Strain Report - Rat Genome Database

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Strain: DA-Tph2em3Mcwi

Symbol: DA-Tph2em3Mcwi
Strain: DA-Tph2em3
Substrain: Mcwi
RGD ID: 10402822
Citation ID: RRID:RGD_10402822
Ontology ID: RS:0004070
Alleles: Tph2em3Mcwi
Also Known As: DA-Tph2em2Mcwi; DA-Tph2em3Mcwi; DA-Tph2^[em3Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence CATGGCTCCGACCCCctctacACCCCGGAACCG into DA/OlaHsd rat embryos. The resulting mutation is a 11-bp frameshift deletion in exon 7.
Last Known Status: Cryorecovery (as of 2017-01-26)
Genotyping Protocol Download Genotyping Protocol
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2750,685,694 - 50,789,424RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0758,112,644 - 58,112,654RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0758,053,268 - 58,157,949RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4754,321,033 - 54,430,706RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Tph2em3Mcwi-var1 chr7 58112644 58112654 GGGGTGTAGAG - deletion Rnor_6.0

Additional Information