Gene: Zfp451 (zinc finger protein 451) Rattus norvegicus
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Symbol: Zfp451
Name: zinc finger protein 451
Description: ENCODES a protein that exhibits SUMO ligase activity (ortholog); transcription corepressor activity (ortholog); INVOLVED IN negative regulation of histone H3-K9 acetylation (ortholog); negative regulation of transcription initiation from RNA polymerase II promoter (ortholog); negative regulation of transforming growth factor beta receptor signaling pathway (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; chloroprene
AGR Description: Predicted to have SUMO ligase activity and transcription corepressor activity; predicted to be involved in negative regulation of cellular metabolic process, negative regulation of transforming growth factor beta receptor signaling pathway, and protein sumoylation; predicted to localize to the nucleus; orthologous to human ZNF451 (zinc finger protein 451).
Merged Description: Predicted to have SUMO ligase activity and transcription corepressor activity; predicted to be involved in negative regulation of cellular metabolic process, negative regulation of transforming growth factor beta receptor signaling pathway, and protein sumoylation; predicted to localize to the nucleus; orthologous to human ZNF451 (zinc finger protein 451); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; chloroprene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 SUMO-protein ligase ZNF451; LOC316312; MGC124741
Orthologs:
Homo sapiens (human) : ZNF451 (zinc finger protein 451)  HGNC  Alliance
Mus musculus (house mouse) : Zfp451 (zinc finger protein 451)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Znf451 (zinc finger protein 451)
Pan paniscus (bonobo/pygmy chimpanzee) : ZNF451 (zinc finger protein 451)
Canis lupus familiaris (dog) : ZNF451 (zinc finger protein 451)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Znf451 (zinc finger protein 451)
Sus scrofa (pig) : ZNF451 (zinc finger protein 451)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0938,395,464 - 38,451,585 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0938,077,865 - 38,133,122 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4932,506,481 - 32,561,688 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1932,493,198 - 32,563,138 (-)NCBI
Celera933,778,050 - 33,833,256 (-)NCBICelera
Cytogenetic Map9q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Zfp451
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305865
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.