Gsta3 (glutathione S-transferase alpha 3) - Rat Genome Database

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Gene: Gsta3 (glutathione S-transferase alpha 3) Rattus norvegicus
Analyze
Symbol: Gsta3
Name: glutathione S-transferase alpha 3
RGD ID: 1591980
Description: Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process and xenobiotic metabolic process. Predicted to act upstream of or within aflatoxin catabolic process and ureteric bud development. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human GSTA5 (glutathione S-transferase alpha 5); PARTICIPATES IN glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dimethylhydrazine; 1-bromopropane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glutathione S-transferase A3; glutathione S-transferase alpha-5; glutathione S-transferase Yc-2; glutathione S-transferase Yc2 subunit; glutathione S-transferase, alpha 3; GST A5-5; GST Yc2; Gsta5; MGC112704; Yc2
RGD Orthologs
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2923,658,574 - 23,684,240 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl923,658,574 - 23,684,240 (+)Ensembl
Rnor_6.0927,357,490 - 27,417,023 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl927,402,381 - 27,417,023 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0926,210,389 - 26,264,080 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4920,005,570 - 20,032,031 (+)NCBIRGSC3.4rn4RGSC3.4
Celera921,234,385 - 21,259,542 (+)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-amphetamine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-bromopropane  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-Cyano-2-hydroxy-3-butene  (EXP)
1-naphthyl isothiocyanate  (EXP,ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
1H-imidazole  (EXP)
1H-pyrazole  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-acetamidofluorene  (ISO)
2-allylphenol  (EXP)
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxynon-2-enal  (EXP,ISO)
4-Propylphenol  (EXP)
6-propyl-2-thiouracil  (EXP)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
8,9-dihydro-8-(S-glutathionyl)-9-hydroxyaflatoxin B1  (ISO)
aconitine  (EXP)
aflatoxin B1  (EXP,ISO)
aflatoxin B1 exo-8,9-epoxide  (EXP,ISO)
allyl isothiocyanate  (ISO)
ammonium chloride  (EXP)
ampicillin  (EXP)
angelica lactone  (ISO)
antimycin A  (ISO)
aristolochic acid  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzene  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzotriazole  (EXP)
benzyl isothiocyanate  (EXP,ISO)
beta-naphthoflavone  (EXP,ISO)
bifenthrin  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bromosulfophthalein  (EXP)
buta-1,3-diene  (ISO)
butylated hydroxyanisole  (EXP,ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cafestol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
chlorambucil  (EXP)
chlordecone  (ISO)
chlorohydrocarbon  (EXP)
chloroprene  (ISO)
cholic acid  (EXP,ISO)
ciguatoxin CTX1B  (ISO)
ciprofibrate  (EXP)
cisplatin  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
corticosterone  (EXP)
coumarin  (EXP,ISO)
cumene hydroperoxide  (EXP,ISO)
Cuprizon  (EXP)
curcumin  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cyproconazole  (ISO)
Diallyl sulfide  (EXP)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
