Il1rl1 (interleukin 1 receptor-like 1) - Rat Genome Database

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Gene: Il1rl1 (interleukin 1 receptor-like 1) Rattus norvegicus
Analyze
Symbol: Il1rl1
Name: interleukin 1 receptor-like 1
RGD ID: 2894
Description: Predicted to enable interleukin-33 binding activity and interleukin-33 receptor activity. Involved in several processes, including cellular response to mechanical stimulus; cellular response to peptide; and negative regulation of cell population proliferation. Located in external side of plasma membrane and extracellular space. Biomarker of acute myocardial infarction and bacterial pneumonia. Human ortholog(s) of this gene implicated in asthma and coronary artery disease. Orthologous to human IL1RL1 (interleukin 1 receptor like 1); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fit-1; FIT1; Fos-responsive gene 1; Interleukin 1 receptor-like 1 (Fos-responsive gene 1); interleukin-1 receptor-like 1; St2
RGD Orthologs
Human
Mouse
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2942,661,694 - 42,727,266 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl942,697,192 - 42,727,256 (+)Ensembl
Rnor_6.0947,133,483 - 47,184,316 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl947,134,034 - 47,182,170 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0946,818,236 - 46,866,589 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4939,577,879 - 39,624,781 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1939,610,600 - 39,618,735 (+)NCBI
Celera940,421,404 - 40,468,339 (+)NCBICelera
RH 3.4 Map9420.09RGD
Cytogenetic Map9q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (EXP,ISO)
1,4-dioxane  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-D  (ISO)
2,4-diaminotoluene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-butoxyethanol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
anthracene-1,8,9-triol  (ISO)
aripiprazole  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzoic acid  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
butanal  (ISO)
butylated hydroxyanisole  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
calycosin  (EXP)
carbon monoxide  (EXP)
carbon nanotube  (ISO)
cholic acid  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (EXP)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dichlorine  (EXP)
dimethylselenide  (ISO)
dioxygen  (ISO)
endosulfan  (EXP,ISO)
ferroheme b  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
formaldehyde  (EXP)
furan  (EXP)
gentamycin  (EXP)
heme b  (ISO)
indometacin  (ISO)
iron dichloride  (ISO)
iron trichloride  (ISO)
ketoconazole  (ISO)
kojic acid  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (EXP)
methapyrilene  (EXP)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
methyltestosterone  (ISO)
Mezerein  (ISO)
Muraglitazar  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nonanoic acid  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
palytoxin  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pemetrexed  (ISO)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
phenacetin  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
progesterone  (EXP,ISO)
propionic acid  (ISO)
quercetin  (EXP,ISO)
reactive oxygen species  (ISO)
saccharin  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sodium nitrite  (ISO)
streptozocin  (EXP)
styrene oxide  (ISO)
succimer  (ISO)
sulfadimethoxine  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triptonide  (ISO)
troglitazone  (EXP,ISO)
valproic acid  (ISO)
WIN 55212-2  (EXP)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
1. Alves ABRM, etal., Med Mycol. 2018 Apr 1;56(3):332-343. doi: 10.1093/mmy/myx050.
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7. Castanhinha S, etal., J Allergy Clin Immunol. 2015 Aug;136(2):312-22.e7. doi: 10.1016/j.jaci.2015.01.016. Epub 2015 Mar 5.
8. Castano R, etal., Am J Rhinol Allergy. 2009 Jul-Aug;23(4):377-84.
9. Chuang CC, etal., J Microbiol Immunol Infect. 2016 Feb;49(1):91-6. doi: 10.1016/j.jmii.2014.01.009. Epub 2014 Mar 21.
10. Cullingford TE, etal., Biochim Biophys Acta. 2008 Jun;1783(6):1229-36. Epub 2008 Mar 25.
11. Ferreira MA, etal., Eur J Hum Genet. 2011 Apr;19(4):458-64. Epub 2010 Dec 8.
12. Franca RF, etal., J Neuroinflammation. 2016 Jun 22;13(1):159. doi: 10.1186/s12974-016-0628-1.
13. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
14. Gimenes JA, etal., Clin Sci (Lond). 2019 Apr 29;133(8):983-996. doi: 10.1042/CS20181088. Print 2019 Apr 30.
15. GOA data from the GO Consortium
16. Gudbjartsson DF, etal., Nat Genet. 2009 Mar;41(3):342-7. Epub 2009 Feb 8.
17. Hacker S, etal., J Clin Lab Anal. 2009;23(6):372-9.
18. Hayakawa H, etal., J Biol Chem. 2007 Sep 7;282(36):26369-80. Epub 2007 Jul 10.
19. Hoogerwerf JJ, etal., Am J Respir Crit Care Med. 2011 Apr 1;183(7):932-40. Epub 2010 Oct 19.
20. Huan SL, etal., BMC Infect Dis. 2016 May 16;16:200. doi: 10.1186/s12879-016-1543-x.
21. Huang SJ, etal., J Neuroinflammation. 2018 Jan 12;15(1):12. doi: 10.1186/s12974-017-1021-4.
22. Ishikawa K, etal., Auris Nasus Larynx. 2014 Dec;41(6):552-7. doi: 10.1016/j.anl.2014.08.007. Epub 2014 Sep 2.
23. Jackson-Jones LH, etal., Eur J Immunol. 2016 Oct;46(10):2311-2321. doi: 10.1002/eji.201646442.
24. Jiang SW, etal., Hepatobiliary Pancreat Dis Int. 2017 Apr;16(2):181-188. doi: 10.1016/s1499-3872(16)60185-6.
25. Kearley J, etal., Am J Respir Crit Care Med. 2009 May 1;179(9):772-81. Epub 2009 Jan 29.
26. Kulhan NG, etal., Gynecol Endocrinol. 2019 Sep;35(9):796-802. doi: 10.1080/09513590.2019.1590699. Epub 2019 Apr 2.
27. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
28. Li ZY, etal., Parasit Vectors. 2019 Jun 14;12(1):302. doi: 10.1186/s13071-019-3542-4.
29. Malcolm J, etal., J Dent Res. 2015 Jul;94(7):968-75. doi: 10.1177/0022034515577815. Epub 2015 Mar 25.
30. Mangan NE, etal., Eur J Immunol. 2007 May;37(5):1302-12.
31. Marques RE, etal., Immunology. 2018 Dec;155(4):477-490. doi: 10.1111/imm.12988. Epub 2018 Sep 10.
32. Martínez-Martínez E, etal., PLoS One. 2013 Nov 12;8(11):e79176. doi: 10.1371/journal.pone.0079176. eCollection 2013.
33. MGD data from the GO Consortium
34. Nabekura T, etal., J Immunol. 2015 Jun 15;194(12):5948-52. doi: 10.4049/jimmunol.1500424. Epub 2015 Apr 29.
35. Oshikawa K, etal., Am J Respir Crit Care Med. 2001 Jul 15;164(2):277-81.
36. Palomo J, etal., Eur J Immunol. 2015 May;45(5):1354-65. doi: 10.1002/eji.201445206. Epub 2015 Mar 20.
37. Peng C, etal., Inflammation. 2018 Jun;41(3):870-877. doi: 10.1007/s10753-018-0741-7.
38. Peng H, etal., J Infect Dis. 2013 Mar 1;207(5):860-9. doi: 10.1093/infdis/jis682. Epub 2012 Nov 12.
39. Piñeros AR, etal., Sci Rep. 2017 Jan 27;7:41240. doi: 10.1038/srep41240.
40. Ramirez-Carrozzi V, etal., J Allergy Clin Immunol. 2017 Feb;139(2):705-708.e6. doi: 10.1016/j.jaci.2016.08.026. Epub 2016 Sep 30.
41. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
42. RGD automated import pipeline for gene-chemical interactions
43. RGD comprehensive gene curation
44. Rood JE, etal., Blood. 2016 Jan 28;127(4):426-35. doi: 10.1182/blood-2015-07-659813. Epub 2015 Oct 30.
45. Ryan N, etal., Front Cell Infect Microbiol. 2020 Apr 17;10:153. doi: 10.3389/fcimb.2020.00153. eCollection 2020.
46. Sanada S, etal., J Clin Invest. 2007 Jun;117(6):1538-49. doi: 10.1172/JCI30634. Epub 2007 May 10.
47. Savenije OE, etal., J Allergy Clin Immunol. 2011 Mar;127(3):750-6.e1-5. Epub 2011 Feb 1.
48. Sedhom MA, etal., Gut. 2013 Dec;62(12):1714-23. doi: 10.1136/gutjnl-2011-301785. Epub 2012 Nov 21.
49. Seki T, etal., Parasitol Int. 2018 Feb;67(1):64-69. doi: 10.1016/j.parint.2017.03.008. Epub 2017 Mar 27.
50. Socrates T, etal., J Intern Med. 2010 Nov;268(5):493-500. doi: 10.1111/j.1365-2796.2010.02263.x.
51. Stastna M, etal., Proteomics. 2010 Jan;10(2):245-53.
52. Sánchez-Más J, etal., Eur J Clin Invest. 2014 Jul;44(7):643-51. doi: 10.1111/eci.12282.
53. Tajima S, etal., Chest. 2003 Oct;124(4):1206-14.
54. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
55. Tsapaki A, etal., J Thromb Thrombolysis. 2010 Oct;30(3):365-71.
56. Walzl G, etal., J Exp Med. 2001 Apr 2;193(7):785-92.
57. Wills-Karp M, etal., J Exp Med. 2012 Mar 12;209(3):607-22. doi: 10.1084/jem.20110079. Epub 2012 Feb 13.
58. Yamada S, etal., Clin Exp Nephrol. 2019 Apr;23(4):544-550. doi: 10.1007/s10157-018-1675-y. Epub 2018 Nov 22.
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Additional References at PubMed
PMID:7883081   PMID:12714518   PMID:14643017   PMID:18268038   PMID:19666510   PMID:19841166   PMID:19919994   PMID:25815839   PMID:27455844   PMID:28274612   PMID:29045903   PMID:29653119  
PMID:30562096   PMID:30998979   PMID:31726037   PMID:32513089   PMID:32592632  


Genomics

Comparative Map Data
Il1rl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2942,661,694 - 42,727,266 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl942,697,192 - 42,727,256 (+)Ensembl
Rnor_6.0947,133,483 - 47,184,316 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl947,134,034 - 47,182,170 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0946,818,236 - 46,866,589 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4939,577,879 - 39,624,781 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1939,610,600 - 39,618,735 (+)NCBI
Celera940,421,404 - 40,468,339 (+)NCBICelera
RH 3.4 Map9420.09RGD
Cytogenetic Map9q22NCBI
IL1RL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382102,311,563 - 102,352,356 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2102,311,502 - 102,352,037 (+)EnsemblGRCh38hg38GRCh38
GRCh372102,928,023 - 102,968,497 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362102,294,394 - 102,334,929 (+)NCBINCBI36hg18NCBI36
Build 342102,412,234 - 102,419,698NCBI
Celera297,129,200 - 97,169,642 (+)NCBI
Cytogenetic Map2q12.1NCBI
HuRef296,692,020 - 96,732,452 (+)NCBIHuRef
CHM1_12102,932,225 - 102,972,834 (+)NCBICHM1_1
T2T-CHM13v2.02102,769,846 - 102,810,316 (+)NCBI
Il1rl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39140,444,025 - 40,504,578 (+)NCBIGRCm39mm39
GRCm39 Ensembl140,468,730 - 40,504,575 (+)Ensembl
GRCm38140,404,864 - 40,465,418 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl140,429,570 - 40,465,415 (+)EnsemblGRCm38mm10GRCm38
MGSCv37140,496,494 - 40,522,260 (+)NCBIGRCm37mm9NCBIm37
MGSCv36140,384,308 - 40,409,958 (+)NCBImm8
Celera140,251,783 - 40,277,425 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map119.19NCBI
Il1rl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554707,779,828 - 7,849,157 (+)NCBIChiLan1.0ChiLan1.0
IL1RL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11040,658,191 - 40,732,097 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1040,659,041 - 40,677,357 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1040,584,086 - 40,603,254 (-)NCBI
ROS_Cfam_1.01041,524,636 - 41,543,860 (-)NCBI
ROS_Cfam_1.0 Ensembl1041,481,796 - 41,559,352 (-)Ensembl
