Gene: Hdac8 (histone deacetylase 8) Rattus norvegicus
Symbol: Hdac8
Name: histone deacetylase 8
Description: ENCODES a protein that exhibits chromatin binding; deacetylase activity; transcription factor binding; INVOLVED IN cellular response to forskolin; cellular response to trichostatin A; negative regulation of gene expression; ASSOCIATED WITH amphetamine abuse; Cardiomegaly; hypertension; FOUND IN nucleus; plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,2',5,5'-tetrachlorobiphenyl; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HD8; LOC363481; RGD1562895; similar to Histone deacetylase 8 (HD8)
Homo sapiens (human) : HDAC8 (histone deacetylase 8)  HGNC  Alliance
Mus musculus (house mouse) : Hdac8 (histone deacetylase 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac8 (histone deacetylase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC8 (histone deacetylase 8)
Canis lupus familiaris (dog) : HDAC8 (histone deacetylase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac8 (histone deacetylase 8)
Sus scrofa (pig) : HDAC8 (histone deacetylase 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X72,163,777 - 72,370,058 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X73,566,613 - 73,589,000 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X73,694,610 - 73,698,948 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X90,336,001 - 90,544,511 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX67,738,891 - 67,946,303 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Hdac8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562895
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE