Il1rl1 (interleukin 1 receptor-like 1) - Rat Genome Database

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Gene: Il1rl1 (interleukin 1 receptor-like 1) Mus musculus
Analyze
Symbol: Il1rl1
Name: interleukin 1 receptor-like 1
RGD ID: 736159
MGI Page MGI
Description: Enables interleukin-33 binding activity. Involved in several processes, including macrophage differentiation; positive regulation of macrophage activation; and regulation of cytokine production. Located in external side of plasma membrane. Is expressed in several structures, including immune system; musculoskeletal system; salivary gland; skin; and visual system. Human ortholog(s) of this gene implicated in asthma and coronary artery disease. Orthologous to human IL1RL1 (interleukin 1 receptor like 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DER; DER4; Fit-; Fit-1; interleukin-1 receptor-like 1; interleukin-33 receptor alpha chain; Ly8; Ly84; lymphocyte antigen 84; ST; St2; St2-; St2-rs1; ST2L; T1; T1/ST; T1/ST2
RGD Orthologs
Human
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39140,444,025 - 40,504,578 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl140,468,730 - 40,504,575 (+)EnsemblGRCm39 Ensembl
GRCm38140,404,864 - 40,465,418 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl140,429,570 - 40,465,415 (+)EnsemblGRCm38mm10GRCm38
MGSCv37140,496,494 - 40,522,260 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36140,384,308 - 40,409,958 (+)NCBIMGSCv36mm8
Celera140,251,783 - 40,277,425 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map119.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1,4-dioxane  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-D  (ISO)
2,4-diaminotoluene  (EXP)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-butoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3-methylcholanthrene  (EXP)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
7,12-dimethyltetraphene  (EXP,ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (ISO)
anthracene-1,8,9-triol  (EXP)
aripiprazole  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzoic acid  (EXP)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
butanal  (ISO)
butylated hydroxyanisole  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (EXP)
calcitriol  (ISO)
calycosin  (ISO)
carbon monoxide  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
cholic acid  (EXP)
chromium(6+)  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (EXP,ISO)
dichlorine  (ISO)
dimethylselenide  (ISO)
dioxygen  (ISO)
endosulfan  (ISO)
ferroheme b  (EXP)
flavonoids  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (ISO)
gentamycin  (ISO)
heme b  (EXP)
indometacin  (ISO)
iron dichloride  (EXP)
iron trichloride  (EXP)
ketoconazole  (ISO)
kojic acid  (EXP)
lipopolysaccharide  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
methyltestosterone  (ISO)
Mezerein  (EXP)
Muraglitazar  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nonanoic acid  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
palytoxin  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pemetrexed  (ISO)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
phenacetin  (EXP)
phenobarbital  (EXP,ISO)
phorbol 13-acetate 12-myristate  (EXP)
pirinixic acid  (ISO)
progesterone  (EXP,ISO)
propionic acid  (EXP)
quercetin  (ISO)
reactive oxygen species  (ISO)
saccharin  (EXP)
serpentine asbestos  (EXP,ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sodium nitrite  (EXP)
streptozocin  (ISO)
styrene oxide  (EXP)
succimer  (EXP)
sulfadimethoxine  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (EXP)
triptonide  (EXP)
troglitazone  (EXP,ISO)
valproic acid  (EXP,ISO)
WIN 55212-2  (ISO)
zinc dichloride  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Differential production of interleukin-1 family cytokines (IL-1β, IL-18, IL-33 and IL-37) in patients with paracoccidioidomycosis: correlation with clinical form and antifungal therapy. Alves ABRM, etal., Med Mycol. 2018 Apr 1;56(3):332-343. doi: 10.1093/mmy/myx050.
2. The Alarmin IL-33 Derived from HSV-2-Infected Keratinocytes Triggers Mast Cell-Mediated Antiviral Innate Immunity. Aoki R, etal., J Invest Dermatol. 2016 Jun;136(6):1290-1292. doi: 10.1016/j.jid.2016.01.030. Epub 2016 Feb 9.
3. IL-33 receptor (ST2) deficiency downregulates myeloid precursors, inflammatory NK and dendritic cells in early phase of sepsis. Babic ZM, etal., J Biomed Sci. 2018 Jul 12;25(1):56. doi: 10.1186/s12929-018-0455-z.
4. T-bet- and STAT4-dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses. Baumann C, etal., Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4056-61. doi: 10.1073/pnas.1418549112. Epub 2015 Mar 17.
5. Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor. Bergers G, etal., EMBO J 1994 Mar 1;13(5):1176-88.
6. Asthma and genes encoding components of the vitamin D pathway. Bosse Y, etal., Respir Res. 2009 Oct 24;10:98.
7. Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33. Castanhinha S, etal., J Allergy Clin Immunol. 2015 Aug;136(2):312-22.e7. doi: 10.1016/j.jaci.2015.01.016. Epub 2015 Mar 5.
8. Evidence of association of interleukin-1 receptor-like 1 gene polymorphisms with chronic rhinosinusitis. Castano R, etal., Am J Rhinol Allergy. 2009 Jul-Aug;23(4):377-84.
9. Anti-ST2 monoclonal antibody inhibits eosinophil infiltration in Angiostrongylus cantonensis-infected mice. Chuang CC, etal., J Microbiol Immunol Infect. 2016 Feb;49(1):91-6. doi: 10.1016/j.jmii.2014.01.009. Epub 2014 Mar 21.
10. Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. Ferreira MA, etal., Eur J Hum Genet. 2011 Apr;19(4):458-64. Epub 2010 Dec 8.
11. IL-33 signaling is essential to attenuate viral-induced encephalitis development by downregulating iNOS expression in the central nervous system. Franca RF, etal., J Neuroinflammation. 2016 Jun 22;13(1):159. doi: 10.1186/s12974-016-0628-1.
12. Rhinovirus-induces progression of lung disease in a mouse model of COPD via IL-33/ST2 signaling axis. Gimenes JA, etal., Clin Sci (Lond). 2019 Apr 29;133(8):983-996. doi: 10.1042/CS20181088. Print 2019 Apr 30.
13. Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Gudbjartsson DF, etal., Nat Genet. 2009 Mar;41(3):342-7. Epub 2009 Feb 8.
14. Increased soluble serum markers caspase-cleaved cytokeratin-18, histones, and ST2 indicate apoptotic turnover and chronic immune response in COPD. Hacker S, etal., J Clin Lab Anal. 2009;23(6):372-9.
15. Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation. Hayakawa H, etal., J Biol Chem. 2007 Sep 7;282(36):26369-80. Epub 2007 Jul 10.
16. Loss of suppression of tumorigenicity 2 (ST2) gene reverses sepsis-induced inhibition of lung host defense in mice. Hoogerwerf JJ, etal., Am J Respir Crit Care Med. 2011 Apr 1;183(7):932-40. Epub 2010 Oct 19.
17. Relevance of serum interleukin-33 and ST2 levels and the natural course of chronic hepatitis B virus infection. Huan SL, etal., BMC Infect Dis. 2016 May 16;16:200. doi: 10.1186/s12879-016-1543-x.
18. IL-33/ST2 signaling contributes to radicular pain by modulating MAPK and NF-κB activation and inflammatory mediator expression in the spinal cord in rat models of noncompressive lumber disk herniation. Huang SJ, etal., J Neuroinflammation. 2018 Jan 12;15(1):12. doi: 10.1186/s12974-017-1021-4.
19. Expression of interleukin-33 is correlated with poor prognosis of patients with squamous cell carcinoma of the tongue. Ishikawa K, etal., Auris Nasus Larynx. 2014 Dec;41(6):552-7. doi: 10.1016/j.anl.2014.08.007. Epub 2014 Sep 2.
20. IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha. Jackson-Jones LH, etal., Eur J Immunol. 2016 Oct;46(10):2311-2321. doi: 10.1002/eji.201646442.