UMICH_Zoey_3.11041,239,090 - 41,258,271 (-)NCBI
UNSW_CanFamBas_1.01041,520,373 - 41,539,587 (-)NCBI
UU_Cfam_GSD_1.01041,712,710 - 41,731,892 (-)NCBI
Il1rl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629290,097,610 - 90,128,649 (-)NCBI
SpeTri2.0NW_0049367131,020,969 - 1,035,012 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL1RL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl351,803,165 - 51,951,383 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1351,868,549 - 51,902,454 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2354,483,076 - 54,567,410 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL1RL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1145,966,551 - 6,020,391 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl146,005,061 - 6,020,265 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041173,687,571 - 173,703,287 (+)NCBIVero_WHO_p1.0
Il1rl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247496,795,748 - 6,873,701 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247496,795,822 - 6,873,068 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH94829  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,716,530 - 42,716,759 (+)MAPPERmRatBN7.2
Rnor_6.0947,173,966 - 47,174,194NCBIRnor6.0
Rnor_5.0946,858,149 - 46,858,377UniSTSRnor5.0
RGSC_v3.4939,616,577 - 39,616,805UniSTSRGSC3.4
Celera940,460,135 - 40,460,363UniSTS
RH 3.4 Map9420.09UniSTS
Cytogenetic Map9q21UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:174
Count of miRNA genes:93
Interacting mature miRNAs:105
Transcripts:ENSRNOT00000020108, ENSRNOT00000020144
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 5
Low 2 26 27 12 14 12 8 8 24 20 30 11 8
Below cutoff 15 30 29 29 2 50 15 11

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY390390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU929068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA412513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA412515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000020108   ⟹   ENSRNOP00000020108
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl942,697,192 - 42,727,256 (+)Ensembl
Rnor_6.0 Ensembl947,134,034 - 47,182,170 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000020144   ⟹   ENSRNOP00000020144
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl947,165,342 - 47,174,710 (+)Ensembl
RefSeq Acc Id: NM_001127689   ⟹   NP_001121161
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,676,675 - 42,724,735 (+)NCBI
Rnor_6.0947,134,034 - 47,182,170 (+)NCBI
Rnor_5.0946,818,236 - 46,866,589 (+)NCBI
RGSC_v3.4939,577,879 - 39,624,781 (+)RGD
Celera940,421,404 - 40,468,339 (+)RGD
Sequence:
RefSeq Acc Id: NM_013037   ⟹   NP_037169
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,708,015 - 42,717,275 (+)NCBI
Rnor_6.0947,165,342 - 47,174,710 (+)NCBI
Rnor_5.0946,818,236 - 46,866,589 (+)NCBI
RGSC_v3.4939,577,879 - 39,624,781 (+)RGD
Celera940,452,740 - 40,460,879 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244739   ⟹   XP_006244801
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,694,405 - 42,727,266 (+)NCBI
Rnor_6.0947,153,383 - 47,184,316 (+)NCBI
Rnor_5.0946,818,236 - 46,866,589 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244740   ⟹   XP_006244802
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,676,497 - 42,727,266 (+)NCBI
Rnor_6.0947,133,483 - 47,184,316 (+)NCBI
Rnor_5.0946,818,236 - 46,866,589 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008766992   ⟹   XP_008765214
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,676,497 - 42,727,266 (+)NCBI
Rnor_6.0947,133,483 - 47,184,316 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596290   ⟹   XP_017451779
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,706,543 - 42,727,266 (+)NCBI
Rnor_6.0947,163,939 - 47,184,316 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083070   ⟹   XP_038938998
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,661,694 - 42,727,266 (+)NCBI
RefSeq Acc Id: XM_039083071   ⟹   XP_038938999
