Gene: Trpc3 (transient receptor potential cation channel, subfamily C, member 3) Rattus norvegicus
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Symbol: Trpc3
Name: transient receptor potential cation channel, subfamily C, member 3
Description: ENCODES a protein that exhibits calcium activated cation channel activity; inositol 1,4,5 trisphosphate binding (ortholog); INVOLVED IN calcium ion transmembrane transport (ortholog); positive regulation of calcium ion transport into cytosol (ortholog); positive regulation of cardiac muscle hypertrophy in response to stress (ortholog); ASSOCIATED WITH Albuminuria; bipolar disorder (ortholog); hypertension (ortholog); FOUND IN integral component of plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,4,6-trinitrobenzenesulfonic acid
AGR Description: Exhibits calcium activated cation channel activity; predicted to be involved in several processes, including cation transport, positive regulation of calcium ion transport into cytosol, and positive regulation of cardiac muscle hypertrophy in response to stress; predicted to localize to the cation channel complex and integral component of plasma membrane; orthologous to human TRPC3 (transient receptor potential cation channel subfamily C member 3).
Merged Description: Exhibits calcium activated cation channel activity; predicted to be involved in several processes, including cation transport, positive regulation of calcium ion transport into cytosol, and positive regulation of cardiac muscle hypertrophy in response to stress; predicted to localize to the cation channel complex and integral component of plasma membrane; orthologous to human TRPC3 (transient receptor potential cation channel subfamily C member 3); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ion channel protein; short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3; transient receptor protein 3; trp-related protein 3; TrpC3c; Trrp3
Orthologs:
Homo sapiens (human) : TRPC3 (transient receptor potential cation channel subfamily C member 3)  HGNC  Alliance
Mus musculus (house mouse) : Trpc3 (transient receptor potential cation channel, subfamily C, member 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trpc3 (transient receptor potential cation channel subfamily C member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TRPC3 (transient receptor potential cation channel subfamily C member 3)
Canis lupus familiaris (dog) : TRPC3 (transient receptor potential cation channel subfamily C member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trpc3 (transient receptor potential cation channel subfamily C member 3)
Sus scrofa (pig) : TRPC3 (transient receptor potential cation channel subfamily C member 3)
more info ...
Allele / Splice: Trpc3em2Mcwi   Trpc3em1Mcwi  
Genetic Models: SS-Trpc3em1Mcwi SS-Trpc3em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02123,329,954 - 123,467,574 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02142,945,309 - 143,022,844 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42123,117,180 - 123,184,016 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12123,062,239 - 123,110,364 (-)NCBI
Celera2114,439,430 - 114,505,661 (-)NCBICelera
Cytogenetic Map2q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

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Genomics

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QTLs in Region (Rnor_6.0)
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Sequence

Nucleotide Sequences
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Strain Variation

Strain Sequence Variants (Rnor 5.0)
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Additional Information

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Nomenclature History
RGD Curation Notes
  
More on Trpc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61973
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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