 Gene Ontology Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Function
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Analyze GeneStrainQTL List |
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Variant Visualizer (Genomic Variants) |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Molecular Function
Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Molecular Function
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References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | RGD automated data pipeline |
| 3. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Tbc1d8 (Rattus norvegicus - Norway rat) |
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| TBC1D8 (Homo sapiens - human) |
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| Tbc1d8 (Mus musculus - house mouse) |
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| Tbc1d8 (Chinchilla lanigera - long-tailed chinchilla) |
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| TBC1D8 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| TBC1D8 (Canis lupus familiaris - dog) |
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| Tbc1d8 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| TBC1D8 (Sus scrofa - pig) |
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Position Markers| RH143784 |
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| BE108075 |
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| RH127697 |
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| BE118306 |
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| TBC1D8 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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| High | ||||||||||||||||
| Medium | 3 | 6 | 3 | 4 | 2 | 6 | 11 | 11 | 5 | 5 | ||||||
| Low | 19 | 37 | 23 | 12 | 3 | 1 | 8 | 26 | 19 | 41 | 35 | 3 | 3 | |||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001191067 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006244851 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07067444 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07067445 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07067446 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07067447 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059505 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059506 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059507 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059508 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059509 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059510 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | NM_001191067 ⟹ NP_001177996 | |||||||||||||||||||
| RefSeq Status: | INFERRED | |||||||||||||||||||
| Type: | CODING | |||||||||||||||||||
| Position: |
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| Sequence: |
GGCAGCGCGGGGTGATCCCGGCGAGCTGTGGTCTTGGCGCTCTGGGGCTAGGCAGGCGCTCCCGhide sequence |
| RefSeq Acc Id: | XM_006244851 ⟹ XP_006244913 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
CTGGGGCGGGGCCACGGCGGGCAGCGCGGGGTGATCCCGGCGAGCTGTGGTCTTGGCGCTCTGGhide sequence |
Protein Sequences| Protein RefSeqs | NP_001177996 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006244913 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_001177996 ⟸ NM_001191067 |
| - UniProtKB: | F1LWZ7 (UniProtKB/TrEMBL) |
| - Sequence: |
MWLKPEEVLLKNALKLWVTQKSSCYFVLQRRRGHGEGGGRLTGRLVGALDAVLDSSARVAPFRIhide sequence |
| RefSeq Acc Id: | XP_006244913 ⟸ XM_006244851 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MWLKPEEVLLKNALKLWVTQKSSCYFVLQRRRGHGEGGGRLTGRLVGALDAVLDSSARVAPFRIhide sequence |
TranscriptomePromoters| RGD ID: | 13696625 | |||||||||
| Promoter ID: | EPDNEW_R7149 | |||||||||
| Type: | multiple initiation site | |||||||||
| Name: | Tbc1d8_1 | |||||||||
| Description: | TBC1 domain family, member 8 | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1595491 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000013583 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000018640 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000018640 | ENTREZGENE, UniProtKB/TrEMBL |
| Gene3D-CATH | 2.30.29.30 | UniProtKB/TrEMBL |
| InterPro | EF-hand-like_dom | UniProtKB/TrEMBL |
| EF_hand_Ca-bd | UniProtKB/TrEMBL | |
| GRAM | UniProtKB/TrEMBL | |
| PH-like_dom_sf | UniProtKB/TrEMBL | |
| Rab-GTPase_TBC_sf | UniProtKB/TrEMBL | |
| RabGAP/TBC_dom | UniProtKB/TrEMBL | |
| TBC1D8_PH-GRAM1 | UniProtKB/TrEMBL | |
| TBC1D8_PH-GRAM2 | UniProtKB/TrEMBL | |
| KEGG Report | rno:680133 | UniProtKB/TrEMBL |
| NCBI Gene | 680133 | ENTREZGENE |
| Pfam | GRAM | UniProtKB/TrEMBL |
| TBC | UniProtKB/TrEMBL | |
| PhenoGen | Tbc1d8 | PhenoGen |
| PROSITE | EF_HAND_2 | UniProtKB/TrEMBL |
| TBC_RABGAP | UniProtKB/TrEMBL | |
| SMART | GRAM | UniProtKB/TrEMBL |
| TBC | UniProtKB/TrEMBL | |
| Superfamily-SCOP | RabGAP_TBC | UniProtKB/TrEMBL |
| SSF47473 | UniProtKB/TrEMBL | |
| UniGene | Rn.205305 | ENTREZGENE |
| UniProt | F1LWZ7 | ENTREZGENE, UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2013-05-24 | Tbc1d8 | TBC1 domain family, member 8 | LOC100364476 | rCG22278-like | Data Merged | 1643240 | APPROVED |
| 2010-05-05 | LOC100364476 | rCG22278-like | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2010-04-21 | Tbc1d8 | TBC1 domain family, member 8 | LOC680133 | similar to TBC1 domain family, member 8 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-01-09 | LOC680133 | similar to TBC1 domain family, member 8 | LOC681648 | similar to TBC1 domain family, member 8 | Data Merged | 1643240 | APPROVED |
| 2006-11-20 | LOC680133 | similar to TBC1 domain family, member 8 | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2006-11-20 | LOC681648 | similar to TBC1 domain family, member 8 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
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| More on Tbc1d8 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1595491 |
| Created: | 2006-11-20 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-11-27 |
| Status: | ACTIVE |
