(-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1348975 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of RUNX2 mRNA CTD PMID:22079256 (20S)-ginsenoside Rg3 multiple interactions EXP 6480464 ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]] more ... CTD PMID:27387537 (R)-camphor affects expression ISO RGD:735753 6480464 Camphor analog affects the expression of RUNX2 mRNA CTD PMID:24704097 1,4-benzoquinone increases expression ISO RGD:1348975 6480464 quinone results in increased expression of RUNX2 mRNA CTD PMID:22960397 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO RGD:735753 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:30529163 15-deoxy-Delta(12,14)-prostaglandin J2 decreases expression ISO RGD:735753 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 results in decreased expression of RUNX2 mRNA CTD PMID:12021203 17beta-estradiol multiple interactions ISO RGD:1348975 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of RUNX2 mRNA more ... CTD PMID:17689939 more ... 17beta-estradiol increases expression ISO RGD:735753 6480464 Estradiol results in increased expression of RUNX2 protein CTD PMID:31225646 17beta-estradiol increases expression ISO RGD:1348975 6480464 Estradiol results in increased expression of RUNX2 mRNA CTD PMID:16202921 more ... 17beta-estradiol affects expression ISO RGD:735753 6480464 Estradiol affects the expression of RUNX2 mRNA CTD PMID:17166402 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:735753 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:735753 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:735753 6480464 Tetrachlorodibenzodioxin results in decreased expression of RUNX2 mRNA CTD PMID:19264158 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1348975 6480464 Tetrachlorodibenzodioxin affects the expression of RUNX2 mRNA, Tetrachlorodibenzodioxin affects the expression of RUNX2 protein CTD PMID:30203000 , PMID:31887333 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RUNX2 mRNA CTD PMID:27913140 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1348975 6480464 Tetrachlorodibenzodioxin results in increased expression of RUNX2 mRNA CTD PMID:22903824 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1348975 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RUNX2 mRNA] CTD PMID:23625689 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:735753 6480464 Tetrachlorodibenzodioxin affects the expression of RUNX2 mRNA CTD PMID:24704097 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735753 6480464 Tetrachlorodibenzodioxin results in increased expression of RUNX2 mRNA CTD PMID:17586704 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of RUNX2 mRNA CTD PMID:19201780 , PMID:19264158 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:735753 6480464 AHR protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of RUNX2 mRNA], Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to RUNX2 gene] CTD PMID:19264158 , PMID:20819909 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2-amino-2-deoxy-D-glucopyranose increases phosphorylation ISO RGD:1348975 6480464 Glucosamine analog results in increased phosphorylation of RUNX2 protein CTD PMID:20458730 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:1348975 6480464 Glucosamine analog results in increased expression of RUNX2 mRNA CTD PMID:20458730 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:1348975 6480464 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein] CTD PMID:20458730 2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid multiple interactions ISO RGD:1348975 6480464 anacardic acid inhibits the reaction [Tretinoin results in increased expression of RUNX2 mRNA] CTD PMID:24819975 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions ISO RGD:735753 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 2-trans,6-trans-farnesyl diphosphate multiple interactions ISO RGD:735753 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 3,3',5,5'-tetrabromobisphenol A decreases expression ISO RGD:735753 6480464 tetrabromobisphenol A results in decreased expression of RUNX2 mRNA CTD PMID:25777084 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:735753 6480464 bisindolylmaleimide I inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA] CTD PMID:12403780 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of RUNX2 mRNA CTD PMID:28522335 4,4'-sulfonyldiphenol increases expression ISO RGD:735753 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of RUNX2 mRNA CTD PMID:30951980 5-fluorouracil affects expression ISO RGD:735753 6480464 Fluorouracil affects the expression of RUNX2 mRNA CTD PMID:24704097 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 DDIT3 protein affects the reaction [6-chloro-2 more ... CTD PMID:29653943 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide decreases expression EXP 6480464 6-chloro-2 more ... CTD PMID:29653943 acetamide increases expression EXP 6480464 acetamide results in increased expression of RUNX2 mRNA CTD PMID:31881176 adenine multiple interactions EXP 6480464 [Phosphates co-treated with Adenine] results in increased expression of RUNX2 mRNA, linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of RUNX2 mRNA] CTD PMID:30466616 aflatoxin B1 decreases methylation ISO RGD:1348975 6480464 Aflatoxin B1 results in decreased methylation of RUNX2 gene CTD PMID:27153756 aflatoxin B1 increases expression ISO RGD:1348975 6480464 Aflatoxin B1 results in increased expression of RUNX2 mRNA CTD PMID:32234424 aflatoxin B1 increases methylation ISO RGD:1348975 6480464 Aflatoxin B1 results in increased methylation of RUNX2 intron CTD PMID:30157460 aldehydo-D-glucosamine increases phosphorylation ISO RGD:1348975 6480464 Glucosamine analog results in increased phosphorylation of RUNX2 protein CTD PMID:20458730 aldehydo-D-glucosamine increases expression ISO RGD:1348975 6480464 Glucosamine analog results in increased expression of RUNX2 mRNA CTD PMID:20458730 aldehydo-D-glucosamine multiple interactions ISO RGD:1348975 6480464 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein] CTD PMID:20458730 aldehydo-D-glucose increases expression ISO RGD:735753 6480464 Glucose results in increased expression of RUNX2 mRNA CTD PMID:17178593 aldehydo-D-glucose multiple interactions ISO RGD:1348975 6480464 [EPO protein co-treated with Glucose] results in increased expression of RUNX2 mRNA, [EPO protein co-treated with Glucose] results in increased expression of RUNX2 protein CTD PMID:30894315 alendronic acid multiple interactions EXP 6480464 Alendronate promotes the reaction [modafinil results in increased expression of RUNX2 mRNA] CTD PMID:29649498 all-trans-retinoic acid increases expression ISO RGD:735753 6480464 Tretinoin results in increased expression of RUNX2 mRNA CTD PMID:16350840 all-trans-retinoic acid increases expression ISO RGD:1348975 6480464 Tretinoin results in increased expression of RUNX2 mRNA CTD PMID:21934132 , PMID:24819975 all-trans-retinoic acid multiple interactions ISO RGD:1348975 6480464 anacardic acid inhibits the reaction [Tretinoin results in increased expression of RUNX2 mRNA], ginkgolic acid inhibits the reaction [Tretinoin results in increased expression of RUNX2 mRNA] CTD PMID:24819975 all-trans-retinoic acid decreases expression ISO RGD:1348975 6480464 Tretinoin results in decreased expression of RUNX2 mRNA CTD PMID:15498508 all-trans-retinol multiple interactions ISO RGD:735753 6480464 [Cryptoxanthins co-treated with Vitamin A] results in increased expression of RUNX2 mRNA CTD PMID:15962303 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of RUNX2 mRNA CTD PMID:16483693 ammonium chloride multiple interactions ISO RGD:1348975 6480464 Ammonium Chloride inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:23111315 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 [pyrazolanthrone co-treated with SB 203580 co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA] CTD PMID:26136938 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1348975 6480464 pyrazolanthrone inhibits the reaction [Ethanol results in increased activity of RUNX2 protein] CTD PMID:32198086 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:735753 6480464 pyrazolanthrone inhibits the reaction [tanshinone results in increased expression of RUNX2 protein] CTD PMID:31306638 apocynin multiple interactions EXP 6480464 acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA] CTD PMID:24080574 arsane affects methylation ISO RGD:1348975 6480464 Arsenic affects the methylation of RUNX2 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1348975 6480464 Arsenic affects the methylation of RUNX2 gene CTD PMID:25304211 arsenite(3-) increases methylation ISO RGD:1348975 6480464 arsenite results in increased methylation of RUNX2 promoter CTD PMID:23974009 arsenous acid multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in decreased expression of RUNX2] CTD PMID:24531206 arsenous acid decreases expression ISO RGD:1348975 6480464 Arsenic Trioxide results in decreased expression of RUNX2 mRNA CTD PMID:20458559 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of RUNX2, Arsenic Trioxide results in decreased expression of RUNX2 mRNA CTD PMID:22465848 , PMID:24531206 azadirachtin A multiple interactions ISO RGD:735753 6480464 ESR1 protein promotes the reaction [azadirachtin results in increased expression of RUNX2 mRNA], ESR1 protein promotes the reaction [azadirachtin results in increased expression of RUNX2 protein] CTD PMID:31225646 azadirachtin A increases expression ISO RGD:735753 6480464 azadirachtin results in increased expression of RUNX2 mRNA, azadirachtin results in increased expression of RUNX2 protein CTD PMID:31225646 bafilomycin A1 multiple interactions ISO RGD:1348975 6480464 bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:23111315 benzene decreases expression ISO RGD:735753 6480464 Benzene results in decreased expression of RUNX2 mRNA CTD PMID:15120971 benzene increases expression ISO RGD:1348975 6480464 Benzene results in increased expression of RUNX2 mRNA CTD PMID:22960397 benzo[a]pyrene increases methylation ISO RGD:735753 6480464 Benzo(a)pyrene results in increased methylation of RUNX2 3' UTR, Benzo(a)pyrene results in increased methylation of RUNX2 exon CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:735753 6480464 Benzo(a)pyrene affects the methylation of RUNX2 intron CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:1348975 6480464 Benzo(a)pyrene results in increased methylation of RUNX2 3' UTR CTD PMID:27901495 benzo[a]pyrene decreases methylation ISO RGD:1348975 6480464 Benzo(a)pyrene results in decreased methylation of RUNX2 promoter CTD PMID:27901495 benzo[a]pyrene diol epoxide I affects expression ISO RGD:1348975 6480464 7 more ... CTD PMID:20382639 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1348975 6480464 7 more ... CTD PMID:19150397 berberine multiple interactions ISO RGD:1348975 6480464 CTNNB1 mutant form inhibits the reaction [Berberine results in increased expression of RUNX2 mRNA], DKK1 protein inhibits the reaction [Berberine results in increased expression of RUNX2 mRNA] CTD PMID:26478571 berberine increases expression ISO RGD:1348975 6480464 Berberine results in increased expression of RUNX2 mRNA CTD PMID:26478571 beta-D-glucosamine increases phosphorylation ISO RGD:1348975 6480464 Glucosamine analog results in increased phosphorylation of RUNX2 protein CTD PMID:20458730 beta-D-glucosamine increases expression ISO RGD:1348975 6480464 Glucosamine analog results in increased expression of RUNX2 mRNA CTD PMID:20458730 beta-D-glucosamine multiple interactions ISO RGD:1348975 6480464 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein] CTD PMID:20458730 bezafibrate increases expression ISO RGD:735753 6480464 Bezafibrate results in increased expression of RUNX2 mRNA CTD PMID:21499286 bezafibrate multiple interactions ISO RGD:735753 6480464 dorsomorphin inhibits the reaction [Bezafibrate results in increased expression of RUNX2 mRNA], GSK0660 inhibits the reaction [Bezafibrate results in increased expression of RUNX2 mRNA] CTD PMID:21499286 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of RUNX2 mRNA, Diethylhexyl Phthalate results in decreased expression of RUNX2 protein CTD PMID:22985736 , PMID:29945229 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1348975 6480464 Diethylhexyl Phthalate results in increased expression of RUNX2 mRNA CTD PMID:31163220 bisphenol A decreases expression ISO RGD:735753 6480464 bisphenol A results in decreased expression of RUNX2 mRNA CTD PMID:23900028 bisphenol A multiple interactions EXP 6480464 TGFB1 protein inhibits the reaction [bisphenol A results in decreased expression of RUNX2 mRNA] CTD PMID:34097993 bisphenol A increases expression ISO RGD:1348975 6480464 bisphenol A analog results in increased expression of RUNX2 mRNA, bisphenol A results in increased expression of RUNX2 mRNA CTD PMID:32387340 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of RUNX2 