Strain Report - Rat Genome Database

Name: iNP- Npy em6Sage /Iusm
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: iNP-Npy^em6Sage/Iusm

Symbol:

iNP-Npy^em6Sage/Iusm

Strain:

iNP-Npy^em6Sage

Substrain:

Iusm

RGD ID:

11530028

Citation ID:

RRID:RGD_11530028

Ontology ID:

RS:0004214

Alleles:

Npy^em6Sage

Previously known as:

NP/Iusm-Npyem6Sage ; NP/Iusm-Npy^em6Sage

Type:

mutant

Source:

Department of Gastroenterology, Indiana University School of Medicine, Indianapolis, IN 46202, USA

Origin:

These ZFN mutant rats were produced by injecting zinc finger nuclease targeting rat Npy into iNP/Iusm embryos. A 26-bp deletion, including 6 bp in intron 1 and 20 bp in exon 2 in rat Npy was created in the mutant founders. These mutant founders were backcrossed with iNP/Iusm to produce heterozygous offspring, which were then intercrossed to produce homozygous and heterozygous offspring.

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	78,881,294 - 78,888,495	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	4	79,557,856 - 79,565,059	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	4	144,233,753 - 144,240,956	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	4	78,038,013 - 78,045,187	RGD_MAPPER_PIPELINE	RGSC3.4

Mutant Strains

iNP-Npyem6Sage +/-/Iusm

iNP-Npyem6Sage-/-/Iusm

Annotation Click to see Annotation Detail View

References

References - curated

#	Reference Title	Reference Citation
1.	Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight.	Qiu B, etal., J Genet Genomics. 2016 Jul 20;43(7):421-30. doi: 10.1016/j.jgg.2016.04.010. Epub 2016 Apr 29.

Region

Additional Information

Nomenclature History

Date	Current Symbol	Previous Symbol	Description	Reference	Status
2023-05-02	iNP-Npy^em6Sage/Iusm	NP/Iusm-Npy^em6Sage	Symbol and/or name change	68913	APPROVED
2018-03-14	NP/Iusm-Npy^em6Sage	NP/Iusm-Npy^em6Sage	Symbol updated	68687	APPROVED
2018-03-14	NP/Iusm-Npy^em6Sage	NP/Iusm-Npy^em6Sage	Symbol updated	68687	APPROVED
2016-08-26	NP/Iusm-Npy^em6Sage	NP/Iusm-Npy^em6Sage	Name updated	68913	APPROVED
2016-08-26	NP/Iusm-Npy^em6Sage	NP/Iusm-Npy^em6Sage	Name updated	68913	APPROVED
2016-08-26	NP/Iusm-Npy^em6Sage	NP/Iusm-Npy^em6Sage	Name updated	68913	APPROVED
2016-08-26	NP/Iusm-Npy^em6Sage	NP/Iusm-Npy^em6Sage	Name updated	68913	APPROVED
2016-08-26	NP/Iusm-Npy^em6Sage	NP/Iusm-Npy^em6Sage	Name updated	68913	APPROVED
2016-08-26	NP/Iusm-Npy^em6Sage	NP-Npy^em6Sage	Name updated	68913	APPROVED
2016-08-26	NP/Iusm-Npy^em6Sage	NP-Npy^em6Sage	Symbol updated	68687	APPROVED
2016-08-26	NP/Iusm-Npy^em6Sage	NP-Npy^em6Sage	Name updated	68913	APPROVED
2016-08-26	NP/Iusm-Npy^em6Sage	NP-Npy^em6Sage	Symbol updated	68687	APPROVED
2016-08-19	NP-Npy^em6Sage	NP-Npy^em6Sage	Name updated	68913	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: iNP-Npyem6Sage/Iusm

Strain: iNP-Npy^em6Sage/Iusm