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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:17833
Term: gentamycin
Definition: Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.
Chemical ID: MESH:D005839
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfadecreases expressionEXP 6480464CTDGentamicins results in decreased expression of VEGFA proteinPMID:25051504
Vegfaincreases expressionEXP 6480464CTDGentamicins results in increased expression of VEGFA mRNA; Gentamicins results in increased expression of VEGFA proteinPMID:14986132 PMID:33387578
Vegfaincreases secretionEXP 6480464CTDGentamicins results in increased secretion of VEGFA proteinPMID:20816719
Vegfamultiple interactionsEXP 6480464CTD[Gentamicins co-treated with cobaltous chloride] results in increased expression of VEGFA mRNAPMID:23145036
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