Vegfa (vascular endothelial growth factor A) - Rat Genome Database

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Gene: Vegfa (vascular endothelial growth factor A) Rattus norvegicus
Symbol: Vegfa
Name: vascular endothelial growth factor A
RGD ID: 619991
Description: Enables several functions, including identical protein binding activity; receptor ligand activity; and vascular endothelial growth factor receptor 2 binding activity. Involved in several processes, including positive regulation of macromolecule biosynthetic process; response to steroid hormone; and response to vitamin. Located in basement membrane; extracellular space; and vesicle. Used to study several diseases, including brain edema; limb ischemia; middle cerebral artery infarction; ovarian hyperstimulation syndrome; and proliferative diabetic retinopathy. Biomarker of several diseases, including adhesions of uterus; attention deficit hyperactivity disorder; brain edema; liver disease (multiple); and retinal vascular disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); hypertension (multiple); and reproductive organ cancer (multiple). Orthologous to human VEGFA (vascular endothelial growth factor A); PARTICIPATES IN phosphatidylinositol 3-kinase-Akt signaling pathway; vascular endothelial growth factor signaling pathway; altered vascular endothelial growth factor signaling pathway involving proteins affecting its expression; INTERACTS WITH (+)-pilocarpine; (R)-lipoic acid; (S)-nicotine.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: vascular endothelial growth factor; vascular permeability factor; Vegf; VEGF-A; VEGF111; VEGF164; VPF
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2914,955,300 - 14,970,641 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,955,300 - 14,970,641 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx923,540,015 - 23,555,341 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0928,602,643 - 28,617,969 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,903,445 - 26,918,771 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,340,341 - 17,355,681 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,340,341 - 17,355,681 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,232,415 - 16,247,658 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4910,520,730 - 10,536,071 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1910,519,065 - 10,531,506 (+)NCBI
Celera912,701,425 - 12,716,765 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)