VEGFA (vascular endothelial growth factor A) - Rat Genome Database

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Gene: VEGFA (vascular endothelial growth factor A) Sus scrofa
Analyze
Symbol: VEGFA
Name: vascular endothelial growth factor A
RGD ID: 14230826
Description: ENCODES a protein that exhibits chemoattractant activity (ortholog); cytokine activity (ortholog); extracellular matrix binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); aging (ortholog); angiogenesis (ortholog); PARTICIPATES IN altered vascular endothelial growth factor signaling pathway involving proteins affecting its expression; altered vascular endothelial growth factor signaling pathway involving the main players; bevacizumab pharmacodynamics pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acute chest syndrome (ortholog); acute kidney failure (ortholog); FOUND IN adherens junction (ortholog); basement membrane (ortholog); cell surface (ortholog); INTERACTS WITH 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione; bisphenol A; gefitinib
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: vascular permeability factor; VEGF; VEGF-A; VPF
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,746,052 - 38,761,366 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,746,393 - 38,762,282 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2744,459,821 - 44,475,711 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acoustic neuroma  (ISO)
acute chest syndrome  (ISO)
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
adhesions of uterus  (ISO)
adult-onset Still's disease  (ISO)
Alcoholic Liver Diseases  (ISO)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (ISO)
amyotrophic lateral sclerosis type 1  (ISO)
angiosarcoma  (ISO)
Arteriovenous Fistula  (ISO)
arteriovenous malformations of the brain  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atrial fibrillation  (ISO)
attention deficit hyperactivity disorder  (ISO)
autoimmune hepatitis  (ISO)
Behcet's disease  (ISO)
blindness  (ISO)
brain edema  (ISO)
brain glioma  (ISO)
Brain Injuries  (ISO)
Brain Neoplasms  (ISO)
Breast Neoplasms  (ISO)
bullous pemphigoid  (ISO)
cardiomyopathy  (ISO)
Cerebral Hemorrhage  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Bronchitis  (ISO)
chronic fatigue syndrome  (ISO)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
clear cell renal cell carcinoma  (ISO)
colon cancer  (ISO)
colon carcinoma  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
congenital diaphragmatic hernia  (ISO)
congenital heart disease  (ISO)
congestive heart failure  (ISO)
contact dermatitis  (ISO)
corneal neovascularization  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
decubitus ulcer  (ISO)
dermatitis herpetiformis  (ISO)
Diabetes Complications  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
DiGeorge syndrome  (ISO)
disease of cellular proliferation  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
ductal carcinoma in situ  (ISO)
duodenal ulcer  (ISO)
Endometrial Neoplasms  (ISO)
endometriosis  (ISO)
erythema multiforme  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Neoplasms  (ISO)
extrinsic allergic alveolitis  (ISO)
gastric ulcer  (ISO)
gingivitis  (ISO)
glaucoma  (ISO)
glioblastoma  (ISO)
gliosarcoma  (ISO)
glomerulonephritis  (ISO)
Glomus Tympanicum Tumor  (ISO)
Graft vs Host Disease  (ISO)
granulosa cell tumor  (ISO)
Graves' disease  (ISO)
Head and Neck Neoplasms  (ISO)
heart disease  (ISO)
Hemorrhage  (ISO)
hepatocellular carcinoma  (ISO)
hepatopulmonary syndrome  (ISO)
Hypercholesterolemia  (ISO)
Hyperplasia  (ISO)
hypertension  (ISO)
Hypoxia-Ischemia, Brain  (ISO)
impotence  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
Invasive Pulmonary Aspergillosis  (ISO)
inverted papilloma  (ISO)
ischemic colitis  (ISO)
Kawasaki disease  (ISO)
Kuhnt-Junius degeneration  (ISO)
larynx cancer  (ISO)
learning disability  (ISO)
Limb Ischemia  (ISO)
liver cirrhosis  (ISO)
Liver Failure  (ISO)
Liver Metastasis  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (ISO)
lung non-small cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