mRNA CTD PMID:30816183 bisphenol A increases expression ISO RGD:735753 6480464 bisphenol A results in increased expression of RUNX2 mRNA CTD PMID:30951980 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of RUNX2 gene CTD PMID:28505145 bisphenol A affects methylation ISO RGD:735753 6480464 bisphenol A affects the methylation of RUNX2 promoter CTD PMID:27334623 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of RUNX2 mRNA CTD PMID:25181051 , PMID:34097993 Bisphenol B increases expression ISO RGD:1348975 6480464 bisphenol B results in increased expression of RUNX2 mRNA CTD PMID:32387340 bisphenol F increases expression ISO RGD:735753 6480464 bisphenol F results in increased expression of RUNX2 mRNA CTD PMID:30951980 boric acid affects expression ISO RGD:735753 6480464 boric acid affects the expression of RUNX2 mRNA CTD PMID:24704097 Butylparaben decreases expression ISO RGD:735753 6480464 butylparaben results in decreased expression of RUNX2 mRNA CTD PMID:28527915 C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of RUNX2 mRNA CTD PMID:19167457 cadmium atom decreases expression ISO RGD:1348975 6480464 Cadmium results in decreased expression of RUNX2 mRNA CTD PMID:20570719 cadmium atom multiple interactions ISO RGD:1348975 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RUNX2 mRNA more ... CTD PMID:32522577 cadmium dichloride decreases expression ISO RGD:1348975 6480464 Cadmium Chloride results in decreased expression of RUNX2, Cadmium Chloride results in decreased expression of RUNX2 mRNA CTD PMID:19017541 more ... cadmium dichloride multiple interactions ISO RGD:1348975 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RUNX2 mRNA more ... CTD PMID:19017541 , PMID:32522577 caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of RUNX2 mRNA CTD PMID:30423288 , PMID:31874197 calcidiol increases expression ISO RGD:1348975 6480464 Calcifediol results in increased expression of RUNX2 mRNA CTD PMID:21542014 calcidiol multiple interactions ISO RGD:1348975 6480464 CYP27B1 protein promotes the reaction [Calcifediol results in increased expression of RUNX2 mRNA], Ketoconazole inhibits the reaction [Calcifediol results in increased expression of RUNX2 mRNA] CTD PMID:21542014 calciol multiple interactions ISO RGD:1348975 6480464 [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA more ... CTD PMID:17692823 , PMID:22940495 calcitriol multiple interactions ISO RGD:1348975 6480464 Calcitriol promotes the reaction [VDR protein binds to RUNX2 enhancer] CTD PMID:17293108 calcitriol increases expression ISO RGD:1348975 6480464 Calcitriol results in increased expression of RUNX2 mRNA CTD PMID:21542014 , PMID:28105418 calcitriol decreases expression ISO RGD:1348975 6480464 Calcitriol results in decreased expression of RUNX2 mRNA CTD PMID:16002434 , PMID:26485663 calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of RUNX2 protein CTD PMID:19092814 calcitriol decreases expression ISO RGD:735753 6480464 Calcitriol results in decreased expression of RUNX2 mRNA CTD PMID:17293108 camphor affects expression ISO RGD:735753 6480464 Camphor analog affects the expression of RUNX2 mRNA CTD PMID:24704097 cannabidiol increases expression ISO RGD:1348975 6480464 Cannabidiol results in increased expression of RUNX2 protein CTD PMID:32656944 captopril multiple interactions ISO RGD:735753 6480464 Captopril promotes the reaction [LEPR protein affects the expression of RUNX2 mRNA] CTD PMID:28130181 celecoxib multiple interactions ISO RGD:735753 6480464 [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 mRNA, [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 protein CTD PMID:27050768 CHIR 99021 increases expression ISO RGD:735753 6480464 Chir 99021 results in increased expression of RUNX2 mRNA CTD PMID:32220932 chitosan increases expression ISO RGD:1348975 6480464 Chitosan results in increased expression of RUNX2 mRNA, Chitosan results in increased expression of RUNX2 protein CTD PMID:25246786 chloroacetaldehyde decreases expression ISO RGD:1348975 6480464 chloroacetaldehyde results in decreased expression of RUNX2 mRNA CTD PMID:25596134 chloroquine multiple interactions ISO RGD:1348975 6480464 Chloroquine inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:23111315 chlorpyrifos multiple interactions EXP 6480464 [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of RUNX2 mRNA CTD PMID:27905518 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of RUNX2 mRNA CTD PMID:27905518 choline multiple interactions ISO RGD:735753 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RUNX2 mRNA CTD PMID:20938992 chromium(3+) trichloride multiple interactions ISO RGD:735753 6480464 [cobaltous chloride co-treated with chromic chloride] affects the expression of RUNX2 mRNA CTD PMID:25966675 cidofovir anhydrous increases expression ISO RGD:1348975 6480464 Cidofovir results in increased expression of RUNX2 mRNA CTD PMID:25596134 cisplatin affects expression ISO RGD:1348975 6480464 Cisplatin affects the expression of RUNX2 mRNA CTD PMID:25596134 cisplatin multiple interactions ISO RGD:1348975 6480464 Cisplatin promotes the reaction [jinfukang results in decreased expression of RUNX2 mRNA], jinfukang promotes the reaction [Cisplatin results in decreased expression of RUNX2 mRNA] CTD PMID:27392435 cisplatin decreases expression ISO RGD:1348975 6480464 Cisplatin results in decreased expression of RUNX2 mRNA CTD PMID:27392435 clodronic acid increases expression ISO RGD:1348975 6480464 Clodronic Acid results in increased expression of RUNX2 mRNA CTD PMID:25596134 cobalt dichloride decreases expression ISO RGD:735753 6480464 cobaltous chloride results in decreased expression of RUNX2 mRNA CTD PMID:16772336 cobalt dichloride multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of RUNX2 mRNA] more ... CTD PMID:31472278 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of RUNX2 mRNA, cobaltous chloride results in increased expression of RUNX2 protein CTD PMID:31472278 cobalt dichloride affects expression ISO RGD:735753 6480464 cobaltous chloride affects the expression of RUNX2 mRNA CTD PMID:25966675 cobalt dichloride multiple interactions ISO RGD:735753 6480464 [cobaltous chloride co-treated with chromic chloride] affects the expression of RUNX2 mRNA CTD PMID:25966675 cocaine multiple interactions EXP 6480464 [Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to DNM1L promoter] more ... CTD PMID:30158054 colforsin daropate hydrochloride increases expression EXP 6480464 Colforsin results in increased expression of RUNX2 mRNA CTD PMID:20197312 copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of RUNX2 mRNA CTD PMID:26033743 copper atom multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of RUNX2 mRNA CTD PMID:26033743 copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of RUNX2 mRNA CTD PMID:26033743 copper(0) multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of RUNX2 mRNA CTD PMID:26033743 corticosterone multiple interactions EXP 6480464 Enalapril inhibits the reaction [Corticosterone results in decreased expression of RUNX2 mRNA] CTD PMID:30423288 corticosterone decreases expression EXP 6480464 Corticosterone results in decreased expression of RUNX2 mRNA CTD PMID:30423288 crocidolite asbestos increases expression ISO RGD:1348975 6480464 Asbestos, Crocidolite results in increased expression of RUNX2 mRNA CTD PMID:18687144 curcumin decreases expression ISO RGD:1348975 6480464 Curcumin results in decreased expression of RUNX2 protein CTD PMID:15129424 cycloheximide multiple interactions ISO RGD:735753 6480464 Cycloheximide inhibits the reaction [Cryptoxanthins results in increased expression of RUNX2 mRNA], Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA] CTD PMID:15962303 , PMID:18327666 D-glucose increases expression ISO RGD:735753 6480464 Glucose results in increased expression of RUNX2 mRNA CTD PMID:17178593 D-glucose multiple interactions ISO RGD:1348975 6480464 [EPO protein co-treated with Glucose] results in increased expression of RUNX2 mRNA, [EPO protein co-treated with Glucose] results in increased expression of RUNX2 protein CTD PMID:30894315 DDT increases expression ISO RGD:1348975 6480464 DDT results in increased expression of RUNX2 mRNA CTD PMID:25014179 desferrioxamine B decreases expression ISO RGD:735753 6480464 Deferoxamine results in decreased expression of RUNX2 mRNA CTD PMID:16772336 dexamethasone multiple interactions ISO RGD:735753 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA] more ... CTD PMID:26492236 more ... dexamethasone decreases expression ISO RGD:735753 6480464 Dexamethasone results in decreased expression of RUNX2 protein CTD PMID:30878453 dexamethasone multiple interactions EXP 6480464 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA more ... CTD PMID:24239970 more ... dexamethasone multiple interactions ISO RGD:1348975 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA more ... CTD PMID:22940495 more ... dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of RUNX2 mRNA, Dexamethasone results in decreased expression of RUNX2 protein CTD PMID:27387537 , PMID:28363435 dexamethasone decreases expression ISO RGD:1348975 6480464 Dexamethasone results in decreased expression of RUNX2 mRNA CTD PMID:25047013 dexamethasone affects expression EXP 6480464 Dexamethasone affects the expression of RUNX2 mRNA CTD PMID:24239970 diarsenic trioxide multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in decreased expression of RUNX2] CTD PMID:24531206 diarsenic trioxide decreases expression ISO RGD:1348975 6480464 Arsenic Trioxide results in decreased expression of RUNX2 mRNA CTD PMID:20458559 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of RUNX2, Arsenic Trioxide results in decreased expression of RUNX2 mRNA CTD PMID:22465848 , PMID:24531206 diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of RUNX2 mRNA CTD PMID:30723492 dioxygen decreases expression ISO RGD:1348975 6480464 Oxygen deficiency results in decreased expression of RUNX2 mRNA CTD PMID:25596134 disodium selenite multiple interactions ISO RGD:735753 6480464 [Dexamethasone co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in decreased expression of RUNX2 protein more ... CTD PMID:32324263 disulfiram increases expression EXP 6480464 Disulfiram results in increased expression of RUNX2 mRNA CTD PMID:24496638 dorsomorphin multiple interactions ISO RGD:735753 6480464 dorsomorphin inhibits the reaction [Bezafibrate results in increased expression of RUNX2 mRNA] CTD PMID:21499286 dorsomorphin multiple interactions ISO RGD:1348975 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:23111315 , PMID:27188386 enalapril multiple interactions EXP 6480464 Enalapril inhibits the reaction [Corticosterone results in decreased expression of RUNX2 mRNA], Enalapril inhibits the reaction [Ethanol results in decreased expression of RUNX2 mRNA] CTD PMID:30423288 , PMID:31887396 ethanol multiple interactions ISO RGD:735753 6480464 [Genistein co-treated with Ethanol] results in increased expression of RUNX2 mRNA, [Genistein co-treated with Ethanol] results in increased expression of RUNX2 protein CTD PMID:24872432 ethanol multiple interactions EXP 6480464 Enalapril inhibits the reaction [Ethanol results in decreased expression of RUNX2 mRNA] CTD PMID:31887396 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of RUNX2 mRNA CTD PMID:31887396 ethanol increases expression ISO RGD:1348975 6480464 Ethanol results in increased expression of RUNX2 mRNA CTD PMID:32198086 ethanol multiple interactions ISO RGD:1348975 6480464 ESR1 promotes the reaction [Ethanol results in increased expression of and results in increased activity of RUNX2 protein] more ... CTD PMID:32198086 Ethoxyacetic acid affects expression ISO RGD:735753 6480464 ethoxyacetic acid affects the expression of RUNX2 mRNA CTD PMID:24704097 Ethylenethiourea multiple interactions EXP 6480464 [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of RUNX2 mRNA CTD PMID:27905518 farnesyl diphosphate multiple interactions ISO RGD:735753 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 fasudil multiple interactions ISO RGD:735753 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA] more ... CTD PMID:31935364 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of RUNX2 mRNA CTD PMID:16543677 , PMID:23238999 folic acid multiple interactions ISO RGD:735753 6480464 [Folic Acid co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein more ... CTD PMID:20938992 , PMID:32324263 fulvestrant multiple interactions ISO RGD:1348975 6480464 fulvestrant inhibits the reaction [Estradiol results in increased expression of RUNX2 mRNA] more ... CTD PMID:17689939 , PMID:26362186 fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [naringin results in increased expression of RUNX2 mRNA] CTD PMID:23596885 gallocatechin increases expression EXP 6480464 gallocatechol results in increased expression of RUNX2 mRNA CTD PMID:21877759 gamma-aminobutyric acid affects expression EXP 6480464 gamma-Aminobutyric Acid affects