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Gene: Glp1r (glucagon-like peptide 1 receptor) Rattus norvegicus
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Symbol: Glp1r
Name: glucagon-like peptide 1 receptor
Description: Exhibits G protein-coupled peptide receptor activity and peptide hormone binding activity. Involved in several processes, including insulin secretion; learning or memory; and positive regulation of insulin secretion. Localizes to integral component of plasma membrane. Used to study hyperglycemia and hypertension. Biomarker of obesity. Orthologous to human GLP1R (glucagon like peptide 1 receptor); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Glip; GLP-1 receptor; GLP-1-R; GLP-1R; pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1; RATGL1RCP
Orthologs:
Homo sapiens (human) : GLP1R (glucagon like peptide 1 receptor)  HGNC  Alliance
Mus musculus (house mouse) : Glp1r (glucagon-like peptide 1 receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glp1r (glucagon like peptide 1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : GLP1R (glucagon like peptide 1 receptor)
Canis lupus familiaris (dog) : GLP1R (glucagon like peptide 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glp1r (glucagon like peptide 1 receptor)
Sus scrofa (pig) : GLP1R (glucagon like peptide 1 receptor)
Chlorocebus sabaeus (African green monkey) : GLP1R (glucagon like peptide 1 receptor)
Heterocephalus glaber (naked mole-rat) : Glp1r (glucagon like peptide 1 receptor)
more info ...
Allele / Splice: Glp1rem1Mcwi   Glp1rem2Mcwi   Glp1rem3Mcwi  
Genetic Models: Lew-Glp1rem1Mcwi Lew-Glp1rem3Mcwi Lew-Glp1rem2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0209,586,075 - 9,626,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl209,586,075 - 9,626,228 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02011,768,479 - 11,808,416 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4209,225,881 - 9,264,184 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1209,226,107 - 9,264,411 (+)NCBI
Celera2010,499,202 - 10,536,348 (+)NCBICelera
Cytogenetic Map20p12NCBI
RH 3.4 Map20118.3RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Glp1r
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2703
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.