 Gene Ontology Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Component
Molecular Function
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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
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Gene Annotator (Annotation Comparison) |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Cellular Component
Molecular Function
Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | Lovenberg TW, etal., J Neuroimmunol 1996 Nov;70(2):113-22. |
| 3. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 4. | RGD automated data pipeline |
| 5. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 6. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Il1rl2 (Rattus norvegicus - Norway rat) |
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| IL1RL2 (Homo sapiens - human) |
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| Il1rl2 (Mus musculus - house mouse) |
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| Il1rl2 (Chinchilla lanigera - long-tailed chinchilla) |
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| IL1RL2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| IL1RL2 (Canis lupus familiaris - dog) |
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| Il1rl2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| IL1RL2 (Sus scrofa - pig) |
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| IL1RL2 (Chlorocebus sabaeus - African green monkey) |
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| Il1rl2 (Heterocephalus glaber - naked mole-rat) |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | |||||||||||||
| Low | 2 | 12 | 12 | 4 | 19 | 4 | 32 | 14 | 31 | 11 | |||
| Below cutoff | 1 | 28 | 36 | 34 | 34 | 5 | 7 | 42 | 20 | 10 | 5 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_133575 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_017596258 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017596259 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017596260 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07067459 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07067460 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059549 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059550 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059551 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059552 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01059553 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473965 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| U49066 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000019880 ⟹ ENSRNOP00000019880 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_133575 ⟹ NP_598259 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
CCGGCTGGCCTAGGATCAGGCAAGAAAAGGCTGAACGCCTTTCTAAGGACGGACTCTTTCTGTAhide sequence |
| RefSeq Acc Id: | XM_017596258 ⟹ XP_017451747 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
TCTAGGAATCATTGCAAATTTGAAAGTCAAAACTGATATCCTTTGAAATGATCATTTCTTTGTChide sequence |
| RefSeq Acc Id: | XM_017596259 ⟹ XP_017451748 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
TCAAGGGACAGTGCCCGGACAGACACCTATCCATCTTAACTTTGTGAACTTGGGACAGCTAGTChide sequence |
| RefSeq Acc Id: | XM_017596260 ⟹ XP_017451749 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
GTTTAAGACTGGGAGTTTGGGTATAGGCGGACAGACACGGGAAGCCAGGAGAAGATTCCTTCTGhide sequence |
Protein Sequences| Protein RefSeqs | NP_598259 | (Get FASTA) | NCBI Sequence Viewer |
| XP_017451747 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017451748 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017451749 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAB53238 | (Get FASTA) | NCBI Sequence Viewer |
| EDL99176 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL99177 | (Get FASTA) | NCBI Sequence Viewer | |
| Q62929 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_598259 ⟸ NM_133575 |
| - Peptide Label: | precursor |
| - UniProtKB: | Q62929 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MGMPPLLFCWVSFVLPLFVAAGNCTDVYMHHEMISEGQPFPFNCTYPPVTNGAVNLTWHRTPSKhide sequence |
| RefSeq Acc Id: | XP_017451747 ⟸ XM_017596258 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MAPCWPGWRDQETSTTNYQPEMGMPPLLFCWVSFVLPLFVAAGNCTDVYMHHEMISEGQPFPFNhide sequence |
| RefSeq Acc Id: | XP_017451749 ⟸ XM_017596260 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | G3V7W4 (UniProtKB/TrEMBL) |
| - Sequence: |
MGMPPLLFCWVSFVLPLFVAAGNCTDVYMHHEMISEGQPFPFNCTYPPVTNGAVNLTWHRTPSKhide sequence |
| RefSeq Acc Id: | XP_017451748 ⟸ XM_017596259 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | G3V7W4 (UniProtKB/TrEMBL) |
| - Sequence: |
MGMPPLLFCWVSFVLPLFVAAGNCTDVYMHHEMISEGQPFPFNCTYPPVTNGAVNLTWHRTPSKhide sequence |
| RefSeq Acc Id: | ENSRNOP00000019880 ⟸ ENSRNOT00000019880 |
Protein Domains
Ig-like Ig-like C2-type TIR
TranscriptomeStrain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:621782 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000014683 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000019880 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000019880 | ENTREZGENE, UniProtKB/TrEMBL |
| Gene3D-CATH | 2.60.40.10 | UniProtKB/Swiss-Prot |
| 3.40.50.10140 | UniProtKB/Swiss-Prot | |
| InterPro | Ig-like_dom | UniProtKB/Swiss-Prot |
| Ig-like_dom_sf | UniProtKB/Swiss-Prot | |
| Ig-like_fold | UniProtKB/Swiss-Prot | |
| Ig_6 | UniProtKB/Swiss-Prot | |
| Ig_sub | UniProtKB/Swiss-Prot | |
| Ig_sub2 | UniProtKB/Swiss-Prot | |
| IL-1_rcpt_fam | UniProtKB/Swiss-Prot | |
| IL-1_rcpt_I/II-typ | UniProtKB/Swiss-Prot | |
| TIR_dom | UniProtKB/Swiss-Prot | |
| Toll_tir_struct_dom_sf | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:171106 | UniProtKB/Swiss-Prot |
| NCBI Gene | 171106 | ENTREZGENE |
| PANTHER | PTHR11890 | UniProtKB/Swiss-Prot |
| Pfam | Ig_2 | UniProtKB/Swiss-Prot |
| Ig_6 | UniProtKB/Swiss-Prot | |
| TIR | UniProtKB/Swiss-Prot | |
| PhenoGen | Il1rl2 | PhenoGen |
| PRINTS | INTRLKN1R12F | UniProtKB/Swiss-Prot |
| PROSITE | IG_LIKE | UniProtKB/Swiss-Prot |
| TIR | UniProtKB/Swiss-Prot | |
| SMART | IGc2 | UniProtKB/Swiss-Prot |
| SM00409 | UniProtKB/Swiss-Prot | |
| TIR | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | SSF48726 | UniProtKB/Swiss-Prot |
| SSF52200 | UniProtKB/Swiss-Prot | |
| UniGene | Rn.10235 | ENTREZGENE |
| UniProt | G3V7W4 | ENTREZGENE, UniProtKB/TrEMBL |
| ILRL2_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2004-09-10 | Il1rl2 | interleukin 1 receptor-like 2 | Symbol and Name status set to approved | 1299863 | APPROVED | ||
| 2002-08-07 | Il1rl2 | interleukin 1 receptor-like 2 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_expression | expressed in lung and epididymis with lower levels of expression detected in the testis and cerebral cortex | 729063 |
| gene_function | did not bind either [125I]-recombinant human IL 1 alpha or [125I]-recombinant human IL 1 beta with high affinity | 729063 |
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| More on Il1rl2 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 621782 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-03-10 |
| Status: | ACTIVE |
