Bysl (bystin-like) - Rat Genome Database

Name: Bysl
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Bysl (bystin-like) Rattus norvegicus

Analyze

Symbol:

Bysl

Name:

bystin-like

RGD ID:

727959

Description:

Predicted to enable snoRNA binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to interleukin-1; and cellular response to lipopolysaccharide. Located in cell projection; cytoplasmic microtubule; and perinuclear region of cytoplasm. Orthologous to human BYSL (bystin like); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

bystin

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BYSL (bystin like)	RGD	RGD
Mus musculus (house mouse):	Bysl (bystin-like)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Bysl (bystin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BYSL (bystin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BYSL (bystin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Bysl (bystin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BYSL (bystin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BYSL (bystin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Bysl (bystin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	BYSL (bystin like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Bysl (bystin-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bysl (bystin-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ENP1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	byn-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	bys	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	13,382,806 - 13,392,557 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	13,382,557 - 13,394,339 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	21,962,562 - 21,972,307 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	9	27,026,687 - 27,036,467 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	9	25,325,963 - 25,335,708 (+)	NCBI	Rnor_WKY
Rnor_6.0	9	15,393,461 - 15,403,212 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	15,393,330 - 15,403,117 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	14,314,823 - 14,324,574 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	9	11,134,028 - 11,143,788 (+)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain Injuries (IEP)

genetic disease (ISO)

infantile Refsum disease (ISO)

Zellweger syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

4-amino-2,6-dinitrotoluene (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

ciguatoxin CTX1B (ISO)

coumarin (ISO)

cyclosporin A (ISO)

dioxygen (ISO)

elemental selenium (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

flutamide (EXP)

fulvestrant (ISO)

glafenine (EXP)

hexadecanoic acid (ISO)

ivermectin (ISO)

nefazodone (EXP)

nickel atom (ISO)

nimesulide (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

perfluorononanoic acid (ISO)

phenobarbital (ISO)

PhIP (EXP)

pirinixic acid (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

selenium atom (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

thapsigargin (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

Tributyltin oxide (ISO)

trimellitic anhydride (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blastocyst formation (ISO)

brain development (IEP)

cellular response to growth factor stimulus (IEP)

cellular response to interleukin-1 (IEP)

cellular response to lipopolysaccharide (IEP)

cellular response to organic cyclic compound (IEP)

in utero embryonic development (ISO)

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IEA,ISO)

rRNA processing (IBA)

stem cell proliferation (IEA,ISO)

trophectodermal cell differentiation (IEA,ISO)

Cellular Component

apical part of cell (IEA,ISO)

cell projection (IDA)

chromosome (IEA,ISO)

cytoplasm (IBA,IDA,IEA,ISO)

cytoplasmic microtubule (IDA)

intracellular membrane-bounded organelle (ISO)

nucleolus (IBA,IEA,ISO)

nucleoplasm (IEA,ISO)

perinuclear region of cytoplasm (IDA)

preribosome, small subunit precursor (IBA)

Molecular Function

molecular_function (ND)

protein binding (ISO)

snoRNA binding (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

ribosome biogenesis pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	An overview of pre-ribosomal RNA processing in eukaryotes.	Henras AK, etal., Wiley Interdiscip Rev RNA. 2015 Mar-Apr;6(2):225-42. doi: 10.1002/wrna.1269. Epub 2014 Oct 27.
3.	Expression of trophinin and bystin identifies distinct cell types in the germinal zones of adult rat brain.	Ma L, etal., Eur J Neurosci. 2006 May;23(9):2265-76.
4.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation
7.	Bystin as a novel marker for reactive astrocytes in the adult rat brain following injury.	Sheng J, etal., Eur J Neurosci. 2004 Aug;20(4):873-84.
8.	Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing.	Sloan KE, etal., J Cell Biol. 2013 Mar 4;200(5):577-88. doi: 10.1083/jcb.201207131. Epub 2013 Feb 25.
9.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10.	CK1delta and CK1epsilon are components of human 40S subunit precursors required for cytoplasmic 40S maturation.	Zemp I, etal., J Cell Sci. 2014 Mar 15;127(Pt 6):1242-53. doi: 10.1242/jcs.138719. Epub 2014 Jan 14.