21. Serum soluble ST2 is a promising prognostic biomarker in HBV-related acute-on-chronic liver failure. Jiang SW, etal., Hepatobiliary Pancreat Dis Int. 2017 Apr;16(2):181-188. doi: 10.1016/s1499-3872(16)60185-6.
22. Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathway. Kearley J, etal., Am J Respir Crit Care Med. 2009 May 1;179(9):772-81. Epub 2009 Jan 29.
23. Could interleukin-33 and its suppressor of tumorigenicity 2 (ST2) receptor have a role in cervical human papillomavirus (HPV) infections? Kulhan NG, etal., Gynecol Endocrinol. 2019 Sep;35(9):796-802. doi: 10.1080/09513590.2019.1590699. Epub 2019 Apr 2.
24. Contribution of tissue transglutaminase to the severity of hepatic fibrosis resulting from Schistosoma japonicum infection through the regulation of IL-33/ST2 expression. Li ZY, etal., Parasit Vectors. 2019 Jun 14;12(1):302. doi: 10.1186/s13071-019-3542-4.
25. IL-33 Exacerbates Periodontal Disease through Induction of RANKL. Malcolm J, etal., J Dent Res. 2015 Jul;94(7):968-75. doi: 10.1177/0022034515577815. Epub 2015 Mar 25.
26. T1/ST2 expression on Th2 cells negatively regulates allergic pulmonary inflammation. Mangan NE, etal., Eur J Immunol. 2007 May;37(5):1302-12.
27. Interleukin-33 contributes to disease severity in Dengue virus infection in mice. Marques RE, etal., Immunology. 2018 Dec;155(4):477-490. doi: 10.1111/imm.12988. Epub 2018 Sep 10.
28. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
29. MGDs mouse GO annotations MGD data from the GO Consortium
30. MGD IEA MGD IEA
31. IL-33 receptor ST2 amplifies the expansion of NK cells and enhances host defense during mouse cytomegalovirus infection. Nabekura T, etal., J Immunol. 2015 Jun 15;194(12):5948-52. doi: 10.4049/jimmunol.1500424. Epub 2015 Apr 29.
32. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
33. Elevated soluble ST2 protein levels in sera of patients with asthma with an acute exacerbation. Oshikawa K, etal., Am J Respir Crit Care Med. 2001 Jul 15;164(2):277-81.
34. Critical role of IL-33 receptor ST2 in experimental cerebral malaria development. Palomo J, etal., Eur J Immunol. 2015 May;45(5):1354-65. doi: 10.1002/eji.201445206. Epub 2015 Mar 20.
35. IL-33 Treatment Attenuates the Systemic Inflammation Reaction in Acinetobacter baumannii Pneumonia by Suppressing TLR4/NF-κB Signaling. Peng C, etal., Inflammation. 2018 Jun;41(3):870-877. doi: 10.1007/s10753-018-0741-7.
36. Interleukin 33 mediates type 2 immunity and inflammation in the central nervous system of mice infected with Angiostrongylus cantonensis. Peng H, etal., J Infect Dis. 2013 Mar 1;207(5):860-9. doi: 10.1093/infdis/jis682. Epub 2012 Nov 12.
37. M2 macrophages or IL-33 treatment attenuate ongoing Mycobacterium tuberculosis infection. Piñeros AR, etal., Sci Rep. 2017 Jan 27;7:41240. doi: 10.1038/srep41240.
38. Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone. Ramirez-Carrozzi V, etal., J Allergy Clin Immunol. 2017 Feb;139(2):705-708.e6. doi: 10.1016/j.jaci.2016.08.026. Epub 2016 Sep 30.
39. Mouse MP Annotation Import Pipeline RGD automated import pipeline
40. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
41. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
42. ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice. Rood JE, etal., Blood. 2016 Jan 28;127(4):426-35. doi: 10.1182/blood-2015-07-659813. Epub 2015 Oct 30.
43. The IL-33/ST2 Axis in Immune Responses Against Parasitic Disease: Potential Therapeutic Applications. Ryan N, etal., Front Cell Infect Microbiol. 2020 Apr 17;10:153. doi: 10.3389/fcimb.2020.00153. eCollection 2020.
44. IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system. Sanada S, etal., J Clin Invest. 2007 Jun;117(6):1538-49. doi: 10.1172/JCI30634. Epub 2007 May 10.
45. Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood. Savenije OE, etal., J Allergy Clin Immunol. 2011 Mar;127(3):750-6.e1-5. Epub 2011 Feb 1.
46. Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice. Sedhom MA, etal., Gut. 2013 Dec;62(12):1714-23. doi: 10.1136/gutjnl-2011-301785. Epub 2012 Nov 21.
47. IL-33/ST2 contributes to severe symptoms in Plasmodium chabaudi-infected BALB/c mice. Seki T, etal., Parasitol Int. 2018 Feb;67(1):64-69. doi: 10.1016/j.parint.2017.03.008. Epub 2017 Mar 27.
48. Interleukin family member ST2 and mortality in acute dyspnoea. Socrates T, etal., J Intern Med. 2010 Nov;268(5):493-500. doi: 10.1111/j.1365-2796.2010.02263.x.
49. Modulation of IL-33/ST2 system in postinfarction heart failure: correlation with cardiac remodelling markers. Sánchez-Más J, etal., Eur J Clin Invest. 2014 Jul;44(7):643-51. doi: 10.1111/eci.12282.
50. The increase in serum soluble ST2 protein upon acute exacerbation of idiopathic pulmonary fibrosis. Tajima S, etal., Chest. 2003 Oct;124(4):1206-14.
51. Genetic variability of the distal promoter of the ST2 gene is associated with angiographic severity of coronary artery disease. Tsapaki A, etal., J Thromb Thrombolysis. 2010 Oct;30(3):365-71.
52. Inhibition of T1/ST2 during respiratory syncytial virus infection prevents T helper cell type 2 (Th2)- but not Th1-driven immunopathology. Walzl G, etal., J Exp Med. 2001 Apr 2;193(7):785-92.
53. Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection. Wills-Karp M, etal., J Exp Med. 2012 Mar 12;209(3):607-22. doi: 10.1084/jem.20110079. Epub 2012 Feb 13.
54. Interleukin-33/ST2 signaling contributes to the severity of hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coli. Yamada S, etal., Clin Exp Nephrol. 2019 Apr;23(4):544-550. doi: 10.1007/s10157-018-1675-y. Epub 2018 Nov 22.
55. Adenovirus-mediated overexpression of soluble ST2 provides a protective effect on lipopolysaccharide-induced acute lung injury in mice. Yin H, etal., Clin Exp Immunol. 2011 May;164(2):248-55. doi: 10.1111/j.1365-2249.2011.04326.x. Epub 2011 Feb 24.
56. IL-33/ST2 correlates with severity of haemorrhagic fever with renal syndrome and regulates the inflammatory response in Hantaan virus-infected endothelial cells. Zhang Y, etal., PLoS Negl Trop Dis. 2015 Feb 6;9(2):e0003514. doi: 10.1371/journal.pntd.0003514. eCollection 2015 Feb.
Additional References at PubMed
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PMID:21515798   PMID:21623379   PMID:21640974   PMID:21646790   PMID:21674479   PMID:21677750   PMID:21703183   PMID:21873635   PMID:21911606   PMID:21949025   PMID:22198948   PMID:22278120  
PMID:22323740   PMID:22361513   PMID:22542450   PMID:22585447   PMID:22585662   PMID:22634619   PMID:22660580   PMID:22990621   PMID:23028861   PMID:23071771   PMID:23093619   PMID:23142275  
PMID:23169007   PMID:23300625   PMID:23324173   PMID:23347081   PMID:23404570   PMID:23420878   PMID:23483993   PMID:23523996   PMID:23536294   PMID:23585480   PMID:23633023   PMID:23733876  
PMID:23810766   PMID:23837438   PMID:23856919   PMID:23894196   PMID:23935505   PMID:23945235   PMID:23954132   PMID:23988433   PMID:24045639   PMID:24068673   PMID:24105680   PMID:24210353  
PMID:24323357   PMID:24344271   PMID:24470502   PMID:24508233   PMID:24551140   PMID:24631157   PMID:24663677   PMID:24663956   PMID:24866242   PMID:24982172   PMID:24985397   PMID:25015831  
PMID:25043027   PMID:25116404   PMID:25472995   PMID:25531830   PMID:25595464   PMID:25599561   PMID:25661185   PMID:25681338   PMID:25692703   PMID:25693767   PMID:25721734   PMID:25786179  
PMID:25814531   PMID:25863247   PMID:25941360   PMID:26011644   PMID:26044350   PMID:26092469   PMID:26129648   PMID:26200013   PMID:26272906   PMID:26277897   PMID:26310268   PMID:26314835  
PMID:26322482   PMID:26352378   PMID:26365875   PMID:26417439   PMID:26428949   PMID:26473724   PMID:26555705   PMID:26609909   PMID:26755704   PMID:26872699   PMID:26942077   PMID:27067050  
PMID:27091974   PMID:27102638   PMID:27184849   PMID:27222019   PMID:27340126   PMID:27358001   PMID:27453471   PMID:27548066   PMID:27568595   PMID:27569535   PMID:27582256   PMID:27683753  
PMID:27701734   PMID:27749840   PMID:27821781   PMID:27882929   PMID:27994070   PMID:28194023   PMID:28198366   PMID:28228256   PMID:28259547   PMID:28374774   PMID:28383552   PMID:28389473  
PMID:28448566   PMID:28448579   PMID:28450225   PMID:28476932   PMID:28532656   PMID:28538175   PMID:28656964   PMID:28747424   PMID:28784844   PMID:28798029   PMID:28869965   PMID:28869974  
PMID:28878285   PMID:28916390   PMID:29045902   PMID:29045903   PMID:29132961   PMID:29133293   PMID:29222107   PMID:29249358   PMID:29288203   PMID:29420261   PMID:29436517   PMID:29674622  
PMID:29722022   PMID:29867945   PMID:29887374   PMID:29907525   PMID:29988569   PMID:30011081   PMID:30192340   PMID:30201992   PMID:30224451   PMID:30318149   PMID:30337928   PMID:30446569  
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PMID:30988052   PMID:31027995   PMID:31053654   PMID:31053655   PMID:31057534   PMID:31061143   PMID:31087583   PMID:31112061   PMID:31165767   PMID:31221971   PMID:31235844   PMID:31391233  
PMID:31455422   PMID:31591231   PMID:31640262   PMID:31656879   PMID:31674275   PMID:31801068   PMID:31812341   PMID:31844326   PMID:31911623   PMID:31988179   PMID:32026128   PMID:32101749  
PMID:32102434   PMID:32108542   PMID:32130902   PMID:32160524   PMID:32160525   PMID:32268121   PMID:32272082   PMID:32292403   PMID:32296080   PMID:32340025   PMID:32366846   PMID:32393354  
PMID:32408242   PMID:32410845   PMID:32484881   PMID:32554809   PMID:32571430   PMID:32582171   PMID:32615087   PMID:32644975   PMID:32989331   PMID:33095261   PMID:33108405   PMID:33204337  
PMID:33220232   PMID:33594087   PMID:33596932   PMID:33815420   PMID:33902297   PMID:34170196   PMID:34290377   PMID:34305899   PMID:34324507   PMID:34354077   PMID:34638904   PMID:34644537  
PMID:34650552   PMID:34752815   PMID:34982959   PMID:35150208   PMID:35378447   PMID:35432343   PMID:35608240   PMID:35709757   PMID:35908617   PMID:35909659   PMID:35940987   PMID:36044899  
PMID:36463230  


Genomics

Comparative Map Data
Il1rl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39140,444,025 - 40,504,578 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl140,468,730 - 40,504,575 (+)EnsemblGRCm39 Ensembl
GRCm38140,404,864 - 40,465,418 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl140,429,570 - 40,465,415 (+)EnsemblGRCm38mm10GRCm38
MGSCv37140,496,494 - 40,522,260 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36140,384,308 - 40,409,958 (+)NCBIMGSCv36mm8
Celera140,251,783 - 40,277,425 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map119.19NCBI
