Il1rl2 (interleukin 1 receptor-like 2)

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Gene: Il1rl2 (interleukin 1 receptor-like 2) Rattus norvegicus

Analyze

Symbol:

Il1rl2

Name:

interleukin 1 receptor-like 2

RGD ID:

621782

Description:

Predicted to have NAD(P)+ nucleosidase activity; NAD+ nucleotidase, cyclic ADP-ribose generating; and interleukin-1 receptor activity. Predicted to be involved in positive regulation of T cell differentiation; positive regulation of interleukin-6 production; and regulation of inflammatory response. Predicted to localize to integral component of membrane. Orthologous to human IL1RL2 (interleukin 1 receptor like 2); INTERACTS WITH ammonium chloride; bisphenol A; endosulfan.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

IL-1Rrp2; IL-36 receptor; IL1R-rp2; interleukin-1 receptor-like 2; interleukin-1 receptor-related protein 2

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IL1RL2 (interleukin 1 receptor like 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Il1rl2 (interleukin 1 receptor-like 2)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Il1rl2 (interleukin 1 receptor like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IL1RL2 (interleukin 1 receptor like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IL1RL2 (interleukin 1 receptor like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Il1rl2 (interleukin 1 receptor like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IL1RL2 (interleukin 1 receptor like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	IL1RL2 (interleukin 1 receptor like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Il1rl2 (interleukin 1 receptor like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Il1rl2 (interleukin 1 receptor-like 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	IL1RL2 (interleukin 1 receptor like 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	zmp:0000000936	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|PANTHER\|TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	42,591,658 - 42,639,351 (+)	NCBI
Rnor_6.0 Ensembl	9	47,047,832 - 47,095,831 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	9	47,044,870 - 47,093,679 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	9	46,733,619 - 46,778,352 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	39,492,187 - 39,537,792 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	9	39,493,600 - 39,539,206 (+)	NCBI
Celera	9	40,337,394 - 40,381,411 (+)	NCBI		Celera
Cytogenetic Map	9	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

cadmium atom (ISO)

choline (ISO)

elemental selenium (ISO)

endosulfan (EXP)

ethanol (ISO)

folic acid (ISO)

L-methionine (ISO)

lead diacetate (ISO)

monosodium L-glutamate (ISO)

potassium dichromate (ISO)

selenium atom (ISO)

silver atom (ISO)

silver(0) (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytokine-mediated signaling pathway (IEA)

positive regulation of interleukin-6 production (IEA,ISO)

positive regulation of T cell differentiation (IEA,ISO)

regulation of inflammatory response (IBA,IEA,ISO)

Cellular Component

integral component of membrane (IEA)

Molecular Function

interleukin-1 receptor activity (IEA)

NAD(P)+ nucleosidase activity (IEA)

NAD+ nucleotidase, cyclic ADP-ribose generating (IEA)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Lovenberg TW, etal., J Neuroimmunol 1996 Nov;70(2):113-22.
3.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	RGD automated data pipeline
5.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:21860022	PMID:22968459	PMID:23064362	PMID:32048631

Genomics

Comparative Map Data

Il1rl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	42,591,658 - 42,639,351 (+)	NCBI
Rnor_6.0 Ensembl	9	47,047,832 - 47,095,831 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	9	47,044,870 - 47,093,679 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	9	46,733,619 - 46,778,352 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	39,492,187 - 39,537,792 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	9	39,493,600 - 39,539,206 (+)	NCBI
Celera	9	40,337,394 - 40,381,411 (+)	NCBI		Celera
Cytogenetic Map	9	q22	NCBI

IL1RL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	102,187,006 - 102,240,002 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	102,186,973 - 102,242,910 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	102,803,433 - 102,856,462 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	102,169,865 - 102,222,243 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	102,261,950 - 102,314,329	NCBI
Celera	2	97,004,649 - 97,057,020 (+)	NCBI
Cytogenetic Map	2	q12.1	NCBI
HuRef	2	96,567,290 - 96,619,802 (+)	NCBI		HuRef
CHM1_1	2	102,807,775 - 102,860,073 (+)	NCBI		CHM1_1

Il1rl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	40,363,697 - 40,406,722 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	1	40,363,770 - 40,406,722 (+)	Ensembl
GRCm38	1	40,324,589 - 40,367,555 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	40,324,610 - 40,367,562 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	40,381,472 - 40,422,316 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	1	40,269,173 - 40,310,017 (+)	NCBI			mm8
Celera	1	40,135,784 - 40,176,671 (+)	NCBI		Celera
Cytogenetic Map	1	B	NCBI

Il1rl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955470	7,704,134 - 7,742,064 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955470	7,703,369 - 7,742,058 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL1RL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2A	103,237,107 - 103,289,427 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	103,237,996 - 103,289,414 (+)	Ensembl	panpan1.1		panPan2

IL1RL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	10	40,778,590 - 40,816,044 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	10	40,776,670 - 40,817,263 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Il1rl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936713	893,020 - 932,406 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL1RL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	51,980,026 - 52,011,602 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	51,978,857 - 52,011,607 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	54,382,183 - 54,396,574 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL1RL2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	5,862,140 - 5,912,789 (+)	NCBI
ChlSab1.1 Ensembl	14	5,863,727 - 5,915,370 (+)	Ensembl

Il1rl2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624749	6,747,131 - 6,781,908 (+)	NCBI

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1055222	93442944	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	2355722	47355722	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	2355722	47355722	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	2880977	47375681	Rat
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	2880977	47880977	Rat
1354650	Despr5	Despair related QTL 5	4.01	0.0017	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	9	4986095	49986095	Rat
2303559	Gluco54	Glucose level QTL 54	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	4986095	49986095	Rat
11353947	Bp392	Blood pressure QTL 392			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	12216771	57216771	Rat
9589133	Insul26	Insulin level QTL 26	17.96	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	9	12425463	57425463	Rat
7411609	Foco16	Food consumption QTL 16	25.6	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	12425463	57425463	Rat
1600365	Mcs20	Mammary carcinoma susceptibility QTL 20	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	9	15554901	47249201	Rat
631680	Cm11	Cardiac mass QTL 11	3.1	0.00089	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	9	24885099	69885099	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	25692342	92741406	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	25692373	70692373	Rat
1598823	Memor16	Memory QTL 16	1.9		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	25754320	54885226	Rat
7207805	Bmd88	Bone mineral density QTL 88	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	9	27486036	63264281	Rat
1300180	Bw14	Body weight QTL 14	3.776		body mass (VT:0001259)	body weight (CMO:0000012)	9	27486036	66757620	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	27486155	88333183	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	29075079	83686404	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	29075079	122095297	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	29466970	107878528	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	32385133	77385133	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	37642351	82642351	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	37642351	82642351	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	41261034	90024806	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	41261034	98606834	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	41261034	102531865	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	total urine protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	46579769	91579769	Rat
11353949	Bp393	Blood pressure QTL 393			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	46579769	91579769	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	46952427	83686153	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	249
Count of miRNA genes:	186
Interacting mature miRNAs:	209
Transcripts:	ENSRNOT00000019880
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium
Low	2	12	12	4	19	4			32	14	31	11
Below cutoff	1	28	36	34		34	5	7	42	20	10		5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133575	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U49066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000019880 ⟹ ENSRNOP00000019880

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	9	47,047,832 - 47,095,831 (+)	Ensembl

RefSeq Acc Id:

NM_133575 ⟹ NP_598259

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	42,591,934 - 42,636,667 (+)	NCBI
Rnor_6.0	9	47,048,915 - 47,093,679 (+)	NCBI
Rnor_5.0	9	46,733,619 - 46,778,352 (+)	NCBI
RGSC_v3.4	9	39,492,187 - 39,537,792 (+)	RGD
Celera	9	40,337,394 - 40,381,411 (+)	RGD

Sequence:

show sequence

CCGGCTGGCCTAGGATCAGGCAAGAAAAGGCTGAACGCCTTTCTAAGGACGGACTCTTTCTGTA
CAGCTCCACTTGGGGAAGCCCGAAATGGGGATGCCACCCTTGCTCTTCTGTTGGGTGTCTTTCG
TGCTTCCACTTTTTGTGGCAGCAGGTAACTGTACTGATGTCTATATGCACCATGAGATGATTTC
AGAGGGCCAGCCTTTCCCCTTCAACTGCACATACCCTCCAGTAACAAACGGGGCAGTGAATCTG
ACATGGCATAGAACACCCAGTAAGAGCCCAATCTCCATCAACAGACACGTTAGAATTCACCAGG
ACCAGTCCTGGATTTTGTTTCTTCCGTTGGCATTGGAGGACTCAGGCATCTATCAATGTGTTAT
AAAGGATGCCCACAGCTGTTACCGAATAGCTATAAACCTAACCGTTTTTAGAAAACACTGGTGC
GACTCTTCCAACGAAGAGAGTTCCATAAATTCCTCAGATGAGTACCAGCAATGGTTACCCATAG
GAAAATCGGGCAGTCTGACGTGCCATCTCTACTTCCCAGAGAGCTGTGTTTTGGATTCAATAAA
GTGGTATAAGGGTTGTGAAGAGATTAAAGTGAGCAAGAAGTTTTGCCCTACAGGAACAAAGCTT
CTTGTTAACAACATCGACGTGGAGGATAGTGGGAGCTATGCATGCTCAGCCAGACTGACACACT
TGGGGAGAATCTTCACGGTTAGAAACTACATTGCTGTGAATACCAAGGAAGTTGGGTCTGGAGG
AAGGATCCCTAACATCACGTATCCAAAAAACAACTCCATTGAAGTTCAACTTGGCTCCACCCTC
ATTGTGGACTGCAATATAACAGACACGAAGGAGAATACGAACCTCAGATGCTGGCGAGTTAACA
ACACCCTGGTGGACGATTACTACAACGACTTCAAACGCATCCAGGAAGGAATCGAAACCAATCT
GTCTCTGAGGAATCACATTCTGTACACAGTGAACATAACATTCTTAGAAGTGAAAATGGAGGAC
TACGGCCATCCTTTCACATGCCACGCTGCGGTGTCCGCAGCCTACATCATTCTGAAACGCCCAG
CTCCAGACTTCCGGGCTTACCTCATAGGAGGTCTCATGGCTTTCCTACTTCTGGCCGTGTCCAT
TCTGTACATCTACAACACCTTTAAGGTCGACATCGTGCTTTGGTATAGGAGTACCTTCCACACT
GCCCAGGCTCCAGATGACGAGAAGCTGTATGATGCCTATGTCTTATACCCCAAGTACCCAAGAG
AAAGCCAGGGCCATGATGTGGACACACTGGTGTTGAAGATCTTGCCCGAGGTGCTGGAGAAACA
GTGTGGATATAAGTTATTCATATTTGGCAGGGATGAATTCCCTGGACAAGCTGTGGCCAGCGTC
ATTGATGAAAACATTAAGCTGTGTAGGAGGCTGATGGTCCTCGTGGCACCAGAGACATCCAGCT
TCAGCTTTCTGAAGAACTTGACTGAAGAACAAATCGCTGTCTACAATGCCCTCGTCCAGGACGG
CATGAAGGTCATTCTGATTGAACTGGAGAGAGTCAAGGACTACAGCACCATGCCCGAGTCCATT
CAGTACATCCGACAGAAGCACGGGGCCATCCAGTGGGATGGGGACTTCACAGAGCAGGCACAGT
GCGCCAAGACGAAATTCTGGAAGAAAGTGAGATATCATATGCCACCCAGGAGGTACCCGGCATC
TCCCCCCGTCCAGCTGCTAGGACACACACCCCGCATACCAGGCTAGTGCAGTGCCACCGCCACG
GGGCTCATAACTCCTTAAGAGCGGTTAGTGTGTGGTGGCTCGCACTACAACCTCTCTGGATCAT
CTACCCCCGTAGCTTGCTCTTTTGTGCTTGTGAGCGACCTCGTCCTTAGCCACGTCATATTTTG
ATTTTTTGTTTGTTTTGTTTGTTTGTTGTATGCTTTTAGTCATAGCTGATTCGTACTACTCCTG
TTTGCTTCATGGTTCCTGAATCCCAGAGACTCCCTGAGCATGGGTGGCTATCATGTTGGG

hide sequence

RefSeq Acc Id:

XM_017596258 ⟹ XP_017451747

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	47,044,870 - 47,093,600 (+)	NCBI

Sequence:

show sequence

TCTAGGAATCATTGCAAATTTGAAAGTCAAAACTGATATCCTTTGAAATGATCATTTCTTTGTC
GGTAAAGTATTACTTAGGAGTGCCTGGGCTTTGGGCCTTTGCTCCAGGTTCACGCCAGCCCTCA
TTAATGGCCAAGTGTGCTGAGATAGGAGCCAGGTCCTCTAACTCCCGGATGACTAGCTCCTCTT
CCCAACCACCCACTTTCTCTAGTTGACATTGATGAGGGATAAATGCAAGTCCATTTAGCTAAGT
TGGAAAATGTGGCCCAGGGTTATCAAGAGTGGGAAAGAATTCAGGGCATTAATGAACAAGCAGA
GTGAATGGCGGTGCTGGGTGGAGCCCACACTTGCTAGCAGTTCCTGGGCCCCGTGATTAGGAGT
CAGTACCACCTGGAGAGTGTCGGGACAGATGGCTCCCTGTTGGCCAGGCTGGAGAGACCAGGAG
ACATCAACTACCAACTACCAGCCCGAAATGGGGATGCCACCCTTGCTCTTCTGTTGGGTGTCTT
TCGTGCTTCCACTTTTTGTGGCAGCAGGTAACTGTACTGATGTCTATATGCACCATGAGATGAT
TTCAGAGGGCCAGCCTTTCCCCTTCAACTGCACATACCCTCCAGTAACAAACGGGGCAGTGAAT
CTGACATGGCATAGAACACCCAGTAAGAGCCCAATCTCCATCAACAGACACGTTAGAATTCACC
AGGACCAGTCCTGGATTTTGTTTCTTCCGTTGGCATTGGAGGACTCAGGCATCTATCAATGTGT
TATAAAGGATGCCCACAGCTGTTACCGAATAGCTATAAACCTAACCGTTTTTAGAAAACACTGG
TGCGACTCTTCCAACGAAGAGAGTTCCATAAATTCCTCAGATGAGTACCAGCAATGGTTACCCA
TAGGAAAATCGGGCAGTCTGACGTGCCATCTCTACTTCCCAGAGAGCTGTGTTTTGGATTCAAT
AAAGTGGTATAAGGGTTGTGAAGAGATTAAAGTGAGCAAGAAGTTTTGCCCTACAGGAACAAAG
CTTCTTGTTAACAACATCGACGTGGAGGATAGTGGGAGCTATGCATGCTCAGCCAGACTGACAC
ACTTGGGGAGAATCTTCACGGTTAGAAACTACATTGCTGTGAATACCAAGGAAGTTGGGTCTGG
AGGAAGGATCCCTAACATCACGTATCCAAAAAACAACTCCATTGAAGTTCAACTTGGCTCCACC
CTCATTGTGGACTGCAATATAACAGACACGAAGGAGAATACGAACCTCAGATGCTGGCGAGTTA
ACAACACCCTGGTGGACGATTACTACAACGACTCCAAACGCATCCAGGAAGGAATCGAAACCAA
TCTGTCTCTGAGGAATCACATTCTGTACACAGTGAACATAACATTCTTAGAAGTGAAAATGGAG
GACTACGGCCATCCTTTCACATGCCACGCTGGCGTGTCCGCAGCCTACATCATTCTGAAACGCC
CAGCTCCAGACTTCCGGGCTTACCTCATAGGAGGTCTCATGGCTTTCCTACTTCTGGCCGTGTC
CATTCTGTACATCTACAACACCTTTAAGGTCGACATCGTGCTTTGGTATAGGAGTACCTTCCAC
ACTGCCCAGGCTCCAGATGACGAGAAGCTGTATGATGCCTATGTCTTATACCCCAAGTACCCAA
GAGAAAGCCAGGGCCATGATGTGGACACACTGGTGTTGAAGATCTTGCCCGAGGTGCTGGAGAA
ACAGTGTGGATATAAGTTATTCATATTTGGCAGGGATGAATTCCCTGGACAAGCTGTGGCCAGC
GTCATTGATGAAAACATTAAGCTGTGTAGGAGGCTGATGGTCCTCGTGGCACCAGAGACATCCA
GCTTCAGCTTTCTGAAGAACTTGACTGAAGAACAAATCGCTGTCTACAATGCCCTCGTCCAGGA
CGGCATGAAGGTCATTCTGATTGAACTGGAGAGAGTCAAGGACTACAGCACCATGCCCGAGTCC
ATTCAGTACATCCGACAGAAGCACGGGGCCATCCAGTGGGATGGGGACTTCACAGAGCAGGCAC
AGTGCGCCAAGACGAAATTCTGGAAGAAAGTGAGATATCATATGCCACCCAGGAGGTACCCGGC
ATCTCCCCCCGTCCAGCTGCTAGGACACACACCCCGCATACCAGGCTAGTGCAGTGCCACCGCC
ACGGGGCTCATAACTCCTTAAGAGCGGTTAGTGTGTGGTGGCTCGCACTACAACCTCTCTGGAT
CATCTACCCCCGTAGCTTGCTCTTTTGTGCTTGTGAGCGACCTCGTCCTTAGCCACGTCATATT
TTGATTTTTTGTTTGTTTTGTTTGTTTGTTGTATGCTTTTAGTCATAGCT

hide sequence

RefSeq Acc Id:

XM_017596259 ⟹ XP_017451748

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	42,591,658 - 42,639,351 (+)	NCBI
Rnor_6.0	9	47,048,447 - 47,093,600 (+)	NCBI

