Gene: Glp1r (glucagon-like peptide 1 receptor) Rattus norvegicus
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Symbol: Glp1r
Name: glucagon-like peptide 1 receptor
Description: ENCODES a protein that exhibits G protein-coupled peptide receptor activity; peptide hormone binding; peptide receptor activity; INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway; associative learning; cAMP-mediated signaling; ASSOCIATED WITH increased heart rate; increased insulin secretion; increased systemic arterial blood pressure; ASSOCIATED WITH Diabetes Mellitus, Experimental ; hyperglycemia; hypertension; FOUND IN integral component of plasma membrane; plasma membrane; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; aldehydo-D-glucose
AGR Description: Exhibits G protein-coupled peptide receptor activity and peptide hormone binding activity; involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway, feeding behavior, and learning or memory; localizes to the integral component of plasma membrane; used to study hyperglycemia and hypertension; biomarker of obesity; orthologous to human GLP1R (glucagon like peptide 1 receptor).
Merged Description: Exhibits G protein-coupled peptide receptor activity and peptide hormone binding activity; involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway, feeding behavior, and learning or memory; localizes to the integral component of plasma membrane; used to study hyperglycemia and hypertension; biomarker of obesity; orthologous to human GLP1R (glucagon like peptide 1 receptor); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Glip; GLP-1 receptor; GLP-1-R; GLP-1R; pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1; RATGL1RCP
Orthologs:
Homo sapiens (human) : GLP1R (glucagon like peptide 1 receptor)  HGNC  Alliance
Mus musculus (house mouse) : Glp1r (glucagon-like peptide 1 receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glp1r (glucagon like peptide 1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : GLP1R (glucagon like peptide 1 receptor)
Canis lupus familiaris (dog) : GLP1R (glucagon like peptide 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glp1r (glucagon like peptide 1 receptor)
Sus scrofa (pig) : GLP1R (glucagon like peptide 1 receptor)
more info ...
Allele / Splice: Glp1rem1Mcwi   Glp1rem2Mcwi   Glp1rem3Mcwi  
Genetic Models: Lew-Glp1rem1Mcwi Lew-Glp1rem3Mcwi Lew-Glp1rem2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0209,586,075 - 9,626,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02011,768,479 - 11,808,416 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4209,225,881 - 9,264,184 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1209,226,107 - 9,264,411 (+)NCBI
Celera2010,499,202 - 10,536,348 (+)NCBICelera
Cytogenetic Map20p12NCBI
RH 3.4 Map20118.3RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Glp1r
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2703
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.