the expression of RUNX2 mRNA CTD PMID:24098073 gamma-Oryzanol (TN) affects expression EXP 6480464 gamma-oryzanol affects the expression of RUNX2 mRNA CTD PMID:24098073 genistein affects expression ISO RGD:735753 6480464 Genistein affects the expression of RUNX2 mRNA CTD PMID:17166402 genistein increases expression EXP 6480464 Genistein results in increased expression of RUNX2 mRNA CTD PMID:21877759 genistein increases expression ISO RGD:735753 6480464 Genistein results in increased expression of RUNX2 mRNA, Genistein results in increased expression of RUNX2 protein CTD PMID:24872432 genistein multiple interactions ISO RGD:735753 6480464 [Genistein co-treated with Ethanol] results in increased expression of RUNX2 mRNA, [Genistein co-treated with Ethanol] results in increased expression of RUNX2 protein CTD PMID:24872432 Ginkgoic acid multiple interactions ISO RGD:1348975 6480464 ginkgolic acid inhibits the reaction [Tretinoin results in increased expression of RUNX2 mRNA] CTD PMID:24819975 ginsenoside Rb1 increases expression EXP 6480464 ginsenoside Rb1 results in increased expression of RUNX2 mRNA CTD PMID:27470910 ginsenoside Rb1 multiple interactions EXP 6480464 ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of RUNX2 mRNA] CTD PMID:27470910 glucose increases expression ISO RGD:735753 6480464 Glucose results in increased expression of RUNX2 mRNA CTD PMID:17178593 glucose multiple interactions ISO RGD:1348975 6480464 [EPO protein co-treated with Glucose] results in increased expression of RUNX2 mRNA, [EPO protein co-treated with Glucose] results in increased expression of RUNX2 protein CTD PMID:30894315 glycerol 2-phosphate multiple interactions ISO RGD:1348975 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA more ... CTD PMID:17692823 more ... glycerol 2-phosphate multiple interactions ISO RGD:735753 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA] more ... CTD PMID:26492236 more ... glycerol 2-phosphate multiple interactions EXP 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein more ... CTD PMID:27028516 , PMID:27387537 glycidol increases expression EXP 6480464 glycidol results in increased expression of RUNX2 mRNA CTD PMID:24915197 glycyrrhetinate multiple interactions ISO RGD:735753 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein] more ... CTD PMID:21910061 glycyrrhetinic acid multiple interactions ISO RGD:735753 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein] more ... CTD PMID:21910061 hexaconazole affects expression ISO RGD:735753 6480464 hexaconazole affects the expression of RUNX2 mRNA CTD PMID:24704097 hexadecanoic acid increases expression EXP 6480464 Palmitic Acid results in increased expression of RUNX2 mRNA CTD PMID:24080574 hexadecanoic acid multiple interactions EXP 6480464 acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA] more ... CTD PMID:24080574 hydrogen chloride increases expression ISO RGD:1348975 6480464 Hydrochloric Acid results in increased expression of RUNX2 mRNA, Hydrochloric Acid results in increased expression of RUNX2 protein CTD PMID:17183249 hydrogen peroxide multiple interactions ISO RGD:1348975 6480464 DKK1 protein inhibits the reaction [naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]], naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA] CTD PMID:26482937 hydrogen peroxide multiple interactions EXP 6480464 Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA], Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]] CTD PMID:27028516 hydrogen peroxide decreases expression ISO RGD:1348975 6480464 Hydrogen Peroxide results in decreased expression of RUNX2 mRNA CTD PMID:26482937 hydroquinone increases expression ISO RGD:1348975 6480464 hydroquinone results in increased expression of RUNX2 mRNA CTD PMID:22960397 hydroxyurea affects expression ISO RGD:735753 6480464 Hydroxyurea affects the expression of RUNX2 mRNA CTD PMID:24704097 icariin increases expression ISO RGD:735753 6480464 icariin results in increased expression of RUNX2 mRNA CTD PMID:18295595 , PMID:19747809 icariin increases expression EXP 6480464 icariin results in increased expression of RUNX2 mRNA CTD PMID:20019778 icariin multiple interactions ISO RGD:735753 6480464 NOG protein inhibits the reaction [icariin results in increased expression of RUNX2 mRNA] CTD PMID:18295595 , PMID:19747809 Indeno[1,2,3-cd]pyrene increases expression ISO RGD:1348975 6480464 indeno(1 more ... CTD PMID:32251684 indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RUNX2 mRNA CTD PMID:22129741 ionomycin multiple interactions ISO RGD:735753 6480464 Ionomycin affects the reaction [CALR protein affects the expression of RUNX2 mRNA] CTD PMID:32220932 isonicotinamide increases expression ISO RGD:1348975 6480464 isonicotinamide results in increased expression of RUNX2 mRNA CTD PMID:21745208 kaempferol increases expression ISO RGD:735753 6480464 kaempferol results in increased expression of RUNX2 mRNA CTD PMID:23989061 ketoconazole multiple interactions ISO RGD:1348975 6480464 Ketoconazole inhibits the reaction [Calcifediol results in increased expression of RUNX2 mRNA] CTD PMID:21542014 L-ascorbic acid multiple interactions ISO RGD:1348975 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA more ... CTD PMID:17692823 , PMID:26424790 L-ascorbic acid multiple interactions EXP 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein more ... CTD PMID:21613385 more ... L-ascorbic acid increases expression ISO RGD:1348975 6480464 Ascorbic Acid results in increased expression of RUNX2 mRNA CTD PMID:28105418 L-ascorbic acid multiple interactions ISO RGD:735753 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA] more ... CTD PMID:20530736 more ... L-ascorbic acid increases expression ISO RGD:735753 6480464 Ascorbic Acid results in increased expression of RUNX2 mRNA CTD PMID:20530736 L-ascorbic acid 2-phosphate multiple interactions ISO RGD:1348975 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of RUNX2 mRNA more ... CTD PMID:22940495 , PMID:23111315 L-methionine multiple interactions ISO RGD:735753 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RUNX2 mRNA CTD PMID:20938992 lead nitrate multiple interactions ISO RGD:735753 6480464 [lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 mRNA more ... CTD PMID:30731080 lead(0) decreases expression ISO RGD:735753 6480464 Lead results in decreased expression of RUNX2 mRNA CTD PMID:23086611 lead(0) multiple interactions ISO RGD:735753 6480464 [lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 