Strain: WKY-Slc39a12em77Tja+/-

Symbol: WKY-Slc39a12em77Tja+/-
Strain: WKY-Slc39a12em77+/WKY-Slc39a12em77-
Substrain: Tja
Full Name: WKY-Slc39a12em77Tja+/WKY-Slc39a12em77Tja-
Ontology ID: RS:0004054
Alleles: Slc39a12em77Tja
Also known as: WKY-Slc39a12em77Tja+/-; WKY-Slc39a12em77Tja+/WKY-Slc39a12em77Tja-
Type: mutant
Source: MRC Clinical Centre, London, UK
Origin: ZFN mutant founders were backcrossed with WKY/Cruk to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders. The resulting mutation 77 has a stop codon, 15 amino acids from the ZFN-binding site, that resulted in a 490 amino acids (54 kDa) truncated protein, 198 amino acids smaller than the WT protein.
Genetic Status: Heterozygous
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01781,455,731 - 81,541,742RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01783,202,775 - 83,288,616RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41788,525,527 - 88,605,947RGD_MAPPER_PIPELINERGSC3.4

Disease Annotations
Phenotype Annotations
Experimental Data Annotations
References - curated
RGD Disease Portals


Additional Information

Nomenclature History
More on this Strain
Strain Nomenclature
Strain Registration

RGD Object Information
RGD ID: 10401845
Created: 2015-10-08
Species: Rattus norvegicus
Last Modified: 2015-10-08
Status: ACTIVE