IL1RL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382102,311,563 - 102,352,356 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2102,311,502 - 102,352,037 (+)EnsemblGRCh38hg38GRCh38
GRCh372102,928,023 - 102,968,497 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362102,294,394 - 102,334,929 (+)NCBINCBI36Build 36hg18NCBI36
Build 342102,412,234 - 102,419,698NCBI
Celera297,129,200 - 97,169,642 (+)NCBICelera
Cytogenetic Map2q12.1NCBI
HuRef296,692,020 - 96,732,452 (+)NCBIHuRef
CHM1_12102,932,225 - 102,972,834 (+)NCBICHM1_1
T2T-CHM13v2.02102,769,846 - 102,810,316 (+)NCBIT2T-CHM13v2.0
Il1rl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2942,661,694 - 42,727,266 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl942,697,192 - 42,727,256 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx951,179,169 - 51,227,104 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0956,301,859 - 56,349,792 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0954,577,363 - 54,625,421 (+)NCBIRnor_WKY
Rnor_6.0947,133,483 - 47,184,316 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl947,134,034 - 47,182,170 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0946,818,236 - 46,866,589 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4939,577,879 - 39,624,781 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1939,610,600 - 39,618,735 (+)NCBI
Celera940,421,404 - 40,468,339 (+)NCBICelera
RH 3.4 Map9420.09RGD
Cytogenetic Map9q22NCBI
Il1rl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554707,779,828 - 7,849,157 (+)NCBIChiLan1.0ChiLan1.0
IL1RL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11040,658,191 - 40,732,097 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1040,659,041 - 40,677,357 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1040,584,086 - 40,603,254 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01041,524,636 - 41,543,860 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1041,481,796 - 41,559,352 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11041,239,090 - 41,258,271 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01041,520,373 - 41,539,587 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01041,712,710 - 41,731,892 (-)NCBIUU_Cfam_GSD_1.0
Il1rl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629290,097,610 - 90,128,649 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367131,021,044 - 1,035,039 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049367131,020,969 - 1,035,012 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL1RL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl351,846,792 - 51,951,383 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1351,868,549 - 51,902,454 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2354,483,076 - 54,567,410 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL1RL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1145,966,551 - 6,020,391 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl146,005,061 - 6,020,265 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041173,687,571 - 173,703,287 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il1rl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247496,795,748 - 6,873,701 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247496,795,822 - 6,873,068 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5288
Count of miRNA genes:906
Interacting mature miRNAs:1323
Transcripts:ENSMUST00000053043, ENSMUST00000097772, ENSMUST00000173514, ENSMUST00000173881, ENSMUST00000174335
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1301011Cplaq4_mcircadian period of locomotor activity 4 (mouse)Not determined1967344243673601Mouse
14700685Civq2_mcerebral infarct volume QTL 2 (mouse)11134048245340482Mouse
1301073Orch5_mautoimmune orchitis resistance 5 (mouse)Not determined11906535153065454Mouse
1301756Pgia1_mproteoglycan induced arthritis 1 (mouse)Not determined11906535153065454Mouse
1301240Sluc15_msusceptibility to lung cancer 15 (mouse)Not determined11906535153065454Mouse
12880407V125Dq2_mvitamin D active form serum level QTL 2 (mouse)11933908153339081Mouse
1357475w3q13_mweight 3 weeks QTL 13 (mouse)Not determined12310959173976915Mouse
4142433Hbnr1_mHeligmosomoides bakeri nematode resistance 1 (mouse)Not determined2555019158273271Mouse
11100001Col4a1m1_mcollagen, type IV, alpha 1 modifier 1 (mouse)12555019162946882Mouse
12880409V125Dq1_mvitamin D active form serum level QTL 1 (mouse)12603916060039160Mouse