mRNA more ... CTD PMID:30731080 lead(0) decreases expression EXP 6480464 Lead results in decreased expression of RUNX2 mRNA, Lead results in decreased expression of RUNX2 protein CTD PMID:23086611 lead(2+) decreases expression ISO RGD:735753 6480464 Lead results in decreased expression of RUNX2 mRNA CTD PMID:23086611 lead(2+) multiple interactions ISO RGD:735753 6480464 [lead nitrate results in increased abundance of Lead] which results in decreased expression of RUNX2 mRNA more ... CTD PMID:30731080 lead(2+) decreases expression EXP 6480464 Lead results in decreased expression of RUNX2 mRNA, Lead results in decreased expression of RUNX2 protein CTD PMID:23086611 Licochalcone B decreases expression ISO RGD:1348975 6480464 licochalcone B results in decreased expression of RUNX2 mRNA CTD PMID:33647349 linalool multiple interactions EXP 6480464 linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of RUNX2 mRNA] CTD PMID:30466616 losartan multiple interactions EXP 6480464 Losartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 mRNA], Losartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 protein] CTD PMID:27412937 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of RUNX2 mRNA CTD PMID:28801915 melatonin increases expression ISO RGD:1348975 6480464 Melatonin results in increased expression of RUNX2 mRNA CTD PMID:20738756 menaquinone increases expression EXP 6480464 Vitamin K 2 results in increased expression of RUNX2 protein CTD PMID:30639440 menaquinone multiple interactions EXP 6480464 PTH protein promotes the reaction [Vitamin K 2 results in increased expression of RUNX2 protein], Vitamin K 2 affects the reaction [PTH protein results in increased expression of RUNX2 protein] CTD PMID:30639440 mercury dibromide multiple interactions ISO RGD:1348975 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA CTD PMID:27188386 metformin increases expression EXP 6480464 Metformin results in increased expression of RUNX2 protein CTD PMID:19594306 methotrexate decreases response to substance ISO RGD:1348975 6480464 RUNX2 mRNA results in decreased susceptibility to Methotrexate CTD PMID:20008919 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of RUNX2 gene CTD PMID:23303685 methoxychlor decreases expression EXP 6480464 Methoxychlor results in decreased expression of RUNX2 mRNA CTD PMID:23303685 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of RUNX2 mRNA CTD PMID:31378766 methylparaben decreases expression ISO RGD:735753 6480464 methylparaben results in decreased expression of RUNX2 mRNA CTD PMID:28527915 mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of RUNX2 mRNA CTD PMID:20197312 modafinil increases expression EXP 6480464 modafinil results in increased expression of RUNX2 mRNA CTD PMID:29649498 modafinil multiple interactions EXP 6480464 Alendronate promotes the reaction [modafinil results in increased expression of RUNX2 mRNA] CTD PMID:29649498 mono(2-ethylhexyl) phthalate decreases expression ISO RGD:735753 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of RUNX2 mRNA CTD PMID:22401849 , PMID:25777084 Monobutylphthalate affects expression ISO RGD:735753 6480464 monobutyl phthalate affects the expression of RUNX2 mRNA CTD PMID:24704097 montelukast increases expression ISO RGD:735753 6480464 montelukast results in increased expression of RUNX2 mRNA CTD PMID:19544365 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO RGD:735753 6480464 [zinc chloride co-treated with N more ... CTD PMID:19913120 N-acetyl-L-cysteine multiple interactions ISO RGD:1348975 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of RUNX2 mRNA] CTD PMID:19017541 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Dexamethasone affects the expression of RUNX2 mRNA] CTD PMID:24239970 N-nitrosodiethylamine increases expression ISO RGD:735753 6480464 Diethylnitrosamine results in increased expression of RUNX2 mRNA CTD PMID:24535843 N-nitrosodiethylamine multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RUNX2 mRNA CTD PMID:22129741 naringin multiple interactions EXP 6480464 fulvestrant inhibits the reaction [naringin results in increased expression of RUNX2 mRNA] CTD PMID:23596885 naringin multiple interactions ISO RGD:735753 6480464 naringin inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 protein] CTD PMID:30878453 naringin multiple interactions ISO RGD:1348975 6480464 DKK1 protein inhibits the reaction [naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]], naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA] CTD PMID:26482937 naringin increases expression ISO RGD:735753 6480464 naringin results in increased expression of RUNX2 mRNA CTD PMID:21741227 naringin increases expression EXP 6480464 naringin results in increased expression of RUNX2 mRNA CTD PMID:23596885 naringin increases expression ISO RGD:1348975 6480464 naringin results in increased expression of RUNX2 mRNA CTD PMID:24915843 neoeriocitrin increases expression ISO RGD:735753 6480464 neoeriocitrin results in increased expression of RUNX2 mRNA CTD PMID:21741227 niclosamide decreases expression ISO RGD:735753 6480464 Niclosamide results in decreased expression of RUNX2 mRNA CTD PMID:28824321 nicotinamide decreases expression ISO RGD:735753 6480464 Niacinamide results in decreased expression of RUNX2 mRNA, Niacinamide results in decreased expression of RUNX2 protein CTD PMID:16813520 , PMID:22539994 nicotinamide multiple interactions ISO RGD:735753 6480464 resveratrol inhibits the reaction [Niacinamide results in decreased expression of RUNX2 protein] CTD PMID:22539994 nicotinamide increases expression EXP 6480464 Niacinamide results in increased expression of RUNX2 mRNA CTD PMID:16813520 notoginsenoside R1 multiple interactions ISO RGD:1348975 6480464 fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of RUNX2 mRNA] CTD PMID:26362186 notoginsenoside R1 increases expression ISO RGD:1348975 6480464 notoginsenoside R1 results in increased expression of RUNX2 mRNA CTD PMID:26362186 NS-398 multiple interactions ISO RGD:735753 6480464 [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 mRNA, [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 protein CTD PMID:27050768 ochratoxin A decreases expression ISO RGD:1348975 6480464 ochratoxin A results in decreased expression of RUNX2 mRNA CTD PMID:30559759 panobinostat multiple interactions ISO RGD:1348975 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA CTD PMID:27188386 paracetamol increases expression ISO RGD:1348975 6480464 Acetaminophen results