Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Notes | Source | Original Reference(s) | ACE2 | Human | telmisartan | decreases expression | ISO | Ace2 (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of rats with periodontal disease | RGD | | ACP5 | Human | telmisartan | decreases activity | ISO | Acp5 (Rattus norvegicus) | telmisartan decreases enzyme activity of Trap and Acp5 in serum of rats with periodontal disease | RGD | | AGTR1 | Human | telmisartan | decreases expression | ISO | Agtr1a (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of rats with periodontal disease | RGD | | AGTR2 | Human | telmisartan | increases expression | ISO | Agtr2 (Rattus norvegicus) | telmisartan increases expression of mRNA in mandible of rats with periodontal disease | RGD | | ALPL | Human | telmisartan | increases activity | ISO | Alpl (Rattus norvegicus) | telmisartan increases enzyme activity of Alpl in serum of rats with periodontal disease | RGD | | Ace2 | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of mRNA in mandible of rats with periodontal disease | RGD | | Ace2 | Mouse | telmisartan | decreases expression | ISO | Ace2 (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of rats with periodontal disease | RGD | | Acp5 | Rat | telmisartan | decreases activity | EXP | | telmisartan decreases enzyme activity of Trap and Acp5 in serum of rats with periodontal disease | RGD | | Acp5 | Mouse | telmisartan | decreases activity | ISO | Acp5 (Rattus norvegicus) | telmisartan decreases enzyme activity of Trap and Acp5 in serum of rats with periodontal disease | RGD | | Agtr1a | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of mRNA in mandible of rats with periodontal disease | RGD | | Agtr1a | Mouse | telmisartan | decreases expression | ISO | Agtr1a (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of rats with periodontal disease | RGD | | Agtr2 | Rat | telmisartan | increases expression | EXP | | telmisartan increases expression of mRNA in mandible of rats with periodontal disease | RGD | | Agtr2 | Mouse | telmisartan | increases expression | ISO | Agtr2 (Rattus norvegicus) | telmisartan increases expression of mRNA in mandible of rats with periodontal disease | RGD | | Alpl | Rat | telmisartan | increases activity | EXP | | telmisartan increases enzyme activity of Alpl in serum of rats with periodontal disease | RGD | | Alpl | Mouse | telmisartan | increases activity | ISO | Alpl (Rattus norvegicus) | telmisartan increases enzyme activity of Alpl in serum of rats with periodontal disease | RGD | | CTSK | Human | telmisartan | decreases expression | ISO | Ctsk (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of rats with periodontal disease | RGD | | CXCL1 | Human | telmisartan | decreases expression | ISO | Cxcl3 (Rattus norvegicus) | telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease | RGD | | Ctsk | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of mRNA in mandible of rats with periodontal disease | RGD | | Ctsk | Mouse | telmisartan | decreases expression | ISO | Ctsk (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of rats with periodontal disease | RGD | | Cxcl3 | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease | RGD | | Cxcl3 | Mouse | telmisartan | decreases expression | ISO | Cxcl3 (Rattus norvegicus) | telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease | RGD | | IBSP | Human | telmisartan | increases expression | ISO | Ibsp (Rattus norvegicus) | telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | IL10 | Human | telmisartan | decreases expression | ISO | Il10 (Rattus norvegicus) | telmisartan decreases expression of protein in mandible of WKY rats with periodontal disease | RGD | | IL1B | Human | telmisartan | decreases expression | ISO | Il1b (Rattus norvegicus) | telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease | RGD | | Ibsp | Rat | telmisartan | increases expression | EXP | | telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | Ibsp | Mouse | telmisartan | increases expression | ISO | Ibsp (Rattus norvegicus) | telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | Il10 | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of protein in mandible of WKY rats with periodontal disease | RGD | | Il10 | Mouse | telmisartan | decreases expression | ISO | Il10 (Rattus norvegicus) | telmisartan decreases expression of protein in mandible of WKY rats with periodontal disease | RGD | | Il1b | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease | RGD | | Il1b | Mouse | telmisartan | decreases expression | ISO | Il1b (Rattus norvegicus) | telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease | RGD | | MMP2 | Human | telmisartan | decreases expression | ISO | Mmp2 (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | MMP9 | Human | telmisartan | decreases expression | ISO | Mmp9 (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease | RGD | | Mmp2 | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | Mmp2 | Mouse | telmisartan | decreases expression | ISO | Mmp2 (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | Mmp9 | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease | RGD | | Mmp9 | Mouse | telmisartan | decreases expression | ISO | Mmp9 (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease | RGD | | RUNX2 | Human | telmisartan | increases expression | ISO | Runx2 (Rattus norvegicus) | telmisartan increases expression of mRNA in mandible of rats with periodontal disease | RGD | | Runx2 | Rat | telmisartan | increases expression | EXP | | telmisartan increases expression of mRNA in mandible of rats with periodontal disease | RGD | | Runx2 | Mouse | telmisartan | increases expression | ISO | Runx2 (Rattus norvegicus) | telmisartan increases expression of mRNA in mandible of rats with periodontal disease | RGD | | SPP1 | Human | telmisartan | increases expression | ISO | Spp1 (Rattus norvegicus) | telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | Spp1 | Rat | telmisartan | increases expression | EXP | | telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | Spp1 | Mouse | telmisartan | increases expression | ISO | Spp1 (Rattus norvegicus) | telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | TNF | Human | telmisartan | decreases expression | ISO | Tnf (Rattus norvegicus) | telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease | RGD | | TNFRSF11B | Human | telmisartan | increases expression | ISO | Tnfrsf11b (Rattus norvegicus) | telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | TNFSF11 | Human | telmisartan | decreases expression | ISO | Tnfsf11 (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease | RGD | | Tnf | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease | RGD | | Tnf | Mouse | telmisartan | decreases expression | ISO | Tnf (Rattus norvegicus) | telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease | RGD | | Tnfrsf11b | Mouse | telmisartan | increases expression | ISO | Tnfrsf11b (Rattus norvegicus) | telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | Tnfrsf11b | Rat | telmisartan | increases expression | EXP | | telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease | RGD | | Tnfsf11 | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease | RGD | | Tnfsf11 | Mouse | telmisartan | decreases expression | ISO | Tnfsf11 (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease | RGD | | VTN | Human | telmisartan | decreases expression | ISO | Vtn (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease | RGD | | Vtn | Rat | telmisartan | decreases expression | EXP | | telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease | RGD | | Vtn | Mouse | telmisartan | decreases expression | ISO | Vtn (Rattus norvegicus) | telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease | RGD | | |