Il1rl2<sup>tm1(Myh6-cre)Mhzh</sup> (interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh) - Rat Genome Database

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Gene: Il1rl2tm1(Myh6-cre)Mhzh (interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh) Rattus norvegicus
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Symbol: Il1rl2tm1(Myh6-cre)Mhzh
Name: interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh
RGD ID: 126925159
Description: The expression of Il1rl2 was knockout by Cre-loxP system in cardiomyocytes.
ASSOCIATED WITH abnormal circulating chemokine level; abnormal circulating myoglobin level; abnormal nitric oxide homeostasis; ASSOCIATED WITH Myocardial Reperfusion Injury
Type: allele  of Il1rl2  
Previously known as: Il1rl2^[tm1(Myh6-cre)Mhzh]; interleukin 1 receptor-like 2; tm1, Mhzh
Is Marker For: Strains:   SD-Il1rl2tm1(Myh6-cre)Mhzh  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position: No map positions available.



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il1rl2tm1(Myh6-cre)MhzhRatMyocardial Reperfusion Injury  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 

1 to 12 of 12 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il1rl2tm1(Myh6-cre)MhzhRatabnormal circulating chemokine level  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatabnormal circulating myoglobin level  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatabnormal nitric oxide homeostasis  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatdecreased cardiomyocyte apoptosis  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatdecreased circulating lactate dehydrogenase level  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatdecreased circulating troponin level  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatdecreased circulating tumor necrosis factor level  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatdecreased interleukin-1 beta secretion  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatdecreased macrophage cell number  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatincreased cardiac muscle contractility  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatincreased left ventricle systolic pressure  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
Il1rl2tm1(Myh6-cre)MhzhRatoxidative stress  IMP 126925167compared to Wild Type in cardiopulmonary bypass modelRGD 
1 to 12 of 12 rows

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Reference Title
Reference Citation
1. Deficiency of Interleukin-36 Receptor Protected Cardiomyocytes from Ischemia-Reperfusion Injury in Cardiopulmonary Bypass. Luo C, etal., Med Sci Monit. 2020 Feb 12;26:e918933. doi: 10.12659/MSM.918933.


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The following Strains have been annotated to Il1rl2tm1(Myh6-cre)Mhzh
SD-Il1rl2tm1(Myh6-cre)Mhzh    










Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-05-13 Il1rl2tm1(Myh6-cre)Mhzh  interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh  Il1rl2tm1(Myh6-cre)Mhzh  interleukin 1 receptor-like 2; tm1, Mhzh  Name changed 629549 APPROVED