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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:34445
Term: 4-tert-Octylphenol
Definition: An alkylbenzene that has formula C14H22O.
Chemical ID: MESH:C105260
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfaincreases secretionISOVEGFA (Homo sapiens)6480464CTD4-tert-octylphenol results in increased secretion of VEGFA proteinPMID:18252963
Vegfamultiple interactionsISOVEGFA (Homo sapiens)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; fulvestrant inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; wortmannin inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]PMID:18252963
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