Gene: Mertk (MER proto-oncogene, tyrosine kinase) Rattus norvegicus
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Symbol: Mertk
Name: MER proto-oncogene, tyrosine kinase
Description: ENCODES a protein that exhibits ATP binding (inferred); INVOLVED IN phagocytosis; protein phosphorylation; apoptotic cell clearance (ortholog); ASSOCIATED WITH carcinoma (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN photoreceptor outer segment; cytoplasm (ortholog); extracellular space (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride
AGR Description: Predicted to have Wnt-protein binding activity and transmembrane receptor protein tyrosine kinase activity; involved in phagocytosis and protein phosphorylation; localizes to the photoreceptor outer segment; orthologous to human MERTK (MER proto-oncogene, tyrosine kinase).
Merged Description: Predicted to have Wnt-protein binding activity and transmembrane receptor protein tyrosine kinase activity; involved in phagocytosis and protein phosphorylation; localizes to the photoreceptor outer segment; orthologous to human MERTK (MER proto-oncogene, tyrosine kinase); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: c-mer proto-oncogene tyrosine kinase; proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase Mer; Rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; tyrosine-protein kinase Mer
Orthologs:
Homo sapiens (human) : MERTK (MER proto-oncogene, tyrosine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Mertk (MER proto-oncogene tyrosine kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mertk (MER proto-oncogene, tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : MERTK (MER proto-oncogene, tyrosine kinase)
Canis lupus familiaris (dog) : MERTK (MER proto-oncogene, tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mertk (MER proto-oncogene, tyrosine kinase)
Sus scrofa (pig) : MERTK (MER proto-oncogene, tyrosine kinase)
more info ...
Is Marker For: Strains:   RCS/Kyo   (LE x RCS-p+/LavRrrc)F1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03121,235,230 - 121,340,932 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03128,669,534 - 128,777,078 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43116,308,387 - 116,416,414 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13116,213,959 - 116,321,987 (+)NCBI
Celera3114,768,654 - 114,872,632 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

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Sequence

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Strain Sequence Variants (Rnor 5.0)

Additional Information

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RGD Curation Notes
  
More on Mertk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69283
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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