Sequence:

show sequence

TCAAGGGACAGTGCCCGGACAGACACCTATCCATCTTAACTTTGTGAACTTGGGACAGCTAGTC
AGACTGGCCCTGTGGTTGTTTAGAAAGTCTTACAGTTTCTAATCCACAAAGACCACCAGGAAGG
CCCACTTAGAAGCTGCTGGTCTGATGGCATTTGCTATCTCTGCACTTCCTAGTGCCCAGTGGGG
TTTCCCGTGTCTCTGGGGCAGGAAGACAGGTCCGGGCTAGCATCGCTTTATGGCAAGTTTAAAC
TGCAGCATTCAACCTGTCGGGAGTCCGCTTTACTGAAGATCTAGAGGGTTAATCCTAAACCATG
TGGAATGGCTTCCACATCTGGAATAGTCCATATTAGGGCAATGCTGGGCATGTTAAGAACCGCT
CAAACAGTGCTTGGAAAGAAATGATAATTTTTTTTAGCGATGATCTGGGGCATATTTAAGCCGA
CATTCCTGCTAGATGAACGTGCTGGCCTAGGATCAGGCAAGAAAAGGCTGAACGCCTTTCTAAG
GACGGACTCTTTCTGTACAGCTCCACTTGGGGAAGGTGAGTCTGCCCCGCCCGTGGCGGAGAGG
CGATGCCCAGGCTGCTGAATCCGGTCCCTGGCGTGGTTCCAGCTCTGCTCTAGGAGACCCGGCG
CTCTGAGACCTCATAGACAGCCCGAAATGGGGATGCCACCCTTGCTCTTCTGTTGGGTGTCTTT
CGTGCTTCCACTTTTTGTGGCAGCAGGTAACTGTACTGATGTCTATATGCACCATGAGATGATT
TCAGAGGGCCAGCCTTTCCCCTTCAACTGCACATACCCTCCAGTAACAAACGGGGCAGTGAATC
TGACATGGCATAGAACACCCAGTAAGAGCCCAATCTCCATCAACAGACACGTTAGAATTCACCA
GGACCAGTCCTGGATTTTGTTTCTTCCGTTGGCATTGGAGGACTCAGGCATCTATCAATGTGTT
ATAAAGGATGCCCACAGCTGTTACCGAATAGCTATAAACCTAACCGTTTTTAGAAAACACTGGT
GCGACTCTTCCAACGAAGAGAGTTCCATAAATTCCTCAGATGAGTACCAGCAATGGTTACCCAT
AGGAAAATCGGGCAGTCTGACGTGCCATCTCTACTTCCCAGAGAGCTGTGTTTTGGATTCAATA
AAGTGGTATAAGGGTTGTGAAGAGATTAAAGTGAGCAAGAAGTTTTGCCCTACAGGAACAAAGC
TTCTTGTTAACAACATCGACGTGGAGGATAGTGGGAGCTATGCATGCTCAGCCAGACTGACACA
CTTGGGGAGAATCTTCACGGTTAGAAACTACATTGCTGTGAATACCAAGGAAGTTGGGTCTGGA
GGAAGGATCCCTAACATCACGTATCCAAAAAACAACTCCATTGAAGTTCAACTTGGCTCCACCC
TCATTGTGGACTGCAATATAACAGACACGAAGGAGAATACGAACCTCAGATGCTGGCGAGTTAA
CAACACCCTGGTGGACGATTACTACAACGACTCCAAACGCATCCAGGAAGGAATCGAAACCAAT
CTGTCTCTGAGGAATCACATTCTGTACACAGTGAACATAACATTCTTAGAAGTGAAAATGGAGG
ACTACGGCCATCCTTTCACATGCCACGCTGGCGTGTCCGCAGCCTACATCATTCTGAAACGCCC
AGCTCCAGACTTCCGGGCTTACCTCATAGGAGGTCTCATGGCTTTCCTACTTCTGGCCGTGTCC
ATTCTGTACATCTACAACACCTTTAAGGTCGACATCGTGCTTTGGTATAGGAGTACCTTCCACA
CTGCCCAGGCTCCAGATGACGAGAAGCTGTATGATGCCTATGTCTTATACCCCAAGTACCCAAG
AGAAAGCCAGGGCCATGATGTGGACACACTGGTGTTGAAGATCTTGCCCGAGGTGCTGGAGAAA
CAGTGTGGATATAAGTTATTCATATTTGGCAGGGATGAATTCCCTGGACAAGCTGTGGCCAGCG
TCATTGATGAAAACATTAAGCTGTGTAGGAGGCTGATGGTCCTCGTGGCACCAGAGACATCCAG
CTTCAGCTTTCTGAAGAACTTGACTGAAGAACAAATCGCTGTCTACAATGCCCTCGTCCAGGAC
GGCATGAAGGTCATTCTGATTGAACTGGAGAGAGTCAAGGACTACAGCACCATGCCCGAGTCCA
TTCAGTACATCCGACAGAAGCACGGGGCCATCCAGTGGGATGGGGACTTCACAGAGCAGGCACA
GTGCGCCAAGACGAAATTCTGGAAGAAAGTGAGATATCATATGCCACCCAGGAGGTACCCGGCA
TCTCCCCCCGTCCAGCTGCTAGGACACACACCCCGCATACCAGGCTAGTGCAGTGCCACCGCCA
CGGGGCTCATAACTCCTTAAGAGCGGTTAGTGTGTGGTGGCTCGCACTACAACCTCTCTGGATC
ATCTACCCCCGTAGCTTGCTCTTTTGTGCTTGTGAGCGACCTCGTCCTTAGCCACGTCATATTT
TGATTTTTTGTTTGTTTTGTTTGTTTGTTGTATGCTTTTAGTCATAGCT

