GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Runx2 | decreases expression | ISO | Runx2 (Mus musculus) | 6480464 | CTD | Valproic Acid results in decreased expression of RUNX2 mRNA | PMID:23042728 | Runx2 | decreases methylation | ISO | RUNX2 (Homo sapiens) | 6480464 | CTD | Valproic Acid results in decreased methylation of RUNX2 gene | PMID:29154799 | Runx2 | increases expression | ISO | RUNX2 (Homo sapiens) | 6480464 | CTD | Valproic Acid results in increased expression of RUNX2 mRNA | PMID:23179753 PMID:24383497 PMID:24935251 PMID:26272509 PMID:28001369 PMID:32623605 | Runx2 | multiple interactions | ISO | RUNX2 (Homo sapiens) | 6480464 | CTD | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA; CEBPA protein affects the reaction [Valproic Acid results in increased expression of RUNX2 mRNA] | PMID:27188386 PMID:32623605 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |