VEGFA (vascular endothelial growth factor A) - Rat Genome Database

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Gene: VEGFA (vascular endothelial growth factor A) Pan paniscus
Analyze
Symbol: VEGFA
Name: vascular endothelial growth factor A
RGD ID: 11745640
Description: ENCODES a protein that exhibits chemoattractant activity (ortholog); growth factor activity (ortholog); growth factor binding (ortholog); INVOLVED IN angiogenesis (ortholog); angiogenesis involved in coronary vascular morphogenesis (ortholog); apoptotic process (ortholog); PARTICIPATES IN altered vascular endothelial growth factor signaling pathway involving proteins affecting its expression; altered vascular endothelial growth factor signaling pathway involving the main players; bevacizumab pharmacodynamics pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acute chest syndrome (ortholog); acute kidney failure (ortholog); FOUND IN basement membrane (ortholog); extracellular space (ortholog); VEGF-A complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100970217; vascular endothelial growth factor A, long form
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,269,186 - 58,285,503 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,138,950 - 54,155,259 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,361,053 - 43,377,366 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1644,651,855 - 44,666,353 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl644,650,365 - 44,666,353 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acoustic neuroma  (ISO)
acute chest syndrome  (ISO)
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
adhesions of uterus  (ISO)
adult-onset Still's disease  (ISO)
Alcoholic Liver Diseases  (ISO)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (ISO)
amyotrophic lateral sclerosis type 1  (ISO)
angiosarcoma  (ISO)
Arteriovenous Fistula  (ISO)
arteriovenous malformations of the brain  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atrial fibrillation  (ISO)
attention deficit hyperactivity disorder  (ISO)
autoimmune hepatitis  (ISO)
Behcet's disease  (ISO)
blindness  (ISO)
brain edema  (ISO)
brain glioma  (ISO)
Brain Hypoxia-Ischemia  (ISO)
Brain Injuries  (ISO)
Brain Neoplasms  (ISO)
Breast Neoplasms  (ISO)
bullous pemphigoid  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
Cerebral Hemorrhage  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
cholangiocarcinoma  (ISO)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Bronchitis  (ISO)
chronic fatigue syndrome  (ISO)
Chronic Intermittent Hypoxia  (ISO)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
clear cell renal cell carcinoma  (ISO)
colon cancer  (ISO)
colon carcinoma  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
congenital diaphragmatic hernia  (ISO)
congenital heart disease  (ISO)
congestive heart failure  (ISO)
contact dermatitis  (ISO)
corneal neovascularization  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
decubitus ulcer  (ISO)
dermatitis herpetiformis  (ISO)
Diabetes Complications  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
DiGeorge syndrome  (ISO)
disease of cellular proliferation  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
ductal carcinoma in situ  (ISO)
duodenal ulcer  (ISO)
Endometrial Neoplasms  (ISO)
endometriosis  (ISO)
erythema multiforme  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Neoplasms  (ISO)
extrinsic allergic alveolitis  (ISO)
gastric ulcer  (ISO)
genetic disease  (ISO)
gingivitis  (ISO)
glaucoma  (ISO)
glioblastoma  (ISO)
gliosarcoma  (ISO)
glomerulonephritis  (ISO)
Glomus Tympanicum Tumor  (ISO)
graft-versus-host disease  (ISO)
granulosa cell tumor  (ISO)
Graves' disease  (ISO)
Head and Neck Neoplasms  (ISO)
heart disease  (ISO)
Hemorrhage  (ISO)
hepatocellular carcinoma  (ISO)
hepatopulmonary syndrome  (ISO)
Hypercholesterolemia  (ISO)
Hyperplasia  (ISO)
hypertension  (ISO)
impotence  (ISO)
Infantile Capillary Hemangioma  (ISO)
infantile Refsum disease  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
intracranial aneurysm  (ISO)
Invasive Pulmonary Aspergillosis  (ISO)
inverted papilloma  (ISO)
ischemic colitis  (ISO)
Kawasaki disease  (ISO)
Kuhnt-Junius degeneration  (ISO)
larynx cancer  (ISO)
learning disability  (ISO)
limb ischemia  (ISO)
liver cirrhosis  (ISO)
Liver Failure  (ISO)
Liver Metastasis  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (ISO)
lung non-small cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
macular degeneration  (ISO)
macular retinal edema  (ISO)
melanoma  (ISO)
Memory Disorders  (ISO)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
multiple myeloma  (ISO)
myeloid leukemia  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
nasopharynx carcinoma  (ISO)
Neoplasm Metastasis  (ISO)
Neoplasm Recurrence, Local  (ISO)
Neoplastic Cell Transformation  (ISO)
neovascular glaucoma  (ISO)
Neovascularization, Pathologic  (ISO)
Nerve Degeneration  (ISO)
neurofibromatosis 1  (ISO)
neurofibrosarcoma  (ISO)
newborn respiratory distress syndrome  (ISO)
opiate dependence  (ISO)
oral squamous cell carcinoma  (ISO)
osteochondrodysplasia  (ISO)
osteosarcoma  (ISO)
otitis media  (ISO)
Otitis Media with Effusion  (ISO)
ovarian hyperstimulation syndrome  (ISO)
Ovarian Neoplasms  (ISO)
Oxygen-Induced Retinopathy  (ISO)
pancreatic ductal carcinoma  (ISO)
Periodontal Atrophy  (ISO)
polyarteritis nodosa  (ISO)
polycystic ovary syndrome  (ISO)
Polypoidal Choroidal Vasculopathy  (ISO)
portal hypertension  (ISO)
pre-eclampsia  (ISO)
pre-malignant neoplasm  (ISO)
Pregnancy in Diabetics  (ISO)
primary biliary cholangitis  (ISO)
primary sclerosing cholangitis  (ISO)
proliferative diabetic retinopathy  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
proteinuria  (ISO)
pseudoxanthoma elasticum  (ISO)
psoriasis  (ISO)
pterygium  (ISO)
pulmonary edema  (ISO)
pulmonary hypertension  (ISO)
renal cell carcinoma  (ISO)
renal Wilms' tumor  (ISO)
respiratory allergy  (ISO)
Retina Reperfusion Injury  (ISO)
retinal disease  (ISO)
retinal ischemia  (ISO)
Retinal Neovascularization  (ISO)
retinal telangiectasia  (ISO)
retinal vein occlusion  (ISO)
retinitis pigmentosa  (ISO)
retinopathy of prematurity  (ISO)
rhabdomyosarcoma  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (ISO)
Right Ventricular Hypertrophy  (ISO)
Seasonal Allergic Rhinitis  (ISO)
seminoma  (ISO)
Skin Neoplasms  (ISO)
Small-For-Size Syndrome  (ISO)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
status epilepticus  (ISO)
Stroke  (ISO)
sudden infant death syndrome  (ISO)
systemic scleroderma  (ISO)
temporal lobe epilepsy  (ISO)
Thrombotic Microangiopathies  (ISO)
Tongue Neoplasms  (ISO)
Tympanic Membrane Perforation  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
Urologic Neoplasms  (ISO)
Uterine Cervical Neoplasms  (ISO)
uveal melanoma  (ISO)
Ventricular Remodeling  (ISO)
vestibular schwannomatosis  (ISO)
Wounds and Injuries  (ISO)
Zellweger syndrome  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IEA,ISO)
angiogenesis involved in coronary vascular morphogenesis  (ISO)
apoptotic process  (IEA,ISO)
artery morphogenesis  (IEA,ISO)
basophil chemotaxis  (ISO)
blood vessel development  (IEA,ISO)
blood vessel morphogenesis  (IEA,ISO)
blood vessel remodeling  (ISO)
bone trabecula formation  (IEA,ISO)
bone trabecula morphogenesis  (IEA,ISO)
branching involved in blood vessel morphogenesis  (IEA,ISO)
camera-type eye morphogenesis  (IEA,ISO)
cardiac muscle cell development  (IEA,ISO)
cardiac vascular smooth muscle cell development  (ISO)
cell chemotaxis  (ISO)
cell differentiation  (IEA)
cell migration  (IEA,ISO)
cell migration involved in sprouting angiogenesis  (IEA)
cell population proliferation  (IEA,ISO)
cell-cell adhesion  (IEA,ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to estrogen stimulus  (ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to hypoxia  (IEA,ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to vascular endothelial growth factor stimulus  (IEA)
cellular response to wortmannin  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cellular stress response to acid chemical  (IEA)
commissural neuron axon guidance  (IEA,ISO)
coronary artery morphogenesis  (ISO)
coronary vein morphogenesis  (ISO)
dopaminergic neuron differentiation  (IEA,ISO)
endothelial cell chemotaxis  (IEA)
endothelial cell migration  (IEA,ISO)
endothelial cell proliferation  (IEA,ISO)
epithelial cell differentiation  (IEA,ISO)
epithelial cell maturation  (IEA,ISO)
epithelial cell proliferation  (IEA,ISO)
eye photoreceptor cell development  (IEA,ISO)
female pregnancy  (ISO)
heart morphogenesis  (IEA,ISO)
homeostasis of number of cells within a tissue  (IEA,ISO)
in utero embryonic development  (IEA,ISO)
induction of positive chemotaxis  (IEA)
kidney development  (IEA,ISO)
lactation  (IEA,ISO)
lung alveolus development  (ISO)
lung development  (IEA,ISO)
lung vasculature development  (IEA,ISO)
lymph vessel morphogenesis  (ISO)
lymphangiogenesis  (IEA,ISO)
macrophage differentiation  (IEA)
mammary gland alveolus development  (IEA,ISO)
mesoderm development  (IEA,ISO)
monocyte differentiation  (IEA)
motor neuron migration  (IEA)
mRNA stabilization  (ISO)
negative regulation of adherens junction organization  (IEA)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of blood-brain barrier permeability  (IEA)
negative regulation of bone resorption  (ISO)
negative regulation of cell-cell adhesion  (IEA,ISO)
negative regulation of cell-cell adhesion mediated by cadherin  (IEA)
negative regulation of epithelial to mesenchymal transition  (IEA)
negative regulation of establishment of endothelial barrier  (IEA)
negative regulation of extrinsic apoptotic signaling pathway  (ISO)
negative regulation of fat cell differentiation  (IEA,ISO)
negative regulation of gene expression  (IEA,ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of programmed cell death  (ISO)
negative regulation of transcription by RNA polymerase II  (IEA)
nervous system development  (ISO)
neuroblast proliferation  (IEA,ISO)
neuron apoptotic process  (ISO)
neuron development  (ISO)
outflow tract morphogenesis  (ISO)
ovarian follicle development  (IEA,ISO)
positive chemotaxis  (IEA)
positive regulation of angiogenesis  (IEA,ISO)
positive regulation of axon extension involved in axon guidance  (IEA,ISO)
positive regulation of blood vessel endothelial cell migration  (IEA)
positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis  (IEA,ISO)
positive regulation of branching involved in ureteric bud morphogenesis  (IEA)
positive regulation of cell adhesion  (IEA)
positive regulation of cell division  (IEA)
positive regulation of cell migration  (IEA)
positive regulation of cell migration involved in sprouting angiogenesis  (IEA)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway  (IEA)
positive regulation of cold-induced thermogenesis  (IEA)
positive regulation of DNA biosynthetic process  (ISO)
positive regulation of endothelial cell chemotaxis  (IEA)
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway  (IEA)
positive regulation of endothelial cell migration  (IEA)
positive regulation of endothelial cell proliferation  (IEA,ISO)
positive regulation of epithelial cell proliferation  (IEA,ISO)
positive regulation of epithelial tube formation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of focal adhesion assembly  (IEA)
positive regulation of gene expression  (IEA)
positive regulation of lymphangiogenesis  (IEA,ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of mast cell chemotaxis  (IEA)
positive regulation of neuroblast proliferation  (IEA,ISO)
positive regulation of osteoblast differentiation  (IEA,ISO)
positive regulation of p38MAPK cascade  (IEA)
positive regulation of peptidyl-serine phosphorylation  (IEA)
positive regulation of peptidyl-tyrosine autophosphorylation  (IEA)
positive regulation of peptidyl-tyrosine phosphorylation  (IEA,ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of positive chemotaxis  (IEA)
positive regulation of protein autophosphorylation  (ISO)
positive regulation of protein kinase C signaling  (IEA)
positive regulation of protein localization to early endosome  (ISO)
positive regulation of protein phosphorylation  (IEA)
positive regulation of protein-containing complex assembly  (IEA)
positive regulation of receptor internalization  (IEA)
positive regulation of receptor signaling pathway via STAT  (ISO)
positive regulation of signal transduction  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of sprouting angiogenesis  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of trophoblast cell migration  (IEA)
positive regulation of vascular endothelial growth factor signaling pathway  (IEA)
positive regulation of vascular permeability  (IEA,ISO)
post-embryonic camera-type eye development  (IEA,ISO)
primitive erythrocyte differentiation  (IEA,ISO)
regulation of cell shape  (IEA)
regulation of endothelial cell differentiation  (IEA,ISO)
regulation of growth  (IEA,ISO)
regulation of hematopoietic progenitor cell differentiation  (IEA,ISO)
regulation of nitric oxide mediated signal transduction  (IEA,ISO)
regulation of transcription by RNA polymerase II  (ISO)
response to dexamethasone  (ISO)
response to estradiol  (ISO)
response to folic acid  (ISO)
response to hypoxia  (IEA,ISO)
response to oxygen levels  (ISO)
response to progesterone  (ISO)
response to vitamin A  (ISO)
retinal ganglion cell axon guidance  (IEA,ISO)
signal transduction  (IEA)
sprouting angiogenesis  (IEA)
surfactant homeostasis  (IEA,ISO)
T-helper 1 type immune response  (ISO)
tissue remodeling  (ISO)
tube formation  (IEA)
vascular endothelial growth factor receptor signaling pathway  (IEA,ISO)
vascular endothelial growth factor receptor-2 signaling pathway  (IEA)
vascular endothelial growth factor signaling pathway  (IEA)
vascular wound healing  (IEA)
vasculature development  (IEA,ISO)
vasodilation  (IEA,ISO)
VEGF-activated neuropilin signaling pathway  (ISO)

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
VEGFA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,269,186 - 58,285,503 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,138,950 - 54,155,259 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,361,053 - 43,377,366 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1644,651,855 - 44,666,353 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl644,650,365 - 44,666,353 (+)Ensemblpanpan1.1panPan2
VEGFA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38643,770,211 - 43,786,487 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl643,770,184 - 43,786,487 (+)EnsemblGRCh38hg38GRCh38
GRCh37643,737,946 - 43,754,224 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,845,931 - 43,862,202 (+)NCBINCBI36Build 36hg18NCBI36
Build 34643,845,923 - 43,860,314NCBI
Celera645,289,570 - 45,305,849 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef643,458,106 - 43,474,385 (+)NCBIHuRef
CHM1_1643,741,412 - 43,757,691 (+)NCBICHM1_1
T2T-CHM13v2.0643,599,724 - 43,616,002 (+)NCBIT2T-CHM13v2.0
Vegfa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391746,327,919 - 46,343,303 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1746,327,919 - 46,343,295 (-)EnsemblGRCm39 Ensembl
GRCm381746,016,993 - 46,032,377 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,016,993 - 46,032,369 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,153,942 - 46,169,326 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,480,574 - 45,495,331 (-)NCBIMGSCv36mm8
Celera1749,448,065 - 49,463,499 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.79NCBI
Vegfa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8922,452,854 - 22,468,194 (+)NCBIGRCr8
mRatBN7.2914,955,300 - 14,970,641 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,955,300 - 14,970,641 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx923,540,015 - 23,555,341 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0928,602,643 - 28,617,969 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,903,445 - 26,918,771 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,340,341 - 17,355,681 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,340,341 - 17,355,681 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,232,415 - 16,247,658 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4910,520,730 - 10,536,071 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1910,519,065 - 10,531,506 (+)NCBI
Celera912,701,425 - 12,716,765 (+)NCBICelera
Cytogenetic Map9q12NCBI
Vegfa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554379,527,445 - 9,541,908 (+)NCBIChiLan1.0ChiLan1.0
VEGFA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,209,032 - 12,224,978 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,208,231 - 12,224,965 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,235,225 - 12,250,737 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01212,693,104 - 12,708,614 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1212,691,593 - 12,708,601 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,217,730 - 12,233,243 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,305,204 - 12,320,707 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,398,451 - 12,413,981 (+)NCBIUU_Cfam_GSD_1.0
Vegfa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,698,881 - 47,715,068 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,247,100 - 16,260,673 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,245,134 - 16,261,180 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VEGFA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,746,052 - 38,761,366 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,746,393 - 38,762,282 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2744,459,821 - 44,475,711 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VEGFA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11728,377,959 - 28,394,508 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604443,823,884 - 43,842,951 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vegfa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475415,929,414 - 15,943,637 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000030367   ⟹   ENSPPAP00000007765
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl644,650,365 - 44,664,434 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000030369   ⟹   ENSPPAP00000007767
