Il1r1 (interleukin 1 receptor type 1) - Rat Genome Database
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Gene: Il1r1 (interleukin 1 receptor type 1) Rattus norvegicus
Analyze
Symbol: Il1r1
Name: interleukin 1 receptor type 1
RGD ID: 2892
Description: Exhibits ionotropic glutamate receptor binding activity. Involved in several processes, including interleukin-1-mediated signaling pathway; positive regulation of neuron migration; and response to odorant. Localizes to several cellular components, including axon; cell surface; and postsynaptic density. Biomarker of pulpitis. Human ortholog(s) of this gene implicated in systemic scleroderma and type 1 diabetes mellitus. Orthologous to human IL1R1 (interleukin 1 receptor type 1); PARTICIPATES IN interleukin-1 signaling pathway; interleukin-12 signaling pathway; apoptotic cell death pathway; INTERACTS WITH (S)-nicotine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD121 antigen-like family member A; IL-1R-1; IL-1R-alpha; IL-1RT-1; IL-1RT1; interleukin 1 beta receptor type 1 short transmembrane form; interleukin 1 beta receptor type 1 soluble form; interleukin 1 bete receptor type 1 long transmembrane form; interleukin 1 receptor, type I; interleukin-1 receptor alpha; interleukin-1 receptor type 1; interleukin-1 receptor type I; p80
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Il1r1em3Mcwi   Il1r1em2Mcwi   Il1r1em1Mcwi  
Genetic Models: BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em1Mcwi BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2942,504,917 - 42,580,958 (+)NCBI
Rnor_6.0 Ensembl946,962,288 - 47,036,670 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0946,962,291 - 47,038,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0946,647,422 - 46,723,241 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4939,434,910 - 39,473,552 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1939,434,750 - 39,475,060 (+)NCBI
Celera940,285,956 - 40,323,730 (+)NCBICelera
RH 3.4 Map9396.1RGD
Cytogenetic Map9q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
(S)-nicotine  (EXP)
1,10-phenanthroline  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-hydroxycyclophosphamide  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
adenosine  (EXP)
afimoxifene  (EXP)
aflatoxin B1  (ISO)
AH23848  (ISO)
albendazole  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
aluminium hydroxide  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
asperentin  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
captan  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
carrageenan  (ISO)
chloroethene  (ISO)
chromium(6+)  (ISO)
chrysin  (ISO)
ciglitazone  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDT  (EXP)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
edaravone  (EXP)
ellagic acid  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
erlotinib hydrochloride  (ISO)
fenvalerate  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
folpet  (ISO)
fonofos  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP)
leflunomide  (EXP)
lenalidomide  (ISO)
lipopolysaccharide  (EXP,ISO)
magnesium dihydroxide  (ISO)
manganese(II) chloride  (EXP)
methimazole  (EXP)
methoxychlor  (EXP)
methyllycaconitine  (EXP)
mycophenolic acid  (ISO)
mycotoxin  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (ISO)
neoechinulin A  (ISO)
nickel sulfate  (ISO)
nicotine  (EXP)
o-anisidine  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP,ISO)
prostaglandin E2  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
Soman  (ISO)
sterigmatocystin  (ISO)
sulfasalazine  (EXP)
sulforaphane  (ISO)
sulindac sulfide  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thalidomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (ISO)
triadimefon  (EXP)
tributylstannane  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimethyltin  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
1. Aveleira C, etal., Cytokine. 2010 Mar;49(3):279-86. doi: 10.1016/j.cyto.2009.11.014. Epub 2010 Jan 19.
2. Bergholdt R, etal., Genes Immun. 2000 Dec;1(8):495-500.
3. Blanco-Melo D, etal., Cell. 2020 May 28;181(5):1036-1045.e9. doi: 10.1016/j.cell.2020.04.026. Epub 2020 May 15.
4. Bletsa A, etal., Int Endod J. 2009 Nov;42(11):978-86. doi: 10.1111/j.1365-2591.2009.01605.x. Epub 2009 Sep 1.
5. Bujia J, etal., Eur Arch Otorhinolaryngol. 1996;253(4-5):252-5.
6. Ciarrocchi A, etal., PLoS One. 2009;4(2):e4404. Epub 2009 Feb 9.
7. Fernandes A, etal., Glia. 2011 Jan;59(1):14-25. doi: 10.1002/glia.21072. Epub 2010 Oct 21.
8. Frank JA, etal., Thorax. 2008 Feb;63(2):147-53. Epub 2007 Sep 27.
9. Gardoni F, etal., J Neuroinflammation. 2011 Feb 11;8(1):14.
10. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
11. Gentil K and Pearlman E, Infect Immun. 2009 Apr;77(4):1606-12. doi: 10.1128/IAI.00671-08. Epub 2009 Jan 21.
12. GOA data from the GO Consortium
13. Hart RP, etal., J Neuroimmunol 1993 Apr;44(1):49-56.
14. Huang C, etal., Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
15. Irwin LN and Byers DM, Brain Res. 2012 Dec 13;1489:1-7. doi: 10.1016/j.brainres.2012.10.034. Epub 2012 Oct 26.
16. Jafarian-Tehrani M, etal., Endocrinology. 1995 Feb;136(2):609-13.
17. Kawaguchi Y, etal., Biochem Biophys Res Commun. 1992 May 15;184(3):1504-10.
18. Kol S, etal., Mol Cell Endocrinol. 1999 Mar 25;149(1-2):115-28.
19. Kong SL, etal., Virus Res. 2009 Nov;145(2):260-9. Epub 2009 Jul 25.
20. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
21. Ma L, etal., J Neuroinflammation. 2014 Jun 21;11:114. doi: 10.1186/1742-2094-11-114.
22. Metcalfe KA, etal., Hum Immunol. 1996 Nov;51(1):41-8.
23. MGD data from the GO Consortium
24. NCBI rat LocusLink and RefSeq merged data July 26, 2002
25. Pipeline to import KEGG annotations from KEGG into RGD
26. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
27. RGD automated data pipeline
28. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
29. RGD automated import pipeline for gene-chemical interactions
30. RGD comprehensive gene curation
31. Sasaki M, etal., Brain Res Mol Brain Res. 2001 Apr 18;89(1-2):158-63.
32. Schafers M, etal., Neurosci Lett. 2001 Sep 14;310(2-3):113-6.
33. Shiue HS, etal., J Altern Complement Med. 2008 Jul;14(6):689-98.
34. Sims JE and Smith DE, Nat Rev Immunol. 2010 Feb;10(2):89-102. Epub 2010 Jan 18.
35. Song MJ, etal., Brain Res Bull. 2009 Mar 30;78(6):335-41. doi: 10.1016/j.brainresbull.2008.10.009. Epub 2008 Nov 18.
36. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
37. Wang XF, etal., Acta Neuropathol. 2006 Mar;111(3):220-8. Epub 2006 Feb 3.
38. Wieland CW, etal., Microbes Infect. 2006 Aug;8(9-10):2409-13. Epub 2006 Jun 2.
39. Wise GE and Zhao L, Arch Oral Biol. 1997 May;42(5):339-44.
40. Xie C, etal., Clin Immunol. 2007 Jul;124(1):49-56. Epub 2007 May 17.
41. Yamada M, etal., Nitric Oxide. 2007 Sep;17(2):98-105. Epub 2007 Jul 1.
42. Yang Y, etal., J Allergy Clin Immunol. 2020 Apr 29. pii: S0091-6749(20)30576-5. doi: 10.1016/j.jaci.2020.04.027.
43. Zhang Y, etal., J Ethnopharmacol. 2012 Jun 1;141(2):599-602. doi: 10.1016/j.jep.2011.09.001. Epub 2011 Sep 8.
44. Zhou R, etal., Invest Ophthalmol Vis Sci. 2012 Oct 25;53(11):7382-8. doi: 10.1167/iovs.12-10238.
Additional References at PubMed
PMID:10383454   PMID:10653850   PMID:10854325   PMID:11880380   PMID:12135759   PMID:12627233   PMID:15024756   PMID:15030977   PMID:15292196   PMID:16477012   PMID:16757809   PMID:18996842  
PMID:19833765   PMID:22297845   PMID:23034280   PMID:23395675   PMID:23992404   PMID:26902320   PMID:27440742   PMID:28645297  


Genomics

Comparative Map Data
Il1r1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2942,504,917 - 42,580,958 (+)NCBI
Rnor_6.0 Ensembl946,962,288 - 47,036,670 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0946,962,291 - 47,038,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0946,647,422 - 46,723,241 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4939,434,910 - 39,473,552 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1939,434,750 - 39,475,060 (+)NCBI
Celera940,285,956 - 40,323,730 (+)NCBICelera
RH 3.4 Map9396.1RGD
Cytogenetic Map9q22NCBI
IL1R1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2102,064,544 - 102,179,874 (+)EnsemblGRCh38hg38GRCh38
GRCh382102,069,638 - 102,179,874 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372102,686,836 - 102,796,334 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh372102,686,850 - 102,796,334 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362102,136,834 - 102,162,766 (+)NCBINCBI36hg18NCBI36
Build 342102,228,919 - 102,254,852NCBI
Celera296,971,617 - 96,997,550 (+)NCBI
Cytogenetic Map2q11.2-q12.1NCBI
HuRef296,534,264 - 96,560,197 (+)NCBIHuRef
CHM1_12102,691,224 - 102,800,675 (+)NCBICHM1_1
Il1r1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39140,261,651 - 40,355,361 (+)NCBIGRCm39mm39
GRCm38140,222,480 - 40,316,201 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl140,225,080 - 40,317,257 (+)EnsemblGRCm38mm10GRCm38
MGSCv37140,281,925 - 40,373,022 (+)NCBIGRCm37mm9NCBIm37
MGSCv36140,169,626 - 40,260,723 (+)NCBImm8
Celera140,033,653 - 40,127,353 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map118.81NCBI
Il1r1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554707,685,498 - 7,703,374 (+)NCBIChiLan1.0ChiLan1.0
IL1R1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A103,151,559 - 103,230,005 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A103,193,131 - 103,230,005 (+)Ensemblpanpan1.1panPan2
IL1R1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1040,827,377 - 40,897,596 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11040,825,986 - 40,897,898 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Il1r1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936713808,761 - 881,070 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL1R1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl352,192,914 - 52,288,515 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1352,192,912 - 52,334,734 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2354,729,121 - 54,757,667 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL1R1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1145,781,486 - 5,852,872 (+)NCBI
ChlSab1.1 Ensembl145,781,479 - 5,855,942 (+)Ensembl
Il1r1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247496,661,142 - 6,737,988 (+)NCBI

Position Markers
RH94740  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0947,029,433 - 47,029,544NCBIRnor6.0
Rnor_5.0946,714,686 - 46,714,797UniSTSRnor5.0
RGSC_v3.4939,467,710 - 39,467,821UniSTSRGSC3.4
Celera940,317,888 - 40,317,999UniSTS
RH 3.4 Map9396.1UniSTS
Cytogenetic Map9q21UniSTS
RH94741  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0947,035,248 - 47,035,358NCBIRnor6.0
Rnor_5.0946,720,501 - 46,720,611UniSTSRnor5.0
RGSC_v3.4939,473,525 - 39,473,635UniSTSRGSC3.4
Celera940,323,703 - 40,323,813UniSTS
Cytogenetic Map9q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9105522293442944Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9235572247355722Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9235572247355722Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9288097747375681Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9288097747880977Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9498609549986095Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9498609549986095Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)91221677157216771Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)91242546357425463Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)91242546357425463Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91555490147249201Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92488509969885099Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92569234292741406Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92569237370692373Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92575432054885226Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92748603663264281Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92748603666757620Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92748615588333183Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92907507983686404Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)929075079122095297Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)929466970107878528Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93238513377385133Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93764235182642351Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93764235182642351Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)94126103490024806Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94126103498606834Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)941261034102531865Rat
6903941Pur31Proteinuria QTL 310.036total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94657976991579769Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94657976991579769Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94695242783686153Rat


Genetic Models
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:78
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000019673
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 34 32 31 9 31 3 25 11
Low 2 9 25 10 10 10 8 11 74 32 15 8
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_013123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB079118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB112436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB112437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB112438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M95578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U14010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000019673   ⟹   ENSRNOP00000019673
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl946,996,156 - 47,035,369 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082146   ⟹   ENSRNOP00000073880
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl946,962,288 - 47,036,670 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082408   ⟹   ENSRNOP00000072248
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl946,997,798 - 47,035,275 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087112   ⟹   ENSRNOP00000075417
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl946,997,798 - 47,035,275 (+)Ensembl
RefSeq Acc Id: NM_013123   ⟹   NP_037255
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,540,359 - 42,578,094 (+)NCBI
Rnor_6.0946,997,798 - 47,035,275 (+)NCBI
Rnor_5.0946,647,422 - 46,723,241 (+)NCBI
RGSC_v3.4939,434,910 - 39,473,552 (+)RGD
Celera940,285,956 - 40,323,730 (+)RGD
Sequence:
RefSeq Acc Id: XM_006244746   ⟹   XP_006244808
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,537,004 - 42,580,958 (+)NCBI
Rnor_6.0946,994,372 - 47,038,139 (+)NCBI
Rnor_5.0946,647,422 - 46,723,241 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244747   ⟹   XP_006244809
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,504,917 - 42,580,958 (+)NCBI
Rnor_6.0946,962,291 - 47,038,139 (+)NCBI
Rnor_5.0946,647,422 - 46,723,241 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244748   ⟹   XP_006244810
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,504,917 - 42,580,958 (+)NCBI
Rnor_6.0946,962,291 - 47,038,139 (+)NCBI
Rnor_5.0946,647,422 - 46,723,241 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244749   ⟹   XP_006244811
