Gene: Trpc3 (transient receptor potential cation channel, subfamily C, member 3) Rattus norvegicus
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Symbol: Trpc3
Name: transient receptor potential cation channel, subfamily C, member 3
Description: ENCODES a protein that exhibits calcium activated cation channel activity; inositol 1,4,5 trisphosphate binding (ortholog); INVOLVED IN calcium ion transmembrane transport (ortholog); positive regulation of calcium ion transport into cytosol (ortholog); positive regulation of cardiac muscle hypertrophy in response to stress (ortholog); ASSOCIATED WITH Albuminuria; bipolar disorder (ortholog); hypertension (ortholog); FOUND IN integral component of plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,4,6-trinitrobenzenesulfonic acid
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ion channel protein; short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3; transient receptor protein 3; trp-related protein 3; TrpC3c; Trrp3
Orthologs:
Homo sapiens (human) : TRPC3 (transient receptor potential cation channel subfamily C member 3)  HGNC  Alliance
Mus musculus (house mouse) : Trpc3 (transient receptor potential cation channel, subfamily C, member 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trpc3 (transient receptor potential cation channel subfamily C member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TRPC3 (transient receptor potential cation channel subfamily C member 3)
Canis lupus familiaris (dog) : TRPC3 (transient receptor potential cation channel subfamily C member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trpc3 (transient receptor potential cation channel subfamily C member 3)
more info ...
Allele / Splice: Trpc3em2Mcwi   Trpc3em1Mcwi  
Genetic Models: SS-Trpc3em1Mcwi SS-Trpc3em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02123,329,954 - 123,467,574 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02142,945,309 - 143,022,844 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42123,117,180 - 123,184,016 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12123,062,239 - 123,110,364 (-)NCBI
Celera2114,439,430 - 114,505,661 (-)NCBICelera
Cytogenetic Map2q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
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Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Trpc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61973
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-01-08
Status: ACTIVE



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