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Gene: Lmbrd1 (LMBR1 domain containing 1) Rattus norvegicus
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Symbol: Lmbrd1
Name: LMBR1 domain containing 1
Description: Predicted to have insulin receptor binding activity. Predicted to be involved in insulin receptor internalization; negative regulation of glucose import; and negative regulation of signal transduction. Predicted to localize to the clathrin-coated endocytic vesicle; lysosome; and plasma membrane. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblF. Orthologous to human LMBRD1 (LMBR1 domain containing 1); INTERACTS WITH ammonium chloride; bisphenol A; clofibric acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: liver regeneration p-53 related protein; LMBR1 domain-containing protein 1; LOC246046; probable lysosomal cobalamin transporter
Orthologs:
Homo sapiens (human) : LMBRD1 (LMBR1 domain containing 1)  HGNC  Alliance
Mus musculus (house mouse) : Lmbrd1 (LMBR1 domain containing 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lmbrd1 (LMBR1 domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LMBRD1 (LMBR1 domain containing 1)
Canis lupus familiaris (dog) : LMBRD1 (LMBR1 domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lmbrd1 (LMBR1 domain containing 1)
Sus scrofa (pig) : LMBRD1 (LMBR1 domain containing 1)
Chlorocebus sabaeus (African green monkey) : LMBRD1 (LMBR1 domain containing 1)
Heterocephalus glaber (naked mole-rat) : Lmbrd1 (LMBR1 domain containing 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0930,939,555 - 31,038,381 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl930,939,555 - 31,038,379 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0929,762,573 - 29,854,653 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4923,426,569 - 23,511,388 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1923,438,200 - 23,512,800 (+)NCBI
Celera924,630,912 - 24,711,848 (+)NCBICelera
Cytogenetic Map9q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lmbrd1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708471
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.