hide sequence

RefSeq Acc Id:

XM_017596260 ⟹ XP_017451749

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	47,047,768 - 47,093,600 (+)	NCBI

Sequence:

show sequence

GTTTAAGACTGGGAGTTTGGGTATAGGCGGACAGACACGGGAAGCCAGGAGAAGATTCCTTCTG
ATGTTTGTTGCTTACGTGACATAGTTTGTTTGGAATTATGTAGCCCTTGACAACTGTGTGGCAT
GCACTTAAAGATACGAAAGTGAGAAGGAGAGGGGTTCACGCAAGGAAAATGAAGTCATTAAGTT
TCTACCAAAGCAGGGTTTCTTCTGGCTACTCCAAACAAAGCTAAAATTGTCCTACGGACCTCTC
TCTCCACTTGGGGAAGGTGAGTCTGCCCCGCCCGTGGCGGAGAGGCGATGCCCAGGCTGCTGAA
TCCGGTCCCTGGCGTGGTTCCAGCTCTGCTCTAGGAGACCCGGCGCTCTGAGACCTCATAGACA
GCCCGAAATGGGGATGCCACCCTTGCTCTTCTGTTGGGTGTCTTTCGTGCTTCCACTTTTTGTG
GCAGCAGGTAACTGTACTGATGTCTATATGCACCATGAGATGATTTCAGAGGGCCAGCCTTTCC
CCTTCAACTGCACATACCCTCCAGTAACAAACGGGGCAGTGAATCTGACATGGCATAGAACACC
CAGTAAGAGCCCAATCTCCATCAACAGACACGTTAGAATTCACCAGGACCAGTCCTGGATTTTG
TTTCTTCCGTTGGCATTGGAGGACTCAGGCATCTATCAATGTGTTATAAAGGATGCCCACAGCT
GTTACCGAATAGCTATAAACCTAACCGTTTTTAGAAAACACTGGTGCGACTCTTCCAACGAAGA
GAGTTCCATAAATTCCTCAGATGAGTACCAGCAATGGTTACCCATAGGAAAATCGGGCAGTCTG
ACGTGCCATCTCTACTTCCCAGAGAGCTGTGTTTTGGATTCAATAAAGTGGTATAAGGGTTGTG
AAGAGATTAAAGTGAGCAAGAAGTTTTGCCCTACAGGAACAAAGCTTCTTGTTAACAACATCGA
CGTGGAGGATAGTGGGAGCTATGCATGCTCAGCCAGACTGACACACTTGGGGAGAATCTTCACG
GTTAGAAACTACATTGCTGTGAATACCAAGGAAGTTGGGTCTGGAGGAAGGATCCCTAACATCA
CGTATCCAAAAAACAACTCCATTGAAGTTCAACTTGGCTCCACCCTCATTGTGGACTGCAATAT
AACAGACACGAAGGAGAATACGAACCTCAGATGCTGGCGAGTTAACAACACCCTGGTGGACGAT
TACTACAACGACTCCAAACGCATCCAGGAAGGAATCGAAACCAATCTGTCTCTGAGGAATCACA
TTCTGTACACAGTGAACATAACATTCTTAGAAGTGAAAATGGAGGACTACGGCCATCCTTTCAC
ATGCCACGCTGGCGTGTCCGCAGCCTACATCATTCTGAAACGCCCAGCTCCAGACTTCCGGGCT
TACCTCATAGGAGGTCTCATGGCTTTCCTACTTCTGGCCGTGTCCATTCTGTACATCTACAACA
CCTTTAAGGTCGACATCGTGCTTTGGTATAGGAGTACCTTCCACACTGCCCAGGCTCCAGATGA
CGAGAAGCTGTATGATGCCTATGTCTTATACCCCAAGTACCCAAGAGAAAGCCAGGGCCATGAT
GTGGACACACTGGTGTTGAAGATCTTGCCCGAGGTGCTGGAGAAACAGTGTGGATATAAGTTAT
TCATATTTGGCAGGGATGAATTCCCTGGACAAGCTGTGGCCAGCGTCATTGATGAAAACATTAA
GCTGTGTAGGAGGCTGATGGTCCTCGTGGCACCAGAGACATCCAGCTTCAGCTTTCTGAAGAAC
TTGACTGAAGAACAAATCGCTGTCTACAATGCCCTCGTCCAGGACGGCATGAAGGTCATTCTGA
TTGAACTGGAGAGAGTCAAGGACTACAGCACCATGCCCGAGTCCATTCAGTACATCCGACAGAA
GCACGGGGCCATCCAGTGGGATGGGGACTTCACAGAGCAGGCACAGTGCGCCAAGACGAAATTC
TGGAAGAAAGTGAGATATCATATGCCACCCAGGAGGTACCCGGCATCTCCCCCCGTCCAGCTGC
TAGGACACACACCCCGCATACCAGGCTAGTGCAGTGCCACCGCCACGGGGCTCATAACTCCTTA
AGAGCGGTTAGTGTGTGGTGGCTCGCACTACAACCTCTCTGGATCATCTACCCCCGTAGCTTGC
TCTTTTGTGCTTGTGAGCGACCTCGTCCTTAGCCACGTCATATTTTGATTTTTTGTTTGTTTTG
TTTGTTTGTTGTATGCTTTTAGTCATAGCT

