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Gene: VEGFA (vascular endothelial growth factor A) Homo sapiens
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Symbol: VEGFA
Name: vascular endothelial growth factor A
Description: Exhibits several functions, including fibronectin binding activity; heparin binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of macromolecule metabolic process; regulation of signal transduction; and vascular endothelial growth factor signaling pathway. Localizes to several cellular components, including the cell surface; cell-cell adherens junction; and secretory granule. Implicated in several diseases, including Graves' disease; hematologic cancer (multiple); hypertension (multiple); reproductive organ cancer (multiple); and retinal disease (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); cholesteatoma (multiple); eye disease (multiple); and inflammatory bowel disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC70609; MVCD1; vascular endothelial growth factor; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular permeability factor; VEGF; VEGF-A; VPF
Orthologs:
Mus musculus (house mouse) : Vegfa (vascular endothelial growth factor A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Vegfa (vascular endothelial growth factor A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vegfa (vascular endothelial growth factor A)
Pan paniscus (bonobo/pygmy chimpanzee) : VEGFA (vascular endothelial growth factor A)
Canis lupus familiaris (dog) : VEGFA (vascular endothelial growth factor A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vegfa (vascular endothelial growth factor A)
Sus scrofa (pig) : VEGFA (vascular endothelial growth factor A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38643,770,209 - 43,786,487 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37643,737,946 - 43,754,224 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,845,931 - 43,862,202 (+)NCBINCBI36hg18NCBI36
Build 34643,845,923 - 43,860,314NCBI
Celera645,289,570 - 45,305,849 (+)NCBI
Cytogenetic Map6p21.1NCBI
HuRef643,458,106 - 43,474,385 (+)NCBIHuRef
CHM1_1643,741,412 - 43,757,691 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations