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Gene: Vegfa (vascular endothelial growth factor A) Rattus norvegicus
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Symbol: Vegfa
Name: vascular endothelial growth factor A
Description: Exhibits several functions, including protein homodimerization activity; receptor ligand activity; and vascular endothelial growth factor receptor 2 binding activity. Involved in several processes, including negative regulation of cell death; response to steroid hormone; and response to vitamin. Localizes to the basement membrane; extracellular space; and vesicle. Used to study brain edema; glaucoma; limb ischemia; proliferative diabetic retinopathy; and pulmonary edema. Biomarker of several diseases, including attention deficit hyperactivity disorder; brain edema; congenital diaphragmatic hernia; decubitus ulcer; and retinal vascular disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; hematologic cancer (multiple); hypertension (multiple); reproductive organ cancer (multiple); and retinal disease (multiple). Orthologous to human VEGFA (vascular endothelial growth factor A); PARTICIPATES IN vascular endothelial growth factor signaling pathway; altered vascular endothelial growth factor signaling pathway involving proteins affecting its expression; altered vascular endothelial growth factor signaling pathway involving the main players; INTERACTS WITH (+)-pilocarpine; (R)-lipoic acid; (RS)-amphetamine.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: vascular endothelial growth factor; vascular permeability factor; Vegf; VEGF-A; VEGF111; VEGF164; VPF
Orthologs:
Homo sapiens (human) : VEGFA (vascular endothelial growth factor A)  HGNC  Alliance
Mus musculus (house mouse) : Vegfa (vascular endothelial growth factor A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vegfa (vascular endothelial growth factor A)
Pan paniscus (bonobo/pygmy chimpanzee) : VEGFA (vascular endothelial growth factor A)
Canis lupus familiaris (dog) : VEGFA (vascular endothelial growth factor A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vegfa (vascular endothelial growth factor A)
Sus scrofa (pig) : VEGFA (vascular endothelial growth factor A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0917,340,341 - 17,355,681 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0916,232,415 - 16,247,658 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4910,520,730 - 10,536,071 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1910,519,065 - 10,531,506 (+)NCBI
Celera912,701,425 - 12,716,765 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model