IL1RL2 (interleukin 1 receptor like 2) - Rat Genome Database

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Gene: IL1RL2 (interleukin 1 receptor like 2) Homo sapiens
Analyze
Symbol: IL1RL2
Name: interleukin 1 receptor like 2
RGD ID: 1353187
HGNC Page HGNC:5999
Description: Predicted to enable interleukin-1 receptor activity. Predicted to be involved in regulation of inflammatory response. Predicted to act upstream of or within positive regulation of T cell differentiation and positive regulation of interleukin-6 production. Predicted to be located in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: IL-1 receptor-related protein 2; IL-1Rrp2; IL-36 receptor; IL-36R; IL1R-rp2; IL1RRP2; interleukin 1 receptor-like 2; interleukin-1 receptor-like 2; interleukin-1 receptor-related protein 2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382102,186,973 - 102,243,086 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2102,187,006 - 102,240,002 (+)EnsemblGRCh38hg38GRCh38
GRCh372102,803,433 - 102,856,462 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362102,169,865 - 102,222,243 (+)NCBINCBI36Build 36hg18NCBI36
Build 342102,261,950 - 102,314,329NCBI
Celera297,004,649 - 97,057,020 (+)NCBICelera
Cytogenetic Map2q12.1NCBI
HuRef296,567,290 - 96,619,802 (+)NCBIHuRef
CHM1_12102,807,775 - 102,860,073 (+)NCBICHM1_1
T2T-CHM13v2.02102,645,259 - 102,701,349 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL 1R-rp2). Lovenberg TW, etal., J Neuroimmunol 1996 Nov;70(2):113-22.
3. Deficiency of Interleukin-36 Receptor Protected Cardiomyocytes from Ischemia-Reperfusion Injury in Cardiopulmonary Bypass. Luo C, etal., Med Sci Monit. 2020 Feb 12;26:e918933. doi: 10.12659/MSM.918933.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1833184   PMID:8332913   PMID:9325300   PMID:10191101   PMID:10882729   PMID:11466363   PMID:12477932   PMID:16546408   PMID:19074885   PMID:19180518   PMID:19684156   PMID:19773279  
PMID:20190752   PMID:20237496   PMID:20353565   PMID:20800603   PMID:20959797   PMID:21860022   PMID:21873635   PMID:22144259   PMID:22315422   PMID:23128233   PMID:23817569   PMID:23966867  
PMID:23999434   PMID:25902739   PMID:26269592   PMID:26813344   PMID:27269181   PMID:27307043   PMID:27673278   PMID:27853811   PMID:28514442   PMID:29176319   PMID:29987050   PMID:33034926  
PMID:33961781   PMID:35171706   PMID:35256949   PMID:36482185   PMID:36525507   PMID:37414245   PMID:38189700  


Genomics

Comparative Map Data
IL1RL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382102,186,973 - 102,243,086 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2102,187,006 - 102,240,002 (+)EnsemblGRCh38hg38GRCh38
GRCh372102,803,433 - 102,856,462 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362102,169,865 - 102,222,243 (+)NCBINCBI36Build 36hg18NCBI36
Build 342102,261,950 - 102,314,329NCBI
Celera297,004,649 - 97,057,020 (+)NCBICelera
Cytogenetic Map2q12.1NCBI
HuRef296,567,290 - 96,619,802 (+)NCBIHuRef
CHM1_12102,807,775 - 102,860,073 (+)NCBICHM1_1
T2T-CHM13v2.02102,645,259 - 102,701,349 (+)NCBIT2T-CHM13v2.0
Il1rl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39140,363,697 - 40,406,722 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl140,363,770 - 40,406,722 (+)EnsemblGRCm39 Ensembl
GRCm38140,324,589 - 40,367,555 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl140,324,610 - 40,367,562 (+)EnsemblGRCm38mm10GRCm38
MGSCv37140,381,472 - 40,422,316 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36140,269,173 - 40,310,017 (+)NCBIMGSCv36mm8
Celera140,135,784 - 40,176,671 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map118.96NCBI
Il1rl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8950,087,271 - 50,134,225 (+)NCBIGRCr8
mRatBN7.2942,591,658 - 42,639,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl942,591,934 - 42,636,667 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx951,094,273 - 51,139,209 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0956,216,970 - 56,261,896 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0954,492,602 - 54,537,352 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0947,044,870 - 47,093,679 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl947,047,832 - 47,095,831 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0946,733,619 - 46,778,352 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4939,492,187 - 39,537,792 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1939,493,600 - 39,539,206 (+)NCBI
Celera940,337,394 - 40,381,411 (+)NCBICelera
Cytogenetic Map9q22NCBI
Il1rl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554707,704,134 - 7,742,064 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554707,703,369 - 7,742,058 (+)NCBIChiLan1.0ChiLan1.0
IL1RL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21225,995,088 - 26,049,489 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A25,997,849 - 26,051,650 (-)NCBINHGRI_mPanPan1
PanPan1.12A103,237,107 - 103,289,427 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A103,237,996 - 103,289,414 (+)Ensemblpanpan1.1panPan2
IL1RL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11040,776,670 - 40,817,263 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1040,778,590 - 40,816,044 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1040,698,936 - 40,742,868 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01041,639,600 - 41,683,546 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1041,645,070 - 41,682,534 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11041,353,871 - 41,397,328 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01041,635,603 - 41,679,766 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01041,827,554 - 41,871,492 (-)NCBIUU_Cfam_GSD_1.0
Il1rl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629290,201,299 - 90,240,726 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936713893,769 - 930,889 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936713893,020 - 932,406 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL1RL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl351,966,691 - 52,011,479 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1351,978,857 - 52,011,607 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2354,382,183 - 54,396,574 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL1RL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1145,862,140 - 5,912,789 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl145,863,727 - 5,915,370 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041173,542,157 - 173,595,405 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il1rl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247496,749,007 - 6,779,753 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247496,747,131 - 6,781,908 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IL1RL2
37 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q11.2-12.3(chr2:100378510-108472871)x3 copy number gain See cases [RCV000050836] Chr2:100378510..108472871 [GRCh38]
Chr2:100994972..109089327 [GRCh37]
Chr2:100361404..108455759 [NCBI36]
Chr2:2q11.2-12.3
pathogenic
GRCh38/hg38 2q11.1-12.1(chr2:94817406-103252396)x3 copy number gain See cases [RCV000052946] Chr2:94817406..103252396 [GRCh38]
Chr2:95618109..103868854 [GRCh37]
Chr2:94846878..103235286 [NCBI36]
Chr2:2q11.1-12.1
pathogenic
GRCh38/hg38 2q11.2-13(chr2:97672522-110211318)x3 copy number gain See cases [RCV000052947] Chr2:97672522..110211318 [GRCh38]
Chr2:98288985..110968895 [GRCh37]
Chr2:97655417..110326184 [NCBI36]
Chr2:2q11.2-13
pathogenic
GRCh38/hg38 2p11.2-q11.2(chr2:91443218-102334856)x3 copy number gain See cases [RCV000052945] Chr2:91443218..102334856 [GRCh38]
Chr2:91617683..102951316 [GRCh37]
Chr2:90981410..102317748 [NCBI36]
Chr2:2p11.2-q11.2
pathogenic
NM_003854.2(IL1RL2):c.133C>T (p.Pro45Ser) single nucleotide variant Malignant melanoma [RCV000064985] Chr2:102189150 [GRCh38]
Chr2:102805610 [GRCh37]
Chr2:102172042 [NCBI36]
Chr2:2q12.1
not provided
NM_003854.2(IL1RL2):c.733C>T (p.Leu245=) single nucleotide variant Malignant melanoma [RCV000064986] Chr2:102218961 [GRCh38]
Chr2:102835421 [GRCh37]
Chr2:102201853 [NCBI36]
Chr2:2q12.1
not provided
NM_003854.2(IL1RL2):c.938C>T (p.Pro313Leu) single nucleotide variant Malignant melanoma [RCV000064987] Chr2:102219964 [GRCh38]
Chr2:102836424 [GRCh37]
Chr2:102202856 [NCBI36]
Chr2:2q12.1
not provided
GRCh38/hg38 2q11.2-12.2(chr2:102084275-106085903)x1 copy number loss See cases [RCV000134974] Chr2:102084275..106085903 [GRCh38]
Chr2:102700735..106702359 [GRCh37]
Chr2:102067167..106068791 [NCBI36]
Chr2:2q11.2-12.2
likely pathogenic
GRCh38/hg38 2q11.2-13(chr2:101710825-110791418)x3 copy number gain See cases [RCV000138645] Chr2:101710825..110791418 [GRCh38]
Chr2:102327287..111548995 [GRCh37]
Chr2:101693719..111265466 [NCBI36]
Chr2:2q11.2-13
pathogenic
GRCh38/hg38 2q11.1-13(chr2:94678532-110602409)x3 copy number gain See cases [RCV000141075] Chr2:94678532..110602409 [GRCh38]
Chr2:95344257..111359986 [GRCh37]
Chr2:94707984..111076455 [NCBI36]
Chr2:2q11.1-13
pathogenic
GRCh38/hg38 2q11.2-12.2(chr2:100478285-106498909)x3 copy number gain See cases [RCV000141445] Chr2:100478285..106498909 [GRCh38]
Chr2:101094747..107115365 [GRCh37]
Chr2:100461179..106481797 [NCBI36]
Chr2:2q11.2-12.2
uncertain significance
GRCh38/hg38 2q11.2-12.2(chr2:101234070-105679157)x1 copy number loss See cases [RCV000142969] Chr2:101234070..105679157 [GRCh38]
Chr2:101850532..106295614 [GRCh37]
Chr2:101216964..105662046 [NCBI36]
Chr2:2q11.2-12.2
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2q11.1-12.3(chr2:95529039-108518266) copy number gain See cases [RCV000449270] Chr2:95529039..108518266 [GRCh37]
Chr2:2q11.1-12.3
pathogenic
GRCh37/hg19 2q11.1-13(chr2:95327499-111370025)x4 copy number gain See cases [RCV000446842] Chr2:95327499..111370025 [GRCh37]
Chr2:2q11.1-13
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
GRCh37/hg19 2q11.1-12.2(chr2:95518497-107186127) copy number gain See cases [RCV000511158] Chr2:95518497..107186127 [GRCh37]
Chr2:2q11.1-12.2
uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
NM_003854.4(IL1RL2):c.365T>C (p.Ile122Thr) single nucleotide variant Inborn genetic diseases [RCV003254932] Chr2:102191996 [GRCh38]
Chr2:102808456 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.257A>T (p.Glu86Val) single nucleotide variant Inborn genetic diseases [RCV003262828] Chr2:102189274 [GRCh38]
Chr2:102805734 [GRCh37]
Chr2:2q12.1
uncertain significance
Single allele deletion not provided [RCV000714264] Chr2:40608411..146900718 [GRCh37]
Chr2:2p22.1-q22.3
likely pathogenic
GRCh37/hg19 2q11.1-13(chr2:96353030-114045463)x3 copy number gain not provided [RCV000682168] Chr2:96353030..114045463 [GRCh37]
Chr2:2q11.1-13
pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
NM_003854.4(IL1RL2):c.710T>C (p.Ile237Thr) single nucleotide variant not provided [RCV000969441] Chr2:102212160 [GRCh38]
Chr2:102828620 [GRCh37]
Chr2:2q12.1
benign
NM_003854.4(IL1RL2):c.1665C>T (p.Cys555=) single nucleotide variant not provided [RCV000880062] Chr2:102235264 [GRCh38]
Chr2:102851724 [GRCh37]
Chr2:2q12.1
likely benign
NM_003854.4(IL1RL2):c.1054G>A (p.Val352Ile) single nucleotide variant not provided [RCV000968545] Chr2:102225960 [GRCh38]
Chr2:102842420 [GRCh37]
Chr2:2q12.1
benign
GRCh37/hg19 2q11.2-12.1(chr2:102248064-103361749)x3 copy number gain not provided [RCV000848462] Chr2:102248064..103361749 [GRCh37]
Chr2:2q11.2-12.1
uncertain significance
NM_003854.4(IL1RL2):c.-12-281C>A single nucleotide variant Ascending aortic dissection [RCV001543147] Chr2:102187575 [GRCh38]
Chr2:102804035 [GRCh37]
Chr2:2q12.1
association
NM_003854.4(IL1RL2):c.1678+1065T>C single nucleotide variant Ascending aortic dissection [RCV001543153] Chr2:102236342 [GRCh38]
Chr2:102852802 [GRCh37]
Chr2:2q12.1
association
NM_003854.4(IL1RL2):c.1611G>T (p.Pro537=) single nucleotide variant not provided [RCV000912305] Chr2:102235210 [GRCh38]
Chr2:102851670 [GRCh37]
Chr2:2q12.1
likely benign
GRCh37/hg19 2q11.2-12.1(chr2:102579520-103179707)x1 copy number loss not provided [RCV002472759] Chr2:102579520..103179707 [GRCh37]
Chr2:2q11.2-12.1
uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3
pathogenic
NM_003854.4(IL1RL2):c.1610C>T (p.Pro537Leu) single nucleotide variant Inborn genetic diseases [RCV003253990] Chr2:102235209 [GRCh38]
Chr2:102851669 [GRCh37]
Chr2:2q12.1
uncertain significance
GRCh37/hg19 2q11.2-12.2(chr2:101699537-106383710)x1 copy number loss not provided [RCV001827686] Chr2:101699537..106383710 [GRCh37]
Chr2:2q11.2-12.2
uncertain significance
GRCh37/hg19 2p25.1-q13(chr2:11504318-111365996)x1 copy number loss See cases [RCV002287563] Chr2:11504318..111365996 [GRCh37]
Chr2:2p25.1-q13
pathogenic
NM_003854.4(IL1RL2):c.1021G>A (p.Gly341Arg) single nucleotide variant Inborn genetic diseases [RCV002753205] Chr2:102225927 [GRCh38]
Chr2:102842387 [GRCh37]
Chr2:2q12.1
uncertain significance
GRCh37/hg19 2q11.2-12.1(chr2:102443532-105019078)x1 copy number loss not provided [RCV002475606] Chr2:102443532..105019078 [GRCh37]
Chr2:2q11.2-12.1
uncertain significance
NM_003854.4(IL1RL2):c.125G>A (p.Cys42Tyr) single nucleotide variant Inborn genetic diseases [RCV002905712] Chr2:102189142 [GRCh38]
Chr2:102805602 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.1298C>T (p.Ala433Val) single nucleotide variant Inborn genetic diseases [RCV002659853] Chr2:102234897 [GRCh38]
Chr2:102851357 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.846A>C (p.Glu282Asp) single nucleotide variant Inborn genetic diseases [RCV002758313] Chr2:102219074 [GRCh38]
Chr2:102835534 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.919A>T (p.Met307Leu) single nucleotide variant Inborn genetic diseases [RCV002998348] Chr2:102219945 [GRCh38]
Chr2:102836405 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.921G>T (p.Met307Ile) single nucleotide variant Inborn genetic diseases [RCV002661070] Chr2:102219947 [GRCh38]
Chr2:102836407 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.1069A>C (p.Asn357His) single nucleotide variant Inborn genetic diseases [RCV002712856] Chr2:102225975 [GRCh38]
Chr2:102842435 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.1354G>T (p.Val452Leu) single nucleotide variant Inborn genetic diseases [RCV002664383] Chr2:102234953 [GRCh38]
Chr2:102851413 [GRCh37]
Chr2:2q12.1
likely benign
NM_003854.4(IL1RL2):c.904T>C (p.Phe302Leu) single nucleotide variant Inborn genetic diseases [RCV002916067] Chr2:102219930 [GRCh38]
Chr2:102836390 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.1324G>A (p.Val442Ile) single nucleotide variant Inborn genetic diseases [RCV002673422] Chr2:102234923 [GRCh38]
Chr2:102851383 [GRCh37]
Chr2:2q12.1
likely benign
NM_003854.4(IL1RL2):c.995C>T (p.Pro332Leu) single nucleotide variant Inborn genetic diseases [RCV002944835] Chr2:102225901 [GRCh38]
Chr2:102842361 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.1529C>T (p.Ala510Val) single nucleotide variant Inborn genetic diseases [RCV002656417] Chr2:102235128 [GRCh38]
Chr2:102851588 [GRCh37]
Chr2:2q12.1
likely benign
NM_003854.4(IL1RL2):c.1479C>G (p.Asp493Glu) single nucleotide variant Inborn genetic diseases [RCV003202689] Chr2:102235078 [GRCh38]
Chr2:102851538 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.86A>T (p.Asn29Ile) single nucleotide variant Inborn genetic diseases [RCV003219467] Chr2:102189103 [GRCh38]
Chr2:102805563 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.1553C>G (p.Thr518Arg) single nucleotide variant Inborn genetic diseases [RCV003286606] Chr2:102235152 [GRCh38]
Chr2:102851612 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.253A>G (p.Met85Val) single nucleotide variant Inborn genetic diseases [RCV003358475] Chr2:102189270 [GRCh38]
Chr2:102805730 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.1127C>A (p.Thr376Asn) single nucleotide variant Inborn genetic diseases [RCV003376138] Chr2:102226033 [GRCh38]
Chr2:102842493 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.437G>T (p.Cys146Phe) single nucleotide variant Inborn genetic diseases [RCV003371094] Chr2:102192068 [GRCh38]
Chr2:102808528 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.871C>T (p.Arg291Trp) single nucleotide variant Inborn genetic diseases [RCV003353635] Chr2:102219897 [GRCh38]
Chr2:102836357 [GRCh37]
Chr2:2q12.1
uncertain significance
NM_003854.4(IL1RL2):c.800A>G (p.Asn267Ser) single nucleotide variant Inborn genetic diseases [RCV003386022] Chr2:102219028 [GRCh38]
Chr2:102835488 [GRCh37]
Chr2:2q12.1
uncertain significance
GRCh37/hg19 2q11.2-12.2(chr2:101933587-106547126)x1 copy number loss not provided [RCV003484827] Chr2:101933587..106547126 [GRCh37]
Chr2:2q11.2-12.2
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:933
Count of miRNA genes:497
Interacting mature miRNAs:550
Transcripts:ENST00000264257, ENST00000421464, ENST00000441515, ENST00000481806, ENST00000539491
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH120754  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372102,851,970 - 102,852,313UniSTSGRCh37
Build 362102,218,402 - 102,218,745RGDNCBI36
Celera297,053,179 - 97,053,522RGD
Cytogenetic Map2q12UniSTS
HuRef296,615,961 - 96,616,304UniSTS
TNG Radiation Hybrid Map260805.0UniSTS
STS-U49065  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372102,855,691 - 102,855,806UniSTSGRCh37
Build 362102,222,123 - 102,222,238RGDNCBI36
Celera297,056,900 - 97,057,015RGD
Cytogenetic Map2q12UniSTS
HuRef296,619,682 - 96,619,797UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 14 102 13 10 937 1 28 96 105 5 2 501
Low 1133 858 1472 552 198 396 1219 377 1427 332 888 1266 165 931 589 1
Below cutoff 1224 2042 129 40 1179 41 1978 1760 2134 33 427 137 1 271 1676

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001351446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001351447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001351448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001351449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001351450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006712820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006712822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011512096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017005174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017005175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017005176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017005177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017005180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047446164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047446165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047446166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007083520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007083521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008486576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008486577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008486578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_923053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC007248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC007271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF284434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC107064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA448166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ131903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U49065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000264257   ⟹   ENSP00000264257
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2102,187,023 - 102,240,002 (+)Ensembl
RefSeq Acc Id: ENST00000421464   ⟹   ENSP00000387611
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2102,187,314 - 102,201,582 (+)Ensembl
RefSeq Acc Id: ENST00000441515   ⟹   ENSP00000413348
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2102,187,015 - 102,239,351 (+)Ensembl
RefSeq Acc Id: ENST00000481806
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2102,187,006 - 102,239,338 (+)Ensembl
RefSeq Acc Id: NM_001351446   ⟹   NP_001338375
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,314 - 102,240,002 (+)NCBI
T2T-CHM13v2.02102,645,600 - 102,698,266 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001351447   ⟹   NP_001338376
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,186,973 - 102,240,002 (+)NCBI
T2T-CHM13v2.02102,645,259 - 102,698,266 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001351448   ⟹   NP_001338377
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,186,973 - 102,240,002 (+)NCBI
T2T-CHM13v2.02102,645,259 - 102,698,266 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001351449   ⟹   NP_001338378
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,240,002 (+)NCBI
T2T-CHM13v2.02102,645,309 - 102,698,266 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001351450   ⟹   NP_001338379
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,240,002 (+)NCBI
T2T-CHM13v2.02102,645,309 - 102,698,266 (+)NCBI
Sequence:
RefSeq Acc Id: NM_003854   ⟹   NP_003845
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,240,002 (+)NCBI
GRCh372102,803,433 - 102,856,462 (+)NCBI
Build 362102,169,865 - 102,222,243 (+)NCBI Archive
Celera297,004,649 - 97,057,020 (+)RGD
HuRef296,567,290 - 96,619,802 (+)ENTREZGENE
CHM1_12102,807,775 - 102,860,073 (+)NCBI
T2T-CHM13v2.02102,645,309 - 102,698,266 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006712822   ⟹   XP_006712885
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,189,176 - 102,240,002 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011512091   ⟹   XP_011510393
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,240,002 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011512092   ⟹   XP_011510394
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,239,283 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011512093   ⟹   XP_011510395
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,240,002 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011512094   ⟹   XP_011510396
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,314 - 102,240,002 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011512096   ⟹   XP_011510398
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,240,002 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017005174   ⟹   XP_016860663
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,243,086 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047446164   ⟹   XP_047302120
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,314 - 102,240,002 (+)NCBI
RefSeq Acc Id: XM_047446165   ⟹   XP_047302121
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,240,002 (+)NCBI
RefSeq Acc Id: XM_047446166   ⟹   XP_047302122
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,189,233 - 102,240,002 (+)NCBI
RefSeq Acc Id: XM_054344347   ⟹   XP_054200322
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,309 - 102,698,266 (+)NCBI
RefSeq Acc Id: XM_054344348   ⟹   XP_054200323
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,309 - 102,697,547 (+)NCBI
RefSeq Acc Id: XM_054344349   ⟹   XP_054200324
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,309 - 102,701,349 (+)NCBI
RefSeq Acc Id: XM_054344350   ⟹   XP_054200325
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,309 - 102,698,266 (+)NCBI
RefSeq Acc Id: XM_054344351   ⟹   XP_054200326
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,600 - 102,698,266 (+)NCBI
RefSeq Acc Id: XM_054344352   ⟹   XP_054200327
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,600 - 102,698,266 (+)NCBI
RefSeq Acc Id: XM_054344353   ⟹   XP_054200328
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,309 - 102,698,266 (+)NCBI
RefSeq Acc Id: XM_054344354   ⟹   XP_054200329
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,309 - 102,698,266 (+)NCBI
RefSeq Acc Id: XM_054344355   ⟹   XP_054200330
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,647,463 - 102,698,266 (+)NCBI
RefSeq Acc Id: XM_054344356   ⟹   XP_054200331
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,647,520 - 102,698,266 (+)NCBI
RefSeq Acc Id: XR_007083520
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,222,578 (+)NCBI
RefSeq Acc Id: XR_007083521
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,225,952 (+)NCBI
RefSeq Acc Id: XR_008486576
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,309 - 102,680,842 (+)NCBI
RefSeq Acc Id: XR_008486577
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,309 - 102,684,216 (+)NCBI
RefSeq Acc Id: XR_008486578
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02102,645,309 - 102,684,248 (+)NCBI
RefSeq Acc Id: XR_923053
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,187,023 - 102,225,984 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001338375 (Get FASTA)   NCBI Sequence Viewer  
  NP_001338376 (Get FASTA)   NCBI Sequence Viewer  
  NP_001338377 (Get FASTA)   NCBI Sequence Viewer  
  NP_001338378 (Get FASTA)   NCBI Sequence Viewer  
  NP_001338379 (Get FASTA)   NCBI Sequence Viewer  
  NP_003845 (Get FASTA)   NCBI Sequence Viewer  
  XP_006712885 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510393 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510394 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510395 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510396 (Get FASTA)   NCBI Sequence Viewer  
  XP_011510398 (Get FASTA)   NCBI Sequence Viewer  
  XP_016860663 (Get FASTA)   NCBI Sequence Viewer  
  XP_047302120 (Get FASTA)   NCBI Sequence Viewer  
  XP_047302121 (Get FASTA)   NCBI Sequence Viewer  
  XP_047302122 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200322 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200323 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200324 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200325 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200326 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200327 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200328 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200329 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200330 (Get FASTA)   NCBI Sequence Viewer  
  XP_054200331 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB53237 (Get FASTA)   NCBI Sequence Viewer  
  AAG21368 (Get FASTA)   NCBI Sequence Viewer  
  AAI07065 (Get FASTA)   NCBI Sequence Viewer  
  AAX81989 (Get FASTA)   NCBI Sequence Viewer  
  AAY15046 (Get FASTA)   NCBI Sequence Viewer  
  AAZ38712 (Get FASTA)   NCBI Sequence Viewer  
  BAG37734 (Get FASTA)   NCBI Sequence Viewer  
  EAX01798 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000264257
  ENSP00000264257.2
  ENSP00000387611.1
  ENSP00000413348
  ENSP00000413348.2
GenBank Protein Q9HB29 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_003845   ⟸   NM_003854
- Peptide Label: isoform a precursor
- UniProtKB: Q53TU8 (UniProtKB/Swiss-Prot),   Q45H74 (UniProtKB/Swiss-Prot),   Q13525 (UniProtKB/Swiss-Prot),   A4FU63 (UniProtKB/Swiss-Prot),   Q587I8 (UniProtKB/Swiss-Prot),   Q9HB29 (UniProtKB/Swiss-Prot),   B2RCY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006712885   ⟸   XM_006712822
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_011510394   ⟸   XM_011512092
- Peptide Label: isoform X2
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011510398   ⟸   XM_011512096
- Peptide Label: isoform X7
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011510393   ⟸   XM_011512091
- Peptide Label: isoform X1
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011510395   ⟸   XM_011512093
- Peptide Label: isoform X4
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011510396   ⟸   XM_011512094
- Peptide Label: isoform X5
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016860663   ⟸   XM_017005174
- Peptide Label: isoform X3
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001338378   ⟸   NM_001351449
- Peptide Label: isoform d
- Sequence:
RefSeq Acc Id: NP_001338379   ⟸   NM_001351450
- Peptide Label: isoform d
- Sequence:
RefSeq Acc Id: NP_001338376   ⟸   NM_001351447
- Peptide Label: isoform b
- Sequence:
RefSeq Acc Id: NP_001338377   ⟸   NM_001351448
- Peptide Label: isoform c
- Sequence:
RefSeq Acc Id: NP_001338375   ⟸   NM_001351446
- Peptide Label: isoform a precursor
- UniProtKB: Q9HB29 (UniProtKB/Swiss-Prot),   Q53TU8 (UniProtKB/Swiss-Prot),   Q45H74 (UniProtKB/Swiss-Prot),   Q13525 (UniProtKB/Swiss-Prot),   A4FU63 (UniProtKB/Swiss-Prot),   Q587I8 (UniProtKB/Swiss-Prot),   B2RCY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000413348   ⟸   ENST00000441515
RefSeq Acc Id: ENSP00000387611   ⟸   ENST00000421464
RefSeq Acc Id: ENSP00000264257   ⟸   ENST00000264257
RefSeq Acc Id: XP_047302121   ⟸   XM_047446165
- Peptide Label: isoform X6
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047302120   ⟸   XM_047446164
- Peptide Label: isoform X1
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047302122   ⟸   XM_047446166
- Peptide Label: isoform X9
RefSeq Acc Id: XP_054200324   ⟸   XM_054344349
- Peptide Label: isoform X3
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054200329   ⟸   XM_054344354
- Peptide Label: isoform X7
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054200322   ⟸   XM_054344347
- Peptide Label: isoform X1
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054200325   ⟸   XM_054344350
- Peptide Label: isoform X4
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054200328   ⟸   XM_054344353
- Peptide Label: isoform X6
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054200323   ⟸   XM_054344348
- Peptide Label: isoform X2
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054200326   ⟸   XM_054344351
- Peptide Label: isoform X5
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054200327   ⟸   XM_054344352
- Peptide Label: isoform X1
- UniProtKB: B2RCY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054200330   ⟸   XM_054344355
- Peptide Label: isoform X8
RefSeq Acc Id: XP_054200331   ⟸   XM_054344356
- Peptide Label: isoform X9
Protein Domains
Ig-like   Ig-like C2-type   TIR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9HB29-F1-model_v2 AlphaFold Q9HB29 1-575 view protein structure

Promoters
RGD ID:6797638
Promoter ID:HG_KWN:34197
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell
Transcripts:OTTHUMT00000253290,   OTTHUMT00000331184,   OTTHUMT00000331185,   UC002TBT.1
Position:
Human AssemblyChrPosition (strand)Source
Build 362102,169,476 - 102,169,976 (+)MPROMDB
RGD ID:6861204
Promoter ID:EPDNEW_H3767
Type:initiation region
Name:IL1RL2_1
Description:interleukin 1 receptor like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382102,186,988 - 102,187,048EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:5999 AgrOrtholog
COSMIC IL1RL2 COSMIC
Ensembl Genes ENSG00000115598 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000264257 ENTREZGENE
  ENST00000264257.7 UniProtKB/Swiss-Prot
  ENST00000421464.1 UniProtKB/TrEMBL
  ENST00000441515 ENTREZGENE
  ENST00000441515.3 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.10140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000115598 GTEx
HGNC ID HGNC:5999 ENTREZGENE
Human Proteome Map IL1RL2 Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_rcpt_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_rcpt_I-typ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_rcpt_I/II-typ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:8808 UniProtKB/Swiss-Prot
NCBI Gene 8808 ENTREZGENE
OMIM 604512 OMIM
PANTHER INTERLEUKIN-1 RECEPTOR-LIKE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11890 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA29815 PharmGKB
PRINTS INTRLEUKN1R1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTRLKN1R12F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTRLKN1R1F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A4FU63 ENTREZGENE
  B2RCY7 ENTREZGENE, UniProtKB/TrEMBL
  C9K0I8_HUMAN UniProtKB/TrEMBL
  ILRL2_HUMAN UniProtKB/Swiss-Prot
  Q13525 ENTREZGENE
  Q45H74 ENTREZGENE
  Q53TU8 ENTREZGENE
  Q587I8 ENTREZGENE
  Q9HB29 ENTREZGENE
UniProt Secondary A4FU63 UniProtKB/Swiss-Prot
  Q13525 UniProtKB/Swiss-Prot
  Q45H74 UniProtKB/Swiss-Prot
  Q53TU8 UniProtKB/Swiss-Prot
  Q587I8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-19 IL1RL2  interleukin 1 receptor like 2    interleukin 1 receptor-like 2  Symbol and/or name change 5135510 APPROVED
2011-09-01 IL1RL2  interleukin 1 receptor-like 2  IL1RL2  interleukin 1 receptor-like 2  Symbol and/or name change 5135510 APPROVED