1357824Estoq4_membryo survival total QTL 4 (mouse)Not determined13476013873976915Mouse
39128207Lwq16_mliver weight QTL 16 (mouse)13476013873976915Mouse
1357759W3q12_mweight 3 weeks QTL 12 (mouse)Not determined13476013873976915Mouse
1357651Lgq5_mlate growth QTL 5 (mouse)Not determined13476013873976915Mouse
1357506W10q6_mweight 10 weeks QTL 6 (mouse)Not determined13476013873976915Mouse
1357524W6q14_mweight 6 weeks QTL 14 (mouse)Not determined13476013873976915Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
1301954Lrnx11_mlearning-contextual 11 (mouse)Not determined13913280874516365Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
14700785Syncq2_msynovial calcification QTL 2 (mouse)13969616040499160Mouse

Markers in Region
D13695  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38140,462,802 - 40,462,899UniSTSGRCm38
MGSCv37140,519,647 - 40,519,744UniSTSGRCm37
Celera140,274,812 - 40,274,909UniSTS
Cytogenetic Map1BUniSTS
cM Map120.0UniSTS
Whitehead/MRC_RH1634.17UniSTS
M24843  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38140,446,802 - 40,446,992UniSTSGRCm38
MGSCv37140,503,647 - 40,503,837UniSTSGRCm37
Celera140,258,860 - 40,259,050UniSTS
Cytogenetic Map1BUniSTS
cM Map120.0UniSTS
Whitehead_YAC1 UniSTS
D866  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38140,446,190 - 40,446,341UniSTSGRCm38
MGSCv37140,503,035 - 40,503,186UniSTSGRCm37
Celera140,258,252 - 40,258,399UniSTS
Cytogenetic Map1BUniSTS
cM Map120.6UniSTS
Whitehead Genetic119.7UniSTS
D1Mit122.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38140,446,118 - 40,446,228UniSTSGRCm38
MGSCv37140,502,963 - 40,503,073UniSTSGRCm37
Celera140,258,180 - 40,258,290UniSTS
Cytogenetic Map1BUniSTS
cM Map120.6UniSTS
cM Map1 UniSTS
Whitehead Genetic120.3634UniSTS
Whitehead_YAC1 UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001294171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006495741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006495744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC167126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC167168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI573400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC033416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY228016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D13695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M24843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U38789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X77497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y07519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000053043   ⟹   ENSMUSP00000054914
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl140,479,788 - 40,504,556 (+)Ensembl
GRCm38.p6 Ensembl140,440,628 - 40,465,396 (+)Ensembl
RefSeq Acc Id: ENSMUST00000097772   ⟹   ENSMUSP00000095379
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl140,478,787 - 40,504,575 (+)Ensembl
GRCm38.p6 Ensembl140,439,627 - 40,465,415 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173514   ⟹   ENSMUSP00000133784
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl140,478,936 - 40,487,308 (+)Ensembl
GRCm38.p6 Ensembl140,439,776 - 40,448,148 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173881   ⟹   ENSMUSP00000134225
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl140,475,749 - 40,480,567 (+)Ensembl
GRCm38.p6 Ensembl140,436,589 - 40,441,407 (+)Ensembl
RefSeq Acc Id: ENSMUST00000174335   ⟹   ENSMUSP00000134351
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl140,468,730 - 40,485,883 (+)Ensembl
GRCm38.p6 Ensembl140,429,570 - 40,446,723 (+)Ensembl
RefSeq Acc Id: NM_001025602   ⟹   NP_001020773
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39140,478,789 - 40,504,575 (+)NCBI
GRCm38140,439,629 - 40,465,415 (+)NCBI
MGSCv37140,496,494 - 40,522,260 (+)RGD
Celera140,241,707 - 40,277,425 (+)NCBI
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001294171   ⟹   NP_001281100
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39140,468,730 - 40,487,571 (+)NCBI
GRCm38140,429,570 - 40,448,411 (+)NCBI
Celera140,241,707 - 40,277,425 (+)NCBI
Sequence:
RefSeq Acc Id: NM_010743   ⟹   NP_034873
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39140,478,789 - 40,487,571 (+)NCBI
GRCm38140,439,629 - 40,448,411 (+)NCBI
MGSCv37140,496,494 - 40,522,260 (+)RGD
Celera140,241,707 - 40,277,425 (+)NCBI
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006495741   ⟹   XP_006495804
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39140,468,693 - 40,504,578 (+)NCBI
GRCm38140,429,533 - 40,465,418 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006495744   ⟹   XP_006495807
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39140,444,025 - 40,504,578 (+)NCBI
GRCm38140,404,864 - 40,465,418 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036162498   ⟹   XP_036018391
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39140,444,025 - 40,504,578 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034873   ⟸   NM_010743
- Peptide Label: isoform b precursor
- UniProtKB: P14719 (UniProtKB/Swiss-Prot),   Q5D095 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020773   ⟸   NM_001025602
- Peptide Label: isoform a precursor
- UniProtKB: Q05208 (UniProtKB/Swiss-Prot),   P14719 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006495807   ⟸   XM_006495744
- Peptide Label: isoform X1
- UniProtKB: Q05208 (UniProtKB/Swiss-Prot),   P14719 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006495804   ⟸   XM_006495741
- Peptide Label: isoform X1
- UniProtKB: Q05208 (UniProtKB/Swiss-Prot),   P14719 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001281100   ⟸   NM_001294171
- Peptide Label: isoform b precursor
- UniProtKB: P14719 (UniProtKB/Swiss-Prot),   Q5D095 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000054914   ⟸   ENSMUST00000053043
RefSeq Acc Id: ENSMUSP00000134351   ⟸   ENSMUST00000174335
RefSeq Acc Id: ENSMUSP00000133784   ⟸   ENSMUST00000173514
RefSeq Acc Id: ENSMUSP00000134225   ⟸   ENSMUST00000173881
RefSeq Acc Id: ENSMUSP00000095379   ⟸   ENSMUST00000097772
RefSeq Acc Id: XP_036018391   ⟸   XM_036162498
- Peptide Label: isoform X1
- UniProtKB: Q05208 (UniProtKB/Swiss-Prot)
Protein Domains
Ig-like   Ig-like C2-type   TIR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P14719-F1-model_v2 AlphaFold P14719 1-567 view protein structure

Promoters
RGD ID:6873562
Promoter ID:EPDNEW_M232
Type:multiple initiation site
Name:Il1rl1_1
Description:Mus musculus interleukin 1 receptor-like 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M233  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38140,429,576 - 40,429,636EPDNEW
RGD ID:6873564
Promoter ID:EPDNEW_M233
Type:multiple initiation site
Name:Il1rl1_2
Description:Mus musculus interleukin 1 receptor-like 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M232  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38140,439,776 - 40,439,836EPDNEW
RGD ID:6817937
Promoter ID:MM_KWN:561
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4
Transcripts:NM_010743,   UC007AUB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36140,496,441 - 40,496,941 (+)MPROMDB
RGD ID:6817939
Promoter ID:MM_KWN:562
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4,   MEF_B6
Transcripts:NM_001025602
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36140,496,846 - 40,497,592 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98427 AgrOrtholog
Ensembl Genes ENSMUSG00000026069 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000054914 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000095379 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000133784 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000134225.2 UniProtKB/TrEMBL
  ENSMUSP00000134351 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000053043 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000097772 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000173514 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000173881.8 UniProtKB/TrEMBL
  ENSMUST00000174335 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.10140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_rcpt_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_rcpt_I/II-typ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17082 UniProtKB/Swiss-Prot
MGD MGI:98427 ENTREZGENE
NCBI Gene 17082 ENTREZGENE
PANTHER PTHR11890 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB IL1RL1 RGD
PhenoGen Il1rl1 PhenoGen
PRINTS INTRLKN1R12F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3UYU3_MOUSE UniProtKB/TrEMBL
  ILRL1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q05208 ENTREZGENE
  Q3UM53_MOUSE UniProtKB/TrEMBL
  Q5D095 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q05208 UniProtKB/Swiss-Prot