GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | multiple interactions | EXP | | 6480464 | CTD | Losartan inhibits the reaction [Cyclosporine results in increased expression of VEGFA protein] | PMID:12110003 | Vegfa | decreases expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Losartan results in decreased expression of VEGFA mRNA; Losartan results in decreased expression of VEGFA protein | PMID:22188725 | Vegfa | multiple interactions | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Losartan inhibits the reaction [IL1A protein results in increased expression of VEGFA mRNA]; Losartan inhibits the reaction [IL1A protein results in increased expression of VEGFA protein]; Losartan inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; Losartan inhibits the reaction [TNF protein results in increased expression of VEGFA protein]; Losartan promotes the reaction [AGT protein results in increased expression of VEGFA mRNA]; Losartan promotes the reaction [AGT protein results in increased secretion of VEGFA protein] | PMID:17299153 PMID:17481528 | Vegfa | multiple interactions | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Losartan inhibits the reaction [Diethylnitrosamine results in increased expression of VEGFA protein]; Losartan inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein] | PMID:25511041 PMID:29859236 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |