VEGFA (vascular endothelial growth factor A) - Rat Genome Database

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Gene: VEGFA (vascular endothelial growth factor A) Homo sapiens
Symbol: VEGFA
Name: vascular endothelial growth factor A
RGD ID: 731072
HGNC Page HGNC:12680
Description: Enables several functions, including fibronectin binding activity; heparin binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of cell migration; positive regulation of intracellular signal transduction; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including branching involved in blood vessel morphogenesis; positive regulation of endothelial cell proliferation; and regulation of nitric oxide mediated signal transduction. Located in several cellular components, including VEGF-A complex; adherens junction; and secretory granule. Implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); hypertension (multiple); and reproductive organ cancer (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); inflammatory bowel disease (multiple); and respiratory system cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: MGC70609; MVCD1; vascular endothelial growth factor; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular permeability factor; VEGF; VEGF-A; VPF
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in cytokine storm inflammatory response.
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38643,770,209 - 43,786,487 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl643,770,184 - 43,786,487 (+)EnsemblGRCh38hg38GRCh38
GRCh37643,737,946 - 43,754,224 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,845,931 - 43,862,202 (+)NCBINCBI36Build 36hg18NCBI36
Build 34643,845,923 - 43,860,314NCBI
Celera645,289,570 - 45,305,849 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef643,458,106 - 43,474,385 (+)NCBIHuRef
CHM1_1643,741,412 - 43,757,691 (+)NCBICHM1_1
T2T-CHM13v2.0643,599,722 - 43,616,002 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)