Nck2 (NCK adaptor protein 2) - Rat Genome Database

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Gene: Nck2 (NCK adaptor protein 2) Rattus norvegicus
Analyze
Symbol: Nck2
Name: NCK adaptor protein 2
RGD ID: 1305965
Description: Predicted to enable several functions, including phosphotyrosine residue binding activity; receptor tyrosine kinase binding activity; and scaffold protein binding activity. Acts upstream of or within dendritic spine development and immunological synapse formation. Located in postsynaptic density. Orthologous to human NCK2 (NCK adaptor protein 2); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; insulin signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cytoplasmic protein NCK2; LOC316369; non-catalytic region of tyrosine kinase adaptor protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8953,206,006 - 53,332,417 (+)NCBIGRCr8
mRatBN7.2945,713,979 - 45,840,330 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl945,714,883 - 45,840,307 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx954,216,238 - 54,348,337 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0959,339,036 - 59,471,142 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0957,619,256 - 57,751,368 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0950,246,767 - 50,373,307 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl950,247,692 - 50,373,284 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0949,914,483 - 50,040,945 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4942,650,261 - 42,776,967 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1942,651,481 - 42,778,381 (+)NCBI
Celera943,431,256 - 43,557,014 (+)NCBICelera
Cytogenetic Map9q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. ILK, PINCH and parvin: the tIPP of integrin signalling. Legate KR, etal., Nat Rev Mol Cell Biol. 2006 Jan;7(1):20-31.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Segura I, etal., Nat Neurosci. 2007 Mar;10(3):301-10. Epub 2007 Feb 18.
Additional References at PubMed
PMID:10026169   PMID:12091389   PMID:12110186   PMID:12147689   PMID:12637565   PMID:12808099   PMID:14676213   PMID:16511561   PMID:16835242   PMID:17591694   PMID:20624904   PMID:25468996  


Genomics

Comparative Map Data
Nck2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8953,206,006 - 53,332,417 (+)NCBIGRCr8
mRatBN7.2945,713,979 - 45,840,330 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl945,714,883 - 45,840,307 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx954,216,238 - 54,348,337 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0959,339,036 - 59,471,142 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0957,619,256 - 57,751,368 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0950,246,767 - 50,373,307 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl950,247,692 - 50,373,284 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0949,914,483 - 50,040,945 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4942,650,261 - 42,776,967 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1942,651,481 - 42,778,381 (+)NCBI
Celera943,431,256 - 43,557,014 (+)NCBICelera
Cytogenetic Map9q22NCBI
NCK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382105,744,453 - 105,894,272 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2105,744,912 - 105,894,274 (+)EnsemblGRCh38hg38GRCh38
GRCh372106,361,369 - 106,510,728 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362105,727,786 - 105,877,160 (+)NCBINCBI36Build 36hg18NCBI36
Build 342105,819,871 - 105,969,244NCBI
Celera2100,633,297 - 100,711,182 (+)NCBICelera
Cytogenetic Map2q12.2NCBI
HuRef2100,201,822 - 100,279,928 (+)NCBIHuRef
CHM1_12106,365,834 - 106,515,058 (+)NCBICHM1_1
T2T-CHM13v2.02106,205,667 - 106,355,582 (+)NCBIT2T-CHM13v2.0
Nck2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39143,484,643 - 43,609,678 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl143,483,739 - 43,609,675 (+)EnsemblGRCm39 Ensembl
GRCm38143,445,483 - 43,570,518 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl143,444,579 - 43,570,515 (+)EnsemblGRCm38mm10GRCm38
MGSCv37143,502,596 - 43,627,363 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36143,390,297 - 43,515,060 (+)NCBIMGSCv36mm8
Celera143,789,420 - 43,915,515 (+)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map123.18NCBI
Nck2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547010,487,481 - 10,593,046 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547010,487,962 - 10,593,046 (+)NCBIChiLan1.0ChiLan1.0
NCK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,826,888 - 21,977,466 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A21,829,652 - 21,980,231 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A95,939,197 - 96,089,163 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A106,827,621 - 106,976,362 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A106,898,547 - 106,976,363 (+)Ensemblpanpan1.1panPan2
NCK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11037,584,351 - 37,734,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1037,585,565 - 37,732,994 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1037,509,022 - 37,661,002 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01038,434,612 - 38,590,460 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1038,434,614 - 38,588,705 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11038,166,351 - 38,316,130 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01038,443,073 - 38,594,964 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01038,636,761 - 38,787,028 (-)NCBIUU_Cfam_GSD_1.0
Nck2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629286,718,210 - 86,762,553 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936764140,946 - 185,529 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936764141,159 - 185,482 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl349,063,991 - 49,198,664 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1349,063,813 - 49,222,274 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2351,391,130 - 51,413,769 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NCK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1149,412,677 - 9,515,565 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl149,437,301 - 9,515,561 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041177,084,239 - 177,234,654 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nck2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247499,765,308 - 9,884,472 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nck2
623 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:176
Count of miRNA genes:114
Interacting mature miRNAs:151
Transcripts:ENSRNOT00000023029
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat

Markers in Region
RH137411  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2945,764,811 - 45,765,031 (+)MAPPERmRatBN7.2
Rnor_6.0950,297,618 - 50,297,837NCBIRnor6.0
Rnor_5.0949,965,168 - 49,965,387UniSTSRnor5.0
RGSC_v3.4942,700,162 - 42,700,381UniSTSRGSC3.4
Celera943,481,111 - 43,481,330UniSTS
RH 3.4 Map9397.7UniSTS
Cytogenetic Map9q22UniSTS
BE107300  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2945,829,158 - 45,829,355 (+)MAPPERmRatBN7.2
Rnor_6.0950,362,134 - 50,362,330NCBIRnor6.0
Rnor_5.0950,029,772 - 50,029,968UniSTSRnor5.0
RGSC_v3.4942,765,800 - 42,765,996UniSTSRGSC3.4
Celera943,545,847 - 43,546,043UniSTS
RH 3.4 Map9397.3UniSTS
Cytogenetic Map9q22UniSTS
AF043260  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2945,839,171 - 45,839,296 (+)MAPPERmRatBN7.2
Rnor_6.0950,372,149 - 50,372,273NCBIRnor6.0
Rnor_5.0950,039,787 - 50,039,911UniSTSRnor5.0
RGSC_v3.4942,775,813 - 42,775,937UniSTSRGSC3.4
Celera943,555,860 - 43,555,984UniSTS
Cytogenetic Map9q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 32 39 24 19 24 8 11 74 35 40 11 8
Low 11 18 17 17 1
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000023029   ⟹   ENSRNOP00000023029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl945,714,883 - 45,840,307 (+)Ensembl
Rnor_6.0 Ensembl950,247,692 - 50,373,284 (+)Ensembl
RefSeq Acc Id: NM_001108216   ⟹   NP_001101686
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8953,206,979 - 53,332,413 (+)NCBI
mRatBN7.2945,714,883 - 45,840,326 (+)NCBI
Rnor_6.0950,247,692 - 50,373,303 (+)NCBI
Rnor_5.0949,914,483 - 50,040,945 (+)NCBI
RGSC_v3.4942,650,261 - 42,776,967 (+)RGD
Celera943,431,256 - 43,557,014 (+)RGD
Sequence:
RefSeq Acc Id: XM_006244825   ⟹   XP_006244887
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8953,206,006 - 53,332,417 (+)NCBI
mRatBN7.2945,713,979 - 45,840,330 (+)NCBI
Rnor_6.0950,246,767 - 50,373,307 (+)NCBI
Rnor_5.0949,914,483 - 50,040,945 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008767035   ⟹   XP_008765257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8953,231,424 - 53,332,417 (+)NCBI
mRatBN7.2945,739,464 - 45,840,330 (+)NCBI
Rnor_6.0950,270,393 - 50,373,307 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063267163   ⟹   XP_063123233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8953,206,481 - 53,332,417 (+)NCBI
RefSeq Acc Id: XM_063267164   ⟹   XP_063123234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8953,206,028 - 53,332,417 (+)NCBI
RefSeq Acc Id: NP_001101686   ⟸   NM_001108216
- UniProtKB: D4A3M8 (UniProtKB/TrEMBL),   A6INR5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244887   ⟸   XM_006244825
- Peptide Label: isoform X1
- UniProtKB: D4A3M8 (UniProtKB/TrEMBL),   A6INR5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765257   ⟸   XM_008767035
- Peptide Label: isoform X1
- UniProtKB: D4A3M8 (UniProtKB/TrEMBL),   A6INR5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000023029   ⟸   ENSRNOT00000023029
RefSeq Acc Id: XP_063123234   ⟸   XM_063267164
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063123233   ⟸   XM_063267163
- Peptide Label: isoform X1
Protein Domains
SH2   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3M8-F1-model_v2 AlphaFold D4A3M8 1-380 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696640
Promoter ID:EPDNEW_R7165
Type:single initiation site
Name:Nck2_1
Description:NCK adaptor protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0950,247,712 - 50,247,772EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305965 AgrOrtholog
BioCyc Gene G2FUF-27667 BioCyc
Ensembl Genes ENSRNOG00000017155 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000023029 ENTREZGENE
  ENSRNOT00000023029.8 UniProtKB/TrEMBL
Gene3D-CATH 3.30.505.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro Cytoplasmic_NCK UniProtKB/TrEMBL
  Nck2_SH2 UniProtKB/TrEMBL
  Nck2_SH3_1 UniProtKB/TrEMBL
  Nck2_SH3_2 UniProtKB/TrEMBL
  Nck2_SH3_3 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
KEGG Report rno:316369 UniProtKB/TrEMBL
NCBI Gene 316369 ENTREZGENE
PANTHER PTHR19969:SF12 UniProtKB/TrEMBL
  SH2-SH3 ADAPTOR PROTEIN-RELATED UniProtKB/TrEMBL
Pfam SH2 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PhenoGen Nck2 PhenoGen
PIRSF Cytoplasmic_NCK UniProtKB/TrEMBL
PRINTS SH2DOMAIN UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017155 RatGTEx
SMART SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SH3 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A6INR5 ENTREZGENE, UniProtKB/TrEMBL
  D4A3M8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-09 Nck2  NCK adaptor protein 2  Nck2  non-catalytic region of tyrosine kinase adaptor protein 2   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Nck2  non-catalytic region of tyrosine kinase adaptor protein 2   Nck2_predicted  non-catalytic region of tyrosine kinase adaptor protein 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Nck2_predicted  non-catalytic region of tyrosine kinase adaptor protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED