![]() |
Molecular Function
![]() |
Create Name: | |
Description: |
![]() |
Save what matters to you |
{{ loginError }} |
Sign in with your RGD account |
Create New Account | Recover Password |
Analyze GeneStrainQTL List |
![]() Gene Annotator (Functional Annotation) unavailable |
![]() Gene Annotator (Annotation Distribution) unavailable |
![]() Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
![]() InterViewer (Protein-Protein Interactions) unavailable |
![]() Gviewer (Genome Viewer) unavailable |
![]() Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
![]() Gene Annotator (Annotation Comparison) unavailable |
![]() OLGA (Gene List Generator) unavailable |
![]() |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
![]() MOET (Multi-Ontology Enrichement) unavailable |
![]() GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
![]() Biological Process Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | activation of GTPase activity | | IBA | PANTHER:PTN000537561 more ... | 13792537 | PMID:21873635 | GO_Central | | intracellular protein transport | | IBA | MGI:MGI:2385326, PANTHER:PTN000537561 | 13792537 | PMID:21873635 | GO_Central | | intracellular protein transport | | IBA | MGI:MGI:2385326 more ... | 13792537 | PMID:21873635 | GO_Central | | regulation of cilium assembly | NOT | ISO | RGD:1347118 | 1624291 | (PMID:17646400) | RGD | PMID:17646400 | |
|
|
|
|
|
|
|
1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | RGD automated data pipeline |
3. | RGD automated import pipeline for gene-chemical interactions |
Tbc1d8 (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
TBC1D8 (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tbc1d8 (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tbc1d8 (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
TBC1D8 (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
TBC1D8 (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tbc1d8 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
TBC1D8 (Sus scrofa - pig) |
|
RH143784 |
|
|||||||||||||||||||||||||||||||||||
BE108075 |
|
|||||||||||||||||||||||||||||||||||
RH127697 |
|
|||||||||||||||||||||||||||||||||||
BE118306 |
|
|||||||||||||||||||||||||||||||||||
TBC1D8 |
|
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High | ||||||||||||||||
Medium | 3 | 6 | 3 | 4 | 2 | 6 | 11 | 11 | 5 | 5 | ||||||
Low | 19 | 37 | 23 | 12 | 3 | 1 | 8 | 26 | 19 | 41 | 35 | 3 | 3 | |||
Below cutoff |
RefSeq Transcripts | NM_001191067 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006244851 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AABR07067444 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AABR07067445 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AABR07067446 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AABR07067447 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01059505 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01059506 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01059507 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01059508 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01059509 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01059510 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | NM_001191067 ⟹ NP_001177996 | |||||||||||||||||||
RefSeq Status: | INFERRED | |||||||||||||||||||
Type: | CODING | |||||||||||||||||||
Position: |
|
|||||||||||||||||||
Sequence: |
GGCAGCGCGGGGTGATCCCGGCGAGCTGTGGTCTTGGCGCTCTGGGGCTAGGCAGGCGCTCCCGhide sequence |
RefSeq Acc Id: | XM_006244851 ⟹ XP_006244913 | ||||||||||||||
RefSeq Status: | |||||||||||||||
Type: | CODING | ||||||||||||||
Position: |
|
||||||||||||||
Sequence: |
CTGGGGCGGGGCCACGGCGGGCAGCGCGGGGTGATCCCGGCGAGCTGTGGTCTTGGCGCTCTGGhide sequence |
Protein RefSeqs | NP_001177996 | (Get FASTA) | NCBI Sequence Viewer |
XP_006244913 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001177996 ⟸ NM_001191067 |
- UniProtKB: | F1LWZ7 (UniProtKB/TrEMBL) |
- Sequence: |
MWLKPEEVLLKNALKLWVTQKSSCYFVLQRRRGHGEGGGRLTGRLVGALDAVLDSSARVAPFRIhide sequence |
RefSeq Acc Id: | XP_006244913 ⟸ XM_006244851 |
- Peptide Label: | isoform X1 |
- Sequence: |
MWLKPEEVLLKNALKLWVTQKSSCYFVLQRRRGHGEGGGRLTGRLVGALDAVLDSSARVAPFRIhide sequence |
RGD ID: | 13696625 | |||||||||
Promoter ID: | EPDNEW_R7149 | |||||||||
Type: | multiple initiation site | |||||||||
Name: | Tbc1d8_1 | |||||||||
Description: | TBC1 domain family, member 8 | |||||||||
SO ACC ID: | SO:0000170 | |||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
Experiment Methods: | Single-end sequencing. | |||||||||
Position: |
|
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
Database | Acc Id | Source(s) |
AGR Gene | RGD:1595491 | AgrOrtholog |
Ensembl Genes | ENSRNOG00000013583 | ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000018640 | ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000018640 | ENTREZGENE, UniProtKB/TrEMBL |
Gene3D-CATH | 2.30.29.30 | UniProtKB/TrEMBL |
InterPro | EF-hand-like_dom | UniProtKB/TrEMBL |
EF_hand_Ca-bd | UniProtKB/TrEMBL | |
GRAM | UniProtKB/TrEMBL | |
PH-like_dom_sf | UniProtKB/TrEMBL | |
Rab-GTPase_TBC_sf | UniProtKB/TrEMBL | |
RabGAP/TBC_dom | UniProtKB/TrEMBL | |
TBC1D8_PH-GRAM1 | UniProtKB/TrEMBL | |
TBC1D8_PH-GRAM2 | UniProtKB/TrEMBL | |
KEGG Report | rno:680133 | UniProtKB/TrEMBL |
NCBI Gene | 680133 | ENTREZGENE |
Pfam | GRAM | UniProtKB/TrEMBL |
TBC | UniProtKB/TrEMBL | |
PhenoGen | Tbc1d8 | PhenoGen |
PROSITE | EF_HAND_2 | UniProtKB/TrEMBL |
TBC_RABGAP | UniProtKB/TrEMBL | |
SMART | GRAM | UniProtKB/TrEMBL |
TBC | UniProtKB/TrEMBL | |
Superfamily-SCOP | RabGAP_TBC | UniProtKB/TrEMBL |
SSF47473 | UniProtKB/TrEMBL | |
UniGene | Rn.205305 | ENTREZGENE |
UniProt | F1LWZ7 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2013-05-24 | Tbc1d8 | TBC1 domain family, member 8 | LOC100364476 | rCG22278-like | Data Merged | 1643240 | APPROVED |
2010-05-05 | LOC100364476 | rCG22278-like | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2010-04-21 | Tbc1d8 | TBC1 domain family, member 8 | LOC680133 | similar to TBC1 domain family, member 8 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-01-09 | LOC680133 | similar to TBC1 domain family, member 8 | LOC681648 | similar to TBC1 domain family, member 8 | Data Merged | 1643240 | APPROVED |
2006-11-20 | LOC680133 | similar to TBC1 domain family, member 8 | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2006-11-20 | LOC681648 | similar to TBC1 domain family, member 8 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
![]() |
More on Tbc1d8 | |
![]() |
Alliance Gene |
![]() |
NCBI Gene |
![]() |
Ensembl Gene |
![]() |
JBrowse: rn5 rn6 |
![]() |
NCBI Genome Data Viewer |
RGD Object Information | |
RGD ID: | 1595491 |
Created: | 2006-11-20 |
Species: | Rattus norvegicus |
Last Modified: | 2019-11-27 |
Status: | ACTIVE |
![]() |
![]() |
![]() |
![]() |
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.