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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:36062
Term: 3,4-dihydroxybenzoic acid
Definition: A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.
Chemical ID: MESH:C009091
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfaincreases expressionEXP 6480464CTDprotocatechuic acid results in increased expression of VEGFA proteinPMID:16227210 PMID:31850806 PMID:32461003
Vegfamultiple interactionsEXP 6480464CTDprotocatechuic acid inhibits the reaction [methylmercuric chloride results in decreased expression of VEGFA protein]; protocatechuic acid inhibits the reaction [Methylmercury Compounds results in decreased expression of VEGFA protein]PMID:31850806 PMID:32461003
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