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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Cnnm4 | Rat | Amaurosis Hypertrichosis | | ISO | CNNM4 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Cnnm4 | Rat | Amaurosis Hypertrichosis | | ISO | CNNM4 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Physical interaction and functional coupling between ACDP4 and the intracellular ion chaperone COX11, an implication of the role of ACDP4 in essential metal ion transport and homeostasis. | Guo D, etal., Mol Pain. 2005 Apr 19;1:15. |
3. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
4. | GOA pipeline | RGD automated data pipeline |
5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Cnnm4 (Rattus norvegicus - Norway rat) |
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CNNM4 (Homo sapiens - human) |
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Cnnm4 (Mus musculus - house mouse) |
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Cnnm4 (Chinchilla lanigera - long-tailed chinchilla) |
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CNNM4 (Pan paniscus - bonobo/pygmy chimpanzee) |
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CNNM4 (Canis lupus familiaris - dog) |
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Cnnm4 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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CNNM4 (Sus scrofa - pig) |
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CNNM4 (Chlorocebus sabaeus - green monkey) |
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Cnnm4 (Heterocephalus glaber - naked mole-rat) |
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Variants in Cnnm4
132 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
AA859983 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
RefSeq Transcripts | NM_001271050 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006244827 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017596510 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039083840 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH473965 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
JAXUCZ010000009 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000021434 ⟹ ENSRNOP00000021434 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000079234 ⟹ ENSRNOP00000070598 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_001271050 ⟹ NP_001257979 | ||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006244827 ⟹ XP_006244889 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017596510 ⟹ XP_017451999 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039083840 ⟹ XP_038939768 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Protein RefSeqs | NP_001257979 | (Get FASTA) | NCBI Sequence Viewer |
XP_006244889 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017451999 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038939768 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | EDL99274 | (Get FASTA) | NCBI Sequence Viewer |
Ensembl Protein | ENSRNOP00000021434.4 | ||
ENSRNOP00000070598.2 | |||
GenBank Protein | P0C588 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001257979 ⟸ NM_001271050 |
- Peptide Label: | precursor |
- UniProtKB: | P0C588 (UniProtKB/Swiss-Prot), A6IND6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006244889 ⟸ XM_006244827 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A6IND6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017451999 ⟸ XM_017596510 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A0G2JYC2 (UniProtKB/TrEMBL), A6IND6 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000070598 ⟸ ENSRNOT00000079234 |
Ensembl Acc Id: | ENSRNOP00000021434 ⟸ ENSRNOT00000021434 |
RefSeq Acc Id: | XP_038939768 ⟸ XM_039083840 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A6IND6 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-P0C588-F1-model_v2 | AlphaFold | P0C588 | 1-772 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13696602 | ||||||||
Promoter ID: | EPDNEW_R7127 | ||||||||
Type: | single initiation site | ||||||||
Name: | Cnnm4_1 | ||||||||
Description: | cyclin and CBS domain divalent metal cation transport mediator4 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1305571 | AgrOrtholog |
BioCyc Gene | G2FUF-27810 | BioCyc |
Ensembl Genes | ENSRNOG00000015886 | Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000021434.8 | UniProtKB/Swiss-Prot |
ENSRNOT00000079234.2 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.60.120.10 | UniProtKB/Swiss-Prot |
3.10.580.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Jelly Rolls | UniProtKB/TrEMBL | |
InterPro | ACDP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
CBS_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
CBS_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
cNMP-bd-like | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
CNNM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Ion_transp-like_CBS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RmlC-like_jellyroll | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:363216 | UniProtKB/Swiss-Prot |
NCBI Gene | 363216 | ENTREZGENE |
PANTHER | METAL TRANSPORTER CNNM4 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PTHR12064 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | CBS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
DUF21 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Cnnm4 | PhenoGen |
PROSITE | CBS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
CNNM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000015886 | RatGTEx |
Superfamily-SCOP | SSF51206 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SSF54631 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UniProt | A0A0G2JYC2 | ENTREZGENE, UniProtKB/TrEMBL |
A6IND6 | ENTREZGENE, UniProtKB/TrEMBL | |
CNNM4_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2014-08-13 | Cnnm4 | cyclin and CBS domain divalent metal cation transport mediator 4 | Cnnm4 | cyclin M4 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-04-30 | Cnnm4 | cyclin M4 | Cnnm4_predicted | cyclin M4 (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2005-01-12 | Cnnm4_predicted | cyclin M4 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |