
Rnor_6.0945,901,262 - 46,081,880 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083582   ⟹   XP_038939510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8948,959,230 - 49,138,036 (+)NCBI
mRatBN7.2941,463,361 - 41,642,322 (+)NCBI
RefSeq Acc Id: XM_039083583   ⟹   XP_038939511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8948,959,684 - 49,138,036 (+)NCBI
mRatBN7.2941,463,729 - 41,642,322 (+)NCBI
RefSeq Acc Id: XM_039083584   ⟹   XP_038939512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8948,959,225 - 49,138,036 (+)NCBI
mRatBN7.2941,463,361 - 41,642,322 (+)NCBI
RefSeq Acc Id: XM_039083585   ⟹   XP_038939513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,015,758 - 49,138,036 (+)NCBI
mRatBN7.2941,519,572 - 41,642,322 (+)NCBI
RefSeq Acc Id: XM_039083586   ⟹   XP_038939514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8948,959,230 - 49,138,036 (+)NCBI
mRatBN7.2941,463,361 - 41,642,322 (+)NCBI
RefSeq Acc Id: XM_039083587   ⟹   XP_038939515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,094,515 - 49,138,036 (+)NCBI
mRatBN7.2941,598,801 - 41,642,322 (+)NCBI
RefSeq Acc Id: XM_063267162   ⟹   XP_063123232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8948,959,225 - 49,138,036 (+)NCBI
RefSeq Acc Id: XR_010054596
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8948,959,230 - 49,134,742 (+)NCBI
RefSeq Acc Id: XR_010054597
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8948,959,230 - 49,134,742 (+)NCBI
RefSeq Acc Id: NP_001101684   ⟸   NM_001108214
- UniProtKB: F1MAG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765253   ⟸   XM_008767031
- Peptide Label: isoform X3
- UniProtKB: F1MAG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000056327   ⟸   ENSRNOT00000059571
RefSeq Acc Id: XP_038939512   ⟸   XM_039083584
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038939510   ⟸   XM_039083582
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038939514   ⟸   XM_039083586
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038939511   ⟸   XM_039083583
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038939513   ⟸   XM_039083585
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038939515   ⟸   XM_039083587
- Peptide Label: isoform X4
- UniProtKB: B5DFA7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123232   ⟸   XM_063267162
- Peptide Label: isoform X3
- UniProtKB: F1MAG2 (UniProtKB/TrEMBL)
Protein Domains
bHLH   PAS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1MAG2-F1-model_v2 AlphaFold F1MAG2 1-816 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309681 AgrOrtholog
BioCyc Gene G2FUF-27753 BioCyc
Ensembl Genes ENSRNOG00000013408 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000059571 ENTREZGENE
  ENSRNOT00000059571.3 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro CLOCK-like UniProtKB/TrEMBL
  HLH_DNA-bd UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  Nuc_translocat UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold UniProtKB/TrEMBL
KEGG Report rno:316351 UniProtKB/TrEMBL
NCBI Gene 316351 ENTREZGENE
PANTHER CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT UniProtKB/TrEMBL
  NEURONAL PAS DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS_11 UniProtKB/TrEMBL
PhenoGen Npas2 PhenoGen
PRINTS NCTRNSLOCATR UniProtKB/TrEMBL
PROSITE HLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013408 RatGTEx
SMART HLH UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
Superfamily-SCOP HLH_basic UniProtKB/TrEMBL
  SSF55785 UniProtKB/TrEMBL
UniProt B5DFA7 ENTREZGENE, UniProtKB/TrEMBL
  F1MAG2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Npas2  neuronal PAS domain protein 2   Npas2_predicted  neuronal PAS domain protein 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Npas2_predicted  neuronal PAS domain protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED