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Gene: Cyp39a1 (cytochrome P450, family 39, subfamily a, polypeptide 1) Rattus norvegicus
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Symbol: Cyp39a1
Name: cytochrome P450, family 39, subfamily a, polypeptide 1
Description: Predicted to have oxysterol 7-alpha-hydroxylase activity and steroid 7-alpha-hydroxylase activity. Predicted to be involved in bile acid biosynthetic process; cholesterol catabolic process; and cholesterol homeostasis. Predicted to localize to endoplasmic reticulum membrane. Orthologous to human CYP39A1 (cytochrome P450 family 39 subfamily A member 1); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 24-hydroxycholesterol 7-alpha-hydroxylase; LOC301264
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0919,804,079 - 19,880,346 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,804,079 - 19,880,346 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,681,949 - 18,758,013 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4912,926,125 - 13,002,576 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1912,924,912 - 12,999,586 (-)NCBI
Celera914,954,224 - 15,030,308 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cyp39a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307471
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.