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,694,405 - 42,727,266 (+)NCBI
RefSeq Acc Id: XM_039083072   ⟹   XP_038939000
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,661,694 - 42,727,266 (+)NCBI
RefSeq Acc Id: XM_039083073   ⟹   XP_038939001
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,707,740 - 42,727,266 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_037169   ⟸   NM_013037
- Peptide Label: isoform Fit-1S precursor
- UniProtKB: Q62611 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001121161   ⟸   NM_001127689
- Peptide Label: isoform Fit-1M precursor
- UniProtKB: Q62611 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006244802   ⟸   XM_006244740
- Peptide Label: isoform X1
- UniProtKB: F1LR63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244801   ⟸   XM_006244739
- Peptide Label: isoform X1
- UniProtKB: F1LR63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765214   ⟸   XM_008766992
- Peptide Label: isoform X1
- UniProtKB: F1LR63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451779   ⟸   XM_017596290
- Peptide Label: isoform X1
- UniProtKB: F1LR63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000020144   ⟸   ENSRNOT00000020144
RefSeq Acc Id: ENSRNOP00000020108   ⟸   ENSRNOT00000020108
RefSeq Acc Id: XP_038938998   ⟸   XM_039083070
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038939000   ⟸   XM_039083072
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038938999   ⟸   XM_039083071
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038939001   ⟸   XM_039083073
- Peptide Label: isoform X1
Protein Domains
Ig-like   Ig-like C2-type   TIR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62611-F1-model_v2 AlphaFold Q62611 1-566 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696631
Promoter ID:EPDNEW_R7156
Type:single initiation site
Name:Il1rl1_1
Description:interleukin 1 receptor-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0947,165,343 - 47,165,403EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
9 47166983 47166984 G T snv CDR, WN/N (2020), WN/N (MCW)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
9 46851210 46851211 G T snv WN/N (KNAW), BDIX.Cg-Tal/NemOda (KyushuU), BDIX/NemOda (KyushuU)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
9 42709656 42709657 G T snv WN/N (2020)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2894 AgrOrtholog
BioCyc Gene G2FUF-27723 BioCyc
Ensembl Genes ENSRNOG00000014835 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000020108 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000020144 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020108 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000020144 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.10140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_rcpt_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_rcpt_I/II-typ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25556 UniProtKB/Swiss-Prot
NCBI Gene 25556 ENTREZGENE
PANTHER PTHR11890 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ig_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB IL1RL1 RGD
PhenoGen Il1rl1 PhenoGen
PRINTS INTRLKN1R12F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC211924
UniProt F1LR56_RAT UniProtKB/TrEMBL
  F1LR63 ENTREZGENE, UniProtKB/TrEMBL
  ILRL1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q62612 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Il1rl1  interleukin 1 receptor-like 1      Symbol and Name updated 629477 APPROVED
2003-03-12 Il1rl1  interleukin 1 receptor-like 1  St2  Fos-responsive gene 1  Data Merged 628472 PROVISIONAL
2002-06-10 St2  Fos-responsive gene 1      Symbol and Name status set to approved 70586 APPROVED
2002-06-10 Il1rl1  interleukin 1 receptor-like 1      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_transcript differential promoter usage creates two alternative transcipts 69859
gene_transcript alternative mRNAs encode for a transmembrane protein and a soluable secreted protein 69859