diethyl malate  (ISO)
diethyl maleate  (EXP,ISO)
diethyl phthalate  (EXP)
diethyldithiocarbamic acid  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
diquat  (EXP)
diuron  (EXP)
doramapimod  (ISO)
doxorubicin  (EXP)
ebselen  (EXP)
elemental selenium  (EXP,ISO)
epoxiconazole  (ISO)
Erucin  (ISO)
etacrynic acid  (ISO)
ethanol  (EXP,ISO)
ethoxyquin  (EXP,ISO)
eugenol  (EXP)
fenofibrate  (EXP)
Fenoprop  (EXP)
finasteride  (EXP)
fipronil  (ISO)
flutamide  (EXP,ISO)
folpet  (ISO)
fumonisin B1  (ISO)
furan  (EXP,ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glutathione  (EXP,ISO)
Glutathione ethyl ester  (ISO)
glycochenodeoxycholic acid  (EXP)
graphene oxide  (ISO)
GW 4064  (ISO)
herbicide  (EXP)
Hexachloro-1,3-butadiene  (EXP)
hexachlorobenzene  (EXP)
hydrazine  (EXP)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
iberin  (ISO)
indole-3-methanol  (EXP,ISO)
indometacin  (EXP)
iodide salt  (EXP)
irinotecan  (EXP)
isomethyleugenol  (EXP)
isothiocyanate  (ISO)
kojic acid  (EXP)
L-cysteine  (EXP,ISO)
L-methionine  (EXP)
L-selenocysteine  (EXP)
lead diacetate  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
lithocholic acid  (EXP)
maneb  (EXP)
mechlorethamine  (EXP)
melphalan  (EXP)
mercury atom  (ISO)
mercury dichloride  (ISO)
mercury(0)  (ISO)
metacetamol  (ISO)
methamphetamine  (EXP)
methyl isothiocyanate  (ISO)
methyl methacrylate  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (EXP,ISO)
metronidazole  (EXP)
microcystin  (EXP)
microcystin-LR  (ISO)
N-acetylsphingosine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-hydroxy-PhIP  (EXP)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nafenopin  (EXP)
naphthalene  (ISO)
nefazodone  (EXP)
neomycin  (EXP)
nickel dichloride  (ISO)
nimesulide  (EXP)
nitrofen  (EXP)
nitrogen mustard  (EXP)
nitroglycerin  (EXP)
O-methyleugenol  (EXP)
ochratoxin A  (EXP)
oltipraz  (EXP,ISO)
oxaliplatin  (EXP)
oxycodone  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PCB138  (EXP)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenethyl isothiocyanate  (EXP,ISO)
phenobarbital  (EXP,ISO)
PhIP  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
propiconazole  (ISO)
pyrogallol  (ISO)
quercetin  (EXP,ISO)
Reactive blue 2  (EXP)
resveratrol  (ISO)
riddelliine  (EXP)
rose bengal  (EXP)
rotenone  (EXP,ISO)
selenium atom  (EXP,ISO)
serpentine asbestos  (ISO)
sevoflurane  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
sodium fluoride  (ISO)
Soman  (EXP)
stilbene oxide  (EXP)
streptozocin  (EXP)
succimer  (ISO)
sulfasalazine  (ISO)
sulforaphane  (ISO)
tamoxifen  (EXP,ISO)
tert-butyl ethyl ether  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thiazoles  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
triadimefon  (ISO)
triazines  (ISO)
triazoles  (EXP)
trichloroethene  (ISO)
trimetrexate  (EXP)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
ursodeoxycholic acid  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vanadyl sulfate  (EXP)
vancomycin  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1953636   PMID:6325423   PMID:8051171   PMID:8144363   PMID:8761455   PMID:8889548   PMID:12477932   PMID:16545622   PMID:19850059   PMID:27602565   PMID:31443720   PMID:31617428  


