GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Runx2 | decreases expression | EXP | | 6480464 | CTD | Glucose results in decreased expression of RUNX2 mRNA; Glucose results in decreased expression of RUNX2 protein | PMID:32643284 | Runx2 | multiple interactions | EXP | | 6480464 | CTD | morroniside inhibits the reaction [Glucose results in decreased expression of RUNX2 mRNA]; morroniside inhibits the reaction [Glucose results in decreased expression of RUNX2 protein] | PMID:32643284 | Runx2 | decreases expression | ISO | RUNX2 (Homo sapiens) | 6480464 | CTD | Glucose results in decreased expression of RUNX2 mRNA; Glucose results in decreased expression of RUNX2 protein | PMID:38000455 | Runx2 | decreases expression | ISO | Runx2 (Mus musculus) | 6480464 | CTD | Glucose results in decreased expression of RUNX2 mRNA; Glucose results in decreased expression of RUNX2 protein | PMID:33450223 | Runx2 | increases expression | ISO | Runx2 (Mus musculus) | 6480464 | CTD | Glucose results in increased expression of RUNX2 mRNA | PMID:17178593 | Runx2 | multiple interactions | ISO | RUNX2 (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytic Acid inhibits the reaction [Glucose results in decreased expression of RUNX2 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytic Acid inhibits the reaction [Glucose results in decreased expression of RUNX2 protein]]; [EPO protein co-treated with Glucose] results in increased expression of RUNX2 mRNA; [EPO protein co-treated with Glucose] results in increased expression of RUNX2 protein; Melatonin inhibits the reaction [Glucose results in decreased expression of RUNX2 mRNA]; Melatonin inhibits the reaction [Glucose results in decreased expression of RUNX2 protein]; Phytic Acid inhibits the reaction [Glucose results in decreased expression of RUNX2 mRNA]; Phytic Acid inhibits the reaction [Glucose results in decreased expression of RUNX2 protein] | PMID:30894315 PMID:38000455 | Runx2 | multiple interactions | ISO | Runx2 (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of RUNX2 protein]]; Calcitriol inhibits the reaction [Glucose results in decreased expression of RUNX2 mRNA]; Calcitriol inhibits the reaction [Glucose results in decreased expression of RUNX2 protein]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of RUNX2 mRNA]]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of RUNX2 protein]]; Sirolimus inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of RUNX2 mRNA]]; Sirolimus inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of RUNX2 protein]] | PMID:33450223 | |
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