Additional References at PubMed

PMID:17055491	PMID:17242206	PMID:19946888	PMID:22658674	PMID:26711351

Genomics

Comparative Map Data

Bysl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	13,382,806 - 13,392,557 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	13,382,557 - 13,394,339 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	21,962,562 - 21,972,307 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	9	27,026,687 - 27,036,467 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	9	25,325,963 - 25,335,708 (+)	NCBI	Rnor_WKY
Rnor_6.0	9	15,393,461 - 15,403,212 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	15,393,330 - 15,403,117 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	14,314,823 - 14,324,574 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	9	11,134,028 - 11,143,788 (+)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

BYSL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	41,908,759 - 41,933,046 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	6	41,921,499 - 41,933,046 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	41,889,237 - 41,900,784 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	41,996,943 - 42,008,762 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	41,996,942 - 42,008,760	NCBI
Celera	6	43,441,757 - 43,453,576 (+)	NCBI		Celera
Cytogenetic Map	6	p21.1	NCBI
HuRef	6	41,607,755 - 41,619,629 (+)	NCBI		HuRef
CHM1_1	6	41,891,723 - 41,903,544 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	41,750,059 - 41,761,606 (+)	NCBI		T2T-CHM13v2.0

Bysl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	47,910,256 - 47,922,417 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	47,910,256 - 47,922,417 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	47,599,331 - 47,611,492 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	47,599,331 - 47,611,492 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	47,736,280 - 47,748,441 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	47,063,271 - 47,074,675 (-)	NCBI		MGSCv36	mm8
Celera	17	51,036,357 - 51,048,455 (-)	NCBI		Celera
Cytogenetic Map	17	C	NCBI
cM Map	17	23.63	NCBI

Bysl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	8,257,081 - 8,266,875 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	8,257,081 - 8,266,627 (+)	NCBI	ChiLan1.0	ChiLan1.0

BYSL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	6	42,806,531 - 42,818,684 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	42,806,531 - 42,821,518 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	6	41,504,652 - 41,516,541 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

BYSL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	10,580,881 - 10,592,313 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	10,581,217 - 10,591,923 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	10,610,184 - 10,621,641 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	11,061,584 - 11,073,073 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	11,061,612 - 11,074,256 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	10,591,612 - 10,603,068 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	10,675,587 - 10,687,032 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	10,769,509 - 10,780,999 (+)	NCBI		UU_Cfam_GSD_1.0

Bysl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	46,063,609 - 46,073,118 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	17,888,335 - 17,896,268 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936476	17,887,998 - 17,896,598 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BYSL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	37,074,515 - 37,088,533 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	37,074,517 - 37,086,753 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	42,476,640 - 42,487,309 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BYSL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	30,230,001 - 30,241,684 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	30,230,337 - 30,241,417 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	41,921,109 - 41,933,105 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bysl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	17,195,251 - 17,205,198 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	17,195,248 - 17,204,827 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Bysl
72 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	50
Count of miRNA genes:	49
Interacting mature miRNAs:	50
Transcripts:	ENSRNOT00000075630
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10054141	Gmadr4	Adrenal mass QTL 4	2.45	0.0074	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	9	1	14209783	Rat
70226	Eae4	Experimental allergic encephalomyelitis QTL 4			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	9	1	25661317	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	1	37999212	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	1	37999212	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	1	37999212	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	40594091	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	1	43718459	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	1	43718459	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
1354650	Despr5	Despair related QTL 5	4.01	0.0017	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	9	1254084	46254084	Rat
2303559	Gluco54	Glucose level QTL 54	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	1254084	46254084	Rat
1578675	Bss17	Bone structure and strength QTL 17	3.8		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	9	3368652	13533896	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	5109826	42921101	Rat
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5109826	50109826	Rat
11353947	Bp392	Blood pressure QTL 392			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	7283252	52283252	Rat
61450	Ciaa3	CIA Autoantibody QTL 3	6.5		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	9	7954720	22071169	Rat
9589133	Insul26	Insulin level QTL 26	17.96	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	9	8952560	53952560	Rat
7411609	Foco16	Food consumption QTL 16	25.6	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	8952560	53952560	Rat