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,540,308 - 42,580,958 (+)NCBI
Rnor_6.0946,996,559 - 47,038,139 (+)NCBI
Rnor_5.0946,647,422 - 46,723,241 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244750   ⟹   XP_006244812
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,537,005 - 42,580,958 (+)NCBI
Rnor_6.0946,994,372 - 47,038,139 (+)NCBI
Rnor_5.0946,647,422 - 46,723,241 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244751   ⟹   XP_006244813
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,540,384 - 42,580,958 (+)NCBI
Rnor_6.0946,996,559 - 47,038,139 (+)NCBI
Rnor_5.0946,647,422 - 46,723,241 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244752   ⟹   XP_006244814
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,504,917 - 42,580,958 (+)NCBI
Rnor_6.0946,962,291 - 47,038,139 (+)NCBI
Rnor_5.0946,647,422 - 46,723,241 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244753   ⟹   XP_006244815
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0946,962,291 - 47,038,139 (+)NCBI
Rnor_5.0946,647,422 - 46,723,241 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244754   ⟹   XP_006244816
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,537,005 - 42,580,958 (+)NCBI
Rnor_6.0946,994,372 - 47,038,139 (+)NCBI
Rnor_5.0946,647,422 - 46,723,241 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008766993   ⟹   XP_008765215
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,540,364 - 42,580,958 (+)NCBI
Rnor_6.0946,996,559 - 47,038,139 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083091   ⟹   XP_038939019
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,504,917 - 42,580,958 (+)NCBI
RefSeq Acc Id: XM_039083092   ⟹   XP_038939020
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2942,504,938 - 42,580,958 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_037255   ⟸   NM_013123
- UniProtKB: Q05KR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244809   ⟸   XM_006244747
- Peptide Label: isoform X1
- UniProtKB: Q05KR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244814   ⟸   XM_006244752
- Peptide Label: isoform X3
- UniProtKB: Q05KR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244810   ⟸   XM_006244748
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K6N4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244815   ⟸   XM_006244753
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006244808   ⟸   XM_006244746
- Peptide Label: isoform X1
- UniProtKB: Q05KR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244812   ⟸   XM_006244750
- Peptide Label: isoform X3
- UniProtKB: Q05KR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244816   ⟸   XM_006244754
- Peptide Label: isoform X3
- UniProtKB: Q05KR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244811   ⟸   XM_006244749
- Peptide Label: isoform X3
- UniProtKB: Q05KR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244813   ⟸   XM_006244751
- Peptide Label: isoform X3
- UniProtKB: Q05KR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765215   ⟸   XM_008766993
- Peptide Label: isoform X3
- UniProtKB: Q05KR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073880   ⟸   ENSRNOT00000082146
RefSeq Acc Id: ENSRNOP00000072248   ⟸   ENSRNOT00000082408
RefSeq Acc Id: ENSRNOP00000075417   ⟸   ENSRNOT00000087112
RefSeq Acc Id: ENSRNOP00000019673   ⟸   ENSRNOT00000019673
RefSeq Acc Id: XP_038939019   ⟸   XM_039083091
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038939020   ⟸   XM_039083092
- Peptide Label: isoform X3
Protein Domains
Ig-like   Ig-like C2-type   TIR

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696638
Promoter ID:EPDNEW_R7154
Type:initiation region
Name:Il1r1_1
Description:interleukin 1 receptor type 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7155  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0946,962,357 - 46,962,417EPDNEW
RGD ID:13696632
Promoter ID:EPDNEW_R7155
Type:initiation region
Name:Il1r1_2
Description:interleukin 1 receptor type 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7154  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0946,996,187 - 46,996,247EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2892 AgrOrtholog
Ensembl Genes ENSRNOG00000014504 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000019673 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000072248 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000073880 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000075417 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019673 UniProtKB/TrEMBL
  ENSRNOT00000082146 UniProtKB/TrEMBL
  ENSRNOT00000082408 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000087112 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.10140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_rcpt_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_rcpt_I-typ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_rcpt_I/II-typ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25663 UniProtKB/TrEMBL
NCBI Gene 25663 ENTREZGENE
PANTHER PTHR11890 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB IL1R1 RGD
PhenoGen Il1r1 PhenoGen
PRINTS INTRLEUKN1R1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTRLKN1R12F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC236650
UniProt A0A0G2K2H8_RAT UniProtKB/TrEMBL
  A0A0G2K6N4 ENTREZGENE, UniProtKB/TrEMBL
  IL1R1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q05KR0 ENTREZGENE, UniProtKB/TrEMBL
  Q05KR1 ENTREZGENE, UniProtKB/TrEMBL
  Q05KR2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Il1r1  Interleukin 1 receptor, type I      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_process involved in induction of substance P (SP) gene expression 729006