macular degeneration  (ISO)
macular retinal edema  (ISO)
melanoma  (ISO)
Memory Disorders  (ISO)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
multiple myeloma  (ISO)
myeloid leukemia  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
nasopharynx carcinoma  (ISO)
Neoplasm Metastasis  (ISO)
Neoplasm Recurrence, Local  (ISO)
Neoplastic Cell Transformation  (ISO)
neovascular glaucoma  (ISO)
Neovascularization, Pathologic  (ISO)
Nerve Degeneration  (ISO)
neurofibromatosis 1  (ISO)
neurofibromatosis 2  (ISO)
neurofibrosarcoma  (ISO)
newborn respiratory distress syndrome  (ISO)
oral squamous cell carcinoma  (ISO)
osteochondrodysplasia  (ISO)
osteosarcoma  (ISO)
otitis media  (ISO)
Otitis Media with Effusion  (ISO)
ovarian hyperstimulation syndrome  (ISO)
Ovarian Neoplasms  (ISO)
Oxygen-Induced Retinopathy  (ISO)
pancreatic ductal carcinoma  (ISO)
Periodontal Atrophy  (ISO)
polyarteritis nodosa  (ISO)
polycystic ovary syndrome  (ISO)
Polypoidal Choroidal Vasculopathy  (ISO)
portal hypertension  (ISO)
pre-eclampsia  (ISO)
pre-malignant neoplasm  (ISO)
Pregnancy in Diabetics  (ISO)
primary biliary cholangitis  (ISO)
primary sclerosing cholangitis  (ISO)
proliferative diabetic retinopathy  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
proteinuria  (ISO)
pseudoxanthoma elasticum  (ISO)
psoriasis  (ISO)
pterygium  (ISO)
pulmonary edema  (ISO)
renal cell carcinoma  (ISO)
respiratory allergy  (ISO)
Retina Reperfusion Injury  (ISO)
retinal disease  (ISO)
retinal ischemia  (ISO)
Retinal Neovascularization  (ISO)
retinal telangiectasia  (ISO)
retinal vein occlusion  (ISO)
retinitis pigmentosa  (ISO)
retinopathy of prematurity  (ISO)
rhabdomyosarcoma  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (ISO)
Seasonal Allergic Rhinitis  (ISO)
seminoma  (ISO)
Skin Neoplasms  (ISO)
Small-For-Size Syndrome  (ISO)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
status epilepticus  (ISO)
Stroke  (ISO)
sudden infant death syndrome  (ISO)
systemic scleroderma  (ISO)
temporal lobe epilepsy  (ISO)
Thrombotic Microangiopathies  (ISO)
Tongue Neoplasms  (ISO)
Tympanic Membrane Perforation  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
Urologic Neoplasms  (ISO)
Uterine Cervical Neoplasms  (ISO)
uveal melanoma  (ISO)
Wounds and Injuries  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of protein kinase activity  (ISS)
aging  (ISO)
angiogenesis  (IEA,ISO,ISS)
angiogenesis involved in coronary vascular morphogenesis  (ISO)
apoptotic process  (ISO)
artery morphogenesis  (ISO)
basophil chemotaxis  (ISO)
blood vessel development  (ISO)
blood vessel morphogenesis  (ISO)
blood vessel remodeling  (ISO)
bone trabecula formation  (ISO)
bone trabecula morphogenesis  (ISO)
branching involved in blood vessel morphogenesis  (ISO)
branching morphogenesis of an epithelial tube  (ISO)
camera-type eye morphogenesis  (ISO)
cardiac muscle cell development  (ISO)
cardiac vascular smooth muscle cell development  (ISO)
cell chemotaxis  (ISO)
cell differentiation  (IEA)
cell migration  (ISO)
cell migration involved in sprouting angiogenesis  (ISS)
cell population proliferation  (ISO)
cell-cell adhesion  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to estrogen stimulus  (ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to hypoxia  (ISO,ISS)
cellular response to mechanical stimulus  (ISO)
cellular response to vascular endothelial growth factor stimulus  (ISS)
cellular response to wortmannin  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cellular stress response to acid chemical  (ISO)
commissural neuron axon guidance  (ISO)
coronary artery morphogenesis  (ISO)
coronary vein morphogenesis  (ISO)
dopaminergic neuron differentiation  (ISO)
endothelial cell chemotaxis  (ISS)
endothelial cell migration  (ISO)
endothelial cell proliferation  (ISO)
epithelial cell differentiation  (ISO)
epithelial cell maturation  (ISO)
epithelial cell proliferation  (ISO)
eye photoreceptor cell development  (ISO)
female pregnancy  (ISO)
heart morphogenesis  (ISO)
homeostasis of number of cells within a tissue  (ISO)
in utero embryonic development  (ISO)
induction of positive chemotaxis  (IBA)
kidney development  (ISO)
lactation  (ISO)
lung alveolus development  (ISO)
lung development  (ISO)
lung vasculature development  (ISO)
lymph vessel morphogenesis  (ISO)
lymphangiogenesis  (ISO)
macrophage differentiation  (ISS)
mammary gland alveolus development  (ISO)
mesenchymal cell proliferation  (ISO)
mesoderm development  (ISO)
monocyte differentiation  (ISS)
motor neuron migration  (ISS)
mRNA stabilization  (ISO)
negative regulation of adherens junction organization  (ISO)
negative regulation of apoptotic process  (ISO,ISS)
negative regulation of blood-brain barrier permeability  (ISO)
negative regulation of bone resorption  (ISO)
negative regulation of cell-cell adhesion  (ISO)
negative regulation of cell-cell adhesion mediated by cadherin  (ISO)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
negative regulation of epithelial to mesenchymal transition  (ISO)
negative regulation of establishment of endothelial barrier  (ISO)
negative regulation of extrinsic apoptotic signaling pathway  (ISO)
negative regulation of fat cell differentiation  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of neuron death  (ISO)
negative regulation of programmed cell death  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
nervous system development  (ISO)
neuroblast proliferation  (ISO)
neuron development  (ISO)
obsolete positive regulation of cellular component movement  (ISS)
outflow tract morphogenesis  (ISO)
ovarian follicle development  (ISO)
peptidyl-tyrosine phosphorylation  (ISO)
positive chemotaxis  (ISS)
positive regulation of angiogenesis  (IBA,ISO,ISS)
positive regulation of axon extension involved in axon guidance  (ISO)
positive regulation of blood vessel endothelial cell migration  (ISS)
positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis  (ISO)
positive regulation of branching involved in ureteric bud morphogenesis  (ISO)
positive regulation of cell adhesion  (ISS)
positive regulation of cell division  (IEA)
positive regulation of cell migration  (ISO)
positive regulation of cell migration by vascular endothelial growth factor signaling pathway  (ISO)
positive regulation of cell migration involved in sprouting angiogenesis  (ISS)
positive regulation of cell population proliferation  (ISO,ISS)
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway  (ISS)
positive regulation of cold-induced thermogenesis  (ISO)
positive regulation of CREB transcription factor activity  (ISS)
positive regulation of DNA biosynthetic process  (ISO)
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway  (ISS)
positive regulation of endothelial cell migration  (ISS)
positive regulation of endothelial cell proliferation  (IBA,ISO,ISS)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of epithelial tube formation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of focal adhesion assembly  (ISS)
positive regulation of gene expression  (ISO)
positive regulation of histone deacetylase activity  (ISO)
positive regulation of lymphangiogenesis  (ISO)
positive regulation of MAP kinase activity  (ISS)
positive regulation of MAPK cascade  (ISO)
positive regulation of mast cell chemotaxis  (IBA)
positive regulation of mesenchymal cell proliferation  (ISO)
positive regulation of neuroblast proliferation  (ISO)
positive regulation of osteoblast differentiation  (ISO)
positive regulation of p38MAPK cascade  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISS)
positive regulation of peptidyl-tyrosine autophosphorylation  (ISS)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO,ISS)
positive regulation of phosphatidylinositol 3-kinase signaling  (ISO)
positive regulation of phosphorylation  (ISO)
positive regulation of positive chemotaxis  (ISS)
positive regulation of protein autophosphorylation  (ISS)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of protein kinase C signaling  (ISS)
positive regulation of protein kinase D signaling  (ISS)
positive regulation of protein localization to early endosome  (ISO)
positive regulation of protein phosphorylation  (IBA,ISS)
positive regulation of protein-containing complex assembly  (ISS)
positive regulation of receptor internalization  (ISS)
positive regulation of retinal ganglion cell axon guidance  (ISO)
positive regulation of signal transduction  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of sprouting angiogenesis  (ISO)
positive regulation of stem cell proliferation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO,ISS)
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia  (ISO)
positive regulation of trophoblast cell migration  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
positive regulation of vascular endothelial growth factor signaling pathway  (ISO)
positive regulation of vascular permeability  (ISO)
post-embryonic camera-type eye development  (ISO)
primitive erythrocyte differentiation  (ISO)
regulation of cell shape  (ISS)
regulation of endothelial cell differentiation  (ISO)
regulation of growth  (ISO)
regulation of hematopoietic progenitor cell differentiation  (ISO)
regulation of nitric oxide mediated signal transduction  (ISO)
regulation of retinal ganglion cell axon guidance  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
response to cold  (ISO)
response to dexamethasone  (ISO)
response to estradiol  (ISO)
response to folic acid  (ISO)
response to hypoxia  (IBA,ISO,ISS)
response to oxygen levels  (ISO)
response to progesterone  (ISO)
response to vitamin A  (ISO)
signal transduction  (IEA)
sprouting angiogenesis  (IBA)
stem cell proliferation  (ISO)
surfactant homeostasis  (ISO)
T-helper 1 type immune response  (ISO)
tube formation  (ISS)
vascular endothelial growth factor receptor signaling pathway  (IBA,ISO,ISS)
vascular endothelial growth factor receptor-2 signaling pathway  (ISO)
vascular endothelial growth factor signaling pathway  (IBA)
vascular wound healing  (ISO)
vasculature development  (ISO)
vasodilation  (ISO)
VEGF-activated neuropilin signaling pathway  (ISO)
wound healing  (ISO)

Cellular Component

References
Additional References at PubMed
PMID:7841203   PMID:14998908   PMID:15274157   PMID:15537448   PMID:16333987   PMID:16365405   PMID:16372043   PMID:16538032   PMID:16584087   PMID:16967516   PMID:17120307   PMID:17310078  
PMID:17868880   PMID:17874446   PMID:18326810   PMID:19618599   PMID:20552272   PMID:20713984   PMID:20825582   PMID:21245320   PMID:22970342   PMID:24142467   PMID:24366099   PMID:24756033  
PMID:25510786   PMID:25913202   PMID:28139071   PMID:28237345   PMID:28257866   PMID:29991364   PMID:32905904   PMID:33255323   PMID:33467052  


Genomics

Comparative Map Data
VEGFA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,746,052 - 38,761,366 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,746,393 - 38,762,282 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2744,459,821 - 44,475,711 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VEGFA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38643,770,209 - 43,786,487 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl643,770,184 - 43,786,487 (+)EnsemblGRCh38hg38GRCh38
GRCh37643,737,946 - 43,754,224 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,845,931 - 43,862,202 (+)NCBINCBI36Build 36hg18NCBI36
Build 34643,845,923 - 43,860,314NCBI
Celera645,289,570 - 45,305,849 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef643,458,106 - 43,474,385 (+)NCBIHuRef
CHM1_1643,741,412 - 43,757,691 (+)NCBICHM1_1
T2T-CHM13v2.0643,599,722 - 43,616,002 (+)NCBIT2T-CHM13v2.0
Vegfa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391746,327,919 - 46,343,303 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1746,327,919 - 46,343,295 (-)EnsemblGRCm39 Ensembl
GRCm381746,016,993 - 46,032,377 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,016,993 - 46,032,369 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,153,942 - 46,169,326 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,480,574 - 45,495,331 (-)NCBIMGSCv36mm8
Celera1749,448,065 - 49,463,499 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.79NCBI
Vegfa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2914,955,300 - 14,970,641 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,955,300 - 14,970,641 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx923,540,015 - 23,555,341 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0928,602,643 - 28,617,969 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0926,903,445 - 26,918,771 (+)NCBIRnor_WKY
Rnor_6.0917,340,341 - 17,355,681 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,340,341 - 17,355,681 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,232,415 - 16,247,658 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4910,520,730 - 10,536,071 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1910,519,065 - 10,531,506 (+)NCBI
Celera912,701,425 - 12,716,765 (+)NCBICelera
Cytogenetic Map9q12NCBI
Vegfa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554379,527,445 - 9,541,908 (+)NCBIChiLan1.0ChiLan1.0
VEGFA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1644,651,855 - 44,666,353 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl644,650,365 - 44,666,353 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0643,361,053 - 43,377,366 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
VEGFA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,209,032 - 12,224,978 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,208,231 - 12,224,965 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,235,225 - 12,250,737 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01212,693,104 - 12,708,614 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1212,691,593 - 12,708,601 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,217,730 - 12,233,243 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,305,204 - 12,320,707 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,398,451 - 12,413,981 (+)NCBIUU_Cfam_GSD_1.0
Vegfa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,698,881 - 47,715,068 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647616,245,134 - 16,261,180 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VEGFA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11728,377,959 - 28,394,508 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604443,823,884 - 43,842,951 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vegfa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475415,929,414 - 15,943,637 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 5 3 3 3 2 4 2 2
Low 5 1 2 19 1 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000001892   ⟹   ENSSSCP00000001845
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl738,746,475 - 38,761,038 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000064013   ⟹   ENSSSCP00000054926
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl738,746,475 - 38,761,038 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000068911   ⟹   ENSSSCP00000068842
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl738,749,995 - 38,759,258 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000073564   ⟹   ENSSSCP00000072498
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl738,746,475 - 38,761,366 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000074202   ⟹   ENSSSCP00000063371
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl738,746,052 - 38,761,366 (+)Ensembl
RefSeq Acc Id: NM_214084   ⟹   NP_999249
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1738,747,098 - 38,760,368 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013977975   ⟹   XP_013833429
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1738,746,393 - 38,762,282 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_013833429   ⟸   XM_013977975
- Peptide Label: isoform X1
- UniProtKB: A0A4X1V7P2 (UniProtKB/TrEMBL),   A0A5G2R854 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_999249   ⟸   NM_214084
- Peptide Label: precursor
- UniProtKB: P49151 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000068842   ⟸   ENSSSCT00000068911
RefSeq Acc Id: ENSSSCP00000054926   ⟸   ENSSSCT00000064013
RefSeq Acc Id: ENSSSCP00000063371   ⟸   ENSSSCT00000074202
RefSeq Acc Id: ENSSSCP00000072498   ⟸   ENSSSCT00000073564
RefSeq Acc Id: ENSSSCP00000001845   ⟸   ENSSSCT00000001892
Protein Domains
PDGF_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000001695 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025045013 UniProtKB/TrEMBL
  ENSSSCG00030056827 UniProtKB/TrEMBL
  ENSSSCG00035074171 UniProtKB/TrEMBL
  ENSSSCG00045026256 UniProtKB/TrEMBL
  ENSSSCG00050002414 UniProtKB/TrEMBL
  ENSSSCG00055024973 UniProtKB/TrEMBL
  ENSSSCG00065074566 UniProtKB/TrEMBL
  ENSSSCG00070022200 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000001845.2 UniProtKB/TrEMBL
  ENSSSCP00000054926.1 UniProtKB/TrEMBL
  ENSSSCP00000063371.1 UniProtKB/TrEMBL
  ENSSSCP00000068842.1 UniProtKB/TrEMBL
  ENSSSCP00000072498 ENTREZGENE
  ENSSSCP00000072498.1 UniProtKB/TrEMBL
  ENSSSCP00025026340.1 UniProtKB/TrEMBL
  ENSSSCP00025026396.1 UniProtKB/TrEMBL
  ENSSSCP00025026471.1 UniProtKB/TrEMBL
  ENSSSCP00030036410.1 UniProtKB/TrEMBL
  ENSSSCP00030036428.1 UniProtKB/TrEMBL
  ENSSSCP00030036446.1 UniProtKB/TrEMBL
  ENSSSCP00035043076.1 UniProtKB/TrEMBL
  ENSSSCP00035043094.1 UniProtKB/TrEMBL
  ENSSSCP00035043120.1 UniProtKB/TrEMBL
  ENSSSCP00045031287.1 UniProtKB/TrEMBL
  ENSSSCP00045031357.1 UniProtKB/TrEMBL
  ENSSSCP00045031438.1 UniProtKB/TrEMBL
  ENSSSCP00050001048.1 UniProtKB/TrEMBL
  ENSSSCP00050001055.1 UniProtKB/TrEMBL
  ENSSSCP00050001066.1 UniProtKB/TrEMBL
  ENSSSCP00055039744.1 UniProtKB/TrEMBL
  ENSSSCP00055039814.1 UniProtKB/TrEMBL
  ENSSSCP00055039942.1 UniProtKB/TrEMBL
  ENSSSCP00065045461.1 UniProtKB/TrEMBL
  ENSSSCP00065045475.1 UniProtKB/TrEMBL
  ENSSSCP00065045482.1 UniProtKB/TrEMBL
  ENSSSCP00070037243.1 UniProtKB/TrEMBL
  ENSSSCP00070037245.1 UniProtKB/TrEMBL
  ENSSSCP00070037248.1 UniProtKB/TrEMBL
  ENSSSCP00070037254.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001892.3 UniProtKB/TrEMBL
  ENSSSCT00000064013.2 UniProtKB/TrEMBL
  ENSSSCT00000068911.1 UniProtKB/TrEMBL
  ENSSSCT00000073564 ENTREZGENE
  ENSSSCT00000073564.1 UniProtKB/TrEMBL
  ENSSSCT00000074202.1 UniProtKB/TrEMBL
  ENSSSCT00025062029.1 UniProtKB/TrEMBL
  ENSSSCT00025062165.1 UniProtKB/TrEMBL
  ENSSSCT00025062312.1 UniProtKB/TrEMBL
  ENSSSCT00030079511.1 UniProtKB/TrEMBL
  ENSSSCT00030079559.1 UniProtKB/TrEMBL
  ENSSSCT00030079610.1 UniProtKB/TrEMBL
  ENSSSCT00035101233.1 UniProtKB/TrEMBL
  ENSSSCT00035101264.1 UniProtKB/TrEMBL
  ENSSSCT00035101305.1 UniProtKB/TrEMBL
  ENSSSCT00045045113.1 UniProtKB/TrEMBL
  ENSSSCT00045045209.1 UniProtKB/TrEMBL
  ENSSSCT00045045321.1 UniProtKB/TrEMBL
  ENSSSCT00050003150.1 UniProtKB/TrEMBL
  ENSSSCT00050003164.1 UniProtKB/TrEMBL
  ENSSSCT00050003195.1 UniProtKB/TrEMBL
  ENSSSCT00055049738.1 UniProtKB/TrEMBL
  ENSSSCT00055049829.1 UniProtKB/TrEMBL
  ENSSSCT00055049993.1 UniProtKB/TrEMBL
  ENSSSCT00065102988.1 UniProtKB/TrEMBL
  ENSSSCT00065103014.1 UniProtKB/TrEMBL
  ENSSSCT00065103033.1 UniProtKB/TrEMBL
  ENSSSCT00070044211.1 UniProtKB/TrEMBL
  ENSSSCT00070044213.1 UniProtKB/TrEMBL
  ENSSSCT00070044216.1 UniProtKB/TrEMBL
  ENSSSCT00070044222.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.160.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.10.90.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PD_growth_factor_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDGF/VEGF_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VEGF_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VEGF_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397157 UniProtKB/Swiss-Prot
NCBI Gene VEGFA ENTREZGENE
Pfam PDGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VEGF_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PDGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PDGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57593 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287BFL9_PIG UniProtKB/TrEMBL
  A0A2C9F342_PIG UniProtKB/TrEMBL
  A0A4X1V7N7_PIG UniProtKB/TrEMBL
  A0A4X1V7P2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V7P8_PIG UniProtKB/TrEMBL
  A0A4X1V8U9_PIG UniProtKB/TrEMBL
  A0A5G2QHM5_PIG UniProtKB/TrEMBL
  A0A5G2R3S0_PIG UniProtKB/TrEMBL
  A0A5G2R854 ENTREZGENE, UniProtKB/TrEMBL
  P49151 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q9GL52 UniProtKB/Swiss-Prot
VGNC ID VGNC:94815 ENTREZGENE