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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Adgrb3 | Rat | 1,2-dichloroethane | decreases expression | ISO | Adgrb3 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of BAI3 mRNA | CTD | PMID:28960355 | Adgrb3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Adgrb3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ADGRB3 promoter] | CTD | PMID:19654925 | Adgrb3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ADGRB3 mRNA | CTD | PMID:32109520 | Adgrb3 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of ADGRB3 mRNA | CTD | PMID:32109520 | Adgrb3 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Adgrb3 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in decreased expression of ADGRB3 mRNA | CTD | PMID:18648102 | Adgrb3 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | ADGRB3 (Homo sapiens) | 6480464 | bisphenol S affects the methylation of ADGRB3 gene | CTD | PMID:31601247 | Adgrb3 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ADGRB3 mRNA | CTD | PMID:24780913 | Adgrb3 | Rat | aristolochic acid A | decreases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ADGRB3 mRNA | CTD | PMID:33212167 | Adgrb3 | Rat | atrazine | decreases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of ADGRB3 mRNA | CTD | PMID:22378314 | Adgrb3 | Rat | benzene | increases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | Benzene results in increased expression of ADGRB3 mRNA | CTD | PMID:20036648 | Adgrb3 | Rat | benzo[a]pyrene | affects methylation | ISO | ADGRB3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ADGRB3 5' UTR; Benzo(a)pyrene affects the methylation of ADGRB3 promoter | CTD | PMID:27901495 | Adgrb3 | Rat | benzo[a]pyrene | decreases methylation | ISO | Adgrb3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of ADGRB3 intron | CTD | PMID:27901495 | Adgrb3 | Rat | benzo[a]pyrene | increases methylation | ISO | ADGRB3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ADGRB3 exon | CTD | PMID:27901495 | Adgrb3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ADGRB3 mRNA | CTD | PMID:25181051 | Adgrb3 | Rat | bisphenol A | decreases expression | ISO | Adgrb3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ADGRB3 mRNA | CTD | PMID:32156529 | Adgrb3 | Rat | bisphenol A | increases methylation | ISO | ADGRB3 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of ADGRB3 gene | CTD | PMID:31601247 | Adgrb3 | Rat | bisphenol F | decreases expression | ISO | Adgrb3 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of ADGRB3 mRNA | CTD | PMID:30951980 | Adgrb3 | Rat | cyclosporin A | decreases methylation | ISO | ADGRB3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of ADGRB3 promoter | CTD | PMID:27989131 | Adgrb3 | Rat | cytarabine | increases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | Cytarabine results in increased expression of ADGRB3 mRNA | CTD | PMID:21198554 | Adgrb3 | Rat | diallyl disulfide | multiple interactions | ISO | ADGRB3 (Homo sapiens) | 6480464 | diallyl disulfide inhibits the reaction [tobacco tar analog results in increased expression of ADGRB3 mRNA] | CTD | PMID:36758788 | Adgrb3 | Rat | diethylstilbestrol | decreases expression | EXP | | 6480464 | Diethylstilbestrol results in decreased expression of ADGRB3 mRNA | CTD | PMID:17005392 | Adgrb3 | Rat | dorsomorphin | multiple interactions | ISO | ADGRB3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Adgrb3 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of ADGRB3 mRNA | CTD | PMID:30307764 | Adgrb3 | Rat | genistein | increases expression | ISO | Adgrb3 (Mus musculus) | 6480464 | Genistein results in increased expression of BAI3 mRNA | CTD | PMID:32186404 | Adgrb3 | Rat | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB3 mRNA | CTD | PMID:22129741 | Adgrb3 | Rat | lithium chloride | increases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | Lithium Chloride results in increased expression of ADGRB3 mRNA | CTD | PMID:15711924 | Adgrb3 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of ADGRB3 gene | CTD | PMID:33148267 | Adgrb3 | Rat | N-acetyl-L-cysteine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB3 mRNA | CTD | PMID:22129741 | Adgrb3 | Rat | N-methyl-4-phenylpyridinium | decreases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of ADGRB3 mRNA | CTD | PMID:24810058 | Adgrb3 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB3 mRNA | CTD | PMID:22129741 | Adgrb3 | Rat | okadaic acid | decreases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of ADGRB3 mRNA | CTD | PMID:38832940 | Adgrb3 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of ADGRB3 gene | CTD | PMID:33148267 | Adgrb3 | Rat | phenytoin | increases expression | EXP | | 6480464 | Phenytoin results in increased expression of ADGRB3 mRNA | CTD | PMID:20345932 | Adgrb3 | Rat | rotenone | decreases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of ADGRB3 mRNA | CTD | PMID:29955902 | Adgrb3 | Rat | SB 431542 | multiple interactions | ISO | ADGRB3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Adgrb3 | Rat | sodium arsenite | decreases methylation | ISO | Adgrb3 (Mus musculus) | 6480464 | sodium arsenite results in decreased methylation of BAI3 gene | CTD | PMID:32068019 | Adgrb3 | Rat | sodium arsenite | increases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ADGRB3 mRNA | CTD | PMID:38568856 | Adgrb3 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of ADGRB3 mRNA | CTD | PMID:19281266 | Adgrb3 | Rat | titanium dioxide | decreases methylation | ISO | Adgrb3 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of BAI3 promoter | CTD | PMID:35295148 | Adgrb3 | Rat | titanium dioxide | increases methylation | ISO | Adgrb3 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of BAI3 promoter | CTD | PMID:35295148 | Adgrb3 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of ADGRB3 mRNA | CTD | PMID:33387578 | Adgrb3 | Rat | trichostatin A | increases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ADGRB3 mRNA | CTD | PMID:24935251 | Adgrb3 | Rat | valproic acid | increases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ADGRB3 mRNA | CTD | PMID:23179753|PMID:24383497|PMID:24935251|PMID:26272509|PMID:28001369 | Adgrb3 | Rat | valproic acid | multiple interactions | ISO | ADGRB3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Adgrb3 | Rat | vorinostat | decreases expression | ISO | ADGRB3 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of ADGRB3 mRNA | CTD | PMID:27188386 | |