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl644,650,365 - 44,662,035 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000030385   ⟹   ENSPPAP00000007779
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl644,651,855 - 44,666,353 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000030387   ⟹   ENSPPAP00000007781
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl644,654,211 - 44,664,500 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000030390   ⟹   ENSPPAP00000007784
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl644,654,211 - 44,664,434 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000030391   ⟹   ENSPPAP00000007785
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl644,654,211 - 44,664,434 (+)Ensembl
RefSeq Acc Id: XM_034962167   ⟹   XP_034818058
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2558,270,968 - 58,285,503 (+)NCBI
NHGRI_mPanPan1654,140,737 - 54,155,259 (+)NCBI
Mhudiblu_PPA_v0643,362,862 - 43,377,366 (+)NCBI
RefSeq Acc Id: XM_034962168   ⟹   XP_034818059
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2558,270,352 - 58,285,503 (+)NCBI
NHGRI_mPanPan1654,140,116 - 54,155,259 (+)NCBI
Mhudiblu_PPA_v0643,362,216 - 43,377,366 (+)NCBI
RefSeq Acc Id: XM_034962170   ⟹   XP_034818061
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2558,269,187 - 58,285,503 (+)NCBI
NHGRI_mPanPan1654,138,951 - 54,155,259 (+)NCBI
Mhudiblu_PPA_v0643,361,054 - 43,377,366 (+)NCBI
RefSeq Acc Id: XM_057302507   ⟹   XP_057158490
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2558,269,187 - 58,285,503 (+)NCBI
NHGRI_mPanPan1654,138,950 - 54,155,259 (+)NCBI
RefSeq Acc Id: XM_057302508   ⟹   XP_057158491
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2558,269,191 - 58,285,503 (+)NCBI
NHGRI_mPanPan1654,138,954 - 54,155,259 (+)NCBI
RefSeq Acc Id: XM_063605286   ⟹   XP_063461356
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2558,269,186 - 58,285,503 (+)NCBI
RefSeq Acc Id: XM_063605287   ⟹   XP_063461357
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2558,271,817 - 58,285,503 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034818061   ⟸   XM_034962170
- Peptide Label: isoform X5
- UniProtKB: A0A2R8ZTA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034818059   ⟸   XM_034962168
- Peptide Label: isoform X4
- UniProtKB: A0A2R8ZXX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034818058   ⟸   XM_034962167
- Peptide Label: isoform X4
- UniProtKB: A0A2R8ZXX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000007784   ⟸   ENSPPAT00000030390
RefSeq Acc Id: ENSPPAP00000007785   ⟸   ENSPPAT00000030391
RefSeq Acc Id: ENSPPAP00000007781   ⟸   ENSPPAT00000030387
RefSeq Acc Id: ENSPPAP00000007779   ⟸   ENSPPAT00000030385
RefSeq Acc Id: ENSPPAP00000007765   ⟸   ENSPPAT00000030367
RefSeq Acc Id: ENSPPAP00000007767   ⟸   ENSPPAT00000030369
RefSeq Acc Id: XP_057158490   ⟸   XM_057302507
- Peptide Label: isoform X1
RefSeq Acc Id: XP_057158491   ⟸   XM_057302508
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZXX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063461356   ⟸   XM_063605286
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063461357   ⟸   XM_063605287
- Peptide Label: isoform X4
Protein Domains
Platelet-derived growth factor (PDGF) family


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027018 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000030367.1 UniProtKB/TrEMBL
  ENSPPAT00000030369.1 UniProtKB/TrEMBL
  ENSPPAT00000030385.1 UniProtKB/TrEMBL
  ENSPPAT00000030387.1 UniProtKB/TrEMBL
  ENSPPAT00000030390.1 UniProtKB/TrEMBL
  ENSPPAT00000030391.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.160.10 UniProtKB/TrEMBL
  2.10.90.10 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  PD_growth_factor_CS UniProtKB/TrEMBL
  PDGF/VEGF_dom UniProtKB/TrEMBL
  VEGF_C UniProtKB/TrEMBL
  VEGF_C_sf UniProtKB/TrEMBL
KEGG Report pps:100970217 UniProtKB/TrEMBL
NCBI Gene LOC100970217 ENTREZGENE
PANTHER VASCULAR ENDOTHELIAL GROWTH FACTOR UniProtKB/TrEMBL
  VASCULAR ENDOTHELIAL GROWTH FACTOR A UniProtKB/TrEMBL
Pfam PDGF UniProtKB/TrEMBL
  VEGF_C UniProtKB/TrEMBL
PROSITE PDGF_1 UniProtKB/TrEMBL
  PDGF_2 UniProtKB/TrEMBL
SMART PDGF UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
  SSF57593 UniProtKB/TrEMBL
UniProt A0A2R8ZS31_PANPA UniProtKB/TrEMBL
  A0A2R8ZTA0_PANPA UniProtKB/TrEMBL
  A0A2R8ZTA5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZV79_PANPA UniProtKB/TrEMBL
  A0A2R8ZVA1_PANPA UniProtKB/TrEMBL
  A0A2R8ZXX3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-08 VEGFA  vascular endothelial growth factor A  LOC100970217    Symbol and/or name change 5135510 APPROVED