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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:82256
Term: ANTU
Definition: A naphthalene that has formula C11H10N2S.
Chemical ID: MESH:C005277
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfaincreases expressionEXP 6480464CTDalpha-naphthyl thiourea results in increased expression of VEGFA mRNA; alpha-naphthyl thiourea results in increased expression of VEGFA proteinPMID:30974023
Vegfamultiple interactionsEXP 6480464CTDchrysin inhibits the reaction [alpha-naphthyl thiourea results in increased expression of VEGFA mRNA]; Sildenafil Citrate inhibits the reaction [alpha-naphthyl thiourea results in increased expression of VEGFA mRNA]; Sildenafil Citrate inhibits the reaction [alpha-naphthyl thiourea results in increased expression of VEGFA protein]PMID:30974023
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