Il1rap (interleukin 1 receptor accessory protein)

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Gene: Il1rap (interleukin 1 receptor accessory protein) Rattus norvegicus

Analyze

Symbol:

Il1rap

Name:

interleukin 1 receptor accessory protein

RGD ID:

2893

Description:

Enables interleukin-1 receptor binding activity. Predicted to be involved in several processes, including interleukin-33-mediated signaling pathway; positive regulation of cytokine production; and regulation of synapse assembly. Predicted to act upstream of or within cytokine-mediated signaling pathway and positive regulation of dendrite development. Located in cytoplasm. Part of protein-containing complex. Orthologous to human IL1RAP (interleukin 1 receptor accessory protein); PARTICIPATES IN interleukin-1 signaling pathway; apoptotic cell death pathway; cytokine mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

IL-1 receptor accessory protein; IL-1RAcp; Il1racpb; interleukin-1 receptor accessory protein; MGC114349

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	11	74,062,999 - 74,199,530 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	74,070,304 - 74,199,530 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	82,878,646 - 83,008,143 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	11	75,513,692 - 75,643,189 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	11	74,567,675 - 74,697,315 (-)	NCBI	Rnor_WKY
Rnor_6.0	11	77,456,648 - 77,593,208 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	77,463,954 - 77,593,207 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	83,123,891 - 83,260,450 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	76,092,252 - 76,222,576 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	76,157,597 - 76,280,084 (-)	NCBI
Celera	11	72,986,798 - 73,116,646 (-)	NCBI		Celera
Cytogenetic Map	11	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Disease Progression (ISO)

head and neck squamous cell carcinoma (ISO)

hepatocellular carcinoma (ISO)

High Myopia (ISO)

liver disease (ISO)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

aripiprazole (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium selenide (ISO)

calcitriol (ISO)

CGP 52608 (ISO)

ciprofibrate (ISO)

cisplatin (EXP,ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cyproconazole (ISO)

dexamethasone (ISO)

dorsomorphin (ISO)

doxorubicin (EXP)

epoxiconazole (ISO)

erlotinib hydrochloride (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

febuxostat (ISO)

fenamidone (ISO)

fipronil (EXP)

flavonoids (EXP)

flutamide (EXP)

gentamycin (EXP)

imiquimod (ISO)

indometacin (ISO)

lead(0) (ISO)

lead(2+) (ISO)

leflunomide (EXP)

lidocaine (EXP)

lipopolysaccharide (ISO)

mercury dibromide (ISO)

methapyrilene (ISO)

methidathion (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N,N-diethyl-m-toluamide (EXP)

N-methylformamide (ISO)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

nitrobenzenes (EXP)

omega-6 fatty acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

permethrin (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

phorbol 13-acetate 12-myristate (ISO)

pinosylvin (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

propiconazole (ISO)

quercetin (ISO)

raloxifene (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

Soman (EXP)

sunitinib (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trans-pinosylvin (ISO)

trichloroethene (ISO)

triptonide (ISO)

troglitazone (ISO)

valproic acid (ISO)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytokine-mediated signaling pathway (IEA,ISO)

inflammatory response (IEA)

interleukin-33-mediated signaling pathway (IEA,ISO)

positive regulation of dendrite development (ISO)

positive regulation of interleukin-13 production (IEA,ISO)

positive regulation of interleukin-4 production (IEA,ISO)

positive regulation of interleukin-5 production (IEA,ISO)

positive regulation of interleukin-6 production (IEA,ISO)

positive regulation of NF-kappaB transcription factor activity (IBA,IEA,ISO)

positive regulation of synapse assembly (IEA,ISO,ISS)

regulation of postsynaptic density assembly (IEA,ISO)

regulation of presynapse assembly (IEA,ISO)

synaptic membrane adhesion (IEA,ISO)

trans-synaptic signaling by trans-synaptic complex (IEA,ISO)

Cellular Component

cytoplasm (IDA)

glutamatergic synapse (IEA,ISO)

membrane (IEA)

protein-containing complex (IDA)

synapse (ISO)

Molecular Function

hydrolase activity (IEA)

interleukin-1 binding (TAS)

interleukin-1 receptor activity (IBA,IEA,ISO)

interleukin-1 receptor binding (IBA,IPI,TAS)

interleukin-33 receptor activity (IEA,ISO)

NAD(P)+ nucleosidase activity (IEA)

NAD+ nucleotidase, cyclic ADP-ribose generating (IEA)

protein binding (ISO)

protein tyrosine kinase binding (ISO)

protein-macromolecule adaptor activity (TAS)

Molecular Pathway Annotations Click to see Annotation Detail View

apoptotic cell death pathway (IEA)

cytokine mediated signaling pathway (IEA)

interleukin-1 signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Distribution of interleukin-1 receptor complex at the synaptic membrane driven by interleukin-1beta and NMDA stimulation.	Gardoni F, etal., J Neuroinflammation. 2011 Feb 11;8(1):14.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat homolog of mouse interleukin-1 receptor accessory protein: cloning, localization and modulation studies.	Liu C, etal., J Neuroimmunol 1996 May;66(1-2):41-8.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	The IL-1 family: regulators of immunity.	Sims JE and Smith DE, Nat Rev Immunol. 2010 Feb;10(2):89-102. Epub 2010 Jan 18.
12.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:11880380	PMID:12477932	PMID:15030977	PMID:17675517	PMID:18003919	PMID:19198660	PMID:19946888	PMID:22357843	PMID:22871113	PMID:24006456	PMID:25908590	PMID:27440742

Genomics

Comparative Map Data

Il1rap
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	11	74,062,999 - 74,199,530 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	74,070,304 - 74,199,530 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	82,878,646 - 83,008,143 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	11	75,513,692 - 75,643,189 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	11	74,567,675 - 74,697,315 (-)	NCBI	Rnor_WKY
Rnor_6.0	11	77,456,648 - 77,593,208 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	77,463,954 - 77,593,207 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	83,123,891 - 83,260,450 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	76,092,252 - 76,222,576 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	76,157,597 - 76,280,084 (-)	NCBI
Celera	11	72,986,798 - 73,116,646 (-)	NCBI		Celera
Cytogenetic Map	11	q22	NCBI

IL1RAP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	190,514,085 - 190,659,750 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	3	190,514,051 - 190,659,750 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	190,231,874 - 190,377,539 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	191,714,585 - 191,851,995 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	191,714,592 - 191,830,773	NCBI
Celera	3	188,662,339 - 188,805,268 (+)	NCBI		Celera
Cytogenetic Map	3	q28	NCBI
HuRef	3	187,631,658 - 187,775,020 (+)	NCBI		HuRef
CHM1_1	3	190,195,381 - 190,338,509 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	193,330,399 - 193,476,092 (+)	NCBI		T2T-CHM13v2.0

Il1rap
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	26,400,259 - 26,548,878 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	26,400,454 - 26,548,867 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	26,581,509 - 26,730,128 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	26,581,704 - 26,730,117 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	26,581,791 - 26,725,233 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	26,497,122 - 26,631,799 (+)	NCBI		MGSCv36	mm8
Celera	16	27,124,937 - 27,269,259 (+)	NCBI		Celera
Cytogenetic Map	16	B2	NCBI

Il1rap
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	17,463,852 - 17,591,023 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	17,463,493 - 17,591,054 (-)	NCBI	ChiLan1.0	ChiLan1.0

IL1RAP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	196,089,340 - 196,232,236 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	196,089,208 - 196,231,379 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	3	187,535,880 - 187,680,628 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

IL1RAP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	22,547,422 - 22,628,628 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	22,546,899 - 22,623,544 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	26,593,650 - 26,721,856 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	22,434,081 - 22,562,566 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	22,434,042 - 22,557,836 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	22,455,737 - 22,584,041 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	22,442,654 - 22,570,368 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	22,684,947 - 22,812,908 (+)	NCBI		UU_Cfam_GSD_1.0

Il1rap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	113,537,247 - 113,675,115 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004937049	48,274 - 181,281 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004937049	48,267 - 185,766 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL1RAP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	127,933,693 - 128,043,480 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	127,933,239 - 128,071,984 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	137,204,766 - 137,370,308 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL1RAP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	84,728,594 - 84,876,098 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	84,728,517 - 84,866,263 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	58,314,327 - 58,465,943 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Il1rap
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	66,491,230 - 66,625,642 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Il1rap
857 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	195
Count of miRNA genes:	134
Interacting mature miRNAs:	159
Transcripts:	ENSRNOT00000002645, ENSRNOT00000043498
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	27672410	82846715	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	29528418	82566702	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	31239134	78851519	Rat
70180	BpQTLcluster10	Blood pressure QTL cluster 10	3.19		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	11	34918041	79918041	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	40946188	82566702	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	44285759	82566702	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	45459323	75190161	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	54457534	86241447	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	55136729	82993457	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	56351424	86241447	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	59802794	82566545	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	59802794	82566553	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	60346590	86241447	Rat
1549848	Bvd6	Brain ventricular dilatation QTL 6	3.1	0.0001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	66113321	82169223	Rat
634339	Niddm50	Non-insulin dependent diabetes mellitus QTL 50	3.32		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	66422148	86241447	Rat
1354593	Stl12	Serum triglyceride level QTL 12	3.36		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	11	66422148	86241447	Rat
1354656	Bvd3	Brain ventricular dilatation QTL 3	3.64	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	69446070	82846715	Rat

Markers in Region

D11Rat92

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	74,106,772 - 74,106,899 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	77,500,524 - 77,500,650	NCBI	Rnor6.0
Rnor_5.0	11	83,216,448 - 83,216,574	UniSTS	Rnor5.0
RGSC_v3.4	11	76,129,617 - 76,129,984	RGD	RGSC3.4
RGSC_v3.4	11	76,129,817 - 76,129,943	UniSTS	RGSC3.4
RGSC_v3.1	11	76,187,406 - 76,187,532	RGD
Celera	11	73,023,951 - 73,024,077	UniSTS
RH 3.4 Map	11	601.3	RGD
RH 3.4 Map	11	601.3	UniSTS
RH 2.0 Map	11	90.0	RGD
SHRSP x BN Map	11	35.6998	RGD
Cytogenetic Map	11	q22	UniSTS

RH133894

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	74,081,027 - 74,082,650 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	77,474,781 - 77,476,403	NCBI	Rnor6.0
Rnor_5.0	11	83,240,695 - 83,242,317	UniSTS	Rnor5.0
RGSC_v3.4	11	76,103,304 - 76,104,926	UniSTS	RGSC3.4
Celera	11	72,998,211 - 72,999,833	UniSTS
RH 3.4 Map	11	601.9	UniSTS
Cytogenetic Map	11	q22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			34	29		29			25	10	1	10
Low	3	43	23	12	19	12	8	11	49	25	40	1	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001167840	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_012968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248504	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005490978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005490979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005490980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005490981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB079119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC097339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GU123169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U48592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000002645 ⟹ ENSRNOP00000002645

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	74,078,061 - 74,199,449 (-)	Ensembl
Rnor_6.0 Ensembl	11	77,471,558 - 77,593,171 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000043498 ⟹ ENSRNOP00000051260

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	74,070,305 - 74,199,530 (-)	Ensembl
Rnor_6.0 Ensembl	11	77,463,954 - 77,593,207 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000105096 ⟹ ENSRNOP00000090112

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	74,070,304 - 74,199,530 (-)	Ensembl

RefSeq Acc Id:

NM_001167840 ⟹ NP_001161312

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	74,070,304 - 74,199,530 (-)	NCBI
Rnor_6.0	11	77,463,953 - 77,593,207 (-)	NCBI
Rnor_5.0	11	83,123,891 - 83,260,450 (+)	NCBI
RGSC_v3.4	11	76,092,252 - 76,222,576 (-)	RGD
Celera	11	72,986,798 - 73,116,646 (-)	RGD

Sequence:

show sequence

GGGAAGGGACTCCGGAGGGGGAAAAAGAAAGTGCGGCGGAAAGTAAGAGGCTAGTCGGGGAAGG
CTGCCAGCATCTGGGTCTCCTGGGTTCCGCTTGGACCAGGGCGCTGAAGGAGGCAGTGGCCGGC
CAACCCGCACCCATCTGGTCGCTGTCGCCGAGCCTGCTTGGCTGGCCCAGTAAGGATGGGACTT
CCTTGGTGTTTGATGAGTCTGTTCTTCTGTGGGATCCTGCAGAGTCACGCTTCCGAACGCTGTG
ATGACTGGGGACTAGATACCATGCGACAAATCCAAGTGTTTGAAGATGAGCCAGCTCGCATCAA
GTGCCCCCTCTTTGAACACTTCTTGAAGTACAACTACAGCACTGCCCATTCCTCTGGACTTACC
CTGATCTGGTACTGGACCAGGCAAGACCGGGACCTGGAGGAGCCCATTAATTTCCGCCTTCCAG
AGAATCGCATCAGTAAGGAGAAAGATGTGCTCTGGTTCCGGCCCACCCTCCTCAATGACACGGG
CAATTACACCTGCATGTTGAGGAACACGACTTACTGCAGCAAAGTTGCATTTCCCCTGGAAGTT
GTTCAGAAGGACAGCTGTTTCAATTCCCCCATGAGACTCCCAGTGCACAGGCTGTATATTGAAC
AGGGTATTCACAATATCACGTGTCCAAATGTAGATGGATATTTTCCTTCCAGTGTCAAACCATC
GGTCACTTGGTATAAGGGTTGTACTGAAATAGTGAATTTTCATAATGTTCAACCCAAGGGCATG
AACTTGAGTTTTTTCATCCCCTTGGTATCAAATAACGGAAATTACACATGTGTGGTGACGTATC
TGGAAAACGGACGGCTCTTTCACCTCACCAGGACTATGACTGTAAAGGTGGTAGGCTCACCAAA
GGATGCAGTACCACCTCATATCTACTCGCCAAATGACCGCGTTGTCTATGAGAAGGAACCAGGA
GAGGAGTTGGTTATTCCCTGTAAAGTCTATTTCAGTTTCATTATGGACTCTCACAATGAGATCT
GGTGGACCATTGATGGAAAGAAGCCTGATGACGTCCCTGTTGACATCACTATTAATGAAAGCGT
AAGTTATTCTTCAACGGAAGATGAGACAAGGACTCAGATTTTGAGCATCAAGAAAGTCACCCCT
GAGGATCTGAAGCGCAACTATGTCTGTCACGCTCGAAATGCCGAAGGGGAAGCCGAGCAAGCAG
CCAAGGTGAAACAGAAAGTCATACCGCCAAGGTACACAGTAGAACTCGCCTGTGGTTTTGGAGC
CACAGTCTTTCTGGTGGTGGTTCTCATCGTGGTTTACCACGTTTACTGGCTGGAGATGGTCCTC
TTTTACCGGGCTCATTTTGGAACGGATGAAACAATTCTTGATGGAAAAGAATATGATATTTATG
TTTCCTATGCAAGAAATGCAGAAGAAGAGGAGTTTGTGCTGCTGACACTACGTGGAGTTTTGGA
GAATGAGTTCGGATACAAGCTGTGCATCTTCGACAGGGACAGCCTCCCTGGGGGAAATACGGTG
GAAGCAGTGTTTGATTTCATTCAGCGGAGCCGAAGGATGATTGTTGTCCTGAGCCCAGACTATG
TGACAGAAAAGAGCATCAGTATGCTGGAGTTTAAGCTGGGTGTCATGTGCCAGAACTCCATTGC
CACTAAGCTCATTGTGGTGGAGTACCGTCCGCTTGAGCAACCCCACCCAGGCATTATGCAGCTG
AAAGAGTCTGTGTCTTTCGTAAGCTGGAAGGGAGAAAAGTCCAAACATTCTGGCTCCAAGTTCT
GGAAGGCCTTGCGCTTGGCTCTTCCCCTGAGAAGTCTGAGCGCCAGCTCCGGTTGGAATGAGAG
CTGTTCTTCTCAGTCTGACATCAGTCTGGATCATGTTCAGAGGAGAAGTCGTTTGAAAGAGCCC
CCAGAACTTCAAAGCTCAGAGAGGGTGTCTGGAGCAGCGCCAGCCCCGGGCACCATATCCAAGC
ACCGAGGCAAGCCCTCGGCAGCCTGTCGCTGCTGTGTCACCTACTGTGAAGGAGAAAGTCACCT
CAGGAGCAAGAGCCGGGCAGAGATGCACACCCATCCCCAATGGGAAACACACCTCTGTAAGCCT
GATCTCCAAGAGTCTGAAAGTCAGTGGATACAAAATGGCACCAGACCCGAACCCGCTCCCCAGA
TCTCAGCTCTTGCACTCCGCCATTTTACAGATTTATCCAATAACAATGACTTTTATATTCTATA
ATCACTTTATGTGGAGGGTGGTGGCTGCTATTTCTACCAACTCTCGTTGGGTCACAAACTTTTG
GGAATAATAGACATTTTTAATCATTTAATAGACTATCAGATTTGTGTCCCCTTTTATTGATTTT
TTTTAAAAACTATTCATTTCTAGGAGACAAAAGACCTGAAGCACCTGTATCCAGTTATTGCCTC
TAATGGCCTTGGAAGAGCACACTCTTCTCGGGCCCTAGAAGGTCAGTATGTAAAAGTTGCTTTG
AGTCTGATCTAGCCCCGTGGTTCAAAGGTAGCTAAGCATTGCTGTCTCCTTGTGATATAGGTCA
ATGAAGTGTACTTGGGCTTTGACACTCACAGAGTGTATGCACCCAAAAGACCAGGGCTGTGACA
CTCTCAGGGTGTGTGTACCCCAAGGAGCGACTTGAGAAGGAGCAGGTTCTGGTGGACATTGTAG
GACAGAGCTCAGCAGCAAACCTACAGCACATTTTGCCCCCAGGGACCAAATCTTCCCACAGGAA
CTCCCGCTTCCCATTTCCCCCTGTAAATAATATGCTTTTTGTTGCCAGTCTCAATAAAGGTATA
TTTTTATGCCAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_012968 ⟹ NP_037100

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	74,078,061 - 74,199,449 (-)	NCBI
Rnor_6.0	11	77,471,710 - 77,593,126 (-)	NCBI
Rnor_5.0	11	83,123,891 - 83,260,450 (+)	NCBI
RGSC_v3.4	11	76,092,252 - 76,222,576 (-)	RGD
Celera	11	72,994,555 - 73,116,565 (-)	NCBI

Sequence:

show sequence

TCCTGGGTTCCGCTTGGACCAGGGCGCTGAAGGAGGCAGTGGCCGGCCAACCCGCACCCATCTG
GTCGCTGTCGCCGAGCCTGCTTGGCTGGCCCAGTAAGGATGGGACTTCCTTGGTGTTTGATGAG
TCTGTTCTTCTGTGGGATCCTGCAGAGTCACGCTTCCGAACGCTGTGATGACTGGGGACTAGAT
ACCATGCGACAAATCCAAGTGTTTGAAGATGAGCCAGCTCGCATCAAGTGCCCCCTCTTTGAAC
ACTTCTTGAAGTACAACTACAGCACTGCCCATTCCTCTGGACTTACCCTGATCTGGTACTGGAC
CAGGCAAGACCGGGACCTGGAGGAGCCCATTAATTTCCGCCTTCCAGAGAATCGCATCAGTAAG
GAGAAAGATGTGCTCTGGTTCCGGCCCACCCTCCTCAATGACACGGGCAATTACACCTGCATGT
TGAGGAACACGACTTACTGCAGCAAAGTTGCATTTCCCCTGGAAGTTGTTCAGAAGGACAGCTG
TTTCAATTCCCCCATGAGACTCCCAGTGCACAGGCTGTATATTGAACAGGGTATTCACAATATC
ACGTGTCCAAATGTAGATGGATATTTTCCTTCCAGTGTCAAACCATCGGTCACTTGGTATAAGG
GTTGTACTGAAATAGTGAATTTTCATAATGTTCAACCCAAGGGCATGAACTTGAGTTTTTTCAT
CCCCTTGGTATCAAATAACGGAAATTACACATGTGTGGTGACGTATCTGGAAAACGGACGGCTC
TTTCACCTCACCAGGACTATGACTGTAAAGGTGGTAGGCTCACCAAAGGATGCAGTACCACCTC
ATATCTACTCGCCAAATGACCGCGTTGTCTATGAGAAGGAACCAGGAGAGGAGTTGGTTATTCC
CTGTAAAGTCTATTTCAGTTTCATTATGGACTCTCACAATGAGATCTGGTGGACCATTGATGGA
AAGAAGCCTGATGACGTCCCTGTTGACATCACTATTATTGAAAGCGTAAGTTATTCTTCAACGG
AAGATGAGACAAGGACTCAGATTTTGAGCATCAAGAAAGTCACCCCTGAGGATCTGAAGCGCAA
CTATGTCTGTCACGCTCGAAATGCCGAAGGGGAAGCCGAGCAAGCAGCCAAGGTGAAACAGAAA
GTCATACCGCCAAGGTACACAGTAGAACTCGCCTGTGGTTTTGGAGCCACAGTCTTTCTGGTGG
TGGTTCTCATCGTGGTTTACCACGTTTACTGGCTGGAGATGGTCCTCTTTTACCGGGCTCATTT
TGGAACGGATGAAACAATTCTTGACGGAAAAGAATATGATATTTATGTTTCCTATGCAAGAAAT
GCAGAAGAAGAAGAGTTTGTGCTGCTGACACTACGTGGAGTTTTGGAGAATGAGTTCGGATACA
AGCTGTGCATCTTCGACAGGGACAGCTTCCCTGGGGGAATTGTCACAGATGAGACCCTGAGCTT
CATTCAGAAAAGCAGACGACTCCTGGTTGTCCTAAGCCCCAACTACGTGCTCCAGGGAACACAA
GCCCTCCTGGAGCTCAAGGCTGGCCTAGAAAATATGGCCTCCCGGGGCAACATCAACGTCATTT
TAGTGCAGTACAAAGCTGTGAAGGACTTGAAGGTGAAAGAGCTGAAGCGGGCTAAGTCGGTGCT
CACCGTCATTAAATGGAAAGGGGAGAAATCCAAGTATCCTCAGGGCAGGTTCTGGAAGCAGCTG
CAGGTGGCCATGCCAGTGAAGAAGAGTCCCAGGTGGTCTAGCAGTGACAAGCAGGGTCTCTCCT
ACTCATCCCTGAAAAACGTATGAAAGGAAAAGTCAGGGGGTGAAAAGAACAAGGCGGTTCATGG
GAGGAA

hide sequence

RefSeq Acc Id:

XM_039088037 ⟹ XP_038943965

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	74,062,999 - 74,156,842 (-)	NCBI

RefSeq Acc Id:

XM_039088038 ⟹ XP_038943966

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	74,062,999 - 74,199,526 (-)	NCBI

RefSeq Acc Id:

XM_039088039 ⟹ XP_038943967

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	74,062,999 - 74,156,840 (-)	NCBI

RefSeq Acc Id:

XM_039088040 ⟹ XP_038943968

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	74,075,385 - 74,156,834 (-)	NCBI

RefSeq Acc Id:

XR_005490978

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	74,062,999 - 74,156,842 (-)	NCBI

RefSeq Acc Id:

XR_005490979

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	74,062,999 - 74,156,842 (-)	NCBI

RefSeq Acc Id:

XR_005490980

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	74,062,999 - 74,156,840 (-)	NCBI

RefSeq Acc Id:

XR_005490981

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	74,062,999 - 74,156,840 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001161312	(Get FASTA)	NCBI Sequence Viewer
	NP_037100	(Get FASTA)	NCBI Sequence Viewer
	XP_038943965	(Get FASTA)	NCBI Sequence Viewer
	XP_038943966	(Get FASTA)	NCBI Sequence Viewer
	XP_038943967	(Get FASTA)	NCBI Sequence Viewer
	XP_038943968	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB03502	(Get FASTA)	NCBI Sequence Viewer
	AAH97339	(Get FASTA)	NCBI Sequence Viewer
	ACY68959	(Get FASTA)	NCBI Sequence Viewer
	BAD15354	(Get FASTA)	NCBI Sequence Viewer
	EDL78120	(Get FASTA)	NCBI Sequence Viewer
	Q63621	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_037100 ⟸ NM_012968
- Peptide Label:	precursor
- UniProtKB:	Q63621 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGLPWCLMSLFFCGILQSHASERCDDWGLDTMRQIQVFEDEPARIKCPLFEHFLKYNYSTAHSS GLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYCSKVAFP LEVVQKDSCFNSPMRLPVHRLYIEQGIHNITCPNVDGYFPSSVKPSVTWYKGCTEIVNFHNVQP KGMNLSFFIPLVSNNGNYTCVVTYLENGRLFHLTRTMTVKVVGSPKDAVPPHIYSPNDRVVYEK EPGEELVIPCKVYFSFIMDSHNEIWWTIDGKKPDDVPVDITIIESVSYSSTEDETRTQILSIKK VTPEDLKRNYVCHARNAEGEAEQAAKVKQKVIPPRYTVELACGFGATVFLVVVLIVVYHVYWLE MVLFYRAHFGTDETILDGKEYDIYVSYARNAEEEEFVLLTLRGVLENEFGYKLCIFDRDSFPGG IVTDETLSFIQKSRRLLVVLSPNYVLQGTQALLELKAGLENMASRGNINVILVQYKAVKDLKVK ELKRAKSVLTVIKWKGEKSKYPQGRFWKQLQVAMPVKKSPRWSSSDKQGLSYSSLKNV hide sequence

RefSeq Acc Id:	NP_001161312 ⟸ NM_001167840
- Peptide Label:	isoform b precursor
- UniProtKB:	D1M8S3 (UniProtKB/TrEMBL), F1LRE8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGLPWCLMSLFFCGILQSHASERCDDWGLDTMRQIQVFEDEPARIKCPLFEHFLKYNYSTAHSS GLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYCSKVAFP LEVVQKDSCFNSPMRLPVHRLYIEQGIHNITCPNVDGYFPSSVKPSVTWYKGCTEIVNFHNVQP KGMNLSFFIPLVSNNGNYTCVVTYLENGRLFHLTRTMTVKVVGSPKDAVPPHIYSPNDRVVYEK EPGEELVIPCKVYFSFIMDSHNEIWWTIDGKKPDDVPVDITINESVSYSSTEDETRTQILSIKK VTPEDLKRNYVCHARNAEGEAEQAAKVKQKVIPPRYTVELACGFGATVFLVVVLIVVYHVYWLE MVLFYRAHFGTDETILDGKEYDIYVSYARNAEEEEFVLLTLRGVLENEFGYKLCIFDRDSLPGG NTVEAVFDFIQRSRRMIVVLSPDYVTEKSISMLEFKLGVMCQNSIATKLIVVEYRPLEQPHPGI MQLKESVSFVSWKGEKSKHSGSKFWKALRLALPLRSLSASSGWNESCSSQSDISLDHVQRRSRL KEPPELQSSERVSGAAPAPGTISKHRGKPSAACRCCVTYCEGESHLRSKSRAEMHTHPQWETHL CKPDLQESESQWIQNGTRPEPAPQISALALRHFTDLSNNNDFYIL hide sequence

RefSeq Acc Id:

ENSRNOP00000051260 ⟸ ENSRNOT00000043498

RefSeq Acc Id:

ENSRNOP00000002645 ⟸ ENSRNOT00000002645

RefSeq Acc Id:	XP_038943966 ⟸ XM_039088038
- Peptide Label:	isoform X2
- UniProtKB:	F1LRE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038943965 ⟸ XM_039088037
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038943967 ⟸ XM_039088039
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038943968 ⟸ XM_039088040
- Peptide Label:	isoform X4

RefSeq Acc Id:

ENSRNOP00000090112 ⟸ ENSRNOT00000105096

Protein Domains

Ig-like Ig-like C2-type TIR

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q63621-F1-model_v2	AlphaFold	Q63621	1-570	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698235

Promoter ID:

EPDNEW_R8760

Type:

single initiation site

Name:

Il1rap_1

Description:

interleukin 1 receptor accessory protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	77,593,155 - 77,593,215	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2893	AgrOrtholog
BioCyc Gene	G2FUF-20943	BioCyc
Ensembl Genes	ENSRNOG00000001928	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000002645	ENTREZGENE
	ENSRNOP00000002645.3	UniProtKB/TrEMBL
	ENSRNOP00000051260	ENTREZGENE
	ENSRNOP00000051260.4	UniProtKB/TrEMBL
	ENSRNOP00000090112.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000002645	ENTREZGENE
	ENSRNOT00000002645.5	UniProtKB/TrEMBL
	ENSRNOT00000043498	ENTREZGENE
	ENSRNOT00000043498.7	UniProtKB/TrEMBL
	ENSRNOT00000105096.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.40.50.10140	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7442849	IMAGE-MGC_LOAD
InterPro	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL-1_rcpt_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL-1_rcpt_I/II-typ	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TIR_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Toll_tir_struct_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25466	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114349	IMAGE-MGC_LOAD
NCBI Gene	25466	ENTREZGENE
PANTHER	PTHR11890	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Ig_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TIR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Il1rap	PhenoGen
PRINTS	INTRLKN1R12F	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TIR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	SM00409	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TIR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF52200	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC213055
UniProt	A0A8I6ACY6_RAT	UniProtKB/TrEMBL
	D1M8S3	ENTREZGENE, UniProtKB/TrEMBL
	F1LRE8	ENTREZGENE
	F1M9B9_RAT	UniProtKB/TrEMBL
	IL1AP_RAT	UniProtKB/Swiss-Prot
	Q4V8K9_RAT	UniProtKB/TrEMBL
	Q63621	ENTREZGENE
UniProt Secondary	F1LRE8	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Il1rap	Interleukin 1 receptor accessory protein			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains a extracellular domain with three immunoglobulin-like loops, a single transmembrane domain and a long intracellular domain	633114
gene_homology	has > 95% sequence identity to mouse gene	633114

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)