Genomics

Comparative Map Data
Gsta3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2923,658,574 - 23,684,240 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl923,658,574 - 23,684,240 (+)Ensembl
Rnor_6.0927,357,490 - 27,417,023 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl927,402,381 - 27,417,023 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0926,210,389 - 26,264,080 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4920,005,570 - 20,032,031 (+)NCBIRGSC3.4rn4RGSC3.4
Celera921,234,385 - 21,259,542 (+)NCBICelera
Cytogenetic Map9q13NCBI
Gsta3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39121,310,789 - 21,335,799 (+)NCBIGRCm39mm39
GRCm39 Ensembl121,310,813 - 21,335,885 (+)Ensembl
GRCm38121,240,565 - 21,265,575 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl121,240,589 - 21,265,661 (+)EnsemblGRCm38mm10GRCm38
MGSCv37121,230,670 - 21,255,640 (+)NCBIGRCm37mm9NCBIm37
MGSCv36121,225,799 - 21,250,362 (+)NCBImm8
Celera121,109,818 - 21,134,784 (+)NCBICelera
Cytogenetic Map1A4NCBI
cM Map16.5NCBI

Position Markers
RH131621  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2923,711,413 - 23,711,630 (+)MAPPERmRatBN7.2
Rnor_6.0927,444,195 - 27,444,411NCBIRnor6.0
Rnor_6.0927,372,297 - 27,372,513NCBIRnor6.0
Rnor_5.0926,291,488 - 26,291,704UniSTSRnor5.0
Rnor_5.0926,222,128 - 26,222,344UniSTSRnor5.0
RGSC_v3.4920,059,439 - 20,059,655UniSTSRGSC3.4
Celera921,286,558 - 21,286,774UniSTS
RH 3.4 Map2052.92UniSTS
Cytogenetic Map9q13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:23
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000040950
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 37 37 31 2 1
Low 13 4 13 4 3 3 12 4 32 10 3
Below cutoff 9 7 6 5 6 38 6 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001009920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001159739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001287025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC100080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ201014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO566642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY308874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY573045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S72506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S82820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X78847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000077372   ⟹   ENSRNOP00000068639
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl927,402,381 - 27,416,409 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085195   ⟹   ENSRNOP00000069606
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl923,658,574 - 23,679,455 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088416   ⟹   ENSRNOP00000074697
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl923,658,574 - 23,684,240 (+)Ensembl
Rnor_6.0 Ensembl927,408,333 - 27,417,023 (+)Ensembl
RefSeq Acc Id: NM_001009920   ⟹   NP_001009920
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2923,670,631 - 23,684,240 (+)NCBI
Rnor_6.0927,402,153 - 27,417,023 (+)NCBI
Rnor_5.0926,210,389 - 26,264,080 (+)NCBI
RGSC_v3.4920,005,570 - 20,032,031 (+)RGD
Celera921,246,410 - 21,259,542 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001159739   ⟹   NP_001153211
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2923,658,574 - 23,684,240 (+)NCBI
Rnor_6.0927,357,490 - 27,417,023 (+)NCBI
Rnor_5.0926,210,389 - 26,264,080 (+)NCBI
RGSC_v3.4920,005,570 - 20,032,031 (+)RGD
Celera921,234,385 - 21,259,542 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001287025   ⟹   NP_001273954
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2923,658,574 - 23,684,240 (+)NCBI
Rnor_6.0927,357,490 - 27,417,023 (+)NCBI
Celera921,234,385 - 21,259,542 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039084047   ⟹   XP_038939975
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2923,666,103 - 23,684,037 (+)NCBI
RefSeq Acc Id: XM_039084048   ⟹   XP_038939976
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2923,658,724 - 23,679,457 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001009920   ⟸   NM_001009920
- Peptide Label: isoform 1
- UniProtKB: P46418 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001153211   ⟸   NM_001159739
- Peptide Label: isoform 1
- UniProtKB: P46418 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001273954   ⟸   NM_001287025
- Peptide Label: isoform 2
- UniProtKB: A0A0G2K8Q5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068639   ⟸   ENSRNOT00000077372
RefSeq Acc Id: ENSRNOP00000074697   ⟸   ENSRNOT00000088416
RefSeq Acc Id: XP_038939976   ⟸   XM_039084048
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038939975   ⟸   XM_039084047
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000069606   ⟸   ENSRNOT00000085195
Protein Domains
GST C-terminal   GST N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JTB1-F1-model_v2 AlphaFold A0A0G2JTB1 1-220 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696577
Promoter ID:EPDNEW_R7101
Type:single initiation site
Name:Gsta3_1
Description:glutathione S-transferase alpha 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0927,402,284 - 27,402,344EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
9 20018420 20018421 G T snv SS/JrHsdMcwi (MCW)


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-28008 BioCyc
Ensembl Genes ENSRNOG00000013484 UniProtKB/TrEMBL
  ENSRNOG00000056847 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000068639 UniProtKB/TrEMBL
  ENSRNOP00000069606 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000074697 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077372 UniProtKB/TrEMBL
  ENSRNOT00000085195 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000088416 ENTREZGENE, UniProtKB/TrEMBL
InterPro Glutathione-S-Trfase_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione_S-Trfase UniProtKB/TrEMBL
  Glutathione_S-Trfase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:494500 UniProtKB/Swiss-Prot
NCBI Gene 494500 ENTREZGENE
Pfam GST_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gsta3 PhenoGen
PRINTS GSTRNSFRASEA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GST_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_NTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47616 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JTB1_RAT UniProtKB/TrEMBL
  A0A0G2JVT2_RAT UniProtKB/TrEMBL
  A0A0G2K8Q5 ENTREZGENE, UniProtKB/TrEMBL
  GSTA5_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q498T5_RAT UniProtKB/TrEMBL
  Q9JLQ6_RAT UniProtKB/TrEMBL
UniProt Secondary Q6LD91 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-02-04 Gsta3  glutathione S-transferase alpha 3  Gsta3  glutathione S-transferase A3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-03 Gsta3  glutathione S-transferase A3  Gsta3  glutathione S-transferase, alpha 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Gsta3  glutathione S-transferase, alpha 3  Yc2  glutathione S-transferase Yc2 subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 Yc2  glutathione S-transferase Yc2 subunit      Symbol and Name status set to provisional 70820 PROVISIONAL