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Gene: Hdac4 (histone deacetylase 4) Rattus norvegicus
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Symbol: Hdac4
Name: histone deacetylase 4
Description: Exhibits promoter-specific chromatin binding activity and transcription factor binding activity. Predicted to contribute to sequence-specific DNA binding activity and transcription regulatory region DNA binding activity. Involved in several processes, including cellular response to mechanical stimulus; cellular response to parathyroid hormone stimulus; and positive regulation of lamellipodium assembly. Localizes to the cytoplasm; nucleus; and protein-containing complex. Biomarker of middle cerebral artery infarction. Human ortholog(s) of this gene implicated in ataxia telangiectasia; eating disorder; and retinal degeneration. Orthologous to human HDAC4 (histone deacetylase 4); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; histone modification pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: HD4; LOC363287
Orthologs:
Homo sapiens (human) : HDAC4 (histone deacetylase 4)  HGNC  Alliance
Mus musculus (house mouse) : Hdac4 (histone deacetylase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac4 (histone deacetylase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC4 (histone deacetylase 4)
Canis lupus familiaris (dog) : HDAC4 (histone deacetylase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac4 (histone deacetylase 4)
Sus scrofa (pig) : HDAC4 (histone deacetylase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0999,052,945 - 99,299,715 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0998,727,262 - 98,973,829 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4991,147,435 - 91,389,810 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1991,421,635 - 91,447,796 (+)NCBI
Celera990,047,090 - 90,289,214 (-)NCBICelera
Cytogenetic Map9q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

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References - curated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
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Sequence

Nucleotide Sequences
Protein Sequences
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Strain Variation

Strain Sequence Variants (Rnor 5.0)
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Additional Information

External Database Links
Nomenclature History
  
More on Hdac4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619979
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-27
Status: ACTIVE



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