in increased expression of RUNX2 mRNA CTD PMID:29067470 PCB138 multiple interactions ISO RGD:735753 6480464 [2 more ... CTD PMID:25510870 PCB138 increases expression EXP 6480464 2 more ... CTD PMID:23829299 perfluorononanoic acid decreases expression ISO RGD:1348975 6480464 perfluorononanoic acid results in decreased expression of RUNX2 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1348975 6480464 perfluorooctane sulfonic acid results in decreased expression of RUNX2 mRNA CTD PMID:32588087 phenethyl caffeate multiple interactions EXP 6480464 caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 protein] CTD PMID:28363435 phenylmercury acetate increases expression ISO RGD:1348975 6480464 Phenylmercuric Acetate results in increased expression of RUNX2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1348975 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA CTD PMID:27188386 phylloquinone multiple interactions EXP 6480464 [Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 mRNA more ... CTD PMID:27412937 picene increases expression ISO RGD:1348975 6480464 picene results in increased expression of RUNX2 mRNA CTD PMID:32251684 polaprezinc increases expression ISO RGD:735753 6480464 polaprezinc results in increased expression of RUNX2 mRNA CTD PMID:18327666 potassium chromate multiple interactions ISO RGD:1348975 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of RUNX2 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:1348975 6480464 potassium chromate(VI) results in decreased expression of RUNX2 mRNA CTD PMID:22079256 progesterone multiple interactions ISO RGD:1348975 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of RUNX2 mRNA CTD PMID:20660070 prostaglandin E2 increases expression ISO RGD:735753 6480464 Dinoprostone results in increased expression of RUNX2 mRNA, Dinoprostone results in increased expression of RUNX2 protein CTD PMID:27050768 prostaglandin F2alpha increases expression ISO RGD:735753 6480464 Dinoprost results in increased expression of RUNX2 mRNA, Dinoprost results in increased expression of RUNX2 protein CTD PMID:27050768 quercetin increases expression EXP 6480464 Quercetin results in increased expression of RUNX2 mRNA CTD PMID:17243115 more ... quercetin multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA] more ... CTD PMID:23117658 more ... quercetin increases expression ISO RGD:1348975 6480464 Quercetin results in increased expression of RUNX2 mRNA CTD PMID:16996034 quercetin 3-O-beta-D-glucofuranoside increases expression EXP 6480464 isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 quercetin 3-O-beta-D-glucopyranoside increases expression EXP 6480464 isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 raloxifene affects expression ISO RGD:735753 6480464 Raloxifene Hydrochloride affects the expression of RUNX2 mRNA CTD PMID:17166402 resveratrol multiple interactions ISO RGD:1348975 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased expression of RUNX2 mRNA] more ... CTD PMID:17689939 , PMID:21713995 resveratrol increases expression ISO RGD:735753 6480464 resveratrol results in increased expression of RUNX2 mRNA CTD PMID:19665018 resveratrol multiple interactions ISO RGD:735753 6480464 resveratrol inhibits the reaction [Niacinamide results in decreased expression of RUNX2 protein] CTD PMID:22539994 resveratrol increases expression ISO RGD:1348975 6480464 resveratrol results in increased expression of RUNX2 mRNA CTD PMID:17689939 more ... resveratrol increases expression EXP 6480464 resveratrol results in increased expression of RUNX2 mRNA CTD PMID:16813520 riboflavin increases expression ISO RGD:735753 6480464 Riboflavin analog results in increased expression of RUNX2 protein CTD PMID:20688149 rotenone decreases expression ISO RGD:1348975 6480464 Rotenone results in decreased expression of RUNX2 mRNA CTD PMID:29331484 rottlerin multiple interactions ISO RGD:735753 6480464 rottlerin inhibits the reaction [FGF2 protein results in increased activity of RUNX2 protein], rottlerin inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA] CTD PMID:12403780 S-(1,2-dichlorovinyl)-L-cysteine decreases expression ISO RGD:1348975 6480464 S-(1, 2-dichlorovinyl)cysteine results in decreased expression of RUNX2 mRNA CTD PMID:33725128 Salidroside increases expression ISO RGD:735753 6480464 rhodioloside results in increased expression of RUNX2 mRNA CTD PMID:24055767 Salidroside increases activity ISO RGD:735753 6480464 rhodioloside results in increased activity of RUNX2 protein CTD PMID:24055767 SB 203580 multiple interactions EXP 6480464 [pyrazolanthrone co-treated with SB 203580 co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA], SB 203580 inhibits the reaction [cobaltous chloride results in increased expression of RUNX2 mRNA] CTD PMID:26136938 , PMID:31472278 SB 431542 multiple interactions ISO RGD:1348975 6480464 4-(5-benzo(1 more ... CTD PMID:20458730 , PMID:27188386 sclareol increases expression ISO RGD:735753 6480464 sclareol results in increased expression of RUNX2 mRNA, sclareol results in increased expression of RUNX2 protein CTD PMID:33423118 silicon dioxide increases expression ISO RGD:1348975 6480464 Silicon Dioxide analog results in increased expression of RUNX2 mRNA CTD PMID:25895662 simvastatin increases expression ISO RGD:1348975 6480464 Simvastatin results in increased expression of RUNX2 CTD PMID:20381859 simvastatin increases expression ISO RGD:735753 6480464 Simvastatin results in increased expression of RUNX2 mRNA CTD PMID:20417880 , PMID:22058016 simvastatin multiple interactions ISO RGD:735753 6480464 DKK1 inhibits the reaction [Simvastatin results in increased expression of RUNX2 mRNA] more ... CTD PMID:18310456 , PMID:22058016 sirolimus multiple interactions ISO RGD:1348975 6480464 Sirolimus inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:23111315 sodium arsenite decreases expression ISO RGD:735753 6480464 sodium arsenite results in decreased expression of RUNX2 mRNA CTD PMID:28206643 sodium arsenite increases expression ISO RGD:1348975 6480464 sodium arsenite results in increased expression of RUNX2 mRNA CTD PMID:29301061 sodium fluoride affects expression EXP 6480464 Sodium Fluoride affects the expression of RUNX2 mRNA CTD PMID:25132241 sodium fluoride decreases expression ISO RGD:1348975 6480464 Sodium Fluoride results in decreased expression of RUNX2 mRNA CTD PMID:26339601 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of RUNX2 mRNA, Sodium Fluoride results in increased