hide sequence

Protein Sequences


Protein RefSeqs	NP_598259	(Get FASTA)	NCBI Sequence Viewer
	XP_017451748	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB53238	(Get FASTA)	NCBI Sequence Viewer
	EDL99176	(Get FASTA)	NCBI Sequence Viewer
	EDL99177	(Get FASTA)	NCBI Sequence Viewer
	Q62929	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_598259 ⟸ NM_133575

- Peptide Label:

precursor

- Sequence:

show sequence

MGMPPLLFCWVSFVLPLFVAAGNCTDVYMHHEMISEGQPFPFNCTYPPVTNGAVNLTWHRTPSK
SPISINRHVRIHQDQSWILFLPLALEDSGIYQCVIKDAHSCYRIAINLTVFRKHWCDSSNEESS
INSSDEYQQWLPIGKSGSLTCHLYFPESCVLDSIKWYKGCEEIKVSKKFCPTGTKLLVNNIDVE
DSGSYACSARLTHLGRIFTVRNYIAVNTKEVGSGGRIPNITYPKNNSIEVQLGSTLIVDCNITD
TKENTNLRCWRVNNTLVDDYYNDFKRIQEGIETNLSLRNHILYTVNITFLEVKMEDYGHPFTCH
AAVSAAYIILKRPAPDFRAYLIGGLMAFLLLAVSILYIYNTFKVDIVLWYRSTFHTAQAPDDEK
LYDAYVLYPKYPRESQGHDVDTLVLKILPEVLEKQCGYKLFIFGRDEFPGQAVASVIDENIKLC
RRLMVLVAPETSSFSFLKNLTEEQIAVYNALVQDGMKVILIELERVKDYSTMPESIQYIRQKHG
AIQWDGDFTEQAQCAKTKFWKKVRYHMPPRRYPASPPVQLLGHTPRIPG

hide sequence

RefSeq Acc Id:

XP_017451747 ⟸ XM_017596258

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAPCWPGWRDQETSTTNYQPEMGMPPLLFCWVSFVLPLFVAAGNCTDVYMHHEMISEGQPFPFN
CTYPPVTNGAVNLTWHRTPSKSPISINRHVRIHQDQSWILFLPLALEDSGIYQCVIKDAHSCYR
IAINLTVFRKHWCDSSNEESSINSSDEYQQWLPIGKSGSLTCHLYFPESCVLDSIKWYKGCEEI
KVSKKFCPTGTKLLVNNIDVEDSGSYACSARLTHLGRIFTVRNYIAVNTKEVGSGGRIPNITYP
KNNSIEVQLGSTLIVDCNITDTKENTNLRCWRVNNTLVDDYYNDSKRIQEGIETNLSLRNHILY
TVNITFLEVKMEDYGHPFTCHAGVSAAYIILKRPAPDFRAYLIGGLMAFLLLAVSILYIYNTFK
VDIVLWYRSTFHTAQAPDDEKLYDAYVLYPKYPRESQGHDVDTLVLKILPEVLEKQCGYKLFIF
GRDEFPGQAVASVIDENIKLCRRLMVLVAPETSSFSFLKNLTEEQIAVYNALVQDGMKVILIEL
ERVKDYSTMPESIQYIRQKHGAIQWDGDFTEQAQCAKTKFWKKVRYHMPPRRYPASPPVQLLGH
TPRIPG

hide sequence

RefSeq Acc Id:

XP_017451749 ⟸ XM_017596260

- Peptide Label:

isoform X2

- Sequence:

show sequence

MGMPPLLFCWVSFVLPLFVAAGNCTDVYMHHEMISEGQPFPFNCTYPPVTNGAVNLTWHRTPSK
SPISINRHVRIHQDQSWILFLPLALEDSGIYQCVIKDAHSCYRIAINLTVFRKHWCDSSNEESS
INSSDEYQQWLPIGKSGSLTCHLYFPESCVLDSIKWYKGCEEIKVSKKFCPTGTKLLVNNIDVE
DSGSYACSARLTHLGRIFTVRNYIAVNTKEVGSGGRIPNITYPKNNSIEVQLGSTLIVDCNITD
TKENTNLRCWRVNNTLVDDYYNDSKRIQEGIETNLSLRNHILYTVNITFLEVKMEDYGHPFTCH
AGVSAAYIILKRPAPDFRAYLIGGLMAFLLLAVSILYIYNTFKVDIVLWYRSTFHTAQAPDDEK
LYDAYVLYPKYPRESQGHDVDTLVLKILPEVLEKQCGYKLFIFGRDEFPGQAVASVIDENIKLC
RRLMVLVAPETSSFSFLKNLTEEQIAVYNALVQDGMKVILIELERVKDYSTMPESIQYIRQKHG
AIQWDGDFTEQAQCAKTKFWKKVRYHMPPRRYPASPPVQLLGHTPRIPG

hide sequence

RefSeq Acc Id:	XP_017451748 ⟸ XM_017596259
- Peptide Label:	isoform X1
- UniProtKB:	G3V7W4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGMPPLLFCWVSFVLPLFVAAGNCTDVYMHHEMISEGQPFPFNCTYPPVTNGAVNLTWHRTPSK SPISINRHVRIHQDQSWILFLPLALEDSGIYQCVIKDAHSCYRIAINLTVFRKHWCDSSNEESS INSSDEYQQWLPIGKSGSLTCHLYFPESCVLDSIKWYKGCEEIKVSKKFCPTGTKLLVNNIDVE DSGSYACSARLTHLGRIFTVRNYIAVNTKEVGSGGRIPNITYPKNNSIEVQLGSTLIVDCNITD TKENTNLRCWRVNNTLVDDYYNDSKRIQEGIETNLSLRNHILYTVNITFLEVKMEDYGHPFTCH AGVSAAYIILKRPAPDFRAYLIGGLMAFLLLAVSILYIYNTFKVDIVLWYRSTFHTAQAPDDEK LYDAYVLYPKYPRESQGHDVDTLVLKILPEVLEKQCGYKLFIFGRDEFPGQAVASVIDENIKLC RRLMVLVAPETSSFSFLKNLTEEQIAVYNALVQDGMKVILIELERVKDYSTMPESIQYIRQKHG AIQWDGDFTEQAQCAKTKFWKKVRYHMPPRRYPASPPVQLLGHTPRIPG hide sequence

RefSeq Acc Id:

ENSRNOP00000019880 ⟸ ENSRNOT00000019880

Protein Domains

Ig-like Ig-like C2-type TIR

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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CSV

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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CSV

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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CSV

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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CSV

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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CSV

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621782	AgrOrtholog
Ensembl Genes	ENSRNOG00000014683	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000019880	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000019880	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.40.50.10140	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL-1_rcpt_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL-1_rcpt_I/II-typ	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TIR_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Toll_tir_struct_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:171106	UniProtKB/Swiss-Prot
NCBI Gene	171106	ENTREZGENE
PANTHER	PTHR11890	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Ig_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TIR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Il1rl2	PhenoGen
PRINTS	INTRLKN1R12F	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TIR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	IGc2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SM00409	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TIR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF52200	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	G3V7W4	ENTREZGENE, UniProtKB/TrEMBL
	ILRL2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Il1rl2	interleukin 1 receptor-like 2			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Il1rl2	interleukin 1 receptor-like 2			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in lung and epididymis with lower levels of expression detected in the testis and cerebral cortex	729063
gene_function	did not bind either [125I]-recombinant human IL 1 alpha or [125I]-recombinant human IL 1 beta with high affinity	729063

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)