GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | increases expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | 27-hydroxycholesterol results in increased expression of VEGFA mRNA | PMID:27856279 | Vegfa | increases secretion | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | 27-hydroxycholesterol results in increased secretion of VEGFA protein | PMID:27856279 | Vegfa | multiple interactions | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein]; STAT3 protein promotes the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; STAT3 protein promotes the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein] | PMID:27856279 | |
Go Back to source page | Continue to Ontology report |