Cox5b (cytochrome c oxidase subunit 5B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cox5b (cytochrome c oxidase subunit 5B) Rattus norvegicus
Analyze
Symbol: Cox5b
Name: cytochrome c oxidase subunit 5B
RGD ID: 620608
Description: Predicted to enable cytochrome-c oxidase activity. Involved in response to peptide hormone and response to thyroid hormone. Predicted to be located in mitochondrial membrane. Predicted to be part of respiratory chain complex IV. Biomarker of hypertension. Orthologous to human COX5B (cytochrome c oxidase subunit 5B); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cytochrome c oxidase polypeptide Vb; cytochrome c oxidase subunit 5B, mitochondrial; cytochrome c oxidase subunit Vb; cytochrome c oxidase subunit VIA*
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Cox5b-ps2  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8946,417,735 - 46,419,664 (+)NCBIGRCr8
mRatBN7.2938,921,980 - 38,923,806 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl938,921,967 - 38,925,052 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx947,425,120 - 47,426,948 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0952,540,773 - 52,542,599 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0950,822,671 - 50,824,497 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0943,259,706 - 43,262,039 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl943,259,709 - 43,262,040 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0942,912,214 - 42,914,547 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4935,625,478 - 35,627,304 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1935,626,891 - 35,628,718 (+)NCBI
Celera936,688,358 - 36,690,184 (+)NCBICelera
Cytogenetic Map9q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (EXP)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
astaxanthin  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
Brodifacoum  (EXP)
cadmium acetate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chloropicrin  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
crocidolite asbestos  (ISO)
D-glucose  (EXP)
deoxynivalenol  (ISO)
dextran sulfate  (ISO)
dicrotophos  (ISO)
dioxygen  (EXP)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
genistein  (EXP)
glafenine  (EXP)
glucose  (EXP)
glyphosate  (ISO)
graphite  (ISO)
heptachlor  (EXP)
homocysteine  (ISO)
hydrogen peroxide  (ISO)
isoniazide  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lamivudine  (ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methylparaben  (ISO)
myricetin  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (ISO)
ochratoxin A  (EXP,ISO)
ozone  (ISO)
paraquat  (EXP)
perfluorododecanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
Pyridostigmine bromide  (EXP)
quercetin  (EXP)
resveratrol  (ISO)
rotenone  (EXP,ISO)
sarin  (EXP)
SB 431542  (ISO)
scopolamine  (EXP)
streptozocin  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
tetrathiomolybdate(2-)  (ISO)
thapsigargin  (EXP)
theophylline  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Nucleotide sequence of cDNA for rat liver and brain cytochrome c oxidase subunit VIa (Vb). Goto Y, etal., Nucleic Acids Res 1989 Aug 11;17(15):6388.
4. Molecular cloning and characterization of the rat cytochrome c oxidase subunit Vb gene. Hoshinaga H, etal., J Biochem (Tokyo) 1994 Feb;115(2):194-201.
5. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
6. The profile of cardiac cytochrome c oxidase (COX) expression in an accelerated cardiac-hypertrophy model. Kuo WW, etal., J Biomed Sci. 2005;12(4):601-10. Epub 2005 Nov 10.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Tissue-specific regulation of cytochrome c oxidase subunit expression by thyroid hormone. Sheehan TE, etal., Am J Physiol Endocrinol Metab 2004 Jun;286(6):E968-74. Epub 2004 Feb 17.
14. Precursor peptide progastrin(1-80) reduces apoptosis of intestinal epithelial cells and upregulates cytochrome c oxidase Vb levels and synthesis of ATP. Wu H, etal., Am J Physiol Gastrointest Liver Physiol. 2003 Dec;285(6):G1097-110. Epub 2003 Jul 24.
Additional References at PubMed
PMID:7601105   PMID:12477932   PMID:12865426   PMID:14645204   PMID:14651853   PMID:15489334   PMID:16103131   PMID:17634366   PMID:18408135   PMID:18614015   PMID:23376485   PMID:25002582  
PMID:26316108   PMID:28246552   PMID:29476059   PMID:30030519   PMID:30361391  


Genomics

Comparative Map Data
Cox5b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8946,417,735 - 46,419,664 (+)NCBIGRCr8
mRatBN7.2938,921,980 - 38,923,806 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl938,921,967 - 38,925,052 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx947,425,120 - 47,426,948 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0952,540,773 - 52,542,599 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0950,822,671 - 50,824,497 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0943,259,706 - 43,262,039 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl943,259,709 - 43,262,040 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0942,912,214 - 42,914,547 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4935,625,478 - 35,627,304 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1935,626,891 - 35,628,718 (+)NCBI
Celera936,688,358 - 36,690,184 (+)NCBICelera
Cytogenetic Map9q21NCBI
COX5B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38297,646,062 - 97,648,383 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl297,646,062 - 97,648,383 (+)EnsemblGRCh38hg38GRCh38
GRCh37298,262,525 - 98,264,846 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36297,628,953 - 97,631,089 (+)NCBINCBI36Build 36hg18NCBI36
Build 34297,721,038 - 97,723,174NCBI
Celera292,466,522 - 92,468,658 (+)NCBICelera
Cytogenetic Map2q11.2ENTREZGENE
HuRef292,028,218 - 92,030,354 (+)NCBIHuRef
CHM1_1298,266,878 - 98,269,014 (+)NCBICHM1_1
T2T-CHM13v2.0298,104,283 - 98,106,604 (+)NCBIT2T-CHM13v2.0
Cox5b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39136,730,568 - 36,732,469 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl136,730,530 - 36,732,762 (+)EnsemblGRCm39 Ensembl
GRCm38136,691,487 - 36,693,388 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl136,691,449 - 36,693,681 (+)EnsemblGRCm38mm10GRCm38
MGSCv37136,748,332 - 36,750,233 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36136,636,084 - 36,637,931 (+)NCBIMGSCv36mm8
Celera136,478,001 - 36,479,902 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map115.38NCBI
LOC102024993
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554704,321,555 - 4,324,824 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554704,321,555 - 4,323,449 (+)NCBIChiLan1.0ChiLan1.0
LOC100972878
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21230,807,917 - 30,810,670 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A30,810,678 - 30,813,320 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A101,675,232 - 101,677,417 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A98,544,980 - 98,547,502 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A98,544,980 - 98,547,502 (+)Ensemblpanpan1.1panPan2
COX5B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11044,979,654 - 44,991,620 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1044,979,654 - 44,991,703 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1044,906,755 - 44,912,985 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01045,855,804 - 45,867,780 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1045,855,801 - 45,862,133 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11045,567,657 - 45,573,888 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01045,853,736 - 45,859,974 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01046,037,104 - 46,043,336 (-)NCBIUU_Cfam_GSD_1.0
LOC101965209
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629283,669,097 - 83,670,860 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936744921,888 - 923,803 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COX5B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl356,629,272 - 56,632,119 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1356,630,297 - 56,632,107 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2359,376,451 - 59,378,263 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COX5B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1141,331,853 - 1,334,144 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041168,772,779 - 168,775,319 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101714602
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247492,837,078 - 2,840,048 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247492,837,030 - 2,838,880 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cox5b
6 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:57
Count of miRNA genes:53
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000022487
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat

Markers in Region
PMC195978P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2938,921,674 - 38,921,935 (+)MAPPERmRatBN7.2
Rnor_6.0943,259,401 - 43,259,661NCBIRnor6.0
Rnor_5.0942,911,909 - 42,912,169UniSTSRnor5.0
RGSC_v3.4935,625,173 - 35,625,433UniSTSRGSC3.4
Celera936,688,053 - 36,688,313UniSTS
Cytogenetic Map9q21UniSTS
Cox5b  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera2029,401,613 - 29,401,809UniSTS
Celera936,689,013 - 36,690,028UniSTS
Cytogenetic Map9q21UniSTS
Cytogenetic Map20q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC083179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D10951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D10952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X14208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000022487   ⟹   ENSRNOP00000022487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl938,921,967 - 38,925,052 (+)Ensembl
Rnor_6.0 Ensembl943,259,709 - 43,262,040 (+)Ensembl
RefSeq Acc Id: NM_053586   ⟹   NP_446038
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,417,837 - 46,419,663 (+)NCBI
mRatBN7.2938,921,980 - 38,923,806 (+)NCBI
Rnor_6.0943,259,706 - 43,262,039 (+)NCBI
Rnor_5.0942,912,214 - 42,914,547 (+)NCBI
RGSC_v3.4935,625,478 - 35,627,304 (+)RGD
Celera936,688,358 - 36,690,184 (+)RGD
Sequence:
RefSeq Acc Id: XM_063267789   ⟹   XP_063123859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,417,735 - 46,419,664 (+)NCBI
RefSeq Acc Id: NP_446038   ⟸   NM_053586
- Peptide Label: precursor
- UniProtKB: P12075 (UniProtKB/Swiss-Prot),   A6INE7 (UniProtKB/TrEMBL),   A0A8L2QBW2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022487   ⟸   ENSRNOT00000022487
RefSeq Acc Id: XP_063123859   ⟸   XM_063267789
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P12075-F1-model_v2 AlphaFold P12075 1-129 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696608
Promoter ID:EPDNEW_R7133
Type:initiation region
Name:Cox5b_1
Description:cytochrome c oxidase subunit 5B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0943,259,706 - 43,259,766EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620608 AgrOrtholog
BioCyc Gene G2FUF-27801 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
  PWY-7279 BioCyc
Ensembl Genes ENSRNOG00000016660 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022487.6 UniProtKB/TrEMBL
Gene3D-CATH 2.60.11.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7300877 IMAGE-MGC_LOAD
InterPro Cyt_c_oxidase_su5b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_c_oxidase_su5b_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94194 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:105368 IMAGE-MGC_LOAD
NCBI Gene 94194 ENTREZGENE
PANTHER CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10122 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COX5B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cox5b PhenoGen
PROSITE COX5B_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  COX5B_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016660 RatGTEx
Superfamily-SCOP Rubredoxin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2QBW2 ENTREZGENE, UniProtKB/TrEMBL
  A6INE6_RAT UniProtKB/TrEMBL
  A6INE7 ENTREZGENE, UniProtKB/TrEMBL
  A6INE8_RAT UniProtKB/TrEMBL
  A6INE9_RAT UniProtKB/TrEMBL
  COX5B_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Cox5b  cytochrome c oxidase subunit 5B  Cox5b  cytochrome c oxidase subunit Vb  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Cox5b  cytochrome c oxidase subunit Vb      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Cox5b  cytochrome c oxidase subunit Vb      Symbol and Name status set to provisional 70820 PROVISIONAL