Markers in Region

BE107820

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	13,390,571 - 13,390,730 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	15,401,227 - 15,401,385	NCBI	Rnor6.0
Rnor_5.0	9	14,322,589 - 14,322,747	UniSTS	Rnor5.0
Celera	9	11,141,794 - 11,141,952	UniSTS
RH 3.4 Map	9	48.5	UniSTS

RH140270

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	13,392,226 - 13,392,432 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	15,402,882 - 15,403,087	NCBI	Rnor6.0
Rnor_5.0	9	14,324,244 - 14,324,449	UniSTS	Rnor5.0
Celera	9	11,143,458 - 11,143,663	UniSTS
RH 3.4 Map	9	46.9	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	35	38	27	18	27	1	4	66	27	39	11	1
Low		8	19	14	1	14	7	7	8	8	2		7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_182674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY257675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV104390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000075630 ⟹ ENSRNOP00000067656

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	13,382,557 - 13,394,339 (+)	Ensembl
Rnor_6.0 Ensembl	9	15,393,330 - 15,403,117 (+)	Ensembl

RefSeq Acc Id:

NM_182674 ⟹ NP_872615

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	13,382,806 - 13,392,557 (+)	NCBI
Rnor_6.0	9	15,393,461 - 15,403,212 (+)	NCBI
Rnor_5.0	9	14,314,823 - 14,324,574 (+)	NCBI
Celera	9	11,134,028 - 11,143,788 (+)	RGD

Sequence:

show sequence

GCAAGCGCAGTCTCGTCTCTTAGCCGGCTTCACACGTGTAAACTTTGTGGGCAAGTTTTTCGAC
AAAAATGCCCAAATTAAAGGTGACACGTGGGGCCAGAAATCAAGAGAGACATGCACCTCTGGCG
GAGCAGATTCTGGCTGGGGACGCAGTGCGTGCGGGGACCCGAGAAAAACGGCGGAGACACGGGG
TCGAAGAGGAGGAAGAGTATGTGGGACCCCGGTTGAGCAGACGGATTTTGCAACAAGCCCGGCA
GCAGCAGGAGGAGCTCGAGACTGAACACGCGACTGGAGATCGGCCGGCAAAACCGCGAGAGCGC
GCCACGCGGCTGGGGCCAGGAGTGCCACAGGATGGATCGGATGAGGAGGATGAGGAATGGCCTA
CCCTGGAGAAGGCAGCCAAAATGACCGTGGTGAACCACCAGGCAGAGGTAGTGGTGGACCCTGA
AGATGAACGCGCCATTGAAATGTTCATGAACAAGAACCCTCCTGTCAGGCGCACCCTGGCTGAC
ATCATCATGGAGAAGCTGACTGAGAAGCAGACAGAGGTGGAGACTGTCATGTCAGAAGTATCGG
GCTTCCCTATGCCTCAGCTGGATCCCCGGGTCCTGGAAGTCTACAGAGGAGTCCGGGAGGTGTT
ATGTAAATATCGCAGTGGGAAACTGCCCAAGGCTTTTAAGATCATCCCTGCCCTGTCCAACTGG
GAGCAGATCCTCTATGTCACGGAGCCCGAGGCCTGGACTGCAGCTGCCATGTATCAAGCCACCA
GGATTTTTGCCTCTAACCTGAAGGAGCGCATGGCTCAGCGCTTCTACAACCTTGTCCTGCTTCC
CCGAGTACGAGATGACATTGCTGAATACAAACGACTCAACTTCCACCTCTACATGGCACTCAAG
AAGGCCCTGTTCAAACCTGGAGCCTGGTTCAAAGGAATCCTGATCCCGCTGTGTGAGTCTGGCA
CCTGTACCCTCCGAGAAGCCATCATCGTGGGCAGCATCATCAGCAAGTGCTCCATCCCTGTGTT
GCACTCCAGTGCGGCCATGCTGAAGATCGCGGAGATGGAGTACAGTGGTGCCAGCAGCATCTTC
CTGCGCCTGCTGCTCGATAAGAAGTATGCACTGCCCTACCGGGTGCTCGACGCTCTGGTCTTCC
ATTTTCTGGCCTTCCGGACGGAGAAGCGCCAGCTGCCCGTGCTTTGGCACCAGTGCCTACTGAC
ACTAGCACAGCGCTACAAGGCTGACCTGGCCACGGAGCAGAAGGAGGCCCTCCTAGAACTGCTT
CGGCTGCAGCCCCACCCACAGCTATCCCCGGAAATCAGGCGTGAGCTTCAGAGTGCAGTCCCCA
GAGATGTGGAAGATGTTGTTGTCACCATGGAATGAGAACAGTCACCTGTGTTAGTCCAGGGGAT
GTGGGAGGACCCCAGCTGGTGTAGTTAAAGACCTAGTCAGGACACTGAAAGGTTACCGTGGCAT
CTGTGGCTCCAGTCTTGGGCAGGGAGGACTGCATCTGGTTGGCTTTCTCGCCAGTCCCTGCTCA
CTTCTGGAACCTAACTGGAGTCACCCCGGTTCAGTACCCCACAGCCCACCTGGCACCTGGTATG
AGGGCCGCTCTCTCCAGGTACTGTGTAAGCTCACTGGGTTTCGGATAAACCAGATTCAGTTATT
TATTGGAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_872615	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79030	(Get FASTA)	NCBI Sequence Viewer
	AAP22286	(Get FASTA)	NCBI Sequence Viewer
	EDM18889	(Get FASTA)	NCBI Sequence Viewer
	Q80WL2	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_872615 ⟸ NM_182674

- UniProtKB:

Q80WL2 (UniProtKB/Swiss-Prot), M0RDF7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPKLKVTRGARNQERHAPLAEQILAGDAVRAGTREKRRRHGVEEEEEYVGPRLSRRILQQARQQ
QEELETEHATGDRPAKPRERATRLGPGVPQDGSDEEDEEWPTLEKAAKMTVVNHQAEVVVDPED
ERAIEMFMNKNPPVRRTLADIIMEKLTEKQTEVETVMSEVSGFPMPQLDPRVLEVYRGVREVLC
KYRSGKLPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPR
VRDDIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIISKCSIPVLH
SSAAMLKIAEMEYSGASSIFLRLLLDKKYALPYRVLDALVFHFLAFRTEKRQLPVLWHQCLLTL
AQRYKADLATEQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVEDVVVTME

hide sequence

RefSeq Acc Id:

ENSRNOP00000067656 ⟸ ENSRNOT00000075630

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q80WL2-F1-model_v2	AlphaFold	Q80WL2	1-436	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696497

Promoter ID:

EPDNEW_R7021

Type:

multiple initiation site

Name:

Bysl_1

Description:

bystin-like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	15,393,463 - 15,393,523	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727959	AgrOrtholog
BioCyc Gene	G2FUF-28270	BioCyc
Ensembl Genes	ENSRNOG00000049121	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000067656	ENTREZGENE
	ENSRNOP00000067656.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000075630	ENTREZGENE
	ENSRNOT00000075630.3	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7114086	IMAGE-MGC_LOAD
InterPro	Bystin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:359727	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:93957	IMAGE-MGC_LOAD
NCBI Gene	359727	ENTREZGENE
PANTHER	BYSTIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR12821	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Bystin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	BYSL	RGD
PhenoGen	Bysl	PhenoGen
UniProt	BYST_RAT	UniProtKB/Swiss-Prot
	M0RDF7	ENTREZGENE, UniProtKB/TrEMBL
	Q80WL2	ENTREZGENE
UniProt Secondary	Q6AYI7	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-07-08	Bysl	bystin-like			Symbol and Name status set to approved	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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