expression of RUNX2 protein CTD PMID:24300170 sodium fluoride multiple interactions EXP 6480464 DKK1 protein inhibits the reaction [Sodium Fluoride results in increased expression of RUNX2 mRNA], DKK1 protein inhibits the reaction [Sodium Fluoride results in increased expression of RUNX2 protein] CTD PMID:24300170 sodium fluoride multiple interactions ISO RGD:735753 6480464 [Sodium Fluoride co-treated with aluminum chloride] results in increased expression of RUNX2 mRNA CTD PMID:21560300 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of RUNX2 mRNA CTD PMID:25617479 succimer multiple interactions ISO RGD:735753 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of RUNX2 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of RUNX2 mRNA CTD PMID:21641980 , PMID:26378955 tacrolimus hydrate decreases expression EXP 6480464 Tacrolimus results in decreased expression of RUNX2 mRNA CTD PMID:15780950 tamibarotene decreases expression ISO RGD:1348975 6480464 tamibarotene results in decreased expression of RUNX2 mRNA CTD PMID:15498508 Tanshinone I multiple interactions ISO RGD:735753 6480464 MIR322 mRNA inhibits the reaction [tanshinone results in increased expression of RUNX2 protein], pyrazolanthrone inhibits the reaction [tanshinone results in increased expression of RUNX2 protein] CTD PMID:31306638 Tanshinone I increases expression ISO RGD:735753 6480464 tanshinone results in increased expression of RUNX2 protein CTD PMID:31306638 tebuconazole decreases expression ISO RGD:1348975 6480464 tebuconazole results in decreased expression of RUNX2 mRNA CTD PMID:30458266 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of RUNX2 mRNA CTD PMID:17334410 tetrachloromethane multiple interactions EXP 6480464 FR 167653 inhibits the reaction [Carbon Tetrachloride results in increased expression of RUNX2 mRNA] CTD PMID:17334410 tetrachloromethane affects expression ISO RGD:735753 6480464 Carbon Tetrachloride affects the expression of RUNX2 mRNA CTD PMID:17484886 thromboxane A2 increases expression ISO RGD:735753 6480464 Thromboxane A2 results in increased expression of RUNX2 mRNA, Thromboxane A2 results in increased expression of RUNX2 protein CTD PMID:27050768 tremolite asbestos increases expression ISO RGD:735753 6480464 tremolite results in increased expression of RUNX2 mRNA CTD PMID:29279043 tributyl phosphate multiple interactions ISO RGD:735753 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1, 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in decreased expression of RUNX2 mRNA CTD PMID:33367866 tributylstannane decreases expression ISO RGD:735753 6480464 tributyltin results in decreased expression of RUNX2 mRNA CTD PMID:23322813 more ... trichostatin A increases expression ISO RGD:1348975 6480464 trichostatin A results in increased expression of RUNX2 mRNA CTD PMID:24935251 triclosan increases expression ISO RGD:1348975 6480464 Triclosan results in increased expression of RUNX2 mRNA CTD PMID:30510588 triflumizole decreases expression ISO RGD:735753 6480464 triflumizol results in decreased expression of RUNX2 mRNA CTD PMID:23086663 trimellitic anhydride increases expression ISO RGD:735753 6480464 trimellitic anhydride results in increased expression of RUNX2 mRNA CTD PMID:19042947 triphenyl phosphate decreases expression ISO RGD:735753 6480464 triphenyl phosphate results in decreased expression of RUNX2 mRNA CTD PMID:30561715 triphenyl phosphate multiple interactions ISO RGD:735753 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1, 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in decreased expression of RUNX2 mRNA CTD PMID:33367866 tris(2-butoxyethyl) phosphate multiple interactions ISO RGD:735753 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1, 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in decreased expression of RUNX2 mRNA CTD PMID:33367866 tris(2-chloroethyl) phosphate multiple interactions ISO RGD:735753 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1, 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in decreased expression of RUNX2 mRNA CTD PMID:33367866 troglitazone decreases expression ISO RGD:735753 6480464 troglitazone results in decreased expression of RUNX2 mRNA CTD PMID:16813520 , PMID:19122273 tungsten decreases expression ISO RGD:735753 6480464 Tungsten results in decreased expression of RUNX2 mRNA CTD PMID:26865663 tyrphostin AG 1478 decreases expression EXP 6480464 RTKI cpd results in decreased expression of RUNX2 mRNA CTD PMID:20197312 valproic acid decreases expression ISO RGD:735753 6480464 Valproic Acid results in decreased expression of RUNX2 mRNA CTD PMID:23042728 valproic acid multiple interactions ISO RGD:1348975 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 , PMID:32623605 valproic acid increases expression ISO RGD:1348975 6480464 Valproic Acid results in increased expression of RUNX2 mRNA CTD PMID:23179753 more ... valproic acid decreases methylation ISO RGD:1348975 6480464 Valproic Acid results in decreased methylation of RUNX2 gene CTD PMID:29154799 vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of RUNX2 gene CTD PMID:31079544 vitamin K multiple interactions EXP 6480464 [Warfarin co-treated with Vitamin K] results in increased expression of RUNX2 mRNA, Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of RUNX2 mRNA] CTD PMID:23117658 warfarin multiple interactions ISO RGD:735753 6480464 Warfarin inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein] more ... CTD PMID:21910061 warfarin multiple interactions EXP 6480464 [Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 mRNA more ... CTD PMID:23117658 , PMID:27412937 zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of RUNX2 mRNA, Zinc deficiency results in decreased expression of RUNX2 protein CTD PMID:21893222 zinc dichloride multiple interactions ISO RGD:735753 6480464 [zinc chloride co-treated with N more ... CTD PMID:19913120 zinc sulfate multiple interactions ISO RGD:735753 6480464 Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA], Dichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA] CTD PMID:18327666 zinc sulfate increases expression ISO RGD:735753 6480464 Zinc Sulfate results in increased expression of RUNX2 mRNA CTD PMID:18327666 zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of RUNX2 mRNA, Zinc deficiency results in decreased expression of RUNX2 protein CTD PMID:21893222 zoledronic acid increases expression ISO RGD:1348975 6480464 zoledronic acid results in increased expression of RUNX2 mRNA CTD PMID:25596134
